-
1
-
-
77955508573
-
Hereditary hemochromatosis: Pathogenesis, diagnosis, and treatment
-
408.e1-2
-
Pietrangelo A. Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment. Gastro-enterology 2010;139:393-408, 408.e1-2
-
(2010)
Gastro-enterology
, vol.139
, pp. 393-408
-
-
Pietrangelo, A.1
-
2
-
-
84855977812
-
Pancreatic iron and glucose dysregulation in thalassemia major
-
Noetzli LJ, Mittelman SD, Watanabe RM, Coates TD, Wood JC. Pancreatic iron and glucose dysregulation in thalassemia major. Am J Hematol 2012;87:155-160
-
(2012)
Am J Hematol
, vol.87
, pp. 155-160
-
-
Noetzli, L.J.1
Mittelman, S.D.2
Watanabe, R.M.3
Coates, T.D.4
Wood, J.C.5
-
3
-
-
84877325970
-
Ferritin levels and risk of type 2 diabetes melli-tus: An updated systematic review and meta-analysis of prospective evidence
-
Kunutsor SK, Apekey TA, Walley J, Kain K. Ferritin levels and risk of type 2 diabetes melli-tus: an updated systematic review and meta-analysis of prospective evidence. Diabetes Metab Res Rev 2013;29:308-318
-
(2013)
Diabetes Metab Res Rev
, vol.29
, pp. 308-318
-
-
Kunutsor, S.K.1
Apekey, T.A.2
Walley, J.3
Kain, K.4
-
4
-
-
84903750950
-
Association of iron indices and type 2 diabetes: A meta-analysis of observational studies
-
Orban E, Schwab S, Thorand B, Huth C. Association of iron indices and type 2 diabetes: a meta-analysis of observational studies. Diabetes Metab Res Rev 2014;30:372-394
-
(2014)
Diabetes Metab Res Rev
, vol.30
, pp. 372-394
-
-
Orban, E.1
Schwab, S.2
Thorand, B.3
Huth, C.4
-
5
-
-
0015804314
-
Serum ferritin concentration and iron stores in normal subjects
-
Walters GO, Miller FM, Worwood M. Serum ferritin concentration and iron stores in normal subjects. J Clin Pathol 1973;26:770-772
-
(1973)
J Clin Pathol
, vol.26
, pp. 770-772
-
-
Walters, G.O.1
Miller, F.M.2
Worwood, M.3
-
6
-
-
84970822533
-
Ferritin in the serum of normal subjects and patients with iron deficiency and iron overload
-
Jacobs A, Miller F, Worwood M, Beamish MR, Wardrop CA. Ferritin in the serum of normal subjects and patients with iron deficiency and iron overload. BMJ 1972;4:206-208
-
(1972)
BMJ
, vol.4
, pp. 206-208
-
-
Jacobs, A.1
Miller, F.2
Worwood, M.3
Beamish, M.R.4
Wardrop, C.A.5
-
7
-
-
0036238428
-
Relationship of body iron stores to levels of serum fer-ritin, serum iron, unsaturated iron binding capacity and transferrin saturation in patients with iron storage disease
-
Beutler E, Felitti V, Ho NJ, Gelbart T. Relationship of body iron stores to levels of serum fer-ritin, serum iron, unsaturated iron binding capacity and transferrin saturation in patients with iron storage disease. Acta Haematol 2002;107:145-149
-
(2002)
Acta Haematol
, vol.107
, pp. 145-149
-
-
Beutler, E.1
Felitti, V.2
Ho, N.J.3
Gelbart, T.4
-
8
-
-
0642364499
-
Association of high serum ferritin concentration with glucose intolerance and insulin resistance in healthy people
-
Haap M, Fritsche A, Mensing HJ, Häring HU, Stumvoll M. Association of high serum ferritin concentration with glucose intolerance and insulin resistance in healthy people. Ann Intern Med. Ann Intern Med 2003;139:869-871
-
(2003)
Ann Intern Med. Ann Intern Med
, vol.139
, pp. 869-871
-
-
Haap, M.1
Fritsche, A.2
Mensing, H.J.3
Häring, H.U.4
Stumvoll, M.5
-
9
-
-
0025146396
-
Factors affecting the concentrations of ferritin in serum in a healthy Australian population
-
Leggett BA, Brown NN, Bryant SJ, Duplock L, Powell LW, Halliday JW. Factors affecting the concentrations of ferritin in serum in a healthy Australian population. Clin Chem 1990;36: 1350-1355
-
(1990)
Clin Chem
