How to survive the medical misinformation mess

European Journal of Clinical Investigation

Volumn 47, Issue 11, 2017, Pages 795-802

  Ioannidis, John P A ^a,b   Stuart, Michael E ^c,d   Brownlee, Shannon ^e,f   Strite, Sheri A ^d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d Delfini Group   (United States)

^e Lown Cardiovascular Group   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COMMUNICATION SKILL; EVIDENCE BASED MEDICINE; FAMILY; HEALTH CARE PERSONNEL; HEALTH CARE POLICY; HUMAN; MEDICAL DECISION MAKING; MEDICAL INFORMATION; MEDICAL MISINFORMATION MESS; MEDICAL RESEARCH; META ANALYSIS (TOPIC); PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RELIABILITY; SKILL; SYSTEMATIC REVIEW (TOPIC); CLINICAL DECISION MAKING; FORECASTING; MEASUREMENT ACCURACY; METHODOLOGY; PROFESSIONAL COMPETENCE; PUBLICATION; STANDARDS; STATISTICS AND NUMERICAL DATA;

BIOMEDICAL RESEARCH; CLINICAL DECISION-MAKING; DATA ACCURACY; EVIDENCE-BASED MEDICINE; FORECASTING; HEALTH PERSONNEL; HUMANS; PERIODICALS AS TOPIC; PROFESSIONAL COMPETENCE; PUBLICATIONS; RESEARCH DESIGN;

EID: 85030630165     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/eci.12834     Document Type: Article

References (60)

