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Volumn 8, Issue 1, 2016, Pages 1-13

H3K4 tri-methylation breadth at transcription start sites impacts the transcriptome of systemic lupus erythematosus

Author keywords

Epigenome; H3K4me3; Integrative analysis; Pattern recognition; Systemic lupus erythematosus

Indexed keywords

HISTONE H3; TRANSCRIPTOME; HISTONE;

EID: 84956723148     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-016-0179-4     Document Type: Article
Times cited : (48)

References (39)
  • 2
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • COI: 1:CAS:528:DC%2BD2sXmtFKjsro%3D, PID: 17512414
    • Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, et al. High-resolution profiling of histone methylations in the human genome. Cell. 2007;129(4):823–37.
    • (2007) Cell , vol.129 , Issue.4 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.Y.4    Schones, D.E.5    Wang, Z.6
  • 3
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • COI: 1:CAS:528:DC%2BD2sXotlGmtrk%3D, PID: 17632057
    • Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell. 2007;130(1):77–88.
    • (2007) Cell , vol.130 , Issue.1 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 4
    • 84870058502 scopus 로고    scopus 로고
    • Facilitators and impediments of the pluripotency reprogramming factors’ initial engagement with the genome
    • COI: 1:CAS:528:DC%2BC38Xhs12gtbrL, PID: 23159369
    • Soufi A, Donahue G, Zaret KS. Facilitators and impediments of the pluripotency reprogramming factors’ initial engagement with the genome. Cell. 2012;151(5):994–1004. doi:10.1016/j.cell.2012.09.045.
    • (2012) Cell , vol.151 , Issue.5 , pp. 994-1004
    • Soufi, A.1    Donahue, G.2    Zaret, K.S.3
  • 5
    • 84905392053 scopus 로고    scopus 로고
    • H3K4me3 breadth is linked to cell identity and transcriptional consistency
    • COI: 1:CAS:528:DC%2BC2cXht1ymtLjP, PID: 25083876
    • Benayoun BA, Pollina EA, Ucar D, Mahmoudi S, Karra K, Wong ED, et al. H3K4me3 breadth is linked to cell identity and transcriptional consistency. Cell. 2014;158(3):673–88. doi:10.1016/j.cell.2014.06.027.
    • (2014) Cell , vol.158 , Issue.3 , pp. 673-688
    • Benayoun, B.A.1    Pollina, E.A.2    Ucar, D.3    Mahmoudi, S.4    Karra, K.5    Wong, E.D.6
  • 6
    • 77955172885 scopus 로고    scopus 로고
    • Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors
    • COI: 1:CAS:528:DC%2BC3cXos1ait7Y%3D, PID: 20622861
    • Adli M, Zhu J, Bernstein BE. Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors. Nat Methods. 2010;7(8):615–8. doi:10.1038/nmeth.1478.
    • (2010) Nat Methods , vol.7 , Issue.8 , pp. 615-618
    • Adli, M.1    Zhu, J.2    Bernstein, B.E.3
  • 7
    • 77956639427 scopus 로고    scopus 로고
    • Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network
    • COI: 1:CAS:528:DC%2BC3cXnslChsb4%3D, PID: 20569696
    • Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, et al. Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. Cell Stem Cell. 2010;6(6):591–602. doi:10.1016/j.stem.2010.03.016.
    • (2010) Cell Stem Cell , vol.6 , Issue.6 , pp. 591-602
    • Aiden, A.P.1    Rivera, M.N.2    Rheinbay, E.3    Ku, M.4    Coffman, E.J.5    Truong, T.T.6
  • 8
    • 79952638264 scopus 로고    scopus 로고
    • Cellular decision making and biological noise: from microbes to mammals
    • COI: 1:CAS:528:DC%2BC3MXjsFCrtr4%3D, PID: 21414483
    • Balazsi G, van Oudenaarden A, Collins JJ. Cellular decision making and biological noise: from microbes to mammals. Cell. 2011;144(6):910–25. doi:10.1016/j.cell.2011.01.030.
