-
2
-
-
0000378637
-
On the antibacterial action of cultures of a Penicillium, with special reference to their use in the isolation of B. Influenza
-
Fleming, A. On the antibacterial action of cultures of a Penicillium, with special reference to their use in the isolation of B. influenzae. Br. J. Exp. Pathol. 1929, 10, 226-236.
-
(1929)
Br. J. Exp. Pathol.
, vol.10
, pp. 226-236
-
-
Fleming, A.1
-
3
-
-
84955461306
-
Antibacterial drug discovery in the resistance era
-
Brown, E. D.; Wright, G. D. Antibacterial drug discovery in the resistance era. Nature 2016, 529, 336-343.
-
(2016)
Nature
, vol.529
, pp. 336-343
-
-
Brown, E.D.1
Wright, G.D.2
-
4
-
-
84923611351
-
Molecular mechanisms of antibiotic resistance
-
Blair, J. M.; Webber, M. A.; Baylay, A. J.; Ogbolu, D. O.; Piddock, L. J. Molecular mechanisms of antibiotic resistance. Nat. Rev. Microbiol. 2015, 13, 42-51.
-
(2015)
Nat. Rev. Microbiol.
, vol.13
, pp. 42-51
-
-
Blair, J.M.1
Webber, M.A.2
Baylay, A.J.3
Ogbolu, D.O.4
Piddock, L.J.5
-
5
-
-
42549171131
-
Federal funding for the study of antimicrobial resistance in nosocomial pathogens: No ESKAPE
-
Rice, L. B. Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE. J. Infect. Dis. 2008, 197, 1079-1081.
-
(2008)
J. Infect. Dis.
, vol.197
, pp. 1079-1081
-
-
Rice, L.B.1
-
6
-
-
85019106609
-
Origins of combination therapy for tuberculosis: Lessons for future antimicrobial development and application
-
Kerantzas, C. A.; Jacobs, W. R., Jr. Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application. mBio 2017, 8, No. e01586.
-
(2017)
MBio
, vol.8
, pp. e01586
-
-
Kerantzas, C.A.1
Jacobs, W.R.2
-
7
-
-
84892698163
-
Molecular biology of drug resistance in Mycobacterium tuberculosis
-
Smith, T.; Wolff, K. A.; Nguyen, L. Molecular biology of drug resistance in Mycobacterium tuberculosis. Curr. Top. Microbiol. Immunol. 2013, 374, 53-80.
-
(2013)
Curr. Top. Microbiol. Immunol.
, vol.374
, pp. 53-80
-
-
Smith, T.1
Wolff, K.A.2
Nguyen, L.3
-
8
-
-
0034038098
-
A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus
-
Katayama, Y.; Ito, T.; Hiramatsu, K. A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. Antimicrob. Agents Chemother. 2000, 44, 1549-1555.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 1549-1555
-
-
Katayama, Y.1
Ito, T.2
Hiramatsu, K.3
-
9
-
-
20344367084
-
A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA
-
Hegde, S. S.; Vetting, M. W.; Roderick, S. L.; Mitchenall, L. A.; Maxwell, A.; Takiff, H. E.; Blanchard, J. S. A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA. Science 2005, 308, 1480-1483.
-
(2005)
Science
, vol.308
, pp. 1480-1483
-
-
Hegde, S.S.1
Vetting, M.W.2
Roderick, S.L.3
Mitchenall, L.A.4
Maxwell, A.5
Takiff, H.E.6
Blanchard, J.S.7
-
10
-
-
84855286330
-
The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance
-
Burian, J.; Ramon-Garcia, S.; Sweet, G.; Gomez-Velasco, A.; Av- Gay, Y.; Thompson, C. J. The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance. J. Biol. Chem. 2012, 287, 299-310.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 299-310
-
-
Burian, J.1
Ramon-Garcia, S.2
Sweet, G.3
Gomez-Velasco, A.4
Av-Gay, Y.5
Thompson, C.J.6
-
11
-
-
84879072389
-
Microbial persistence and the road to drug resistance
-
Cohen, N. R.; Lobritz, M. A.; Collins, J. J. Microbial persistence and the road to drug resistance. Cell Host Microbe 2013, 13, 632-642.