, vol.36
, pp. 1350-1355
-
-
Leggett, B.A.1
Brown, N.N.2
Bryant, S.J.3
Duplock, L.4
Powell, L.W.5
Halliday, J.W.6
-
10
-
-
84865120793
-
Dorothy Hodgkin Lecture 2012: Non-alcoholic fatty liver disease, insulin resistance and ectopic fat: A new problem in diabetes management
-
Byrne CD. Dorothy Hodgkin Lecture 2012: non-alcoholic fatty liver disease, insulin resistance and ectopic fat: a new problem in diabetes management. Diabet Med 2012;29: 1098-1107
-
(2012)
Diabet Med
, vol.29
, pp. 1098-1107
-
-
Byrne, C.D.1
-
12
-
-
0030997579
-
The laboratory assessment of iron status-an update
-
Worwood M. The laboratory assessment of iron status-an update.Clin Chim Acta 1997;259: 3-23
-
(1997)
Clin Chim Acta
, vol.259
, pp. 3-23
-
-
Worwood, M.1
-
13
-
-
84856292277
-
Iron overload in human disease
-
Fleming RE, Ponka P. Iron overload in human disease. N Engl J Med 2012;366:348-359
-
(2012)
N Engl J Med
, vol.366
, pp. 348-359
-
-
Fleming, R.E.1
Ponka, P.2
-
14
-
-
84857373097
-
Non-transferrin bound iron: A key role in iron overload and iron toxicity
-
Brissot P, Ropert M, LeLan C, Loréal O. Non-transferrin bound iron: a key role in iron overload and iron toxicity. Biochim Biophys Acta 2012;1820:403-410
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 403-410
-
-
Brissot, P.1
Ropert, M.2
LeLan, C.3
Loréal, O.4
-
15
-
-
80054698404
-
Design and cohort description of the InterAct Project:an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study
-
Langenberg C, Sharp S, Forouhi NG, et al.; InterAct Consortium. Design and cohort description of the InterAct Project:an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. Diabetologia 2011;54:2272-2282
-
(2011)
Diabetologia
, vol.54
, pp. 2272-2282
-
-
Langenberg, C.1
Sharp, S.2
Forouhi, N.G.3
-
16
-
-
84857916936
-
Validity of a short questionnaire to assess physical activity in 10 European countries
-
Peters T, Brage S, Westgate K, et al.; InterAct Consortium. Validity of a short questionnaire to assess physical activity in 10 European countries. Eur J Epidemiol 2012;27:15-25
-
(2012)
Eur J Epidemiol
, vol.27
, pp. 15-25
-
-
Peters, T.1
Brage, S.2
Westgate, K.3
-
17
-
-
84962088299
-
-
Westgard rules [Internet], 2009. Madison, WI, Westguard QC. Available from Accessed 25 January 2016
-
Westgard rules [Internet], 2009. Madison, WI, Westguard QC. Available from http://www .westgard.com/mltirule.htm. Accessed 25 January 2016
-
-
-
-
18
-
-
77953120762
-
EASL clinical practice guidelines for HFE hemochromatosis
-
European Association for the Study of the Liver. EASL clinical practice guidelines for HFE hemochromatosis. J Hepatol 2010;53:3-22
-
(2010)
J Hepatol
, vol.53
, pp. 3-22
-
-
-
19
-
-
77952529040
-
A position statement on NAFLD/NASH based on the EASL 2009 special conference
-
Ratziu V, Bellentani S, Cortez-Pinto H, Day C, Marchesini G. A position statement on NAFLD/NASH based on the EASL 2009 special conference. J Hepatol 2010;53:372-384
-
(2010)
J Hepatol
, vol.53
, pp. 372-384
-
-
Ratziu, V.1
Bellentani, S.2
Cortez-Pinto, H.3
Day, C.4
Marchesini, G.5
-
20
-
-
0029015738
-
Waist cir-cumferenceas a measure forindicating need for weight management
-
Lean ME, Han TS, Morrison CE. Waist cir-cumferenceas a measure forindicating need for weight management. BMJ 1995;311:158-161
-
(1995)
BMJ
, vol.311
, pp. 158-161
-
-
Lean, M.E.1
Han, T.S.2
Morrison, C.E.3
-
21
-
-
84884797324
-
Elevated serum ferritin level is associated with the incident type 2 diabetes in healthy Korean men: A 4 year longitudinal study
-