    • (2011) Cell , vol.144 , Issue.6 , pp. 910-925
    • Balazsi, G.1    van Oudenaarden, A.2    Collins, J.J.3
  • 9
    • 40049093765 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BD1cXisF2mtbo%3D, PID: 18305268
    • Rahman A, Isenberg DA. Systemic lupus erythematosus. N Engl J Med. 2008;358(9):929–39.
    • (2008) N Engl J Med , vol.358 , Issue.9 , pp. 929-939
    • Rahman, A.1    Isenberg, D.A.2
  • 10
    • 84925303912 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 and histone H4 acetylation in systemic lupus erythematosus
    • PID: 25611806
    • Leung YT, Shi L, Maurer K, Song L, Zhang Z, Petri M, et al. Interferon regulatory factor 1 and histone H4 acetylation in systemic lupus erythematosus. Epigenetics. 2015;10(3):191–9. doi:10.1080/15592294.2015.1009764.
    • (2015) Epigenetics , vol.10 , Issue.3 , pp. 191-199
    • Leung, Y.T.1    Shi, L.2    Maurer, K.3    Song, L.4    Zhang, Z.5    Petri, M.6
  • 11
    • 84900415568 scopus 로고    scopus 로고
    • The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs
    • PID: 24796678
    • Shi L, Zhang Z, Yu AM, Wang W, Wei Z, Akhter E, et al. The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs. PLoS One. 2014;9(5):e93846. doi:10.1371/journal.pone.0093846.
    • (2014) PLoS One , vol.9 , Issue.5 , pp. 93846
    • Shi, L.1    Zhang, Z.2    Yu, A.M.3    Wang, W.4    Wei, Z.5    Akhter, E.6
  • 13
    • 84956829686 scopus 로고    scopus 로고
    • Zhang Z, Shi L, Song L, Ephrem E, Petri M, Sullivan K. IRF1 marks activated genes in SLE and can induce target gene expression. Arthritis and Rheumatism. 2015;in press
    • Zhang Z, Shi L, Song L, Ephrem E, Petri M, Sullivan K. IRF1 marks activated genes in SLE and can induce target gene expression. Arthritis and Rheumatism. 2015;in press.
  • 14
    • 0344492212 scopus 로고    scopus 로고
    • Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
    • COI: 1:CAS:528:DC%2BD3sXitVaisb8%3D, PID: 12604793
    • Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Ortmann WA, Espe KJ, et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci U S A. 2003;100(5):2610–5.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.5 , pp. 2610-2615
    • Baechler, E.C.1    Batliwalla, F.M.2    Karypis, G.3    Gaffney, P.M.4    Ortmann, W.A.5    Espe, K.J.6
  • 15
    • 0037451167 scopus 로고    scopus 로고
    • Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
    • COI: 1:CAS:528:DC%2BD3sXitlOgs74%3D, PID: 12642603
    • Bennett L, Palucka AK, Arce E, Cantrell V, Borvak J, Banchereau J, et al. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J Exp Med. 2003;197(6):711–23.
    • (2003) J Exp Med , vol.197 , Issue.6 , pp. 711-723
    • Bennett, L.1    Palucka, A.K.2    Arce, E.3    Cantrell, V.4    Borvak, J.5    Banchereau, J.6
  • 16
    • 10444248118 scopus 로고    scopus 로고
    • Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BD2MXls1egtA%3D%3D, PID: 15593221
    • Kirou KA, Lee C, George S, Louca K, Papagiannis IG, Peterson MG, et al. Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus. Arthritis Rheum. 2004;50(12):3958–67.
    • (2004) Arthritis Rheum , vol.50 , Issue.12 , pp. 3958-3967
    • Kirou, K.A.1    Lee, C.2    George, S.3    Louca, K.4    Papagiannis, I.G.5    Peterson, M.G.6
  • 17
    • 84947597215 scopus 로고    scopus 로고
    • Monocyte enhancers are highly altered in systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BC2MXhvVehsrfK, PID: 26442457
    • Shi L, Zhang Z, Song L, Leung YT, Petri MA, Sullivan KE. Monocyte enhancers are highly altered in systemic lupus erythematosus. Epigenomics. 2015;7(6):921–35. doi:10.2217/epi.15.47.
