Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

Cell Reports

Volumn 21, Issue 2, 2017, Pages 366-380

  Mathys, Hansruedi ^a   Adaikkan, Chinnakkaruppan ^a   Gao, Fan ^a   Young, Jennie Z ^a   Manet, Elodie ^a   Hemberg, Martin ^b   De Jager, Philip L ^c,e   Ransohoff, Richard M ^d   Regev, Aviv ^a,e   Tsai, Li Huei ^a,e  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c NewYork Presbyterian Hospital   (United States)

^d Broad Institute of MIT and Harvard ^*  (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

Alzheimer's disease; microglia; neurodegeneration; single cell RNA sequencing

Indexed keywords

GAMMA INTERFERON; INTERFERON; RNA; TRANSCRIPTOME;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL HETEROGENEITY; CELL REPROGRAMMING TECHNIQUE; CELL TRACKING; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; HIPPOCAMPUS; MICROGLIA; MOUSE; NERVE DEGENERATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; SINGLE CELL ANALYSIS; ANIMAL; BRAIN; CELL CULTURE; CYTOLOGY; GENE EXPRESSION PROFILING; GENETICS; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM;

ALZHEIMER DISEASE; ANIMALS; BRAIN; CELLS, CULTURED; GENE EXPRESSION PROFILING; INTERFERON TYPE I; INTERFERON-GAMMA; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICROGLIA; PHENOTYPE; SINGLE-CELL ANALYSIS; TRANSCRIPTOME;

EID: 85030862421     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.09.039     Document Type: Article

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