-
(2013)
Cell Host Microbe
, vol.13
, pp. 632-642
-
-
Cohen, N.R.1
Lobritz, M.A.2
Collins, J.J.3
-
12
-
-
85006247350
-
Mechanisms of bacterial persistence during stress and antibiotic exposure
-
No. aaf4268
-
Harms, A.; Maisonneuve, E.; Gerdes, K. Mechanisms of bacterial persistence during stress and antibiotic exposure. Science 2016, 354, No. aaf4268.
-
(2016)
Science
, pp. 354
-
-
Harms, A.1
Maisonneuve, E.2
Gerdes, K.3
-
13
-
-
81555212273
-
Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria
-
Nguyen, D.; Joshi-Datar, A.; Lepine, F.; Bauerle, E.; Olakanmi, O.; Beer, K.; McKay, G.; Siehnel, R.; Schafhauser, J.; Wang, Y.; Britigan, B. E.; Singh, P. K. Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria. Science 2011, 334, 982-986.
-
(2011)
Science
, vol.334
, pp. 982-986
-
-
Nguyen, D.1
Joshi-Datar, A.2
Lepine, F.3
Bauerle, E.4
Olakanmi, O.5
Beer, K.6
McKay, G.7
Siehnel, R.8
Schafhauser, J.9
Wang, Y.10
Britigan, B.E.11
Singh, P.K.12
-
14
-
-
84883342218
-
(p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity
-
Maisonneuve, E.; Castro-Camargo, M.; Gerdes, K. (p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity. Cell 2013, 154, 1140-1150.
-
(2013)
Cell
, vol.154
, pp. 1140-1150
-
-
Maisonneuve, E.1
Castro-Camargo, M.2
Gerdes, K.3
-
15
-
-
84878204775
-
Metabolic control of persister formation in Escherichia coli
-
Amato, S. M.; Orman, M. A.; Brynildsen, M. P. Metabolic control of persister formation in Escherichia coli. Mol. Cell 2013, 50, 475-487.
-
(2013)
Mol. Cell
, vol.50
, pp. 475-487
-
-
Amato, S.M.1
Orman, M.A.2
Brynildsen, M.P.3
-
16
-
-
0033591467
-
Bacterial biofilms: A common cause of persistent infections
-
Costerton, J. W.; Stewart, P. S.; Greenberg, E. P. Bacterial biofilms: a common cause of persistent infections. Science 1999, 284, 1318-1322.
-
(1999)
Science
, vol.284
, pp. 1318-1322
-
-
Costerton, J.W.1
Stewart, P.S.2
Greenberg, E.P.3
-
17
-
-
84890131771
-
Essential roles for Mycobacterium tuberculosis Rel beyond the production of (p)ppGpp
-
Weiss, L. A.; Stallings, C. L. Essential roles for Mycobacterium tuberculosis Rel beyond the production of (p)ppGpp. J. Bacteriol. 2013, 195, 5629-5638.
-
(2013)
J. Bacteriol.
, vol.195
, pp. 5629-5638
-
-
Weiss, L.A.1
Stallings, C.L.2
-
18
-
-
84928435794
-
Recent functional insights into the role of (p)ppGpp in bacterial physiology
-
Hauryliuk, V.; Atkinson, G. C.; Murakami, K. S.; Tenson, T.; Gerdes, K. Recent functional insights into the role of (p)ppGpp in bacterial physiology. Nat. Rev. Microbiol. 2015, 13, 298-309.
-
(2015)
Nat. Rev. Microbiol.
