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Volumn 29, Issue 9, 2017, Pages 401-409

Hyperferritinemia and inflammation

Author keywords

Ferritin; Hemophagocytic lymphohistiocytosis; Hemophagocytosis; Iron; Macrophage activation

Indexed keywords

BIOLOGICAL MARKER; FERRITIN; FREE RADICAL; IRON;

EID: 85034223410     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxx031     Document Type: Article
Times cited : (397)

References (108)
  • 2
    • 84896353280 scopus 로고    scopus 로고
    • Coupling heme and iron metabolism via ferritin H chain
    • Gozzelino, R. and Soares, M. P. 2014. Coupling heme and iron metabolism via ferritin H chain. Antioxid. Redox Signal. 20:1754
    • (2014) Antioxid. Redox Signal , vol.20 , pp. 1754
    • Gozzelino, R.1    Soares, M.P.2
  • 3
    • 77956605615 scopus 로고    scopus 로고
    • Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway
    • Cohen, L. A., Gutierrez, L., Weiss, A. et al. 2010. Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. Blood 116:1574
    • (2010) Blood , vol.116 , pp. 1574
    • Cohen, L.A.1    Gutierrez, L.2    Weiss, A.3
  • 4
    • 34249047349 scopus 로고    scopus 로고
    • Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation
    • Kato, J., Kobune, M., Ohkubo, S. et al. 2007. Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation. Exp. Hematol. 35:879
    • (2007) Exp. Hematol , vol.35 , pp. 879
    • Kato, J.1    Kobune, M.2    Ohkubo, S.3
  • 5
    • 0030608152 scopus 로고    scopus 로고
    • The ferritins: molecular properties, iron storage function and cellular regulation
    • Harrison, P. M. and Arosio, P. 1996. The ferritins: molecular properties, iron storage function and cellular regulation. Biochim. Biophys. Acta 1275:161
    • (1996) Biochim. Biophys. Acta , vol.1275 , pp. 161
    • Harrison, P.M.1    Arosio, P.2
  • 6
    • 24044541042 scopus 로고    scopus 로고
    • The acute box cis-element in human heavy ferritin mRNA 5'-untranslated region is a unique translation enhancer that binds poly©-binding proteins
    • Thomson, A. M., Cahill, C. M., Cho, H. H. et al. 2005. The acute box cis-element in human heavy ferritin mRNA 5'-untranslated region is a unique translation enhancer that binds poly©-binding proteins. J. Biol. Chem. 280:30032
    • (2005) J. Biol. Chem , vol.280 , pp. 30032
    • Thomson, A.M.1    Cahill, C.M.2    Cho, H.H.3
  • 7
    • 0027358656 scopus 로고
    • Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: changes in transferrin uptake, iron handling and ferritin mRNA
    • Fahmy, M. and Young, S. P. 1993. Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: changes in transferrin uptake, iron handling and ferritin mRNA. Biochem. J. 296(Pt 1):175
    • (1993) Biochem. J , vol.296 , pp. 175
    • Fahmy, M.1    Young, S.P.2
  • 8
    • 33746691267 scopus 로고    scopus 로고
    • Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide
    • Mikhael, M., Kim, S. F., Schranzhofer, M. et al. 2006. Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide. FEBS J. 273:3828
    • (2006) FEBS J , vol.273 , pp. 3828
    • Mikhael, M.1    Kim, S.F.2    Schranzhofer, M.3
  • 9
    • 84929186045 scopus 로고    scopus 로고
    • Macrophages and iron trafficking at the birth and death of red cells
    • Korolnek, T. and Hamza, I. 2015. Macrophages and iron trafficking at the birth and death of red cells. Blood 125:2893
    • (2015) Blood , vol.125 , pp. 2893
    • Korolnek, T.1    Hamza, I.2
  • 10
    • 25844499787 scopus 로고    scopus 로고
    • A physiological model to study iron recycling in macrophages
    • Delabya, C., Pilarda, N., Hetetb, G. et al. 2005. A physiological model to study iron recycling in macrophages. Exp. Cell Res. 310:43
    • (2005) Exp. Cell Res , vol.310 , pp. 43
    • Delabya, C.1    Pilarda, N.2    Hetetb, G.3
  • 11
    • 0024501951 scopus 로고
    • Cachectin/ tumor necrosis factor-alpha alters red blood cell kinetics and induces anemia in vivo
    • Moldawer, L. L., Marano, M. A., Wei, H. et al. 1989. Cachectin/ tumor necrosis factor-alpha alters red blood cell kinetics and induces anemia in vivo. FASEB J. 3:1637
    • (1989) FASEB J , vol.3 , pp. 1637
    • Moldawer, L.L.1    Marano, M.A.2    Wei, H.3
  • 12
    • 84966365386 scopus 로고    scopus 로고
    • Inflammationassociated changes in lipid composition and the organization of the erythrocyte membrane
    • Dinkla, S., van Eijk, L. T., Fuchs, B. et al. 2016. Inflammationassociated changes in lipid composition and the organization of the erythrocyte membrane. BBA Clin. 5:186
    • (2016) BBA Clin , vol.5 , pp. 186
    • Dinkla, S.1    van Eijk, L.T.2    Fuchs, B.3
  • 13
    • 0043132448 scopus 로고    scopus 로고