Jung CH, Lee MJ, Hwang JY, et al. Elevated serum ferritin level is associated with the incident type 2 diabetes in healthy Korean men: a 4 year longitudinal study. PLoS One 2013;8: e75250
-
(2013)
PLoS One
, vol.8
, pp. e75250
-
-
Jung, C.H.1
Lee, M.J.2
Hwang, J.Y.3
-
22
-
-
80052964907
-
Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008
-
Lee B-K, Kim Y, Kim Y-I. Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008. Metabolism 2011;60:1416-1424
-
(2011)
Metabolism
, vol.60
, pp. 1416-1424
-
-
Lee, B.-K.1
Kim, Y.2
Kim, Y.-I.3
-
23
-
-
33845334221
-
Fer-ritin and transferrin are both predictive of the onset of hyperglycemia in men and women over 3 years: The data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study
-
Fumeron F, Péan F, Driss F, et al.; Insulin Resistance Syndrome (DESIR) Study Group. Fer-ritin and transferrin are both predictive of the onset of hyperglycemia in men and women over 3 years: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study. Diabetes Care 2006;29:2090-2094
-
(2006)
Diabetes Care
, vol.29
, pp. 2090-2094
-
-
Fumeron, F.1
Péan, F.2
Driss, F.3
-
24
-
-
0036842476
-
Is an elevated serum transferrin saturation associated with the development of diabetes?
-
Mainous AG 3rd, King DE, Pearson WS, Garr DR. Is an elevated serum transferrin saturation associated with the development of diabetes? J Fam Pract 2002;51:933-936
-
(2002)
J Fam Pract
, vol.51
, pp. 933-936
-
-
Mainous, A.G.1
De, K.2
Pearson, W.S.3
Garr, D.R.4
-
25
-
-
84859002938
-
Elevated transferrin saturation and risk of diabetes: Three population-based studies
-
Ellervik C, Mandrup-Poulsen T, Andersen HU, et al. Elevated transferrin saturation and risk of diabetes: three population-based studies. Diabetes Care 2011;34:2256-2258
-
(2011)
Diabetes Care
, vol.34
, pp. 2256-2258
-
-
Ellervik, C.1
Mandrup-Poulsen, T.2
Andersen, H.U.3
-
26
-
-
84887627392
-
High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. Adults
-
Cheung CL, Cheung TT, Lam KS, Cheung BM. High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults. Clin Nutr 2013;32:1055-1060
-
(2013)
Clin Nutr
, vol.32
, pp. 1055-1060
-
-
Cheung, C.L.1
Cheung, T.T.2
Lam, K.S.3
Cheung, B.M.4
-
27
-
-
84928075999
-
Low transferrin saturation is associated with impaired fasting glucose and insulin resistance in the South Korean adults: The 2010 Korean National Health and Nutrition Examination Survey
-
Park RJ, Moon JD. Low transferrin saturation is associated with impaired fasting glucose and insulin resistance in the South Korean adults: the 2010 Korean National Health and Nutrition Examination Survey. Diabet Med 2015;32:673-678
-
(2015)
Diabet Med
, vol.32
, pp. 673-678
-
-
Park, R.J.1
Moon, J.D.2
-
28
-
-
84946061344
-
Bio-markers of iron metabolism are independently associated with impaired glucose metabolism and type 2 diabetes: The KORA F4 study
-
Huth C, Beuerle S, Zierer A, et al. Bio-markers of iron metabolism are independently associated with impaired glucose metabolism and type 2 diabetes: the KORA F4 study. Eur J Endocrinol 2015;173:643-653
-
(2015)
Eur J Endocrinol
, vol.173
, pp. 643-653
-
-
Huth, C.1
Beuerle, S.2
Zierer, A.3
-
29
-
-
84861330629
-
Diagnostic value of transferrin
-
Szöke D, Panteghini M. Diagnostic value of transferrin. Clin Chim Acta2012;413:1184-1189
-
(2012)
Clin Chim Acta
, vol.413
, pp. 1184-1189
-
-
Szöke, D.1
Panteghini, M.2
-
30
-
-
33746383083
-
Common presence of non-transferrin-bound iron among patients with type 2 diabetes
-
Lee D-HD-H, LiuDY, Jacobs DR Jr, et al. Common presence of non-transferrin-bound iron among patients with type 2 diabetes. Diabetes Care 2006;29:1090-1095