1. PubMed search terms: “humans;” “humans” with Clinical Trial article type; “humans” with Review article type; “humans” with Systematic Reviews article type. PubMed database. Available at: https://www.ncbi.nlm.nih.gov/pubmed. Accessed on 13 February 2017.
2. Ioannidis JP. Why most published research findings are false. PLoS Med 2005;2:e124.
3. Ioannidis JP. The mass production of redundant, misleading, and conflicted systematic reviews and meta-analyses. Milbank Q 2016;94:485–514. https://doi.org/10.1111/1468-0009.12210.
4. Lenzer J, Hoffman JR, Furberg CD, Ioannidis JP; Guideline Panel Review Working Group. Ensuring the integrity of clinical practice guidelines: a tool for protecting patients. BMJ. 2013;347:f5535.
5. Schwitzer G. A guide to reading health care news stories. JAMA Intern Med 2014;174:1183–6.
6. Chassin MR, Galvin RW; the National Roundtable on Health Care Quality. The urgent need to improve quality: Institute of Medicine National Roundtable on Health Care Quality [consensus statement]. JAMA 1998;280:1000–5.
7. Kerr EA, McGlynn EA, Adams J, Keesey J, Asch SM. Profiling the quality of care in twelve communities: results from the CQI study. Health Aff (Millwood) 2004;23:247–56.
8. McGlynn EA, Asch SM, Adams J, Keesey J, Hicks J, DeCristofaro A et al. The quality of health care delivered to adults in the United States. N Engl J Med 2003;348:2635–45.
9. Skinner J, Fisher ES, Wennberg JE. For the National Bureau of Economic Research. The efficiency of Medicare. Working Paper No. 8395. Cambridge, MA: National Bureau of Economic Research; July 2001.
10. Olsen LA, Saunders RS, Yong PL, eds. The Healthcare Imperative: Lowering Costs and Improving Outcomes: Workshop Series Summary. Washington, DC: National Academies Press; 2010.
11. Brownlee S, Chalkidou K, Doust J, Elshaug AG, Glasziou P, Heath I et al. Evidence for overuse of medical services around the world. Lancet 2017;390:156–68.
12. Saini V, Brownlee S, Elshaug AG, Glasziou P, Heath I. Addressing overuse and underuse around the world. Lancet 2017;390:105–7.
13. Glasziou P, Straus S, Brownlee S, Trevena L, Dans L, Guyatt G et al. Evidence for underuse of effective medical services around the world. Lancet 2017;390:169–77. pii: S0140-6736(16)30946-1. https://doi.org/10.1016/s0140-6736(16)30946-1
14. Guyatt GH, Meade MO, Jaeschke RZ, Cook DJ, Haynes RB. Practitioners of evidence based care. Not all clinicians need to appraise evidence from scratch but all need some skills. BMJ 2000;320:954–5.
15. Ioannidis JP. Why most clinical research is not useful. PLoS Med 2016;13:e1002049. https://doi.org/10.1371/journal.pmed.1002049.
16. McKibbon KA, Wilczynski NL, Haynes RB. What do evidence-based secondary journals tell us about the publication of clinically important articles in primary healthcare journals? BMC Med 2004;2:33.
17. Glasziou P. The EBM journal selection process: how to find the 1 in 400 valid and highly relevant new research articles. Evid Based Med 2006;11:101.
18. Ioannidis JP. How to make more published research true. PLoS Med 2014;11:e1001747. https://doi.org/10.1371/journal.pmed.1001747.
19. Munafò MR, Nosek BA, Bishop DVM, Button KS, Chambers CD, du Sert NP et al. A manifesto for reproducible science. Nat Hum Behav 2017;1:0021. https://doi.org/10.1038/s41562-016-0021.
20. Saint S, Christakis DA, Saha S, Elmore JG, Welsh DE, Baker P et al. Journal reading habits of internists. J Gen Intern Med 2000;15:881–4.
21. Hopewell S, Boutron I, Altman DG, Barbour G, Moher D, Montori V et al. Impact of a web-based tool (WebCONSORT) to improve the reporting of randomised trials: results of a randomised controlled trial. BMC Med 2016;14:199.
22. Vera-Badillo FE, Napoleone M, Krzyzanowska MK, Alibhai SM, Chan AW, Ocana A et al. Bias in reporting of randomized clinical trials in oncology. Eur J Cancer 2016;61:29–35. https://doi.org/10.1016/j.ejca.2016.03.066.
23. Shaneyfelt T. In guidelines we cannot trust. Arch Intern Med 2012;172:1633–4.
24. Kung J, Miller RR, Mackowiak PA. Failure of clinical practice guidelines to meet Institute of Medicine standards: two more decades of little, if any, progress. Arch Intern Med 2012;172:1628–33.
25. Program pre-test scores: “Using the Medical Literature”. June 6, 2003. Available at: http://www.delfini.org/Delfini_Pre-Test_Report_0306.pdf. Accessed on 1 February 2017.
26. Fritsche L, Greenhalgh T, Falck-Ytter Y, Neumayer HH, Kunz R. Do short courses in evidence based medicine improve knowledge and skills? Validation of Berlin questionnaire and before and after study of courses in evidence based medicine. BMJ 2002;7:1338–41.
27. James MJ, Cook-Johnson RJ, Cleland LG. Selective COX-2 inhibitors, eicosanoid synthesis and clinical outcomes: a case study of system failure. Lipids 2007;42:779–85.
28. Smith AB, Semler L, Rehman EA, Haddad ZG, Ahmadzadeh KL, Crellin SJ et al. A cross-sectional study of medical student knowledge of evidence-based medicine as measured by the Fresno Test. J Emerg Med 2016;. https://doi.org/10.1016/jemermed.2016.02.006.
29. Young T, Rohwer A, Volmink J, Clarke M. What are the effects of teaching evidence-based health care (EBHC)? Overview of systematic reviews. PLoS ONE 2014;9:e86706. https://doi.org/10.1371/journal.pone.0086706.
30. Flores-Mateo G, Argimon JM. Evidence based practice in postgraduate healthcare education: a systematic review. BMC Health Serv Res 2007;7:119.
31. Hecht L, Buhse S, Meyer G. Effectiveness of training in evidence-based medicine skills for healthcare professionals: a systematic review. BMC Med Educ 2016;16:103. https://doi.org/10.1186/s12909-016-0616-2.