    • Alterations of red blood cell shape and sialic acid membrane content in septic patients
    • Piagnerelli, K., Boudjeltia, M., Brohee, D. et al. 2003. Alterations of red blood cell shape and sialic acid membrane content in septic patients. Crit. Care Med. 31:2156
    • (2003) Crit. Care Med , vol.31 , pp. 2156
    • Piagnerelli, K.1    Boudjeltia, M.2    Brohee, D.3
  • 14
    • 0028953796 scopus 로고
    • Effect of sepsis on erythrocyte intracellular calcium homeostasis
    • Todd, J. C. 3rd and Mollitt, D. L. 1995. Effect of sepsis on erythrocyte intracellular calcium homeostasis. Crit. Care Med. 23:459
    • (1995) Crit. Care Med , vol.23 , pp. 459
    • Todd, J.C.1    Mollitt, D.L.2
  • 17
    • 33750451990 scopus 로고    scopus 로고
    • Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin
    • Schaer, C. A., Schoedon, G., Imhof, A., Kurrer, M. O. and Schaer, D. J. 2006. Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin. Circ. Res. 99:943
    • (2006) Circ. Res , vol.99 , pp. 943
    • Schaer, C.A.1    Schoedon, G.2    Imhof, A.3    Kurrer, M.O.4    Schaer, D.J.5
  • 18
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • Tenhunen, R., Marver, H. S. and Schmid, R. 1968. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl Acad. Sci. USA 61:748
    • (1968) Proc. Natl Acad. Sci. USA , vol.61 , pp. 748
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 19
    • 40349103525 scopus 로고    scopus 로고
    • Macrophages function as a ferritin iron source for cultured human erythroid precursors
    • Leimberg, M. J., Prus, E., Konijn, A. M. and Fibach, E. 2008. Macrophages function as a ferritin iron source for cultured human erythroid precursors. J. Cell. Biochem. 103:1211
    • (2008) J. Cell. Biochem , vol.103 , pp. 1211
    • Leimberg, M.J.1    Prus, E.2    Konijn, A.M.3    Fibach, E.4
  • 20
    • 20444416123 scopus 로고    scopus 로고
    • The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
    • Donovan, A., Lima, C. A., Pinkus, J. L. et al. 2005. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 1:191
    • (2005) Cell Metab , vol.1 , pp. 191
    • Donovan, A.1    Lima, C.A.2    Pinkus, J.L.3
  • 21
    • 84983748392 scopus 로고    scopus 로고
    • The repair of skeletal muscle requires iron recycling through macrophage ferroportin
    • Corna, G., Caserta, I., Monno, A. et al. 2016. The repair of skeletal muscle requires iron recycling through macrophage ferroportin. J. Immunol. 197:1914
    • (2016) J. Immunol , vol.197 , pp. 1914
    • Corna, G.1    Caserta, I.2    Monno, A.3
  • 22
    • 0037093202 scopus 로고    scopus 로고
    • Regulation of ferritin genes and protein
    • Torti, F. M. and Torti, S. V. 2002. Regulation of ferritin genes and protein. Blood 99:3505
    • (2002) Blood , vol.99 , pp. 3505
    • Torti, F.M.1    Torti, S.V.2
  • 23
    • 84962074006 scopus 로고    scopus 로고
    • Association of multiple biomarkers of iron metabolism and type 2 diabetes: The EPIC-InterAct Study
    • Podmore, C., Meidtner, K., Schulze, M. B. et al. 2016. Association of multiple biomarkers of iron metabolism and type 2 diabetes: The EPIC-InterAct Study. Diabetes Care 39:572
    • (2016) Diabetes Care , vol.39 , pp. 572
    • Podmore, C.1    Meidtner, K.2    Schulze, M.B.3
  • 25
    • 85010366264 scopus 로고    scopus 로고
    • Ferritin levels and risk of heart failure-the Atherosclerosis Risk in Communities Study
    • Silvestre, O. M., Gonçalves, A., Nadruz, W. Jr et al. 2017. Ferritin levels and risk of heart failure-the Atherosclerosis Risk in Communities Study. Eur. J. Heart Fail. 19:340
    • (2017) Eur. J. Heart Fail , vol.19 , pp. 340
    • Silvestre, O.M.1    Gonçalves, A.2    Nadruz, W.3
  • 27
    • 0027435537 scopus 로고
    • Iron uptake mechanisms of pathogenic bacteria
    • Wooldridge, K. G. and Williams, P. H. 1993. Iron uptake mechanisms of pathogenic bacteria. FEMS Microbiol. Rev. 12:325
    • (1993) FEMS Microbiol. Rev , vol.12 , pp. 325
    • Wooldridge, K.G.1    Williams, P.H.2
  • 28
    • 0021341476 scopus 로고
    • Mechanism of impaired iron release by the reticuloendothelial system during the hypoferremic phase of experimental Neisseria meningitidis infection in mice
    • Letendre, E. D. and Holbein, B. E. 1984. Mechanism of impaired iron release by the reticuloendothelial system during the hypoferremic phase of experimental Neisseria meningitidis infection in mice. Infect. Immun. 44:320
    • (1984) Infect. Immun , vol.44 , pp. 320
    • Letendre, E.D.1    Holbein, B.E.2
  • 29
    • 84962591966 scopus 로고    scopus 로고
    • Effect of iron/folic Acid supplementation on the outcome of malaria episodes treated with sulfadoxine-pyrimethamine
