Ferritin expression in rat hepatocytes and kupffer cells after lead nitrate treatment

Toxicologic Pathology

Volumn 37, Issue 2, 2009, Pages 209-217

  Fan, Yang ^a,d   Yamada, Toshiyuki ^a   Shimizu, Takeshi ^a   Nanashima, Naoki ^a,b   Akita, Miki ^a   Suto, Kohji ^c   Tsuchida, Shigeki ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

^c Hirosaki City Hospital   (Japan)

^d CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell proliferation; Ferritin; Kupffer cell; Lead nitrate; Phagocytosis

Indexed keywords

CLOFIBRATE; FERRITIN; LACTADHERIN; LEAD NITRATE; LEAD; LEUKOCYTE ANTIGEN; NITRATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CENTRAL VEIN; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; KUPFFER CELL; LIVER CELL; MALE; NICK END LABELING; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING; ANIMAL; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANTIGENS, CD; APOPTOSIS; CELL PROLIFERATION; FERRITINS; GENE EXPRESSION; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; KUPFFER CELLS; LEAD; MALE; NITRATES; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 67049136594     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623308328544     Document Type: Article

References (39)

1. Cairo, G, L Tacchini, G Pogliaghi, E Anzon, A Tomasi, and A Bernelli-Zazzera (1995). Induction of ferritin synthesis by oxidative stress. Transcriptional and post-transcriptional regulation by expansion of the "free" iron pool. J Biol Chem, 270, 700-3.
2. Callahan, MK, P Williamson, and RA Schlegel (2000). Surface expression of phosphatidylserine on macrophages is required for phagocytosis of apoptotic thymocytes. Cell Death Differ, 7, 645-53.
3. Columbano, A, and H Shinozuka (1996). Liver regeneration versus direct hyperplasia. FASEB J, 10, 1118-28.
4. Columbano, A, GM Ledda, P Sirigu, T Perra, and P Pani (1983). Liver cell proliferation induced by a single dose of lead nitrate. Am J Pathol, 110, 83-88. (Pubitemid 13170316)
5. Columbano, A, GM Ledda-Columbano, PP Coni, G Faa, C Liguori, G Santa Cruz, and P Pani (1985). Occurrence of cell death (apoptosis) during the involution of liver hyperplasia. Lab Invest, 52, 670-75.
6. Coni, P, G Simbula, AC de Prati, M Menegazzi, H Suzuki, DS Sarma, GM Ledda-Columbano, and A Columbano (1993). Differences in the steady-state level of c-fos, c-jun and c-myc messenger RNA during mitogen-induced liver growth and compensatory regeneration. Hepatology, 17, 1109-16.
7. Cozzi, A, S Levi, B Corsi, P Santambrogio, A Campanella, G Gerardi, and P Arosio (2003). Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells. FEBS Lett, 537, 187-92.
8. Cozzi, A, B Corsi, S Levi, P Santambrogio, G Biasiotto, and P Arosio (2004). Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin. Blood, 103, 2377-83.
9. Dignam, JD, RM Lebovitz, and RG Roeder (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res, 11, 1475-89.
10. Dini, L, MT Ruzittu, and L Falasca (1996). Recognition and phagocytosis of apoptotic cells. Scanning Microsc, 10, 239-51.
11. Dini, L, P Pagliara, and EC Carla (2002). Phagocytosis of apoptotic cells by liver: a morphological study. Microscopic Res Techniq, 57, 530-40.
12. Hanayama, R, M Tanaka, K Miyasaka, K Aozasa, Y Uchiyama, and S Nagata (2004). Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science, 304, 1147-50.
13. Harrison, PM, and P Arosio (1996). The ferritin: molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta, 1275, 161-203.
14. Hsu, S, L Raine, and H Fanger (1981). Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques. J Histochem Cytochem, 29, 577-80.
15. Ishikawa, H, M Kato, H Hori, K Ishimori, T Kirisato, F Tokunaga, and K Iwai (2005). Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2. Mol Cell, 19, 171-81.
16. Jover, R, RL Lindberg, and UA Meyer (1996). Role of heme in cyto-chrome P450 transcription and function in mice treated with lead acetate. J Phamacol Exp Ther, 50, 474-81.
