메뉴 건너뛰기




Volumn 44, Issue 5, 2012, Pages 545-551

Common variants at 12q14 and 12q24 are associated with hippocampal volume

(82)  Bis, Joshua C a   Decarli, Charles b,c   Smith, Albert Vernon d,e   Van Der Lijn, Fedde f   Crivello, Fabrice g,h,i   Fornage, Myriam j,k   Debette, Stephanie l,m,n   Shulman, Joshua M o,p   Schmidt, Helena q   Srikanth, Velandai r,s   Schuur, Maaike f   Yu, Lei t   Choi, Seung Hoan u   Sigurdsson, Sigurdur d   Verhaaren, Benjamin F J f   Destefano, Anita L n,u,v   Lambert, Jean Charles l,w,x   Jack, Clifford R y   Struchalin, Maksim f   Stankovich, Jim s   more..

h CNRS   (France)
i DIF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

SITAGLIPTIN;

EID: 84860326795     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2237     Document Type: Article
Times cited : (194)

References (51)
  • 2
    • 0037038815 scopus 로고    scopus 로고
    • Use of neuroimaging to detect early brain changes in people at genetic risk for Alzheimer's disease
    • DOI 10.1016/S0169-409X(02)00151-5, PII S0169409X02001515
    • Small, G.W. Use of neuroimaging to detect early brain changes in people at genetic risk for Alzheimer's disease. Adv. Drug Deliv. Rev. 54, 1561-1566 (2002). (Pubitemid 35346830)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.12 , pp. 1561-1566
    • Small, G.W.1
  • 4
    • 43549091613 scopus 로고    scopus 로고
    • Association of plasma total homocysteine levels with subclinical brain injury: Cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study
    • DOI 10.1001/archneur.65.5.642
    • Seshadri, S. et al. Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study. Arch. Neurol. 65, 642-649 (2008). (Pubitemid 351679660)
    • (2008) Archives of Neurology , vol.65 , Issue.5 , pp. 642-649
    • Seshadri, S.1    Wolf, P.A.2    Beiser, A.S.3    Selhub, J.4    Au, R.5    Jacques, P.F.6    Yoshita, M.7    Rosenberg, I.H.8    D'Agostino, R.B.9    DeCarli, C.10
  • 5
    • 0035686219 scopus 로고    scopus 로고
    • Heritability of hippocampal size in elderly twin men: Equivalent influence from genes and environment
    • DOI 10.1002/hipo.1091
    • Sullivan, E.V., Pfefferbaum, A., Swan, G.E. & Carmelli, D. Heritability of hippocampal size in elderly twin men: equivalent influence from genes and environment. Hippocampus 11, 754-762 (2001). (Pubitemid 34065505)
    • (2001) Hippocampus , vol.11 , Issue.6 , pp. 754-762
    • Sullivan, E.V.1    Pfefferbaum, A.2    Swan, G.E.3    Carmelli, D.4
  • 6
    • 63449100039 scopus 로고    scopus 로고
    • Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts
    • Psaty, B.M. et al. Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ. Cardiovasc. Genet. 2, 73-80 (2009).
    • (2009) Circ. Cardiovasc. Genet , vol.2 , pp. 73-80
    • Psaty, B.M.1
  • 8
    • 78651232076 scopus 로고    scopus 로고
    • Characterization of a novel interaction between Bcl-2 members Diva and Harakiri
    • Sborgi, L., Barrera-Vilarmau, S., Obregon, P. & de Alba, E. Characterization of a novel interaction between Bcl-2 members Diva and Harakiri. PLoS ONE 5, e15575 (2010).
    • (2010) PLoS ONE , vol.5
    • Sborgi, L.1    Barrera-Vilarmau, S.2    Obregon, P.3    De Alba, E.4
  • 9
    • 77954219292 scopus 로고    scopus 로고
    • Inflammatory apoptotic, and survival gene signaling in Alzheimer's disease. A review on the bioactivity of neuroprotectin D1 and apoptosis
    • Lukiw, W.J. & Bazan, N.G. Inflammatory, apoptotic, and survival gene signaling in Alzheimer's disease. A review on the bioactivity of neuroprotectin D1 and apoptosis. Mol. Neurobiol. 42, 10-16 (2010).
    • (2010) Mol. Neurobiol , vol.42 , pp. 10-16
    • Lukiw, W.J.1    Bazan, N.G.2
  • 10
    • 0030970085 scopus 로고    scopus 로고
    • Harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)
    • DOI 10.1093/emboj/16.7.1686
    • Inohara, N., Ding, L., Chen, S. & Nunez, G. harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-XL. EMBO J. 16, 1686-1694 (1997). (Pubitemid 27151963)
    • (1997) EMBO Journal , vol.16 , Issue.7 , pp. 1686-1694
    • Inohara, N.1    Ding, L.2    Chen, S.3    Nunez, G.4
