Non-oxidizable HMGB1 induces cardiac fibroblasts migration via CXCR4 in a CXCL12-independent manner and worsens tissue remodeling after myocardial infarction

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1863, Issue 11, 2017, Pages 2693-2704

  Di Maggio, Stefania ^a   Milano, Giuseppina ^a,b   De Marchis, Francesco ^c   D'Ambrosio, Alessandro ^a   Bertolotti, Matteo ^a   Palacios, Blanca Soler ^d   Badi, Ileana ^a   Sommariva, Elena ^a   Pompilio, Giulio ^a,e   Capogrossi, Maurizio C ^f   Raucci, Angela ^a  

^a CENTRO CARDIOLOGICO MONZINO   (Italy)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^e UNIVERSITY OF MILAN   (Italy)

^f LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

Author keywords

Cardiac fibroblasts; Cardiac remodeling; CXCR4; Myocardial infarction; Oxidation

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CHEMOKINE RECEPTOR CXCR4; HIGH MOBILITY GROUP B1 PROTEIN; PLERIXAFOR; PROTEIN TYROSINE KINASE; TOLL LIKE RECEPTOR 4; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; HMGB1 PROTEIN, HUMAN; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; FEMALE; HEART FIBROBLAST; HEART INFARCTION; HEART PERFORMANCE; HEART VENTRICLE REMODELING; HUMAN; HUMAN CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; CARDIAC MUSCLE; CELL MOTION; FIBROBLAST; MALE; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY;

CELL MOVEMENT; CHEMOKINE CXCL12; FEMALE; FIBROBLASTS; HMGB1 PROTEIN; HUMANS; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; OXIDATION-REDUCTION; RECEPTORS, CXCR4;

EID: 85030658256     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2017.07.012     Document Type: Article

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