Structural Snapshots of α-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases

Angewandte Chemie - International Edition

Volumn 56, Issue 47, 2017, Pages 14853-14857

  Albesa Jové, David ^a   Sainz Polo, M Ángela ^a   Marina, Alberto ^a   Guerin, Marcelo E ^a  

^a CIC BIOGUNE   (Spain)

Author keywords

enzyme catalysis; enzymes; glycosyltransferases; reaction mechanisms; structural biology

Indexed keywords

BIOLOGY; CATALYSIS; QUANTUM CHEMISTRY; SUBSTRATES;

ANOMERIC CONFIGURATION; DOUBLE-DISPLACEMENT MECHANISMS; ENZYME CATALYSIS; EXPERIMENTAL EVIDENCE; GLYCOSYLTRANSFERASES; REACTION MECHANISM; RETAINING GLYCOSYLTRANSFERASES; STRUCTURAL BIOLOGY;

ENZYMES;

DIVALENT CATION; GALACTOSYLTRANSFERASE; GLYCOSYLTRANSFERASE; LACTOSE;

ANIMAL; BOVINE; CATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; METABOLISM; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; CATALYSIS; CATALYTIC DOMAIN; CATIONS, DIVALENT; CATTLE; CRYSTALLOGRAPHY, X-RAY; GALACTOSYLTRANSFERASES; GLYCOSYLTRANSFERASES; LACTOSE; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 85031726299     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201707922     Document Type: Article

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