    • Sazawal, S., Black, R. E., Kabole, I., Dutta, A., Dhingra, U. and Ramsan, M. 2014. Effect of iron/folic Acid supplementation on the outcome of malaria episodes treated with sulfadoxine-pyrimethamine. Malar. Res. Treat. 2014:625905
    • (2014) Malar. Res. Treat , vol.2014
    • Sazawal, S.1    Black, R.E.2    Kabole, I.3    Dutta, A.4    Dhingra, U.5    Ramsan, M.6
  • 30
    • 0027311013 scopus 로고
    • Etiology of hypoferremia in a recently sedentary Kalahari village
    • Kent, S. and Dunn, D. 1993. Etiology of hypoferremia in a recently sedentary Kalahari village. Am. J. Trop. Med. Hyg. 48:554
    • (1993) Am. J. Trop. Med. Hyg , vol.48 , pp. 554
    • Kent, S.1    Dunn, D.2
  • 31
    • 0024431912 scopus 로고
    • Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor
    • Alvarez-Hernández, X., Licéaga, J., McKay, I. C. and Brock, J. H. 1989. Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor. Lab. Invest. 61:319
    • (1989) Lab. Invest , vol.61 , pp. 319
    • Alvarez-Hernández, X.1    Licéaga, J.2    McKay, I.C.3    Brock, J.H.4
  • 32
    • 78149250305 scopus 로고    scopus 로고
    • Polarization dictates iron handling by inflammatory and alternatively activated macrophages
    • Corna, G., Campana, L., Pignatti, E. et al. 2010. Polarization dictates iron handling by inflammatory and alternatively activated macrophages. Haematologica 95:1814
    • (2010) Haematologica , vol.95 , pp. 1814
    • Corna, G.1    Campana, L.2    Pignatti, E.3
  • 33
    • 77749260592 scopus 로고    scopus 로고
    • Differential regulation of iron homeostasis during human macrophage polarized activation
    • Recalcati, S., Locati, M., Marini, A. et al. 2010. Differential regulation of iron homeostasis during human macrophage polarized activation. Eur. J. Immunol. 40:824
    • (2010) Eur. J. Immunol , vol.40 , pp. 824
    • Recalcati, S.1    Locati, M.2    Marini, A.3
  • 34
    • 52749097757 scopus 로고    scopus 로고
    • Effects of the Aspergillus fumigatus siderophore systems on the regulation of macrophage immune effector pathways and iron homeostasis
    • Seifert, M., Nairz, M., Schroll, A., Schrettl, M., Haas, H. and Weiss, G. 2008. Effects of the Aspergillus fumigatus siderophore systems on the regulation of macrophage immune effector pathways and iron homeostasis. Immunobiology 213:767
    • (2008) Immunobiology , vol.213 , pp. 767
    • Seifert, M.1    Nairz, M.2    Schroll, A.3    Schrettl, M.4    Haas, H.5    Weiss, G.6
  • 35
    • 0019439290 scopus 로고
    • Ferritin synthesis in inflammation. II. Mechanism of increased ferritin synthesis
    • Konijn, A. M., Carmel, N., Levy, R. and Hershko, C. 1981. Ferritin synthesis in inflammation. II. Mechanism of increased ferritin synthesis. Br. J. Haematol. 49:361
    • (1981) Br. J. Haematol , vol.49 , pp. 361
    • Konijn, A.M.1    Carmel, N.2    Levy, R.3    Hershko, C.4
  • 36
    • 38049054790 scopus 로고    scopus 로고
    • New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity
    • Recalcati, S., Invernizzi, P., Arosio, P. and Cairo, G. 2008. New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. J. Autoimmun. 30:84
    • (2008) J. Autoimmun , vol.30 , pp. 84
    • Recalcati, S.1    Invernizzi, P.2    Arosio, P.3    Cairo, G.4
  • 37
    • 0028981059 scopus 로고
    • Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha
    • Kwak, E. L., Larochelle, D. A., Beaumont, C., Torti, S. V. and Torti, F. M. 1995. Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha. J. Biol. Chem. 270:15285
    • (1995) J. Biol. Chem , vol.270 , pp. 15285
    • Kwak, E.L.1    Larochelle, D.A.2    Beaumont, C.3    Torti, S.V.4    Torti, F.M.5
  • 38
    • 8344260568 scopus 로고    scopus 로고
    • Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species
    • Pham, C. G., Bubici, C., Zazzeroni, F. et al. 2004. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell 119:529
    • (2004) Cell , vol.119 , pp. 529
    • Pham, C.G.1    Bubici, C.2    Zazzeroni, F.3
  • 40
    • 0028302350 scopus 로고
    • Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsive element
    • Rogers, J. T., Andriotakis, J. L., Lacroix, L., Durmowicz, G. P., Kasschau, K. D. and Bridges, K. R. 1994. Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsive element. Nucleic Acids Res. 22:2678
    • (1994) Nucleic Acids Res , vol.22 , pp. 2678
    • Rogers, J.T.1    Andriotakis, J.L.2    Lacroix, L.3    Durmowicz, G.P.4    Kasschau, K.D.5    Bridges, K.R.6
  • 41
    • 84949116029 scopus 로고    scopus 로고
    • Distinct regulatory mechanisms of the human ferritin gene by hypoxia and hypoxia mimetic cobalt chloride at the transcriptional and post-transcriptional levels
