Type 1 diabetes induction in humanized mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 41, 2017, Pages 10954-10959

  Tan, Shulian ^a,b,c   Li, Yang ^a,b,c   Xia, Jinxing ^c   Jin, Chun Hui ^a,c   Hu, Zheng ^a,b   Duinkerken, Gaby ^d   Li, Yuying ^a,c   Khosravi Maharlooei, Mohsen ^c   Chavez, Estefania ^c   Nauman, Grace ^c   Danzl, Nichole ^c   Nakayama, Maki ^e   Roep, Bart O ^d,f   Sykes, Megan ^c   Yang, Yong Guang ^a,b,c  

^a JILIN UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

^c Leiden University Medical Center ^*  (United States)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^f CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Humanized mice; Insulin; Type 1 diabetes

Indexed keywords

COMPLEMENTARY DNA; HLA DQ8 ANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; AUTOANTIGEN; HLA DQ ANTIGEN; INSULIN; INSULIN B (9-23); PEPTIDE FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL TRANSPLANTATION; GRAFT VERSUS HOST REACTION; HYPERGLYCEMIA; IMMUNOPATHOGENESIS; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; TRANSGENIC MOUSE; XENOGENEIC GRAFT VERSUS HOST REACTIVITY; ANIMAL; AUTOIMMUNITY; CELL CULTURE; EXPERIMENTAL DIABETES MELLITUS; GENETICS; HUMAN; IMMUNOLOGY; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PATHOLOGY; SCID MOUSE;

ANIMALS; AUTOANTIGENS; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; HLA-DQ ANTIGENS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, INBRED NOD; MICE, SCID; MICE, TRANSGENIC; PEPTIDE FRAGMENTS;

EID: 85030766826     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1710415114     Document Type: Article

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