Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver

Journal of Biochemical and Molecular Toxicology

Volumn 18, Issue 4, 2004, Pages 234-238

  Ramazan Yilmaz, H ^a   Uz, Efkan ^a   Yucel, Nezahat ^a   Altuntas, Irfan ^b   Ozcelik, Nurten ^a  

^a SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b SULEYMAN DEMIREL UNIVERSITY   (Turkey)

Author keywords

Antioxidant enzymes; Caffeic acid phenethyl ester; Diabetes; Lipid peroxidation

Indexed keywords

ANTIOXIDANT; CAFFEIC ACID PHENETHYL ESTER; CATALASE; GLUTATHIONE PEROXIDASE; LIPID; MALONALDEHYDE; STREPTOZOCIN; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DOSE REGIMEN; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER INJURY; LIVER LEVEL; LIVER PROTECTION; MALE; NONHUMAN; RANDOMIZATION; RAT; STATISTICAL SIGNIFICANCE; STREPTOZOCIN DIABETES; TREATMENT OUTCOME;

ANIMALS; ANTIOXIDANTS; CAFFEIC ACIDS; CATALASE; DIABETES MELLITUS, EXPERIMENTAL; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; PHENYLETHYL ALCOHOL; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE;

FELIS CATUS;

EID: 5044245855     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.20028     Document Type: Article

References (47)

