Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation

Journal of Immunology

Volumn 187, Issue 11, 2011, Pages 5921-5930

  Michels, Aaron W ^a   Ostrov, David A ^b   Zhang, Li ^a   Nakayama, Maki ^a   Fuse, Masanori ^a   McDaniel, Kristen ^a   Roep, Bart O ^c   Gottlieb, Peter A ^a   Atkinson, Mark A ^b   Eisenbarth, George S ^a  

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AUTOANTIGEN; CHEMICAL COMPOUND; GLYPHOSINE; GLYPHOSINE DERIVATIVE; INSULIN; INSULIN B:9 23; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE; SMALL MOLECULE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ARTICLE; BINDING SITE; CELLULAR IMMUNITY; CHILD; COMPUTER MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DIABETES MELLITUS; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; MALE; MOLECULAR DOCKING; MOLECULAR LIBRARY; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PRIORITY JOURNAL; SCHOOL CHILD; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION;

ALLELES; ANIMALS; ANTIGEN PRESENTATION; AUTOANTIGENS; DIABETES MELLITUS, TYPE 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCINE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; INSULIN; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED NOD; MODELS, MOLECULAR; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 82755162147     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100746     Document Type: Article

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