Intra-nasal dopamine alleviates cognitive deficits in tgDISC1 rats which overexpress the human DISC1 gene

Neurobiology of Learning and Memory

Volumn 146, Issue , 2017, Pages 12-20

  Wang, An Li ^a   Fazari, Benedetta ^a   Chao, Owen Y ^a,b   Nikolaus, Susanne ^c   Trossbach, Svenja V ^d   Korth, Carsten ^d   Sialana, Fernando J ^e   Lubec, Gert ^e   Huston, Joseph P ^a   Mattern, Claudia ^f,g   de Souza Silva, Maria Angelica ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^d Department of Orthopedic Surgery   (Germany)

^e UNIVERSITY OF VIENNA   (Austria)

^f M et P Pharma AG   (Switzerland)

^g NOVA SOUTHEASTERN UNIVERSITY   (United States)

Author keywords

Animal model; Attention; DISC1; Intranasal dopamine; Memory; Novel object exploration

Indexed keywords

ACETYLCHOLINE; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; DOPAMINE; NORADRENALIN; SEROTONIN; DISC1 PROTEIN, HUMAN; NERVE PROTEIN;

AMYGDALA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENTION; BRAIN LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; DISC1 GENE; GENE OVEREXPRESSION; HIPPOCAMPUS; LONG TERM MEMORY; MALE; MEMORY DISORDER; NEOSTRIATUM; NONHUMAN; NUCLEUS ACCUMBENS; RAT; SHORT TERM MEMORY; TRANSGENIC RAT; ANIMAL; ANIMAL BEHAVIOR; DEFICIENCY; DISEASE MODEL; DRUG EFFECT; GENETICS; INTRANASAL DRUG ADMINISTRATION; METABOLISM; SPRAGUE DAWLEY RAT;

ADMINISTRATION, INTRANASAL; ANIMALS; ATTENTION; BEHAVIOR, ANIMAL; COGNITIVE DYSFUNCTION; DISEASE MODELS, ANIMAL; DOPAMINE; MALE; MEMORY, LONG-TERM; MEMORY, SHORT-TERM; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC;

EID: 85032705500     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2017.10.015     Document Type: Article

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