-
(2006)
Diabetes Care
, vol.29
, pp. 1090-1095
-
-
Lee, D.-H.D.-H.1
Liu, D.Y.2
Jacobs, D.R.3
-
31
-
-
0031028026
-
A new syndrome of liver iron overload with normal transferrin saturation
-
Moirand R, Mortaji AM, Loréal O, Paillard F, Brissot P, Deugnier Y. A new syndrome of liver iron overload with normal transferrin saturation. Lancet 1997;349:95-97
-
(1997)
Lancet
, vol.349
, pp. 95-97
-
-
Moirand, R.1
Mortaji, A.M.2
Loréal, O.3
Paillard, F.4
Brissot, P.5
Deugnier, Y.6
-
32
-
-
0032692722
-
Insulin resistance-associated hepatic iron overload
-
Mendler MH, Turlin B, Moirand R, et al. Insulin resistance-associated hepatic iron overload. Gastroenterology 1999;117:1155-1163
-
(1999)
Gastroenterology
, vol.117
, pp. 1155-1163
-
-
Mendler, M.H.1
Turlin, B.2
Moirand, R.3
-
33
-
-
0034767941
-
Histologic features of the liver in insulin resistance-associated iron overload. A study of 139 patients
-
Turlin B, Mendler MH, Moirand R, Guyader D, Guillygomarc'h A, Deugnier Y. Histologic features of the liver in insulin resistance-associated iron overload. A study of 139 patients. Am J Clin Pathol 2001;116:263-270
-
(2001)
Am J Clin Pathol
, vol.116
, pp. 263-270
-
-
Turlin, B.1
Mendler, M.H.2
Moirand, R.3
Guyader, D.4
Guillygomarc'H, A.5
Deugnier, Y.6
-
35
-
-
34147175589
-
Elevated serum ferritin levels predict new-onset type 2 diabetes: Results from the EPIC-Norfolk prospective study
-
Forouhi NG, Harding AH, Allison M, et al. Elevated serum ferritin levels predict new-onset type 2 diabetes: results from the EPIC-Norfolk prospective study. Diabetologia 2007;50:949-956
-
(2007)
Diabetologia
, vol.50
, pp. 949-956
-
-
Forouhi, N.G.1
Harding, A.H.2
Allison, M.3
-
36
-
-
84867167258
-
Adi-pocyte iron regulates adiponectin and insulin sensitivity
-
Gabrielsen JS, Gao Y, Simcox JA, et al. Adi-pocyte iron regulates adiponectin and insulin sensitivity. J Clin Invest 2012;122:3529-3540
-
(2012)
J Clin Invest
, vol.122
, pp. 3529-3540
-
-
Gabrielsen, J.S.1
Gao, Y.2
Simcox, J.A.3
-
37
-
-
84939875296
-
Iron metabolism is prospectively associated with insulin resistance and glucose intolerance over a 7-year follow-up period: The CODAM study
-
Wlazlo N, van Greevenbroek MM, Ferreira I, et al. Iron metabolism is prospectively associated with insulin resistance and glucose intolerance over a 7-year follow-up period: the CODAM study. Acta Diabetol 2015;52:337-348
-
(2015)
Acta Diabetol
, vol.52
, pp. 337-348
-
-
Wlazlo, N.1
Van Greevenbroek, M.M.2
Ferreira, I.3
-
38
-
-
0028815235
-
Insulin and counterregulatory hormones influence acute-phase protein production in human hepatocytes
-
O'Riordain MG, Ross JA, Fearon KC, et al. Insulin and counterregulatory hormones influence acute-phase protein production in human hepatocytes. Am J Physiol 1995;269:E323-E330
-
(1995)
Am J Physiol
, vol.269
, pp. E323-E330
-
-
O'Riordain, M.G.1
Ross, J.A.2
Fearon, K.C.3
-
39
-
-
0023227367
-
Insulin elicits a redistribution of transferrin receptors in 3T3-L1 adipocytes through an increase in the rate constant for receptor externalization
-
Tanner LI, Lienhard GE. Insulin elicits a redistribution of transferrin receptors in 3T3-L1 adipocytes through an increase in the rate constant for receptor externalization. J Biol Chem 1987;262:8975-8980
-
(1987)
J Biol Chem
, vol.262
, pp. 8975-8980
-
-
Tanner, L.I.1
Lienhard, G.E.2
-
40
-
-
0031897386
-
Insulin antagonism: A novel role for human serum transferrin
-
Vargas L, Kawada ME, Bazaes S, et al. Insulin antagonism: a novel role for human serum transferrin. Horm Metab Res 1998;30:113-117.