    • Huang, B. W., Miyazawa, M. and Tsuji, Y. 2014. Distinct regulatory mechanisms of the human ferritin gene by hypoxia and hypoxia mimetic cobalt chloride at the transcriptional and post-transcriptional levels. Cell Signal. 26:2702
    • (2014) Cell Signal , vol.26 , pp. 2702
    • Huang, B.W.1    Miyazawa, M.2    Tsuji, Y.3
  • 42
    • 0031454793 scopus 로고    scopus 로고
    • Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron
    • Tran, T. N., Eubanks, S. K., Schaffer, K. J., Zhou, C. Y. and Linder, M. C. 1997. Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. Blood 90:4979
    • (1997) Blood , vol.90 , pp. 4979
    • Tran, T.N.1    Eubanks, S.K.2    Schaffer, K.J.3    Zhou, C.Y.4    Linder, M.C.5
  • 43
    • 0019835872 scopus 로고
    • Detection of a glycosylated subunit in human serum ferritin
    • Cragg, S. J., Wagstaff, M. and Worwood, M. 1981. Detection of a glycosylated subunit in human serum ferritin. Biochem. J. 199:565
    • (1981) Biochem. J , vol.199 , pp. 565
    • Cragg, S.J.1    Wagstaff, M.2    Worwood, M.3
  • 44
    • 1542373644 scopus 로고    scopus 로고
    • Regulated secretion of glycosylated human ferritin from hepatocytes
    • Ghosh, S., Hevi, S. and Chuck, S. L. 2004. Regulated secretion of glycosylated human ferritin from hepatocytes. Blood 103:2369
    • (2004) Blood , vol.103 , pp. 2369
    • Ghosh, S.1    Hevi, S.2    Chuck, S.L.3
  • 45
    • 85034241005 scopus 로고    scopus 로고
    • Diagnostic value of and glycosylated ferritin in adult onset Still's disease
    • Fautrel, B., Moël, G., Saint-Marcoux, B. et al. 2001. Diagnostic value of and glycosylated ferritin in adult onset Still's disease. J. Rheumatol. 28:12
    • (2001) J. Rheumatol , vol.28 , pp. 12
    • Fautrel, B.1    Moël, G.2    Saint-Marcoux, B.3
  • 47
    • 0028246898 scopus 로고
    • Serum ferritin and isoferritins are tools for diagnosis of active adult Still's disease
    • Van Reeth, C. Le Moel, G., Lasne, Y. et al. 1994. Serum ferritin and isoferritins are tools for diagnosis of active adult Still's disease. J. Rheumatol. 21:890
    • (1994) J. Rheumatol , vol.21 , pp. 890
    • Van Reeth, C.1    Le Moel, G.2    Lasne, Y.3
  • 48
    • 0029092843 scopus 로고    scopus 로고
    • Biochemical analysis of ferritin subunits in sera from adult Still's disease patients
    • Higashi, S., Ota, T. and Eto, S. Biochemical analysis of ferritin subunits in sera from adult Still's disease patients. Rheumatol Int. 15:45
    • Rheumatol Int , vol.15 , pp. 45
    • Higashi, S.1    Ota, T.2    Eto, S.3
  • 49
    • 0031571234 scopus 로고    scopus 로고
    • Hyperferritinemia in Still syndrome in the adult and reactive hemophagocytic syndrome
    • Zollner, R. C., Kern, P., Steininger, H. et al. 1997. Hyperferritinemia in Still syndrome in the adult and reactive hemophagocytic syndrome. Med. Klin. (Munich) 92:494
    • (1997) Med. Klin. (Munich) , vol.92 , pp. 494
    • Zollner, R.C.1    Kern, P.2    Steininger, H.3
  • 50
    • 0038076171 scopus 로고    scopus 로고
    • High ferritin and low glycosylated ferritin may also be a marker of excessive macrophage activation
    • Lambotte, O., Cacoub, P., Costedoat, N. et al. 2003. High ferritin and low glycosylated ferritin may also be a marker of excessive macrophage activation. J. Rheumatol. 30:1027
    • (2003) J. Rheumatol , vol.30 , pp. 1027
    • Lambotte, O.1    Cacoub, P.2    Costedoat, N.3
  • 51
    • 69849098332 scopus 로고    scopus 로고
    • The early diagnosis and clinical analysis of 57 cases of acquired hemophagocytic lymphohistiocytosis
    • Wang, Z., Wang, Y. N., Feng, C. C., Tian, L. P. and Chen, X. 2009. The early diagnosis and clinical analysis of 57 cases of acquired hemophagocytic lymphohistiocytosis. Zhonghua Nei Ke Za Zhi 48:312
    • (2009) Zhonghua Nei Ke Za Zhi , vol.48 , pp. 312
    • Wang, Z.1    Wang, Y.N.2    Feng, C.C.3    Tian, L.P.4    Chen, X.5
  • 52
    • 66349097529 scopus 로고    scopus 로고
    • Druginduced hypersensitivity syndrome: clinical and biologic disease patterns in 24 patients
    • Benm'rad, M., Leclerc-Mercier, S., Blanche, P. et al. 2009. Druginduced hypersensitivity syndrome: clinical and biologic disease patterns in 24 patients. Medicine (Baltimore) 88:131
    • (2009) Medicine (Baltimore) , vol.88 , pp. 131
    • Benm'rad, M.1    Leclerc-Mercier, S.2    Blanche, P.3
  • 55
    • 0022545038 scopus 로고
    • Binding of serum ferritin to concanavalin A in patients with malignancy
    • Muylle, L., Blockx, P. and Becquart, D. 1986. Binding of serum ferritin to concanavalin A in patients with malignancy. Biomed. Pharmacother. 40:225
    • (1986) Biomed. Pharmacother , vol.40 , pp. 225
    • Muylle, L.1    Blockx, P.2    Becquart, D.3