    • (2015) Epigenomics , vol.7 , Issue.6 , pp. 921-935
    • Shi, L.1    Zhang, Z.2    Song, L.3    Leung, Y.T.4    Petri, M.A.5    Sullivan, K.E.6
  • 18
    • 0742306875 scopus 로고    scopus 로고
    • GA-binding protein transcription factor: a review of GABP as an integrator of intracellular signaling and protein-protein interactions
    • COI: 1:CAS:528:DC%2BD2cXntVGqsw%3D%3D, PID: 14757430
    • Rosmarin AG, Resendes KK, Yang Z, McMillan JN, Fleming SL. GA-binding protein transcription factor: a review of GABP as an integrator of intracellular signaling and protein-protein interactions. Blood Cells Mol Dis. 2004;32(1):143–54.
    • (2004) Blood Cells Mol Dis , vol.32 , Issue.1 , pp. 143-154
    • Rosmarin, A.G.1    Resendes, K.K.2    Yang, Z.3    McMillan, J.N.4    Fleming, S.L.5
  • 19
    • 33847355216 scopus 로고    scopus 로고
    • The Ets transcription factor GABP is required for cell-cycle progression
    • PID: 17277770
    • Yang ZF, Mott S, Rosmarin AG. The Ets transcription factor GABP is required for cell-cycle progression. Nat Cell Biol. 2007;9(3):339–46. doi:10.1038/ncb1548.
    • (2007) Nat Cell Biol , vol.9 , Issue.3 , pp. 339-346
    • Yang, Z.F.1    Mott, S.2    Rosmarin, A.G.3
  • 20
    • 84907483941 scopus 로고    scopus 로고
    • Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
    • PID: 25258085
    • Saeed S, Quintin J, Kerstens HH, Rao NA, Aghajanirefah A, Matarese F, et al. Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity. Science. 2014;345(6204):1251086. doi:10.1126/science.1251086.
    • (2014) Science , vol.345 , Issue.6204 , pp. 1251086
    • Saeed, S.1    Quintin, J.2    Kerstens, H.H.3    Rao, N.A.4    Aghajanirefah, A.5    Matarese, F.6
  • 21
    • 84908602740 scopus 로고    scopus 로고
    • NF-kappaB directs dynamic super enhancer formation in inflammation and atherogenesis
    • COI: 1:CAS:528:DC%2BC2cXhs1agtrfM, PID: 25263595
    • Brown JD, Lin CY, Duan Q, Griffin G, Federation AJ, Paranal RM, et al. NF-kappaB directs dynamic super enhancer formation in inflammation and atherogenesis. Mol Cell. 2014;56(2):219–31. doi:10.1016/j.molcel.2014.08.024.
    • (2014) Mol Cell , vol.56 , Issue.2 , pp. 219-231
    • Brown, J.D.1    Lin, C.Y.2    Duan, Q.3    Griffin, G.4    Federation, A.J.5    Paranal, R.M.6
  • 22
    • 84870375316 scopus 로고    scopus 로고
    • Histone lysine methylation dynamics: establishment, regulation, and biological impact
    • COI: 1:CAS:528:DC%2BC38XhslKqtLvM, PID: 23200123
    • Black JC, Van Rechem C, Whetstine JR. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Mol Cell. 2012;48(4):491–507. doi:10.1016/j.molcel.2012.11.006.
    • (2012) Mol Cell , vol.48 , Issue.4 , pp. 491-507
    • Black, J.C.1    Van Rechem, C.2    Whetstine, J.R.3
  • 23
    • 79956367114 scopus 로고    scopus 로고
    • Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP
    • COI: 1:CAS:528:DC%2BC3MXmsVSktL8%3D, PID: 21518915
    • Crump NT, Hazzalin CA, Bowers EM, Alani RM, Cole PA, Mahadevan LC. Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. Proc Natl Acad Sci U S A. 2011;108(19):7814–9. doi:10.1073/pnas.1100099108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.19 , pp. 7814-7819
    • Crump, N.T.1    Hazzalin, C.A.2    Bowers, E.M.3    Alani, R.M.4    Cole, P.A.5    Mahadevan, L.C.6
  • 24
    • 0034068331 scopus 로고    scopus 로고
    • Monocytes from systemic lupus erythematous patients are severely altered in phenotype and lineage flexibility
    • COI: 1:STN:280:DC%2BD3c7pslymtw%3D%3D, PID: 10733475
    • Steinbach F, Henke F, Krause B, Thiele B, Burmester GR, Hiepe F. Monocytes from systemic lupus erythematous patients are severely altered in phenotype and lineage flexibility. Ann Rheum Dis. 2000;59(4):283–8.