-
(1998)
Horm Metab Res
, vol.30
, pp. 113
-
-
Vargas, L.1
Kawada, M.E.2
Bazaes, S.3
-
41
-
-
4644337374
-
Elevations in markers of liver injury and risk of type 2 diabetes: The insulin resistance atherosclerosis study
-
Hanley AJ, Williams K, Festa A, et al.; Insulin Resistance Atherosclerosis Study. Elevations in markers of liver injury and risk of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes 2004;53:2623-2632
-
(2004)
Diabetes
, vol.53
, pp. 2623-2632
-
-
Hanley, A.J.1
Williams, K.2
Festa, A.3
-
42
-
-
79960202841
-
Type 2 diabetes across generations: From pathophysiology to prevention and management
-
Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet 2011; 378:169-181
-
(2011)
Lancet
, vol.378
, pp. 169-181
-
-
Nolan, C.J.1
Damm, P.2
Prentki, M.3
-
43
-
-
84879931036
-
HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level ,1000 mg/L
-
Adams PC, McLaren CE, Speechley M, McLaren GD, Barton JC, Eckfeldt JH. HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level ,1000 mg/L. Can J Gastroenterol 2013;27:390-392
-
(2013)
Can J Gastroenterol
, vol.27
, pp. 390-392
-
-
Adams, P.C.1
McLaren, C.E.2
Speechley, M.3
McLaren, G.D.4
Barton, J.C.5
Eckfeldt, J.H.6
-
44
-
-
20244372858
-
Hemochromatosis and iron-overload screening in a racially diverse population
-
Adams PC, Reboussin DM, Barton JC, et al.; Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators. Hemochromatosis and iron-overload screening in a racially diverse population. N Engl J Med 2005; 352:1769-1778
-
(2005)
N Engl J Med
, vol.352
, pp. 1769-1778
-
-
Adams, P.C.1
Reboussin, D.M.2
Barton, J.C.3
-
45
-
-
38349079861
-
Iron-overload-related disease in HFE hereditary hemochromatosis
-
Allen KJ, Gurrin LC, Constantine CC, et al. Iron-overload-related disease in HFE hereditary hemochromatosis. N Engl J Med 2008;358:221-230
-
(2008)
N Engl J Med
, vol.358
, pp. 221-230
-
-
Allen, K.J.1
Gurrin, L.C.2
Constantine, C.C.3
-
46
-
-
0037132786
-
Penetrance of 845G-. A (C282Y) HFE hereditary haemochromatosis mutation in the USA
-
Beutler E, Felitti VJ, Koziol JA, Ho NJ, Gelbart T. Penetrance of 845G-. A (C282Y) HFE hereditary haemochromatosis mutation in the USA. Lancet 2002;359:211-218
-
(2002)
Lancet
, vol.359
, pp. 211-218
-
-
Beutler, E.1
Felitti, V.J.2
Koziol, J.A.3
Ho, N.J.4
Gelbart, T.5
-
47
-
-
84871680844
-
Hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: A meta-analysis
-
RongY, BaoW, RongS, et al. Hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: a meta-analysis. Am J Epidemiol 2012;176:461-472
-
(2012)
Am J Epidemiol
, vol.176
, pp. 461-472
-
-
Baow Rongs, R.1
-
48
-
-
84873654177
-
Hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: A metaanalysis
-
Zhang D, Jiang X, Wu Y, Jiang W, Pang Z. Re: "hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: a metaanalysis". Am J Epidemiol 2013;177:372-373
-
(2013)
Am J Epidemiol
, vol.177
, pp. 372-373
-
-
Zhang, D.1
Jiang, X.2
Wu, Y.3
Jiang, W.4
Re, P.Z.5
-
49
-
-
38349079859
-
Clinical penetrance of hereditary hemochromatosis
-
Bacon BR, Britton RS. Clinical penetrance of hereditary hemochromatosis. N Engl J Med 2008;358:291-292
-
(2008)
N Engl J Med
, vol.358
, pp. 291-292
-
-
Bacon, B.R.1
Britton, R.S.2
|