  • 56
    • 0028488052 scopus 로고
    • The clinical significance of glycosylated ferritin in iron overloads and hematopoietic malignancies
    • Takakuwa, Y., Miyazawa, K., Yoshikawa, O. and Toyama, K. 1994. The clinical significance of glycosylated ferritin in iron overloads and hematopoietic malignancies. Rinsho Ketsueki 35:744
    • (1994) Rinsho Ketsueki , vol.35 , pp. 744
    • Takakuwa, Y.1    Miyazawa, K.2    Yoshikawa, O.3    Toyama, K.4
  • 57
    • 0034107077 scopus 로고    scopus 로고
    • Percentage of glycosylated serum ferritin remains low throughout the course of adult onset Still's disease
    • Vignes, S., Le Moël, G., Fautrel, B., Wechsler, B., Godeau, P. and Piette, J. C. 2000. Percentage of glycosylated serum ferritin remains low throughout the course of adult onset Still's disease. Ann. Rheum. Dis. 59:347
    • (2000) Ann. Rheum. Dis , vol.59 , pp. 347
    • Vignes, S.1    Le Moël, G.2    Fautrel, B.3    Wechsler, B.4    Godeau, P.5    Piette, J.C.6
  • 58
    • 67049136594 scopus 로고    scopus 로고
    • Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment
    • Fan, Y., Yamada, T., Shimizu, T. et al. 2009. Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment. Toxicol. Pathol. 37:209
    • (2009) Toxicol. Pathol , vol.37 , pp. 209
    • Fan, Y.1    Yamada, T.2    Shimizu, T.3
  • 59
    • 3042769328 scopus 로고    scopus 로고
    • Parenteral iron nephrotoxicity: potential mechanisms and consequences
    • Zager, R. A., Johnson, A. C. and Hanson, S. Y. 2004. Parenteral iron nephrotoxicity: potential mechanisms and consequences. Kidney Int. 66:144
    • (2004) Kidney Int , vol.66 , pp. 144
    • Zager, R.A.1    Johnson, A.C.2    Hanson, S.Y.3
  • 60
    • 0027989345 scopus 로고
    • Increased release of ferritin and iron by iron-loaded alveolar macrophages in cigarette smokers
    • Wesselius, L. J., Nelson, M. E. and Skikne, B. S. 1994. Increased release of ferritin and iron by iron-loaded alveolar macrophages in cigarette smokers. Am. J. Respir. Crit. Care Med. 150:690
    • (1994) Am. J. Respir. Crit. Care Med , vol.150 , pp. 690
    • Wesselius, L.J.1    Nelson, M.E.2    Skikne, B.S.3
  • 61
    • 60249084746 scopus 로고    scopus 로고
    • Cellautonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism
    • Ferring-Appel, D., Hentze, M. W. and Galy, B. 2009. Cellautonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism. Blood 113:679
    • (2009) Blood , vol.113 , pp. 679
    • Ferring-Appel, D.1    Hentze, M.W.2    Galy, B.3
  • 62
    • 0030811101 scopus 로고    scopus 로고
    • Hereditary hyperferritinemia-cataract syndrome: relationship between phenotypes and specific mutations in the iron-responsive element of ferritin light-chain mRNA
    • Cazzola, M., Bergamaschi, G., Tonon, L. et al. 1997. Hereditary hyperferritinemia-cataract syndrome: relationship between phenotypes and specific mutations in the iron-responsive element of ferritin light-chain mRNA. Blood 90:814
    • (1997) Blood , vol.90 , pp. 814
    • Cazzola, M.1    Bergamaschi, G.2    Tonon, L.3
  • 63
    • 84925491489 scopus 로고    scopus 로고
    • sCD163 in AOSD: a biomarker for macrophage activation related to hyperferritinemia
    • Colafrancesco, S., Priori, R., Alessandri, C. et al. 2014. sCD163 in AOSD: a biomarker for macrophage activation related to hyperferritinemia. Immunol. Res. 60:177
    • (2014) Immunol. Res , vol.60 , pp. 177
    • Colafrancesco, S.1    Priori, R.2    Alessandri, C.3
  • 64
    • 33749242775 scopus 로고    scopus 로고
    • Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsis
    • Schaer, D. J., Schaer, C. A., Schoedon, G., Imhof, A. and Kurrer, M. O. 2006. Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsis. Eur. J. Haematol. 77:432
    • (2006) Eur. J. Haematol , vol.77 , pp. 432
    • Schaer, D.J.1    Schaer, C.A.2    Schoedon, G.3    Imhof, A.4    Kurrer, M.O.5
  • 65
    • 63349103637 scopus 로고    scopus 로고
    • Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells
    • Ruddell, R. G., Hoang-Le, D., Barwood, J. M. et al. 2009. Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells. Hepatology 49:887
    • (2009) Hepatology , vol.49 , pp. 887
    • Ruddell, R.G.1    Hoang-Le, D.2    Barwood, J.M.3
  • 66
    • 77951673268 scopus 로고    scopus 로고
    • TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity
    • Freeman, G. J., Casasnovas, J. M., Umetsu, D. T. and DeKruyff, R. H. 2010. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol. Rev. 235:172
    • (2010) Immunol. Rev , vol.235 , pp. 172
    • Freeman, G.J.1    Casasnovas, J.M.2    Umetsu, D.T.3    DeKruyff, R.H.4
  • 67
    • 0026040435 scopus 로고