    • (2000) Ann Rheum Dis , vol.59 , Issue.4 , pp. 283-288
    • Steinbach, F.1    Henke, F.2    Krause, B.3    Thiele, B.4    Burmester, G.R.5    Hiepe, F.6
  • 25
    • 33947186736 scopus 로고    scopus 로고
    • The TNFalpha locus is altered in monocytes from patients with systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BD2sXjtValtb8%3D, PID: 17276734
    • Sullivan KE, Suriano A, Dietzmann K, Lin J, Goldman D, Petri MA. The TNFalpha locus is altered in monocytes from patients with systemic lupus erythematosus. Clin Immunol. 2007;123(1):74–81.
    • (2007) Clin Immunol , vol.123 , Issue.1 , pp. 74-81
    • Sullivan, K.E.1    Suriano, A.2    Dietzmann, K.3    Lin, J.4    Goldman, D.5    Petri, M.A.6
  • 26
    • 31144439799 scopus 로고    scopus 로고
    • Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells
    • COI: 1:CAS:528:DC%2BD28XhsFeitLk%3D, PID: 16014673
    • Tas SW, Quartier P, Botto M, Fossati-Jimack L. Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells. Ann Rheum Dis. 2006;65(2):216–21.
    • (2006) Ann Rheum Dis , vol.65 , Issue.2 , pp. 216-221
    • Tas, S.W.1    Quartier, P.2    Botto, M.3    Fossati-Jimack, L.4
  • 27
    • 84896374738 scopus 로고    scopus 로고
    • A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers
    • COI: 1:CAS:528:DC%2BC2cXltVSqtro%3D, PID: 24656132
    • Cheng J, Blum R, Bowman C, Hu D, Shilatifard A, Shen S, et al. A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers. Mol Cell. 2014;53(6):979–92. doi:10.1016/j.molcel.2014.02.032.
    • (2014) Mol Cell , vol.53 , Issue.6 , pp. 979-992
    • Cheng, J.1    Blum, R.2    Bowman, C.3    Hu, D.4    Shilatifard, A.5    Shen, S.6
  • 28
    • 84894579192 scopus 로고    scopus 로고
    • Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release
    • COI: 1:CAS:528:DC%2BC3sXhvFyktrzO, PID: 24360279
    • Liu W, Ma Q, Wong K, Li W, Ohgi K, Zhang J, et al. Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release. Cell. 2013;155(7):1581–95. doi:10.1016/j.cell.2013.10.056.
    • (2013) Cell , vol.155 , Issue.7 , pp. 1581-1595
    • Liu, W.1    Ma, Q.2    Wong, K.3    Li, W.4    Ohgi, K.5    Zhang, J.6
  • 29
    • 34547126444 scopus 로고    scopus 로고
    • Regulation of transcript elongation through cooperative and ordered recruitment of cofactors
    • COI: 1:CAS:528:DC%2BD2sXns1ygu78%3D, PID: 17535807
    • Sharma M, George AA, Singh BN, Sahoo NC, Rao KV. Regulation of transcript elongation through cooperative and ordered recruitment of cofactors. J Biol Chem. 2007;282(29):20887–96. doi:10.1074/jbc.M701420200.
    • (2007) J Biol Chem , vol.282 , Issue.29 , pp. 20887-20896
    • Sharma, M.1    George, A.A.2    Singh, B.N.3    Sahoo, N.C.4    Rao, K.V.5
  • 30
    • 80455122751 scopus 로고    scopus 로고
    • Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation
    • COI: 1:CAS:528:DC%2BC3MXht12hsr3K, PID: 21983563
    • Zhao R, Nakamura T, Fu Y, Lazar Z, Spector DL. Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation. Nat Cell Biol. 2011;13(11):1295–304. doi:10.1038/ncb2341.
