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Volumn 76, Issue 9, 2008, Pages 4176-4182

Human host defense peptide LL-37 prevents bacterial biofilm formation

Author keywords

[No Author keywords available]

Indexed keywords

BACTENECIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; POLYMYXIN B;

EID: 51949104801     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00318-08     Document Type: Article
Times cited : (561)

References (56)
  • 1
    • 0037721339 scopus 로고    scopus 로고
    • Lactoferrin and lactoferricin inhibit herpes simplex 1 and 2 infection and exhibit synergy when combined with acyclovir
    • Andersen, J. H., H. Jenssen, and T. J. Gutteberg. 2003. Lactoferrin and lactoferricin inhibit herpes simplex 1 and 2 infection and exhibit synergy when combined with acyclovir. Antiviral Res. 58:209-215.
    • (2003) Antiviral Res , vol.58 , pp. 209-215
    • Andersen, J.H.1    Jenssen, H.2    Gutteberg, T.J.3
  • 2
    • 0032482980 scopus 로고    scopus 로고
    • The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface
    • Bals, R., X. Wang, M. Zasloff, and J. M. Wilson. 1998. The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc. Natl. Acad. Sci. USA 95:9541-9546.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9541-9546
    • Bals, R.1    Wang, X.2    Zasloff, M.3    Wilson, J.M.4
  • 6
    • 0027428420 scopus 로고
    • Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis
    • Britigan, B. E., M. B. Hayek, B. N. Doebbeling, and R. B. Fick, Jr. 1993. Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis. Infect. Immun. 61:5049-5055.
    • (1993) Infect. Immun , vol.61 , pp. 5049-5055
    • Britigan, B.E.1    Hayek, M.B.2    Doebbeling, B.N.3    Fick Jr, R.B.4
  • 8
    • 30044452344 scopus 로고    scopus 로고
    • Cationic host defense (antimicrobial) peptides
    • Brown, K. L., and R. E. W. Hancock. 2006. Cationic host defense (antimicrobial) peptides. Curr. Opin. Immunol. 18:24-30.
    • (2006) Curr. Opin. Immunol , vol.18 , pp. 24-30
    • Brown, K.L.1    Hancock, R.E.W.2
  • 10
    • 0032908465 scopus 로고    scopus 로고
    • The Calgary biofilm device: New technology for rapid determination of antibiotic susceptibilities of bacterial biofilms
    • Ceri, H., M. E. Olsen, C. Stremick, R. R. Read, D. Morck, and A. Buret. 1999. The Calgary biofilm device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms. J. Clin. Microbiol. 37:1771-1776.
    • (1999) J. Clin. Microbiol , vol.37 , pp. 1771-1776
    • Ceri, H.1    Olsen, M.E.2    Stremick, C.3    Read, R.R.4    Morck, D.5    Buret, A.6
  • 11
    • 0033591467 scopus 로고    scopus 로고
    • Bacterial biofilms: A common cause of persistent infections
    • Costerton, J. W., P. S. Stewart, and E. P. Greenberg. 1999. Bacterial biofilms: a common cause of persistent infections. Science 284:1318-1322.
    • (1999) Science , vol.284 , pp. 1318-1322
    • Costerton, J.W.1    Stewart, P.S.2    Greenberg, E.P.3
  • 12
    • 0037129218 scopus 로고    scopus 로고
    • Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation
    • Drenkard, E., and F. M. Ausubel. 2002. Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation. Nature 416:740-743.
    • (2002) Nature , vol.416 , pp. 740-743
    • Drenkard, E.1    Ausubel, F.M.2
  • 13
  • 14
    • 0036228505 scopus 로고    scopus 로고
    • Biofilms: Survival mechanisms of clinically relevant microorganisms
    • Donlan, R. M., and J. W. Costerton. 2002. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 15:167-193.
    • (2002) Clin. Microbiol. Rev , vol.15 , pp. 167-193
    • Donlan, R.M.1    Costerton, J.W.2
  • 15
    • 1242297814 scopus 로고    scopus 로고
    • Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms
    • Friedman, L., and R. Kolter. 2004. Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms. Mol. Microbiol. 51:675-690.