, vol.13
, pp. 298-309
-
-
Hauryliuk, V.1
Atkinson, G.C.2
Murakami, K.S.3
Tenson, T.4
Gerdes, K.5
-
19
-
-
84866903496
-
Relacin a novel antibacterial agent targeting the Stringent Response
-
No. e1002925
-
Wexselblatt, E.; Oppenheimer-Shaanan, Y.; Kaspy, I.; London, N.; Schueler-Furman, O.; Yavin, E.; Glaser, G.; Katzhendler, J.; Ben- Yehuda, S. Relacin, a novel antibacterial agent targeting the Stringent Response. PLoS Pathog. 2012, 8, No. e1002925.
-
(2012)
PLoS Pathog.
, vol.8
-
-
Wexselblatt, E.1
Oppenheimer-Shaanan, Y.2
Kaspy, I.3
London, N.4
Schueler-Furman, O.5
Yavin, E.6
Glaser, G.7
Katzhendler, J.8
Ben-Yehuda, S.9
-
20
-
-
84886738771
-
Design synthesis and structure-activity relationship of novel Relacin analogs as inhibitors of Rel proteins
-
Wexselblatt, E.; Kaspy, I.; Glaser, G.; Katzhendler, J.; Yavin, E. Design, synthesis and structure-activity relationship of novel Relacin analogs as inhibitors of Rel proteins. Eur. J. Med. Chem. 2013, 70, 497-504.
-
(2013)
Eur. J. Med. Chem.
, vol.70
, pp. 497-504
-
-
Wexselblatt, E.1
Kaspy, I.2
Glaser, G.3
Katzhendler, J.4
Yavin, E.5
-
21
-
-
85019705733
-
Synthetic (p)ppGpp Analogue Is an Inhibitor of Stringent Response in Mycobacteria
-
No. e00443
-
Syal, K.; Flentie, K.; Bhardwaj, N.; Maiti, K.; Jayaraman, N.; Stallings, C. L.; Chatterji, D. Synthetic (p)ppGpp Analogue Is an Inhibitor of Stringent Response in Mycobacteria. Antimicrob. Agents Chemother. 2017, 61, No. e00443.
-
(2017)
Antimicrob. Agents Chemother.
, vol.61
-
-
Syal, K.1
Flentie, K.2
Bhardwaj, N.3
Maiti, K.4
Jayaraman, N.5
Stallings, C.L.6
Chatterji, D.7
-
22
-
-
84878682986
-
Mycobacterium tuberculosis is extraordinarily sensitive to killing by a Vitamin C-induced Fenton reaction
-
Vilchèze, C.; Hartman, T.; Weinrick, B.; Jacobs, W. R., Jr. Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction. Nat. Commun. 2013, 4, No. 1881.
-
(2013)
Nat. Commun.
, vol.4
, Issue.1881
-
-
Vilchèze, C.1
Hartman, T.2
Weinrick, B.3
Jacobs, W.R.4
-
23
-
-
85014350645
-
Vitamin C targets (p)ppGpp synthesis leading to stalling of long-term survival and biofilm formation in Mycobacterium smegmatis
-
No. fnw282
-
Syal, K.; Bhardwaj, N.; Chatterji, D. Vitamin C targets (p)ppGpp synthesis leading to stalling of long-term survival and biofilm formation in Mycobacterium smegmatis. FEMS Microbiol. Lett. 2017, 364, No. fnw282.
-
(2017)
FEMS Microbiol. Lett.
, vol.364
-
-
Syal, K.1
Bhardwaj, N.2
Chatterji, D.3
-
24
-
-
84940416485
-
From (p)ppgpp to (pp)pgpp: Characterization of regulatory effects of pgpp synthesized by the small alarmone synthetase of enterococcus faecalis
-
Gaca, A. O.; Kudrin, P.; Colomer-Winter, C.; Beljantseva, J.; Liu, K.; Anderson, B.; Wang, J. D.; Rejman, D.; Potrykus, K.; Cashel, M.; Hauryliuk, V.; Lemos, J. A. From (p)ppGpp to (pp)pGpp: Characterization of Regulatory Effects of pGpp Synthesized by the Small Alarmone Synthetase of Enterococcus faecalis. J. Bacteriol. 2015, 197, 2908-2919.