    • Specific binding sites for H-ferritin on human lymphocytes: modulation during cellular proliferation and potential implication in cell growth control
    • Fargion, S., Fracanzani, A. L., Brando, B., Arosio, P., Levi, S. and Fiorelli, G. 1991. Specific binding sites for H-ferritin on human lymphocytes: modulation during cellular proliferation and potential implication in cell growth control. Blood 78:1056
    • (1991) Blood , vol.78 , pp. 1056
    • Fargion, S.1    Fracanzani, A.L.2    Brando, B.3    Arosio, P.4    Levi, S.5    Fiorelli, G.6
  • 68
    • 0024496308 scopus 로고
    • Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis
    • Broxmeyer, H. E., Williams, D. E., Geissler, K. et al. 1989. Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis. Blood 73:74
    • (1989) Blood , vol.73 , pp. 74
    • Broxmeyer, H.E.1    Williams, D.E.2    Geissler, K.3
  • 69
    • 84891834200 scopus 로고    scopus 로고
    • Suppression of immunoglobulin production in human peripheral blood mononuclear cells by monocytes via secretion of heavychain ferritin
    • Yamashita, M., Harada, G., Matsumoto, S. E. et al. 2014. Suppression of immunoglobulin production in human peripheral blood mononuclear cells by monocytes via secretion of heavychain ferritin. Immunobiology 219:149
    • (2014) Immunobiology , vol.219 , pp. 149
    • Yamashita, M.1    Harada, G.2    Matsumoto, S.E.3
  • 70
    • 33845980588 scopus 로고    scopus 로고
    • Chemokine CXCL12 induces binding of ferritin heavy chain to the chemokine receptor CXCR4, alters CXCR4 signaling, and induces phosphorylation and nuclear translocation of ferritin heavy chain
    • Li, R., Luo, C., Mines, M., Zhang, J. and Fan, G. H. 2006. Chemokine CXCL12 induces binding of ferritin heavy chain to the chemokine receptor CXCR4, alters CXCR4 signaling, and induces phosphorylation and nuclear translocation of ferritin heavy chain. J. Biol. Chem. 281:37616
    • (2006) J. Biol. Chem , vol.281 , pp. 37616
    • Li, R.1    Luo, C.2    Mines, M.3    Zhang, J.4    Fan, G.H.5
  • 71
    • 0036565874 scopus 로고    scopus 로고
    • Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells
    • Gray, C. P., Arosio, P. and Hersey, P. 2002. Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells. Blood 99:3326
    • (2002) Blood , vol.99 , pp. 3326
    • Gray, C.P.1    Arosio, P.2    Hersey, P.3
  • 72
    • 0023280852 scopus 로고
    • Ferritin selectively suppresses delayed-type hypersensitivity responses at induction or effector phase
    • Harada, T., Baba, M., Torii, I. and Morikawa, S. 1987. Ferritin selectively suppresses delayed-type hypersensitivity responses at induction or effector phase. Cell. Immunol. 109:75
    • (1987) Cell. Immunol , vol.109 , pp. 75
    • Harada, T.1    Baba, M.2    Torii, I.3    Morikawa, S.4
  • 73
    • 0028905811 scopus 로고
    • Reversal of ferritin-mediated immunosuppression by levamisole: a rationale for its application to management of the acquired immune deficiency syndrome (AIDS)
    • Wigginton, J. M. 1995. Reversal of ferritin-mediated immunosuppression by levamisole: a rationale for its application to management of the acquired immune deficiency syndrome (AIDS). Med. Hypotheses 44:85
    • (1995) Med. Hypotheses , vol.44 , pp. 85
    • Wigginton, J.M.1
  • 74
    • 85003875704 scopus 로고    scopus 로고
    • A systemic inflammation mortality risk assessment contingency table for severe sepsis
    • Carcillo, J. A., Sward, K., Halstead, E.S. et al. 2016. A systemic inflammation mortality risk assessment contingency table for severe sepsis. Pediatr. Crit. Care Med. 18:143
    • (2016) Pediatr. Crit. Care Med , vol.18 , pp. 143
    • Carcillo, J.A.1    Sward, K.2    Halstead, E.S.3
  • 76
    • 81155135069 scopus 로고    scopus 로고
    • Very high serum ferritin levels are associated with increased mortality and critical care in pediatric patients
    • Bennett, T. D., Hayward, K. N., Farris, R. W., Ringold, S., Wallace, C. A. and Brogan, T. V. 2011. Very high serum ferritin levels are associated with increased mortality and critical care in pediatric patients. Pediatr. Crit. Care Med. 12:e233
    • (2011) Pediatr. Crit. Care Med , vol.12 , pp. e233
    • Bennett, T.D.1    Hayward, K.N.2    Farris, R.W.3    Ringold, S.4    Wallace, C.A.5    Brogan, T.V.6
  • 77
    • 85011350046 scopus 로고    scopus 로고
    • Cardiac dysfunction at echocardiogram and ferritin as early markers of severity in pediatric sepsis
    • Tonial, C. T., Garcia, P. C. R., Schweitzer, L. C. et al. 2017. Cardiac dysfunction at echocardiogram and ferritin as early markers of severity in pediatric sepsis. J. Pediatr. (Rio J.) S0021-7557:30032
    • (2017) J. Pediatr. (Rio J.)