    • (2004) Mol. Microbiol , vol.51 , pp. 675-690
    • Friedman, L.1    Kolter, R.2
  • 16
    • 0033826385 scopus 로고    scopus 로고
    • Antibiotic resistance in Pseudomonas aeruginosa: Mechanisms and impact on treatment
    • Hancock, R. E. W., and D. P. Speert. 2000. Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and impact on treatment. Drug 3:247-255.
    • (2000) Drug , vol.3 , pp. 247-255
    • Hancock, R.E.W.1    Speert, D.P.2
  • 17
    • 0036244378 scopus 로고    scopus 로고
    • Persistent and aggressive bacteria in the lungs of cystic fibrosis children
    • Hart, C. A., and C. Winstaney. 2002. Persistent and aggressive bacteria in the lungs of cystic fibrosis children. Br. Med. Bull. 61:81-96.
    • (2002) Br. Med. Bull , vol.61 , pp. 81-96
    • Hart, C.A.1    Winstaney, C.2
  • 18
    • 23444451770 scopus 로고    scopus 로고
    • High-throughput generation of small antibacterial peptides with improved activity
    • Hilpert, K., R. Volkmer-Engert, T. Walter, and R. E. Hancock. 2005. High-throughput generation of small antibacterial peptides with improved activity. Nat. Biotechnol. 23:1008-1012.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1008-1012
    • Hilpert, K.1    Volkmer-Engert, R.2    Walter, T.3    Hancock, R.E.4
  • 21
    • 0032696604 scopus 로고    scopus 로고
    • Pathogenicity of microbes associated with cystic fibrosis
    • Hutchison, M. L., and J. R. Govan. 1999. Pathogenicity of microbes associated with cystic fibrosis. Microbes Infect. 1:1005-1014.
    • (1999) Microbes Infect , vol.1 , pp. 1005-1014
    • Hutchison, M.L.1    Govan, J.R.2
  • 22
    • 34948847090 scopus 로고    scopus 로고
    • High-throughput screens for small-molecule inhibitors of Pseudomonas aeruginosa biofilm development
    • Junker, L. M., and J. Clardy. 2007. High-throughput screens for small-molecule inhibitors of Pseudomonas aeruginosa biofilm development. Antimicrob. Agents Chemother. 51:3582-3590.
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 3582-3590
    • Junker, L.M.1    Clardy, J.2
  • 23
    • 34147096980 scopus 로고    scopus 로고
    • The transition metal gallium disrupts Pseudomonas aeruginosa iron metabolism and has antimicrobial and antibiofilm activity
    • Kaneko, Y., M. Thoendel, O. Olakanmi, B. E. Britigan, and P. K. Singh. 2007. The transition metal gallium disrupts Pseudomonas aeruginosa iron metabolism and has antimicrobial and antibiofilm activity. J. Clin. Investig. 117:877-888.
    • (2007) J. Clin. Investig , vol.117 , pp. 877-888
    • Kaneko, Y.1    Thoendel, M.2    Olakanmi, O.3    Britigan, B.E.4    Singh, P.K.5
  • 24
    • 0033758742 scopus 로고    scopus 로고
    • Swarming of Pseudomonas aeruginosa is dependent on cell-to-cell signaling and requires flagella and pili
    • Köhler, T., L. K. Curty, F. Barja, C. van Delden, J. C. Pechere. 2000. Swarming of Pseudomonas aeruginosa is dependent on cell-to-cell signaling and requires flagella and pili. J. Bacteriol. 182:5990-5996.
    • (2000) J. Bacteriol , vol.182 , pp. 5990-5996
    • Köhler, T.1    Curty, L.K.2    Barja, F.3    van Delden, C.4    Pechere, J.C.5
  • 26
    • 0033759942 scopus 로고    scopus 로고
    • Role of Pseudomonas aeruginosa PhoP-PhoQ in resistance to antimicrobial cationic peptides and aminoglycosides
    • Macfarlane, E. L., A. Kwasnicka, and R. E. W. Hancock. 2000. Role of Pseudomonas aeruginosa PhoP-PhoQ in resistance to antimicrobial cationic peptides and aminoglycosides. Microbiology 146:2543-2554.