1. Ceriello A. Oxidative stress and glycemic regulation. Metabolism 2000;49:27-29.
2. Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications: A new perspective on an old paradigm. Diabetes 1999;48:1-9.
3. Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes 1991;40:405-412.
4. Young IS, Tate S, Lightbody JH, McMaster D, Trimble ER. The effects of desferrioxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat. Free Radical Biol Med 1995;18:833-840.
5. Hunt JV, Smith CC, Wolff SP. Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 1990;39:1420-1424.
6. Wolff SP. Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications. Br Med Bull 1993;49:642-652.
7. Saxena AK, Srivastava P, Kale RK, Baquer NZ. Impaired antioxidant status in diabetic rat liver. Effect of vanadate. Biochem Pharmacol 1993;45:539-542.
8. McLennan SV, Heffernan S, Wright L, Rae C, Fisher E, Yue DK, Turtle JR. Changes in hepatic glutathione metabolism in diabetes. Diabetes 1991;40:344-348.
9. Ilhan A, Koltuksuz U, Ozen S, Uz E, Ciralik H, Akyol O. The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits. Eur J Cardiothorac Surg 1999;16:458-463.
10. Rao C, Desai D, Kaul B, Amin S, Reddy BS. Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth. Chem Biol Interact 1992;84:277-290.
11. Sud'ina GF, Mirzoeva OK, Pushkareva GA, Korshunova GA, Sumbatyan NV, Varfolomeev SD. Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties. FEBS Lett 1993;329:21-24.
12. Michaluart P, Masferrer JL, Carothers AM, Subbaramaiah K, Zweifel BS, Koboldt C, Mestre JR, Grunberger D, Sacks PG, Tanabe T, Dannenberg AJ. Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation. Cancer Res 1999;59:2347-2352.
13. Chen YJ, Shiao MS, Wang SY. The antioxidant caffeic acid phenethyl ester induces apoptosis associated with selective scavenging of hydrogen peroxide in human leukemic HL-60 cells. Anticancer Drugs 2001;12:143-149.
14. Fesen MR, Pommier Y, Leteurtre E, Hiroguchi S, Yung J, Kohn KW. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem Pharmacol 1994;48:595-608.
15. Park EH and Kahng JH. Suppressive effects of propolis in rat adjuvant arthritis. Arch Pharm Res 1999;22:554-558.
16. Yildirim O, Buyukbingol. Effect of cobalt on the oxidative status in heart and aorta of streptozotocin-induced diabetic rats. Cell Biochem Funct 2003;21:27-33.
17. Aksoy N, Vural H, Sabuncu T, Aksoy S. Effects of melatonin on oxidative-antioxidative status of tissues in streptozotocin-induced diabetic rats. Cell Biochem Funct 2003;21:121-125.
18. Zobali F, Avci A, Canbolat O, Karasu C. Effects of vitamin A and insulin on the antioxidative state of diabetic rat heart: a comparison study with combination treatment. Cell Biochem Fund 2002;20:75-80.
19. Vural H, Sabuncu T, Arslan SO, Aksoy N. Melatonin inhibits lipid peroxidation and stimulates the antioxidant status of diabetic rats. J Pineal Res 2001;31:193-198.
20. Aliciguzel Y, Ozen I, Aslan M, Karayalcin U. Activities of xanthine oxidoreductase and antioxidant enzymes in different tissues of diabetic rats. J Lab Clin Med 2003;142:172-177.
21. Cho SY, Park JY, Park EM, Choi MS, Lee MK, Jeon SM, Jang MK, Kim MJ, Park YB. Alternation of hepatic antioxidant enzyme activities and lipid profile in streptozotocin-induced diabetic rats by supplementation of dandelion water extract. Clin Chim Acta 2002;317:109-117.
22. Baydas G, Canatan H, Turkoglu A. Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus. J Pineal Res 2002;32:225-230.
23. Hunkar T, Aktan F, Ceylan A, Karasu C. Effects of cod liver oil on tissue antioxidant pathways in normal and streptozotocin-diabetic rats. Cell Biochem Funct 2002;20:297-302.
24. Hepsen IF, Er H, Cekic O. Topically applied water extract of propolis to suppress corneal neovascularization in rabbits. Ophthalmic Res 1999;31:426-431.
25. Gurel A, Armutcu F, Sahin S, Sogut S, Ozyurt H, Gulec M, Kutlu NO, Akyol O. Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys. Clin Chim Acta 2004;339:33-41.
26. Uz E, Sogut S, Sahin S, Var A, Özyurt H, Gulec M, Akyol O. The protective role of caffeic acid phenethyl ester (CAPE) on testicular tissue after testicular torsion and detorsion. World J Urol 2002;20:264-270.
27. Lowry OH, Rosebrough NJ, Farr AL. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
28. Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 1990;86:421-431.
29. Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988;34:497-500.
30. Durak I, Yurtarslani Z, Canbolat O, Akyol O. A methodological approach to superoxide dismutase (SOD) activity assay based on inhibition of nitroblue tetrazolium (NBT) reduction. Clin Chim Acta 1993;214:103-104.
31. Aebi Y. Catalase in vitro. Methods Enzymol. 1984:105:121-126.
32. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-170.
33. Giugliano D, Ceriello A, Paolisso G. Diabetes mellitus, hypertension, and cardiovascular disease: which role for oxidative stress? Metabolism 1995;44:363-368.
34. Kaul N, Siveski-Iliskovic N, Hill M, Khaper N, Seneviratne C, Singal PK. Probucol treatment reverses antioxidant and functional deficit in diabetic cardiomyopathy. Mol Cell Biochem 1996;160/161:283-288.
35. Ozkaya YG, Agar A, Yargicoglu P, Hacioglu G, Bilmen-Sarikcioglu S, Ozen I, Aliciguzel Y. The effect of exercise on brain antioxidant status of diabetic rats. Diabetes Metab 2002;28:377-384.
36. Wohaieb SA, Godin DV. Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment. Diabetes 1987;36:1014-1018.
37. Huang WC, Juang SW, Liu IM, Chi TC, Cheng JT. Changes of superoxide dismutase gene expression and activity in the brain of streptozotocin-induced diabetic rats. Neurosci Lett 1999;275:25-28.
38. Pieper GM, Jordan M, Dondlinger LA, Adams MB, Roza AM. Peroxidative stress in diabetic blood vessels. Reversal by pancreatic islet transplantation. Diabetes 1995;44:884-889.
39. Kakkar R, Kalra J, Mantha SV, Prasad K. Lipid peroxidation and activity of antioxidant enzymes in diabetic rats. Mol Cell Biochem 1995;151:113-119.
40. Tatsuki R, Satoh K, Yamamoto A, Hoshi K, Ichihara K. Lipid peroxidation in the pancreas and other organs in streptozotocin diabetic rats. Jpn J Pharmacol 1997;75:267-273.
41. Sies H. Damage to plasmid DNA by singlet oxygen and its protection. Mutat Res 1993;299:183-191.
42. Santini SA, Marra G, Giardina B, Cotroneo P, Mordente A, Martorana GE, Manto A, Ghirlanda G. Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM. Diabetes 1997;46:1853-1858.
43. Buyukokuroglu ME, Taysi S, Koc M, Bakan N. Dantrolene protects erythrocytes against oxidative stress during whole-body irradiation in rats. Cell Biochem Funct 2003;21:127-131.
44. Rauscher FM, Sanders RA, Watkins JB III. Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 2001a;15:41-46.
45. Rauscher FM, Sanders RA, Watkins JB III. Effects of isoeugenol on oxidative stress pathways in normal and streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 2001b;15:159-164.
46. Rauscher FM, Sanders RA, Watkins JB III. Effects of new antioxidant compounds PNU-104067F and PNU-74389G on antioxidant defense in normal and diabetic rats. J Biochem Mol Toxicol 2000a;14:189-194.
47. Rauscher FM, Sanders RA, Watkins JB III. Effects of piperine on antioxidant pathways in tissues from normal and streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 2000b;14:329-334.