32. Horsley T, Hyde C, Santesso N, Parkes J, Milne R, Stewart R. Teaching critical appraisal skills in healthcare settings. Cochrane Database Syst Rev 2011;(11):CD001270. https://doi.org/10.1002/14651858.cd001270.pub2.
33. Linzer M, Brown JT, Frazier LM, DeLong ER, Siegel WC. Impact of a medical journal club on house-staff reading habits, knowledge, and critical appraisal skills. A randomized control trial. JAMA 1988;260:2537–41.
34. MacRae HM, Regehr G, McKenzie M, Henteleff H, Taylor M, Barkun J et al. Teaching practicing surgeons critical appraisal skills with an Internet-based journal club: a randomized, controlled trial. Surgery 2004;136:641–6.
35. Taylor RS, Reeves BC, Ewings PE, Taylor RJ. Critical appraisal skills training for health care professionals: a randomized controlled trial. BMC Med Educ 2004;4:30.
36. Higgins JPT, Altman DG (editors). Chapter 8: assessing risk of bias in included studies. In: Higgins JPT, Green S, editors. Cochrane Handbook of Systematic Reviews of Interventions Version 5.1.0 [updated March 2011], The Cochrane Collaboration. Available at: www.cochranehandbook.org. Accessed on 10 June 2017.
37. Schwitzer G. Pollution of health news: time to drain the swamp. BMJ 2017;356:j1262.
38. Walsh-Childers K, Braddock J, Rabaza C, Schwitzer G. One step forward, one step back: changes in news coverage of medical interventions. Health Commun 2016:1–14. https://doi.org/10.1080/10410236.2016.1250706.
39. Schwitzer G. Trying to drink from a fire hose: too much of the wrong kind of health care news. Trends Pharmacol Sci 2015;36:623–7.
40. Schwitzer G. How can journalists do a better job reporting on the principles of shared decision making? Chapter 41. In: Elwyn G, Edwards A, Thompson R, editors. Shared Decision Making in Health Care: Achieving Evidence-Based Patient Choice, 3rd edn. Oxford: Oxford University Press; 2016: 270–6.
41. Mulley AG, Trimble C, Elwyn G. Stop the silent misdiagnosis: patients’ preferences matter. BMJ 2012;345:e6572. https://doi.org/10.1136/bmj.e6572.
42. King JS, Moulton BW. Rethinking informed consent: the case for shared medical decision-making. Am J Law Med 2006;32:429–501.
43. Makoul G, Clayman ML. An integrative model of shared decision-making in medical encounters. Patient Educ Couns 2006;60:301–12.
44. Elwyn G, Frosch D, Thomson R, Joseph-Williams N, Lloyd A, Kinnersley P et al. Shared decision-making: a model for clinical practice. J Gen Intern Med 2012;27:1361–7.
45. Stacey D, Légaré F, Col NF, Bennett CL, Barry MJ, Eden KB et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev 2014;(1). Art. No.: CD001431. https://doi.org/10.1002/14651858.cd001431.pub4.
46. Montori VM, LeBlanc A, Buchholz A, Stilwell DL, Tsapas A. Basing information on comprehensive, critically appraised, and up-to-date syntheses of the scientific evidence: a quality dimension of the International Patient Decision Aid Standards. BMC Med Inform Decis Mak 2013;13(Suppl 2):S5. https://doi.org/10.1186/1472-6947-13-S2-S5.
47. Elwyn G, Scholl I, Tietbohl C, Mann M, Edwards AGK, Clay C et al. “Many miles to go …”: a systematic review of the implementation of patient decision support interventions into routine clinical practice. BMC Med Inform Decis Mak 2013;13(Suppl 2):S14. https://doi.org/10.1186/1472-6947-13-S2-S14.
48. Sepucha KR, Simmons LH, Barry MJ, Edgman-Levitan S, Licurse AM, Chaguturu SK. Ten years, forty decision aids, and thousands of patient uses: shared decision making at Massachusetts General Hospital. Health Aff (Millwood) 2016;35:630–6. https://doi.org/10.1377/hlthaff.2015.1376.
49. Montgomery AA, Harding J, Fahey T. Shared decision making in hypertension: the impact of patient preferences on treatment choice. Fam Pract 2001;18:309–13.
50. Say RE, Thomson R. The importance of patient preferences in treatment decisions–challenges for doctors. BMJ 2003;327:542–5.
51. Braddock CH 3rd, Fihn SD, Levinson W, Jonsen AR, Pearlman RA. How doctors and patients discuss routine clinical decisions. Informed decision making in the outpatient setting. J Gen Intern Med 1997;12:339–45.
52. Braddock CH 3rd, Edwards KA, Hasenberg NM, Laidley TL, Levinson W. Informed decision making in outpatient practice: time to get back to basics. JAMA 1999;282:2313–20.
53. Glasziou P, Burls A, Gilbert R. Evidence based medicine and the medical curriculum. BMJ 2008;337:a1253. https://doi.org/10.1136/bmj.a1253.
54. Hoffmann TC, Del Mar C. Clinicians’ expectations of the benefits and harms of treatments, screening, and tests: a systematic review. JAMA Intern Med 2017;177:407–19. https://doi.org/10.1001/jamainternmed.2016.8254.
55. Dizon JM, Grimmer-Somers K. Complex interventions required to comprehensively educate allied health practitioners on evidence-based practice. Adv Med Educ Pract 2011;2:8. https://doi.org/10.2147/AMEP.S19767.
56. Fischer F, Lange K, Klose K, Greiner W, Kraemer A Barriers and strategies in guideline implementation – a scoping review. Healthcare (Basel) 2016;4: pii: E36. https://doi.org/10.3390/healthcare4030036.
57. Greenhalgh T, Snow R, Ryan S, Rees S, Salisbury H. Six ‘biases’ against patients and carers in evidence-based medicine. BMC Med 2015;1:200. https://doi.org/10.1186/s12916-015-0437-x.
58. PLoS Medicine Editors. False hopes, unwarranted fears: the trouble with medical news stories. PLoS Med 2008;5:e118.
59. Shaughnessy AF, Gupta PS, Erlich DR, Slawson DC. Ability of an information mastery curriculum to improve residents’ skills and attitudes. Fam Med 2012;44:259–64.
60. Coomarasamy A, Khan KS. What is the evidence that postgraduate teaching in evidence based medicine changes anything? A systematic review. BMJ 2004;329:1017.