-
(2015)
J. Bacteriol.
, vol.197
, pp. 2908-2919
-
-
Gaca, A.O.1
Kudrin, P.2
Colomer-Winter, C.3
Beljantseva, J.4
Liu, K.5
Anderson, B.6
Wang, J.D.7
Rejman, D.8
Potrykus, K.9
Cashel, M.10
Hauryliuk, V.11
Lemos, J.A.12
-
25
-
-
85016959996
-
Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA
-
Beljantseva, J.; Kudrin, P.; Andresen, L.; Shingler, V.; Atkinson, G. C.; Tenson, T.; Hauryliuk, V. Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA. Proc. Natl. Acad. Sci. U.S.A. 2017, 114, 3726-3731.
-
(2017)
Proc. Natl. Acad. Sci. U.S.A.
, vol.114
, pp. 3726-3731
-
-
Beljantseva, J.1
Kudrin, P.2
Andresen, L.3
Shingler, V.4
Atkinson, G.C.5
Tenson, T.6
Hauryliuk, V.7
-
26
-
-
84953923744
-
Bacterial signal transduction by cyclic Di-GMP and other nucleotide second messengers
-
Hengge, R.; Grundling, A.; Jenal, U.; Ryan, R.; Yildiz, F. Bacterial Signal Transduction by Cyclic Di-GMP and Other Nucleotide Second Messengers. J. Bacteriol. 2016, 198, 15-26.
-
(2016)
J. Bacteriol.
, vol.198
, pp. 15-26
-
-
Hengge, R.1
Grundling, A.2
Jenal, U.3
Ryan, R.4
Yildiz, F.5
-
27
-
-
0033758602
-
Biofilm formation as microbial development
-
O'Toole, G.; Kaplan, H. B.; Kolter, R. Biofilm formation as microbial development. Annu. Rev. Microbiol. 2000, 54, 49-79.
-
(2000)
Annu. Rev. Microbiol.
, vol.54
, pp. 49-79
-
-
O'Toole, G.1
Kaplan, H.B.2
Kolter, R.3
-
28
-
-
84974574369
-
Antibiofilm peptides: Potential as broad-spectrum agents
-
Pletzer, D.; Hancock, R. E. Antibiofilm Peptides: Potential as Broad-Spectrum Agents. J. Bacteriol. 2016, 198, 2572-2578.
-
(2016)
J. Bacteriol.
, vol.198
, pp. 2572-2578
-
-
Pletzer, D.1
Hancock, R.E.2
-
29
-
-
51949104801
-
Human host defense peptide LL-37 prevents bacterial biofilm formation
-
Overhage, J.; Campisano, A.; Bains, M.; Torfs, E. C.; Rehm, B. H.; Hancock, R. E. Human host defense peptide LL-37 prevents bacterial biofilm formation. Infect. Immun. 2008, 76, 4176-4782.
-
(2008)
Infect. Immun.
, vol.76
, pp. 4176-4782
-
-
Overhage, J.1
Campisano, A.2
Bains, M.3
Torfs, E.C.4
Rehm, B.H.5
Hancock, R.E.6
-
30
-
-
84942991136
-
High throughput screening methods for assessing antibiofilm and immunomodulatory activities of synthetic peptides
-
Haney, E. F.; Mansour, S. C.; Hilchie, A. L.; de la Fuente-Nunez, C.; Hancock, R. E. High throughput screening methods for assessing antibiofilm and immunomodulatory activities of synthetic peptides. Peptides 2015, 71, 276-285.