    • Tonial, C.T.1    Garcia, P.C.R.2    Schweitzer, L.C.3
  • 78
    • 68849131525 scopus 로고    scopus 로고
    • Secondary hemophagocytic lymphohistiocytosis and severe sepsis/ systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation
    • Castillo, L. and Carcillo, J. 2009. Secondary hemophagocytic lymphohistiocytosis and severe sepsis/ systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation. Pediatr. Crit. Care Med. 10:387
    • (2009) Pediatr. Crit. Care Med , vol.10 , pp. 387
    • Castillo, L.1    Carcillo, J.2
  • 79
    • 84887108546 scopus 로고    scopus 로고
    • The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome
    • Rosário, C., Zandman-Goddard, G., Meyron-Holtz, E. G., D'Cruz, D. P. and Shoenfeld, Y. 2013. The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome. BMC Med. 11:185
    • (2013) BMC Med , vol.11 , pp. 185
    • Rosário, C.1    Zandman-Goddard, G.2    Meyron-Holtz, E.G.3    D'Cruz, D.P.4    Shoenfeld, Y.5
  • 82
    • 29944442846 scopus 로고    scopus 로고
    • Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A
    • Zur Stadt, U., Beutel, K., Kolberg, S. et al. 2006. Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A. Hum. Mutat. 27:62
    • (2006) Hum. Mutat , vol.27 , pp. 62
    • Zur Stadt, U.1    Beutel, K.2    Kolberg, S.3
  • 83
    • 39549100377 scopus 로고    scopus 로고
    • Macrophage activation syndrome in rheumatic disease: what is the role of the antigen presenting cell? Autoimmun
    • Behrens, E. M. 2008. Macrophage activation syndrome in rheumatic disease: what is the role of the antigen presenting cell? Autoimmun. Rev. 7:305
    • (2008) Rev , vol.7 , pp. 305
    • Behrens, E.M.1
  • 84
    • 51249099119 scopus 로고    scopus 로고
    • Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome
    • Tang, Y., Xu, X., Song, H. et al. 2008. Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome. Br. J. Haematol. 143:84
    • (2008) Br. J. Haematol , vol.143 , pp. 84
    • Tang, Y.1    Xu, X.2    Song, H.3
  • 85
    • 0028177849 scopus 로고
    • Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults
    • Akashi, K., Hayashi, S., Gondo, H. et al. 1994. Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults. Br. J. Haematol. 87:243
    • (1994) Br. J. Haematol , vol.87 , pp. 243
    • Akashi, K.1    Hayashi, S.2    Gondo, H.3
  • 87
    • 84960470393 scopus 로고    scopus 로고
    • Macrophage activation syndrome
    • In Petty, R. E., Laxer, R. M., Lindsley, C. B. and Wedderburn, L., eds, Elsevier Inc., Philadelphia, PA
    • Grom A. A. 2016. Macrophage activation syndrome. In Petty, R. E., Laxer, R. M., Lindsley, C. B. and Wedderburn, L., eds, Textbook of Pediatric Rheumatology, p. 642, Elsevier Inc., Philadelphia, PA
    • (2016) Textbook of Pediatric Rheumatology , pp. 642
    • Grom, A.A.1
  • 88
    • 82155184541 scopus 로고    scopus 로고
    • Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH
    • Zhang, K., Jordan, M. B., Marsh, R. A. et al. 2011. Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH. Blood 118:5794
    • (2011) Blood , vol.118 , pp. 5794
    • Zhang, K.1    Jordan, M.B.2    Marsh, R.A.3
  • 89
    • 84953635379 scopus 로고    scopus 로고
    • Genetic predisposition to hemophagocytic lymphohistiocytosis: report on 500 patients from the Italian registry
    • Cetica, V., Sieni, E., Pende, D. et al. 2016. Genetic predisposition to hemophagocytic lymphohistiocytosis: report on 500 patients from the Italian registry. J. Allergy Clin. Immunol. 137:188
    • (2016) J. Allergy Clin. Immunol , vol.137 , pp. 188
    • Cetica, V.1    Sieni, E.2    Pende, D.3
  • 90
    • 85034265754 scopus 로고    scopus 로고
    • Genetic variants associated with hyperinflammation in septic shock
    • Kernan, K., Ghaloul-Gonzalez, L., Sethi, R. et al. 2016. Genetic variants associated with hyperinflammation in septic shock. Crit. Care Med. 44:427
    • (2016) Crit. Care Med , vol.44 , pp. 427
    • Kernan, K.1    Ghaloul-Gonzalez, L.2    Sethi, R.3
  • 91
    • 79957889288 scopus 로고    scopus 로고
    • Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice
    • Behrens, E. M., Canna, S. W., Slade, K. et al. 2011. Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice. J. Clin. Invest. 121:2264
    • (2011) J. Clin. Invest , vol.121 , pp. 2264
    • Behrens, E.M.1    Canna, S.W.2    Slade, K.3
  • 92
    • 33750479356 scopus 로고    scopus 로고
    • A critical role of CpG motifs in a murine peritonitis model by their binding to highly expressed toll-like receptor-9 on liver NKT cells
    • Tsujimoto, H., Ono, S., Matsumoto, A. et al. 2006. A critical role of CpG motifs in a murine peritonitis model by their binding to highly expressed toll-like receptor-9 on liver NKT cells. J. Hepatol. 45:836
    • (2006) J. Hepatol , vol.45 , pp. 836
    • Tsujimoto, H.1    Ono, S.2    Matsumoto, A.3
  • 93
    • 79251600358 scopus 로고    scopus 로고
    • Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice
    • Petrasek, J., Dolganiuc, A., Csak, T., Kurt-Jones, E. A. and Szabo, G. 2011. Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology 140:697
    • (2011) Gastroenterology , vol.140 , pp. 697
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Kurt-Jones, E.A.4    Szabo, G.5
  • 94
    • 40449097257 scopus 로고    scopus 로고
    • The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
    • Muruve, D. A., Pétrilli, V., Zaiss, A. K. et al. 2008. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452:103
    • (2008) Nature , vol.452 , pp. 103
    • Muruve, D.A.1    Pétrilli, V.2    Zaiss, A.K.3
  • 95
    • 85034259598 scopus 로고    scopus 로고