    • (2000) Microbiology , vol.146 , pp. 2543-2554
    • Macfarlane, E.L.1    Kwasnicka, A.2    Hancock, R.E.W.3
  • 27
    • 0034113773 scopus 로고    scopus 로고
    • Pseudomonas spp. complications in patients with HIV disease: An eight-year clinical and microbiological survey
    • Manfredi, R., A. Nanetti, M. Ferri, and F. Chiodo. 2000. Pseudomonas spp. complications in patients with HIV disease: an eight-year clinical and microbiological survey. Eur. J. Epidemiol. 16:111-118.
    • (2000) Eur. J. Epidemiol , vol.16 , pp. 111-118
    • Manfredi, R.1    Nanetti, A.2    Ferri, M.3    Chiodo, F.4
  • 29
    • 33750582503 scopus 로고    scopus 로고
    • Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen
    • Müh, U., M. Schuster, R. Heim, A. Singh, E. R. Olson, and E. P. Greenberg. 2006. Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen. Antimicrob. Agents Chemother. 50:3674-3679.
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 3674-3679
    • Müh, U.1    Schuster, M.2    Heim, R.3    Singh, A.4    Olson, E.R.5    Greenberg, E.P.6
  • 31
    • 23744495448 scopus 로고    scopus 로고
    • Expression of the psl operon in Pseudomonas aeruginosa PAO1 biofilms: PslA performs an essential function in biofflm formation
    • Overhage, J., M. Schemionek, J. S. Web, and B. H. A. Rehm. 2005. Expression of the psl operon in Pseudomonas aeruginosa PAO1 biofilms: PslA performs an essential function in biofflm formation. Appl. Environ. Microbiol. 71:4407-4413.
    • (2005) Appl. Environ. Microbiol , vol.71 , pp. 4407-4413
    • Overhage, J.1    Schemionek, M.2    Web, J.S.3    Rehm, B.H.A.4
  • 32
    • 33947401483 scopus 로고    scopus 로고
    • Identification of genes involved in swarming motility using a Pseudomonas aeruginosa PAO1 mini-Tn5-lux mutant library
    • Overhage, J., S. Lewenza, A. K. Marr, and R. E. W. Hancock. 2007. Identification of genes involved in swarming motility using a Pseudomonas aeruginosa PAO1 mini-Tn5-lux mutant library. J. Bacteriol. 189:2164-2169.
    • (2007) J. Bacteriol , vol.189 , pp. 2164-2169
    • Overhage, J.1    Lewenza, S.2    Marr, A.K.3    Hancock, R.E.W.4
  • 33
    • 41949114474 scopus 로고    scopus 로고
    • Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance
    • Overhage, J., M. Bains, M. D. Brazas, and R. E. W. Hancock. Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance. J. Bacteriol. 190:2671-2679.
    • J. Bacteriol , vol.190 , pp. 2671-2679
    • Overhage, J.1    Bains, M.2    Brazas, M.D.3    Hancock, R.E.W.4
  • 34
    • 33947155714 scopus 로고    scopus 로고
    • Multiple roles of biosurfactant in structural biofilm development by Pseudomonas aeruginosa
    • Pamp, S. J., and T. Tolker-Nielsen. 2007. Multiple roles of biosurfactant in structural biofilm development by Pseudomonas aeruginosa. J. Bacteriol. 189:2531-2539.
    • (2007) J. Bacteriol , vol.189 , pp. 2531-2539
    • Pamp, S.J.1    Tolker-Nielsen, T.2
  • 36
    • 0037716358 scopus 로고    scopus 로고
    • Pitts, B., M. A. Hamilton, N. Zelver, and P. S. Stewart. 2003. A. microtiter-plate screening method for biofilm disinfection and removal. J. Microbiol. Methods 54:269-276.