  • 11
    • 0033583218 scopus 로고    scopus 로고
    • The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid β protein
    • Imaizumi, K. et al. The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid β protein. J. Biol. Chem. 274, 7975-7981 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 7975-7981
    • Imaizumi, K.1
  • 12
    • 29244488546 scopus 로고    scopus 로고
    • Brain ischemia/reperfusion-induced expression of DP5 and its interaction with Bcl-2, thus freeing Bax from Bcl-2/Bax dimmers are mediated by c-Jun N-terminal kinase (JNK) pathway
    • Guan, Q.H., Pei, D.S., Xu, T.L. & Zhang, G.Y. Brain ischemia/reperfusion-induced expression of DP5 and its interaction with Bcl-2, thus freeing Bax from Bcl-2/Bax dimmers are mediated by c-Jun N-terminal kinase (JNK) pathway. Neurosci. Lett. 393, 226-230 (2006).
    • (2006) Neurosci. Lett , vol.393 , pp. 226-230
    • Guan, Q.H.1    Pei, D.S.2    Xu, T.L.3    Zhang, G.Y.4
  • 13
    • 78649997930 scopus 로고    scopus 로고
    • The role of caspases in Alzheimer's disease; Potential novel therapeutic opportunities
    • Rohn, T.T. The role of caspases in Alzheimer's disease; potential novel therapeutic opportunities. Apoptosis 15, 1403-1409 (2010).
    • (2010) Apoptosis , vol.15 , pp. 1403-1409
    • Rohn, T.T.1
  • 14
    • 58049088976 scopus 로고    scopus 로고
    • Think locally: Control of ubiquitin-dependent protein degradation in neurons
    • Segref, A. & Hoppe, T. Think locally: control of ubiquitin-dependent protein degradation in neurons. EMBO Rep. 10, 44-50 (2009).
    • (2009) EMBO Rep , vol.10 , pp. 44-50
    • Segref, A.1    Hoppe, T.2
  • 16
    • 3142708002 scopus 로고    scopus 로고
    • An SCF-like ubiquitin ligase complex that controls presynaptic differentiation
    • DOI 10.1038/nature02647
    • Liao, E.H., Hung, W., Abrams, B. & Zhen, M. An SCF-like ubiquitin ligase complex that controls presynaptic differentiation. Nature 430, 345-350 (2004). (Pubitemid 38937741)
    • (2004) Nature , vol.430 , Issue.6997 , pp. 345-350
    • Liao, E.H.1    Hung, W.2    Abrams, B.3    Zhen, M.4
  • 17
    • 79958046350 scopus 로고    scopus 로고
    • An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning
    • Litterman, N. et al. An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. PLoS Biol. 9, e1001060 (2011).
    • (2011) PLoS Biol , vol.9
    • Litterman, N.1
  • 18
    • 55449112450 scopus 로고    scopus 로고
    • High-resolution mapping of expression-QTLs yields insight into human gene regulation
    • Veyrieras, J.B. et al. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 4, e1000214 (2008).
    • (2008) PLoS Genet , vol.4
    • Veyrieras, J.B.1
  • 19
    • 45149108420 scopus 로고    scopus 로고
    • Mapping the genetic architecture of gene expression in human liver
    • Schadt, E.E. et al. Mapping the genetic architecture of gene expression in human liver. PLoS Biol. 6, e107 (2008).
    • (2008) PLoS Biol , vol.6
    • Schadt, E.E.1
  • 21
    • 55449112185 scopus 로고    scopus 로고
    • Genome-wide associations of gene expression variation in humans
    • Stranger, B.E. et al. Genome-wide associations of gene expression variation in humans. PLoS Genet. 1, e78 (2005).
    • (2005) PLoS Genet , vol.1
    • Stranger, B.E.1
  • 26
    • 80053643245 scopus 로고    scopus 로고
    • Downregulation of Wnt/β-catenin signaling causes degeneration of hippocampal neurons in vivo
    • Kim, H. et al. Downregulation of Wnt/β-catenin signaling causes degeneration of hippocampal neurons in vivo. Neurobiol. Aging 32, 2316.e1-2316.e15 (2011).
    • (2011) Neurobiol. Aging , vol.32
    • Kim, H.1
  • 27
    • 65649086782 scopus 로고    scopus 로고
    • Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus
    • Gogolla, N., Galimberti, I., Deguchi, Y. & Caroni, P. Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus. Neuron 62, 510-525 (2009).
    • (2009) Neuron , vol.62 , pp. 510-525
    • Gogolla, N.1    Galimberti, I.2    Deguchi, Y.3    Caroni, P.4
  • 28
    • 79953277743 scopus 로고    scopus 로고
