Production of Medium Chain Fatty Acids by Yarrowia lipolytica: Combining Molecular Design and TALEN to Engineer the Fatty Acid Synthase

ACS Synthetic Biology

Volumn 6, Issue 10, 2017, Pages 1870-1879

  Rigouin, Coraline ^a   Gueroult, Marc ^a   Croux, Christian ^a   Dubois, Gwendoline ^a   Borsenberger, Vinciane ^a   Barbe, Sophie ^a   Marty, Alain ^a   Daboussi, Fayza ^a   André, Isabelle ^a   Bordes, Florence ^a  

^a INSA   (France)

Author keywords

biofuel; computer aided engineering; fatty acid synthase; ketoacyl synthase specificity; medium chain fatty acid; TALEN; Yarrowia lipolytica

Indexed keywords

AROMATIC AMINO ACID; FATTY ACID SYNTHASE; FUNGAL ENZYME; ISOLEUCINE; MEDIUM CHAIN FATTY ACID; PALMITIC ACID; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; FATTY ACID;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; BIOTECHNOLOGICAL PRODUCTION; CARBOXY TERMINAL SEQUENCE; COMPUTER AIDED DESIGN; CONTROLLED STUDY; DNA END JOINING REPAIR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ENGINEERING; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME SYNTHESIS; FUNGAL GENOME; GENE EDITING; HOMOLOGOUS RECOMBINATION; LIPOGENESIS; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SYNTHETIC BIOLOGY; YARROWIA LIPOLYTICA; ENZYMOLOGY; GENETICS; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL; YARROWIA;

BIOLOGICAL TRANSPORT; FATTY ACID SYNTHASES; FATTY ACIDS; TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES; YARROWIA;

EID: 85031932149     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.7b00034     Document Type: Article

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