-
(2015)
Peptides
, vol.71
, pp. 276-285
-
-
Haney, E.F.1
Mansour, S.C.2
Hilchie, A.L.3
De La Fuente-Nunez, C.4
Hancock, R.E.5
-
31
-
-
84923122512
-
D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections
-
de la Fuente-Núñez, C.; Reffuveille, F.; Mansour, S. C.; Reckseidler-Zenteno, S. L.; Hernandez, D.; Brackman, G.; Coenye, T.; Hancock, R. E. D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections. Chem. Biol. 2015, 22, 196-205.
-
(2015)
Chem. Biol.
, vol.22
, pp. 196-205
-
-
De La Fuente-Núñez, C.1
Reffuveille, F.2
Mansour, S.C.3
Reckseidler-Zenteno, S.L.4
Hernandez, D.5
Brackman, G.6
Coenye, T.7
Hancock, R.E.8
-
32
-
-
84994526175
-
Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp
-
No. 36549
-
Andresen, L.; Tenson, T.; Hauryliuk, V. Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp. Sci. Rep. 2016, 6, No. 36549.
-
(2016)
Sci. Rep.
, pp. 6
-
-
Andresen, L.1
Tenson, T.2
Hauryliuk, V.3
-
33
-
-
85027999471
-
Lactoferricin Peptides Increase Macrophages' Capacity to Kill Mycobacterium avium
-
No. e00301
-
Silva, T.; Moreira, A. C.; Nazmi, K.; Moniz, T.; Vale, N.; Rangel, M.; Gomes, P.; Bolscher, J. G. M.; Rodrigues, P. N.; Bastos, M.; Gomes, M. S. Lactoferricin Peptides Increase Macrophages' Capacity To Kill Mycobacterium avium. mSphere 2017, 2, No. e00301.
-
(2017)
MSphere
, vol.2
-
-
Silva, T.1
Moreira, A.C.2
Nazmi, K.3
Moniz, T.4
Vale, N.5
Rangel, M.6
Gomes, P.7
Bolscher, J.G.M.8
Rodrigues, P.N.9
Bastos, M.10
Gomes, M.S.11
-
34
-
-
84872543206
-
A decade of riboswitches
-
Serganov, A.; Nudler, E. A decade of riboswitches. Cell 2013, 152, 17-24.
-
(2013)
Cell
, vol.152
, pp. 17-24
-
-
Serganov, A.1
Nudler, E.2
-
35
-
-
85011936077
-
Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression
-
Lee, E. R.; Blount, K. F.; Breaker, R. R. Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression. RNA Biol. 2009, 6, 187-194.
-
(2009)
RNA Biol.
, vol.6
, pp. 187-194
-
-
Lee, E.R.1
Blount, K.F.2
Breaker, R.R.3
-
36
-
-
84945577962
-
Selective small-molecule inhibition of an RNA structural element
-
Howe, J. A.; Wang, H.; Fischmann, T. O.; Balibar, C. J.; Xiao, L.; Galgoci, A. M.; Malinverni, J. C.; Mayhood, T.; Villafania, A.; Nahvi, A.; Murgolo, N.; Barbieri, C. M.; Mann, P. A.; Carr, D.; Xia, E.; Zuck, P.; Riley, D.; Painter, R. E.; Walker, S. S.; Sherborne, B.; de Jesus, R.; Pan, W.; Plotkin, M. A.; Wu, J.; Rindgen, D.; Cummings, J.; Garlisi, C. G.; Zhang, R.; Sheth, P. R.; Gill, C. J.; Tang, H.; Roemer, T. Selective small-molecule inhibition of an RNA structural element. Nature 2015, 526, 672-677.