    • CR1 is associated with amyloid plaque burden and age-related cognitive decline
    • Chibnik, L.B. et al. CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann. Neurol. 69, 560-569 (2011).
    • (2011) Ann. Neurol , vol.69 , pp. 560-569
    • Chibnik, L.B.1
  • 29
    • 77950660341 scopus 로고    scopus 로고
    • Whole transcriptome analysis of the hippocampus: Toward a molecular portrait of epileptogenesis
    • Okamoto, O.K. et al. Whole transcriptome analysis of the hippocampus: toward a molecular portrait of epileptogenesis. BMC Genomics 11, 230 (2010).
    • (2010) BMC Genomics , vol.11 , pp. 230
    • Okamoto, O.K.1
  • 30
    • 0029819763 scopus 로고    scopus 로고
    • TGF-β1 protects hippocampal neurons against degeneration caused by transient global ischemia.Dose-response relationship and potential neuroprotective mechanisms
    • discussion 1615, 1996
    • Henrich-Noack, P., Prehn, J.H. & Krieglstein, J. TGF-β1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms. Stroke 27, 1609-1614, discussion 1615 (1996).
    • Stroke , vol.27 , pp. 1609-1614
    • Henrich-Noack, P.1    Prehn, J.H.2    Krieglstein, J.3
  • 31
    • 78549252392 scopus 로고    scopus 로고
    • Identification of differential protein interactors of lamin A and progerin
    • Kubben, N. et al. Identification of differential protein interactors of lamin A and progerin. Nucleus 1, 513-525 (2010).
    • (2010) Nucleus , vol.1 , pp. 513-525
    • Kubben, N.1
  • 32
    • 0033619675 scopus 로고    scopus 로고
    • Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides
    • DOI 10.1016/S0167-0115(99)00089-0, PII S0167011599000890
    • Mentlein, R. Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides. Regul. Pept. 85, 9-24 (1999). (Pubitemid 29505281)
    • (1999) Regulatory Peptides , vol.85 , Issue.1 , pp. 9-24
    • Mentlein, R.1
  • 33
    • 44149122563 scopus 로고    scopus 로고
    • GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by β-amyloid
    • Gault, V.A. & Holscher, C. GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by β-amyloid. Eur. J. Pharmacol. 587, 112-117 (2008).
    • (2008) Eur. J. Pharmacol , vol.587 , pp. 112-117
    • Gault, V.A.1    Holscher, C.2
  • 34
    • 0023498924 scopus 로고
    • Immunolocalization of dipeptidyl aminopeptidase (DAP IV) in the developing human brain
    • Bernstein, H.G., Schon, E., Ansorge, S., Rose, I. & Dorn, A. Immunolocalization of dipeptidyl aminopeptidase (DAP IV) in the developing human brain. Int. J. Dev. Neurosci. 5, 237-242 (1987).
    • (1987) Int. J. Dev. Neurosci , vol.5 , pp. 237-242
    • Bernstein, H.G.1    Schon, E.2    Ansorge, S.3    Rose, I.4    Dorn, A.5
  • 35
    • 80052096595 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome
    • Lamers, D. et al. Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes 60, 1917-1925 (2011).
    • (2011) Diabetes , vol.60 , pp. 1917-1925
    • Lamers, D.1
  • 36
    • 26444458863 scopus 로고    scopus 로고
    • Central obesity and the aging brain
    • DOI 10.1001/archneur.62.10.1545
    • Jagust, W., Harvey, D., Mungas, D. & Haan, M. Central obesity and the aging brain. Arch. Neurol. 62, 1545-1548 (2005). (Pubitemid 41434559)
    • (2005) Archives of Neurology , vol.62 , Issue.10 , pp. 1545-1548
    • Jagust, W.1    Harvey, D.2    Mungas, D.3    Haan, M.4
  • 37
    • 79751479118 scopus 로고    scopus 로고
    • Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
    • Hamilton, A., Patterson, S., Porter, D., Gault, V.A. & Holscher, C. Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain. J. Neurosci. Res. 89, 481-489 (2011).
    • (2011) J. Neurosci. Res , vol.89 , pp. 481-489
    • Hamilton, A.1    Patterson, S.2    Porter, D.3    Gault, V.A.4    Holscher, C.5
  • 38
    • 69549128161 scopus 로고    scopus 로고
    • Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system
    • Hamilton, A. & Holscher, C. Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system. Neuroreport 20, 1161-1166 (2009).
    • (2009) Neuroreport , vol.20 , pp. 1161-1166
    • Hamilton, A.1    Holscher, C.2
  • 40
    • 77954138932 scopus 로고    scopus 로고
