Type i interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation

Nature Immunology

Volumn 18, Issue 10, 2017, Pages 1104-1116

  Park, Sung Ho ^a   Kang, Kyuho ^a   Giannopoulou, Eugenia ^a,b   Qiao, Yu ^a   Kang, Keunsoo ^c   Kim, Geonho ^a   Park Min, Kyung Hyun ^a   Ivashkiv, Lionel B ^a,d  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b NEW YORK CITY COLLEGE OF TECHNOLOGY   (United States)

^c Dankook University   (South Korea)

^d Weill Cornell Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; TOLL LIKE RECEPTOR 4; TRANSPOSASE; TUMOR NECROSIS FACTOR; CYTOKINE; LIPOPOLYSACCHARIDE; PROTEIN BINDING; TRANSCRIPTION FACTOR;

ARTICLE; CELL REPROGRAMMING TECHNIQUE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CROSS TOLERANCE; EPIGENETICS; FEEDBACK SYSTEM; GENE INDUCTION; GENE TARGETING; HUMAN; INFLAMMATION; MACROPHAGE; NEXT GENERATION SEQUENCING; PRIORITY JOURNAL; RNA SEQUENCE; BINDING SITE; BIOLOGY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGY; METABOLISM; MONOCYTE; NUCLEOTIDE MOTIF; PROCEDURES; PROMOTER REGION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS;

BINDING SITES; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; CYTOKINES; EPIGENESIS, GENETIC; EPIGENOMICS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INFLAMMATION; INTERFERON TYPE I; LIPOPOLYSACCHARIDES; LUPUS ERYTHEMATOSUS, SYSTEMIC; MACROPHAGES; MONOCYTES; NUCLEOTIDE MOTIFS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85030615817     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3818     Document Type: Article

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