    • Pitts, B., M. A. Hamilton, N. Zelver, and P. S. Stewart. 2003. A. microtiter-plate screening method for biofilm disinfection and removal. J. Microbiol. Methods 54:269-276.
  • 37
    • 1042278915 scopus 로고    scopus 로고
    • The relationship between peptide structure and antibacterial activity
    • Powers, J. P., and R. E. W. Hancock. 2003. The relationship between peptide structure and antibacterial activity. Peptides 24:1681-1691.
    • (2003) Peptides , vol.24 , pp. 1681-1691
    • Powers, J.P.1    Hancock, R.E.W.2
  • 38
    • 0037015541 scopus 로고    scopus 로고
    • Biofilms, antimicrobial resistance, and airway infection
    • Prince, A. S. 2002. Biofilms, antimicrobial resistance, and airway infection. N. Engl. J. Med. 347:1110-1111.
    • (2002) N. Engl. J. Med , vol.347 , pp. 1110-1111
    • Prince, A.S.1
  • 40
    • 0036125965 scopus 로고    scopus 로고
    • Pulmonary infections in patients with cystic fibrosis
    • Rajan, S., and L. Saiman. 2002. Pulmonary infections in patients with cystic fibrosis. Semin. Respir. Infect. 17:47-56.
    • (2002) Semin. Respir. Infect , vol.17 , pp. 47-56
    • Rajan, S.1    Saiman, L.2
  • 43
    • 34250969714 scopus 로고
    • Ein Submersver-fahren zur Kultur wasserstoffoxidierender Bakterien: Wachstumsphysiologische Untersuchungen.
    • Schlegel, H. G., H. Kaltwasser, and G. Gottschalk. 1961. Ein Submersver-fahren zur Kultur wasserstoffoxidierender Bakterien: Wachstumsphysiologische Untersuchungen. Arch. Mikrobiol. 38:209-222.
    • (1961) Arch. Mikrobiol , vol.38 , pp. 209-222
    • Schlegel, H.G.1    Kaltwasser, H.2    Gottschalk, G.3
  • 44
    • 0036030617 scopus 로고    scopus 로고
    • Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37
    • Schmidtchen. A., I. M. Frick, E. Andersson, H. Tapper, and L. Björck. 2002. Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37. Mol. Microbiol. 46:157-168.
    • (2002) Mol. Microbiol , vol.46 , pp. 157-168
    • Schmidtchen, A.1    Frick, I.M.2    Andersson, E.3    Tapper, H.4    Björck, L.5
  • 45
    • 0037378570 scopus 로고    scopus 로고
    • Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: A transcriptome analysis
    • Schuster, M., C. P. Lostroh, T. Ogi, and E. P. Greenberg. 2003. Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J. Bacteriol. 185:2066-2079.
    • (2003) J. Bacteriol , vol.185 , pp. 2066-2079
    • Schuster, M.1    Lostroh, C.P.2    Ogi, T.3    Greenberg, E.P.4
  • 47
    • 33750582837 scopus 로고    scopus 로고
    • The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional
    • Shrout, J. D., D. L. Chopp, C. L. Just, M. Hentzer, M. Givskov, and M. R. Parsek. 2006. The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Mol. Microbiol. 62:1264-1277.
    • (2006) Mol. Microbiol , vol.62 , pp. 1264-1277
    • Shrout, J.D.1    Chopp, D.L.2    Just, C.L.3    Hentzer, M.4    Givskov, M.5    Parsek, M.R.6
  • 48
    • 0034641962 scopus 로고    scopus 로고
    • Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
    • Singh, P. K., A. L. Scbaefer, M. R. Parsek, T. O. Moninger, M. J. Welsh, and E. P. Greenberg. 2000. Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature 407:762-764.
    • (2000) Nature , vol.407 , pp. 762-764
    • Singh, P.K.1    Scbaefer, A.L.2    Parsek, M.R.3    Moninger, T.O.4    Welsh, M.J.5    Greenberg, E.P.6
  • 49
    • 0037198693 scopus 로고    scopus 로고
    • Singh, P. K., M. R. Parsek, E. P. Greenberg, and M. J. Welsh. 2002. A. component of innate immunity prevents bacterial biofilm development. Nature 417:552-555.