    • Astn2 a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration
    • Wilson, P.M., Fryer, R.H., Fang, Y. & Hatten, M.E. Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration. J. Neurosci. 30, 8529-8540 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 8529-8540
    • Wilson, P.M.1    Fryer, R.H.2    Fang, Y.3    Hatten, M.E.4
  • 41
    • 0025409032 scopus 로고
    • Neuron-glia interactions of rat hippocampal cells in vitro: Glial-guided neuronal migration and neuronal regulation of glial differentiation
    • Gasser, U.E. & Hatten, M.E. Neuron-glia interactions of rat hippocampal cells in vitro: glial-guided neuronal migration and neuronal regulation of glial differentiation. J. Neurosci. 10, 1276-1285 (1990).
    • (1990) J. Neurosci , vol.10 , pp. 1276-1285
    • Gasser, U.E.1    Hatten, M.E.2
  • 42
    • 78549264026 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
    • Lambert, J.C. et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat. Genet. 41, 1094-1099 (2009).
    • (2009) Nat. Genet , vol.41 , pp. 1094-1099
    • Lambert, J.C.1
  • 43
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • Harold, D. et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat. Genet. 41, 1088-1093 (2009).
    • (2009) Nat. Genet , vol.41 , pp. 1088-1093
    • Harold, D.1
  • 44
    • 79955484414 scopus 로고    scopus 로고
    • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
    • Hollingworth, P. et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat. Genet. 43, 429-435 (2011).
    • (2011) Nat. Genet , vol.43 , pp. 429-435
    • Hollingworth, P.1
  • 45
    • 79955464911 scopus 로고    scopus 로고
    • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
    • Naj, A.C. et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat. Genet. 43, 436-441 (2011).
    • (2011) Nat. Genet , vol.43 , pp. 436-441
    • Naj, A.C.1
  • 46
    • 77952307991 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic loci associated with Alzheimer disease
    • Seshadri, S. et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. J. Am. Med. Assoc. 303, 1832-1840 (2010).
    • (2010) J. Am. Med. Assoc , vol.303 , pp. 1832-1840
    • Seshadri, S.1
  • 47
    • 77955036445 scopus 로고    scopus 로고
    • Association of CR1 CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals
    • Corneveaux, J.J. et al. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum. Mol. Genet. 19, 3295-3301 (2010).
    • (2010) Hum. Mol. Genet , vol.19 , pp. 3295-3301
    • Corneveaux, J.J.1
  • 48
    • 54549100129 scopus 로고    scopus 로고
    • Hippocampus segmentation in MR images using atlas registration, voxel classification, and graph cuts
    • van der Lijn, F., den Heijer, T., Breteler, M.M. & Niessen, W.J. Hippocampus segmentation in MR images using atlas registration, voxel classification, and graph cuts. Neuroimage 43, 708-720 (2008).
    • (2008) Neuroimage , vol.43 , pp. 708-720
    • Van Der Lijn, F.1    Den Heijer, T.2    Breteler, M.M.3    Niessen, W.J.4
  • 49
    • 77955894071 scopus 로고    scopus 로고
    • METAL:fast and efficient meta-analysis of genomewide association scans
    • Willer, C.J., Li, Y. & Abecasis, G.R. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 26, 2190-2191 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 50
    • 60549083544 scopus 로고    scopus 로고
    • An open access database of genome-wide association results
    • Johnson, A.D. & O'Donnell, C.J. An open access database of genome-wide association results. BMC Med. Genet. 10, 6 (2009).
    • (2009) BMC Med. Genet , vol.10 , pp. 6
    • Johnson, A.D.1    O'Donnell, C.J.2
  • 51
    • 84860351742 scopus 로고    scopus 로고
    • Identification of common variants associated with human hippocampal and intracranial volumes
    • published online ,15 April doi:10.1038/ng.2250
    • Stein, J.L. et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nat. Genet. published online (15 April 2012); doi:10.1038/ng.2250.
    • (2012) Nat. Genet.
    • Stein, J.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.