Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells

Free Radical Biology and Medicine

Volumn 53, Issue 7, 2012, Pages 1489-1499

  Boudreau, Howard E ^a   Casterline, Benjamin W ^a   Rada, Balazs ^a   Korzeniowska, Agnieszka ^a   Leto, Thomas L ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Cell migration; Epithelial to mesenchymal transition (EMT); NADPH oxidase 4 (Nox4); TGF beta signaling

Indexed keywords

FIBRONECTIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SHORT HAIRPIN RNA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

ARTICLE; BREAST EPITHELIUM; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE SILENCING; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; WOUND HEALING;

CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FIBRONECTINS; GENE EXPRESSION REGULATION; HUMANS; ISOQUINOLINES; MAMMARY GLANDS, HUMAN; NADPH OXIDASE; PYRIDINES; PYRROLES; REACTIVE OXYGEN SPECIES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84866390484     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.06.016     Document Type: Article

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