Caffeic Acid Phenethyl Ester (Propolis Extract) Ameliorates Insulin Resistance by Inhibiting JNK and NF-κB Inflammatory Pathways in Diabetic Mice and HepG2 Cell Models

Journal of Agricultural and Food Chemistry

Volumn 65, Issue 41, 2017, Pages 9041-9053

  Nie, Jiarui ^a   Chang, Yaning ^a   Li, Yujia ^a   Zhou, Yingjun ^a   Qin, Jiawen ^a   Sun, Zhen ^a   Li, Haibin ^b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Bee Forest Industry Co LTD   (China)

Author keywords

caffeic acid phenethyl ester; inflammation; insulin resistance; JNK; NF B

Indexed keywords

CELL SIGNALING; CELLS; CYTOLOGY; ESTERS; GLUCOSE; MAMMALS;

CAFFEIC ACID PHENETHYL ESTER; INFLAMMATION; INSULIN RESISTANCE; INSULIN-DEPENDENT DIABETES MELLITUS; NUCLEAR TRANSLOCATIONS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PRO-INFLAMMATORY CYTOKINES; TUMOR NECROSIS FACTOR ALPHA;

INSULIN;

CAFFEIC ACID DERIVATIVE; CAFFEIC ACID PHENETHYL ESTER; GLUCOSE 6 PHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHENETHYL ALCOHOL; PROPOLIS;

ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; GENETICS; HEP-G2 CELL LINE; HUMAN; IMMUNOLOGY; INSULIN RESISTANCE; MALE; METABOLISM; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; SIGNAL TRANSDUCTION;

ANIMALS; CAFFEIC ACIDS; DIABETES MELLITUS, TYPE 2; GLUCOSE-6-PHOSPHATASE; HEP G2 CELLS; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MAP KINASE KINASE 4; MICE; MICE, INBRED C57BL; NF-KAPPA B; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PHENYLETHYL ALCOHOL; PROPOLIS; SIGNAL TRANSDUCTION;

EID: 85031698742     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.7b02880     Document Type: Article

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