    • Toll-likereceptor expression and cellular immune reconstitution in AMLpatients with elevated serum ferritin levels after allogeneic transplant
    • Elmaagacli, A., Steckel, N., Koldehoff, M. et al. 2010. Toll-likereceptor expression and cellular immune reconstitution in AMLpatients with elevated serum ferritin levels after allogeneic transplant. Blood 116:1049
    • (2010) Blood , vol.116 , pp. 1049
    • Elmaagacli, A.1    Steckel, N.2    Koldehoff, M.3
  • 96
    • 84954310841 scopus 로고    scopus 로고
    • Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome: reanalysis of a prior phase III trial
    • Shakoory, B., Carcillo, J. A., Chatham, W. W. et al. 2016. Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome: reanalysis of a prior phase III trial. Crit. Care Med. 44:275
    • (2016) Crit. Care Med , vol.44 , pp. 275
    • Shakoory, B.1    Carcillo, J.A.2    Chatham, W.W.3
  • 97
    • 70449727077 scopus 로고    scopus 로고
    • Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
    • Lamkanfi, M., Mueller, J. L., Vitari, A. C. et al. 2009. Glyburide inhibits the Cryopyrin/Nalp3 inflammasome. J. Cell Biol. 187:61
    • (2009) J. Cell Biol , vol.187 , pp. 61
    • Lamkanfi, M.1    Mueller, J.L.2    Vitari, A.C.3
  • 98
    • 84924415042 scopus 로고    scopus 로고
    • A smallmolecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
    • Coll, R. C., Robertson, A. A., Chae, J. J. et al. 2015. A smallmolecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat. Med. 21:248
    • (2015) Nat. Med , vol.21 , pp. 248
    • Coll, R.C.1    Robertson, A.A.2    Chae, J.J.3
  • 99
    • 84899943272 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: clinical analysis of 103 adult patients
    • Li, J., Wang, Q., Zheng, W. et al. 2014. Hemophagocytic lymphohistiocytosis: clinical analysis of 103 adult patients. Medicine (Baltimore) 93:100
    • (2014) Medicine (Baltimore) , vol.93 , pp. 100
    • Li, J.1    Wang, Q.2    Zheng, W.3
  • 100
    • 84908383447 scopus 로고    scopus 로고
    • Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    • Davì, S., Minoia, F., Pistorio, A. et al.; Paediatric Rheumatology International Trials Organisation, the Childhood Arthritis and Rheumatology Research Alliance, the Pediatric Rheumatology Collaborative Study Group, and the Histiocyte Society. 2014. Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Arthritis Rheumatol. 66:2871
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2871
    • Davì, S.1    Minoia, F.2    Pistorio, A.3
  • 101
    • 84949200612 scopus 로고    scopus 로고
    • Evidence-based diagnosis and treatment of macrophage activation syndrome in systemic juvenile idiopathic arthritis
    • Boom, V., Anton, J., Lahdenne, P. et al. 2015. Evidence-based diagnosis and treatment of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Pediatr. Rheumatol. Online J. 13:55
    • (2015) Pediatr. Rheumatol. Online J , vol.13 , pp. 55
    • Boom, V.1    Anton, J.2    Lahdenne, P.3
  • 102
    • 33845619137 scopus 로고    scopus 로고
    • HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis
    • Henter, J. I., Horne, A., Aricó, M. et al. 2007. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr. Blood Cancer 48:124
    • (2007) Pediatr. Blood Cancer , vol.48 , pp. 124
    • Henter, J.I.1    Horne, A.2    Aricó, M.3
  • 103
    • 85008350887 scopus 로고    scopus 로고
    • Secondary hemophagocytic lymphohistiocytosis: do we really need chemotherapeutics for all patients?
    • Haytoglu, Z., Yazici, N. and Erbay, A. 2017. Secondary hemophagocytic lymphohistiocytosis: do we really need chemotherapeutics for all patients? J. Pediatr. Hematol. Oncol. 39:e106
    • (2017) J. Pediatr. Hematol. Oncol , vol.39 , pp. e106
    • Haytoglu, Z.1    Yazici, N.2    Erbay, A.3
  • 104
    • 84860261913 scopus 로고    scopus 로고
    • Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/ sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment? Crit
    • Demirkol, D., Yildizdas, D., Bayrakci, B. et al.; Turkish Secondary HLH/MAS Critical Care Study Group. 2012. Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/ sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment? Crit. Care 16:R52
    • (2012) Care , vol.16 , pp. R52
    • Demirkol, D.1    Yildizdas, D.2    Bayrakci, B.3
  • 105
    • 67349130863 scopus 로고    scopus 로고
    • Macrophage activation syndrome: serological markers and treatment with anti-thymocyte globulin
    • Coca, A., Bundy, K. W., Marston, B., Huggins, J. and Looney, R. J. 2009. Macrophage activation syndrome: serological markers and treatment with anti-thymocyte globulin. Clin. Immunol. 132:10
    • (2009) Clin. Immunol , vol.132 , pp. 10
    • Coca, A.1    Bundy, K.W.2    Marston, B.3    Huggins, J.4    Looney, R.J.5
  • 106
    • 85011394802 scopus 로고    scopus 로고
    • How to treat involvement of the central nervous system in hemophagocytic lymphohistiocytosis? Curr
    • Horne, A., Wickström, R., Jordan, M. B. et al. 2017. How to treat involvement of the central nervous system in hemophagocytic lymphohistiocytosis? Curr. Treat. Options Neurol. 19:3
    • (2017) Treat. Options Neurol , vol.19 , pp. 3
    • Horne, A.1    Wickström, R.2    Jordan, M.B.3
  • 108
    • 85008220560 scopus 로고    scopus 로고
    • Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition
    • Canna, S. W., Girard, C., Malle, L. et al. 2017. Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition. J. Allergy Clin. Immunol. 139:1698
    • (2017) J. Allergy Clin. Immunol , vol.139 , pp. 1698
    • Canna, S.W.1    Girard, C.2    Malle, L.3


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