-
(2015)
Nature
, vol.526
, pp. 672-677
-
-
Howe, J.A.1
Wang, H.2
Fischmann, T.O.3
Balibar, C.J.4
Xiao, L.5
Galgoci, A.M.6
Malinverni, J.C.7
Mayhood, T.8
Villafania, A.9
Nahvi, A.10
Murgolo, N.11
Barbieri, C.M.12
Mann, P.A.13
Carr, D.14
Xia, E.15
Zuck, P.16
Riley, D.17
Painter, R.E.18
Walker, S.S.19
Sherborne, B.20
De Jesus, R.21
Pan, W.22
Plotkin, M.A.23
Wu, J.24
Rindgen, D.25
Cummings, J.26
Garlisi, C.G.27
Zhang, R.28
Sheth, P.R.29
Gill, C.J.30
Tang, H.31
Roemer, T.32
more..
-
37
-
-
85009517257
-
Non-coding RNAs as antibiotic targets
-
Colameco, S.; Elliot, M. A. Non-coding RNAs as antibiotic targets. Biochem. Pharmacol. 2017, 133, 29-42.
-
(2017)
Biochem. Pharmacol.
, vol.133
, pp. 29-42
-
-
Colameco, S.1
Elliot, M.A.2
-
38
-
-
84922444526
-
Regulatory small RNAs from the 3′ regions of bacterial mRNAs
-
Miyakoshi, M.; Chao, Y.; Vogel, J. Regulatory small RNAs from the 3′ regions of bacterial mRNAs. Curr. Opin. Microbiol. 2015, 24, 132-139.
-
(2015)
Curr. Opin. Microbiol.
, vol.24
, pp. 132-139
-
-
Miyakoshi, M.1
Chao, Y.2
Vogel, J.3
-
39
-
-
84906061867
-
Involvement of Enterococcus faecalis small RNAs in stress response and virulence
-
Michaux, C.; Hartke, A.; Martini, C.; Reiss, S.; Albrecht, D.; Budin-Verneuil, A.; Sanguinetti, M.; Engelmann, S.; Hain, T.; Verneuil, N.; Giard, J. C. Involvement of Enterococcus faecalis small RNAs in stress response and virulence. Infect. Immun. 2014, 82, 3599-3611.
-
(2014)
Infect. Immun.
, vol.82
, pp. 3599-3611
-
-
Michaux, C.1
Hartke, A.2
Martini, C.3
Reiss, S.4
Albrecht, D.5
Budin-Verneuil, A.6
Sanguinetti, M.7
Engelmann, S.8
Hain, T.9
Verneuil, N.10
Giard, J.C.11
-
40
-
-
84906092799
-
Cellbased assay to identify inhibitors of the Hfq-sRNA regulatory pathway
-
El-Mowafi, S. A.; Alumasa, J. N.; Ades, S. E.; Keiler, K. C. Cellbased assay to identify inhibitors of the Hfq-sRNA regulatory pathway. Antimicrob. Agents Chemother. 2014, 58, 5500-5509.
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 5500-5509
-
-
El-Mowafi, S.A.1
Alumasa, J.N.2
Ades, S.E.3
Keiler, K.C.4
-
41
-
-
85019080696
-
Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery
-
No. e00272
-
Bald, D.; Villellas, C.; Lu, P.; Koul, A. Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery. mBio 2017, 8, No. e00272.
-
(2017)
MBio
, vol.8
-
-
Bald, D.1
Villellas, C.2
Lu, P.3
Koul, A.4
-
42
-
-
85018815386
-
Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis
-
Vilchèze, C.; Hartman, T.; Weinrick, B.; Jain, P.; Weisbrod, T. R.; Leung, L. W.; Freundlich, J. S.; Jacobs, W. R., Jr. Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2017, 114, 4495-4500.
-
(2017)
Proc. Natl. Acad. Sci. U.S.A.