    • Singh, P. K., M. R. Parsek, E. P. Greenberg, and M. J. Welsh. 2002. A. component of innate immunity prevents bacterial biofilm development. Nature 417:552-555.
  • 50
    • 0035859467 scopus 로고    scopus 로고
    • Antibiotic resistance of bacteria in biofilms
    • Stewart, P. S., and J. W. Costerton. 2001. Antibiotic resistance of bacteria in biofilms. Lancet 358:135-138.
    • (2001) Lancet , vol.358 , pp. 135-138
    • Stewart, P.S.1    Costerton, J.W.2
  • 51
    • 0034739007 scopus 로고    scopus 로고
    • Stover, C. K., X. Q. Pham, A. L. Erwin, S. D. Mizoguchi, P. Warrener, M. J. Hickey, F. S. L. Brinkman, W. O. Hufnagle, D. J. Kowslik, M. Lagrou, R. L. Garber, L. Goltry, E. Tolentino, S. Westbrock-Wadman, Y. Yuan, U L. Brody. S. N. Coulter, K. R. Folger, A. Kas, K. Larbig, R. Um, K. Smith, D. Spencer, G. K.-S. Wong, Z. Wu, I. T. Paulsen, J. Reizer, M. H. Saier, R. E. W. Hancock, S. Lory, and M. V. Olson. 2000. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature 406:959-964.
    • Stover, C. K., X. Q. Pham, A. L. Erwin, S. D. Mizoguchi, P. Warrener, M. J. Hickey, F. S. L. Brinkman, W. O. Hufnagle, D. J. Kowslik, M. Lagrou, R. L. Garber, L. Goltry, E. Tolentino, S. Westbrock-Wadman, Y. Yuan, U L. Brody. S. N. Coulter, K. R. Folger, A. Kas, K. Larbig, R. Um, K. Smith, D. Spencer, G. K.-S. Wong, Z. Wu, I. T. Paulsen, J. Reizer, M. H. Saier, R. E. W. Hancock, S. Lory, and M. V. Olson. 2000. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature 406:959-964.
  • 53
    • 0346996865 scopus 로고    scopus 로고
    • The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor
    • Tjabringa, G. S., J. Aarbiou, D. K. Ninaber, J. W. Drijfhout, O. E. Sørensen, N. Borregaard, K. F. Rabe, and P. S. Hiemstra. 2003. The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor. J. Immunol. 171: 6690-6696.
    • (2003) J. Immunol , vol.171 , pp. 6690-6696
    • Tjabringa, G.S.1    Aarbiou, J.2    Ninaber, D.K.3    Drijfhout, J.W.4    Sørensen, O.E.5    Borregaard, N.6    Rabe, K.F.7    Hiemstra, P.S.8
  • 54
    • 0037377827 scopus 로고    scopus 로고
    • Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: Effects of growth phase and environment
    • Wagner, V. E., D. Bushnell, L. Passador, A. I. Brooks, and B. H. Iglewski. 2003. Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment. J. Bacteriol. 185:2080-2095.
    • (2003) J. Bacteriol , vol.185 , pp. 2080-2095
    • Wagner, V.E.1    Bushnell, D.2    Passador, L.3    Brooks, A.I.4    Iglewski, B.H.5
  • 55
    • 0032907969 scopus 로고    scopus 로고
    • Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide
    • Wu, M., and R. E. W. Hancock. 1999. Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob. Agents Chemother. 43:1274-1276.
    • (1999) Antimicrob. Agents Chemother , vol.43 , pp. 1274-1276
    • Wu, M.1    Hancock, R.E.W.2
  • 56
    • 0035032985 scopus 로고    scopus 로고
    • Synergistic interactions between mammalian antimicrobial defense peptides
    • Yan, H., and R. E. W. Hancock. 2001. Synergistic interactions between mammalian antimicrobial defense peptides. Antimicrob. Agents Chemother. 45:1558-1560.
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 1558-1560
    • Yan, H.1    Hancock, R.E.W.2


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