17. Kikyo, N, M Suda, N Kikyo, K Hagiwara, K Yasukawa, Y Yazaki, and T Okabe (1994). Purification and characterization of a cell growth factor from a human leukemia cell line: immunological identity with ferritin. Cancer Res, 54, 268-71.
18. Klausner, RD, and JB Harford (1989). Cis-trans models for post-transcriptional gene regulation. Science, 246, 870-72.
19. Konijn, AM, N Carmel, R Levy, and C Hershko (1981). Ferritin synthesis in inflammation. II. Mechanism of increased ferritin synthesis. Br J Haematol, 49, 361-70.
20. Laemmli, UK (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Natrue, 227, 680-85.
21. Lawton, LJ, and WE Donaldson (1991). Lead-induced tissue fatty acid alterations and lipid peroxidation. Biol Trace Elem Res, 28, 83-97.
22. Leibold, EA, and HN Munro (1988). Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy and light-subunit mRNAs. Proc Natl Acad Sci USA, 85, 2171-75.
23. Milosevic, N, and P Maier (2000). Lead stimulates intercellular signalling between hepatocytes and Kupffer cells. Eur J Pharmacol, 401, 317-28.
24. Moore, MR, A Goldberg, and AA Yeung-Laiwah (1987). Lead effects on the heme biosynthetic pathway. Relationship to toxicity. Ann N Y Acad Sci, 514, 191-203.
25. Needleman, HL, and PJ Landrigan (1981). The health effects of low level exposure to lead. Annu Rev Public Health, 2, 277-98.
26. Nemeth, E, MS Tuttle, J Powelson, MB Vaughn, A Donovan, DM Ward, T Ganz, and J Kaplan (2004). Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science, 306, 2090-93.
27. Ookawa, K, T Kudo, S Aizawa, H Saito, and S Tsuchida (2002). Transcriptional activation of the MUC2 gene by p53. J Biol Chem, 277, 48270-75.
28. Otogawa, K, K Kinoshita, H Fujii, M Sakabe, R Shiga, K Nakatani, K Ikeda, Y Nakajima, Y Ikura, M Ueda, T Arakawa, F Hato, and N Kawada (2007). Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human non-alcoholic steatohepatitis. Am J Pathol, 170, 967-80.
29. Pagliara, P, EC Carlà, S Caforio, A Chionna, S Massa, L Abbro, and L Dini (2003). Kupffer cells promote lead nitrate-induced hepatocyte apoptosis via oxidative stress. Comp Hepatol, 2, 8.
30. Pigeon, C, G Ilyin, B Courselaud, P Leroyer, B Turlin, P Brissot, and O Loreal (2001). A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem, 276, 7811-19.
31. Roomi, MW, A Columbano, GM Ledda-Columbano, and DSR Sarma (1986). Lead nitrate induces certain biochemical properties characteristic of hepatocyte nodules. Carcinogenesis, 7, 1643-46.
32. Ruzittu, M, EC Carla, MR Montinari, G Maietta, and L Dini (1999). Modulation of cell surface expression of liver carbohydrate receptors during in vivo induction of apoptosis with lead nitrate. Cell Tissue Res, 298, 105-12.
33. Satoh, K, A Kitahara, and K Sato (1985). Identification of heterogeneous and microheterogeneous subunits of glutathione S-transferase in rat liver cytosol. Arch Biochem Biophys, 242, 104-11.
34. Savill, J, V Fadok, P Henson, and C Haslett (1993). Phagocyte recognition of cells undergoing apoptosis. Immunol Today, 14, 131-36.
35. Shinozuka, H, T Ohmura, SL Katyal, AI Zedda, GM Ledda-Columbano, and A Columbano (1996). Possible roles of nonparenchymal cells in hepatocyte proliferation induced by lead nitrate and by tumor necrosis factor alpha. Hepatology, 23, 1572-77.
36. Sleyster, E, and DL Knook (1982). Relation between localization and function of rat liver Kupffer cells. Lab Invest, 47, 484-90.
37. Towbin, H, T Staehelin, and J Gordon (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA, 76, 4350-54.
38. Waddell, BJ, S Hesheh, AM Dharmarajan, and PJ Burton (2000). Apoptosis in rat placenta is zone-dependent and stimulated by glucocor-ticoids. Biol Reprod, 63, 1913-17.
39. Yoshida, H, K Kawane, M Koike, Y Mori, Y Uchiyama, and S Nagata (2005). Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells. Nature, 437, 754-58.