, vol.114
, pp. 4495-4500
-
-
Vilchèze, C.1
Hartman, T.2
Weinrick, B.3
Jain, P.4
Weisbrod, T.R.5
Leung, L.W.6
Freundlich, J.S.7
Jacobs, W.R.8
-
43
-
-
85027521746
-
Targeting mycobacterium tuberculosis sensitivity to thiol stress at acidic ph kills the bacterium and potentiates antibiotics
-
993.e4
-
Coulson, G. B.; Johnson, B. K.; Zheng, H.; Colvin, C. J.; Fillinger, R. J.; Haiderer, E. R.; Hammer, N. D.; Abramovitch, R. B. Targeting Mycobacterium tuberculosis Sensitivity to Thiol Stress at Acidic pH Kills the Bacterium and Potentiates Antibiotics. Cell Chem. Biol. 2017, 24, No. 993.e4.
-
(2017)
Cell Chem. Biol.
, vol.24
-
-
Coulson, G.B.1
Johnson, B.K.2
Zheng, H.3
Colvin, C.J.4
Fillinger, R.J.5
Haiderer, E.R.6
Hammer, N.D.7
Abramovitch, R.B.8
-
44
-
-
85027831330
-
A small-molecule allosteric inhibitor of mycobacterium tuberculosis tryptophan synthase
-
Wellington, S.; Nag, P. P.; Michalska, K.; Johnston, S. E.; Jedrzejczak, R. P.; Kaushik, V. K.; Clatworthy, A. E.; Siddiqi, N.; McCarren, P.; Bajrami, B.; Maltseva, N. I.; Combs, S.; Fisher, S. L.; Joachimiak, A.; Schreiber, S. L.; Hung, D. T. A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase. Nat. Chem. Biol. 2017, 13, 943-950.
-
(2017)
Nat. Chem. Biol.
, vol.13
, pp. 943-950
-
-
Wellington, S.1
Nag, P.P.2
Michalska, K.3
Johnston, S.E.4
Jedrzejczak, R.P.5
Kaushik, V.K.6
Clatworthy, A.E.7
Siddiqi, N.8
McCarren, P.9
Bajrami, B.10
Maltseva, N.I.11
Combs, S.12
Fisher, S.L.13
Joachimiak, A.14
Schreiber, S.L.15
Hung, D.T.16
-
45
-
-
85019581867
-
Predictive compound accumulation rules yield a broad-spectrum antibiotic
-
Richter, M. F.; Drown, B. S.; Riley, A. P.; Garcia, A.; Shirai, T.; Svec, R. L.; Hergenrother, P. J. Predictive compound accumulation rules yield a broad-spectrum antibiotic. Nature 2017, 545, 299-304.
-
(2017)
Nature
, vol.545
, pp. 299-304
-
-
Richter, M.F.1
Drown, B.S.2
Riley, A.P.3
Garcia, A.4
Shirai, T.5
Svec, R.L.6
Hergenrother, P.J.7
-
46
-
-
85015314938
-
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
-
Blondiaux, N.; Moune, M.; Desroses, M.; Frita, R.; Flipo, M.; Mathys, V.; Soetaert, K.; Kiass, M.; Delorme, V.; Djaout, K.; Trebosc, V.; Kemmer, C.; Wintjens, R.; Wohlkonig, A.; Antoine, R.; Huot, L.; Hot, D.; Coscolla, M.; Feldmann, J.; Gagneux, S.; Locht, C.; Brodin, P.; Gitzinger, M.; Deprez, B.; Willand, N.; Baulard, A. R. Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420. Science 2017, 355, 1206-1211.
-
(2017)
Science
, vol.355
, pp. 1206-1211
-
-
Blondiaux, N.1
Moune, M.2
Desroses, M.3
Frita, R.4
Flipo, M.5
Mathys, V.6
Soetaert, K.7
Kiass, M.8
Delorme, V.9
Djaout, K.10
Trebosc, V.11
Kemmer, C.12
Wintjens, R.13
Wohlkonig, A.14
Antoine, R.15
Huot, L.16
Hot, D.17
Coscolla, M.18
Feldmann, J.19
Gagneux, S.20
Locht, C.21
Brodin, P.22
Gitzinger, M.23
Deprez, B.24
Willand, N.25
Baulard, A.R.26
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