RNA targeting with CRISPR-Cas13

Nature

Volumn 550, Issue 7675, 2017, Pages 280-284

  Abudayyeh, Omar O ^a,b,c,d   Gootenberg, Jonathan S ^a,b,c,d,e   Essletzbichler, Patrick ^a,b,c,d   Han, Shuo ^f   Joung, Julia ^a,b,c,d   Belanto, Joseph J ^g,h   Verdine, Vanessa ^a,b,c,d   Cox, David B T ^a,b,c,d   Kellner, Max J ^a   Regev, Aviv ^a,c   Lander, Eric S ^a,c,e   Voytas, Daniel F ^g,h   Ting, Alice Y ^f   Zhang, Feng ^a,b,c,d  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f STANFORD UNIVERSITY   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

^h UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; CRISPR ASSOCIATED PROTEIN;

ASSAY; BACTERIUM; CELLS AND CELL COMPONENTS; COLIFORM BACTERIUM; PROTEIN; RNA; TRACKING;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; CRISPR CAS13A SYSTEM; ESCHERICHIA COLI; GENE SILENCING; GENE TARGETING; GENETIC TRANSCRIPTION; HETEROLOGOUS EXPRESSION; LEPTOTRICHIA; LEPTOTRICHIA WADEI; MAMMAL CELL; NONHUMAN; PLANT CELL; PRIORITY JOURNAL; REPORTER GENE; RNA BINDING; RNA INTERFERENCE; BIOCATALYSIS; CELL SURVIVAL; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENE EDITING; GENE KNOCKDOWN; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PHYSIOLOGICAL STRESS; PROCEDURES; TUMOR CELL LINE;

ESCHERICHIA COLI; LEPTOTRICHIA WADEII; MAMMALIA;

BIOCATALYSIS; CELL LINE, TUMOR; CELL SURVIVAL; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; ESCHERICHIA COLI; GENE EDITING; GENE KNOCKDOWN TECHNIQUES; GENES, REPORTER; HEK293 CELLS; HUMANS; LEPTOTRICHIA; PLANT CELLS; RNA; RNA INTERFERENCE; STRESS, PHYSIOLOGICAL; SUBSTRATE SPECIFICITY;

EID: 85031303757     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature24049     Document Type: Article

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