    • (2011) Nat Cell Biol , vol.13 , Issue.11 , pp. 1295-1304
    • Zhao, R.1    Nakamura, T.2    Fu, Y.3    Lazar, Z.4    Spector, D.L.5
  • 31
    • 79954562232 scopus 로고    scopus 로고
    • Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells
    • COI: 1:CAS:528:DC%2BC3MXkvFCrtbg%3D, PID: 21460038
    • Min IM, Waterfall JJ, Core LJ, Munroe RJ, Schimenti J, Lis JT. Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells. Genes Dev. 2011;25(7):742–54. doi:10.1101/gad.2005511.
    • (2011) Genes Dev , vol.25 , Issue.7 , pp. 742-754
    • Min, I.M.1    Waterfall, J.J.2    Core, L.J.3    Munroe, R.J.4    Schimenti, J.5    Lis, J.T.6
  • 32
    • 41349094797 scopus 로고    scopus 로고
    • Transcription regulation through promoter-proximal pausing of RNA polymerase II
    • COI: 1:CAS:528:DC%2BD1cXjs12ksLY%3D, PID: 18369138
    • Core LJ, Lis JT. Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science. 2008;319(5871):1791–2. doi:10.1126/science.1150843.
    • (2008) Science , vol.319 , Issue.5871 , pp. 1791-1792
    • Core, L.J.1    Lis, J.T.2
  • 33
    • 84923640030 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 marks activated genes and can induce target gene expression in systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BC2MXjtlSlsbo%3D, PID: 25418955
    • Zhang Z, Shi L, Song L, Ephrem E, Petri M, Sullivan KE. Interferon regulatory factor 1 marks activated genes and can induce target gene expression in systemic lupus erythematosus. Arthritis Rheumatol. 2015;67(3):785–96. doi:10.1002/art.38964.
    • (2015) Arthritis Rheumatol , vol.67 , Issue.3 , pp. 785-796
    • Zhang, Z.1    Shi, L.2    Song, L.3    Ephrem, E.4    Petri, M.5    Sullivan, K.E.6
  • 34
    • 84956782139 scopus 로고    scopus 로고
    • Shi L, Zhang Z, Song L, Leung Y, Petri M, Sullivan K. Monocyte enhancers are highly enriched in SLE. Epigenomics. 2015;in press
    • Shi L, Zhang Z, Song L, Leung Y, Petri M, Sullivan K. Monocyte enhancers are highly enriched in SLE. Epigenomics. 2015;in press.
  • 35
    • 45949109295 scopus 로고    scopus 로고
    • Polarization of primary human monocytes by IFN-gamma induces chromatin changes and recruits RNA Pol II to the TNF-alpha promoter
    • COI: 1:CAS:528:DC%2BD1cXkt1arsL0%3D, PID: 18390706
    • Garrett S, Dietzmann-Maurer K, Song L, Sullivan KE. Polarization of primary human monocytes by IFN-gamma induces chromatin changes and recruits RNA Pol II to the TNF-alpha promoter. J Immunol. 2008;180(8):5257–66.
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5257-5266
    • Garrett, S.1    Dietzmann-Maurer, K.2    Song, L.3    Sullivan, K.E.4
  • 36
    • 47549116348 scopus 로고    scopus 로고
    • LPS and poly I:C induce chromatin modifications at a novel upstream region of the IL-23 p19 promoter
    • COI: 1:CAS:528:DC%2BD1cXos1Wmt7Y%3D, PID: 18587636
    • Garrett S, Fitzgerald MC, Sullivan KE. LPS and poly I:C induce chromatin modifications at a novel upstream region of the IL-23 p19 promoter. Inflammation. 2008;31(4):235–46.
    • (2008) Inflammation , vol.31 , Issue.4 , pp. 235-246
    • Garrett, S.1    Fitzgerald, M.C.2    Sullivan, K.E.3
  • 37
    • 0038341918 scopus 로고    scopus 로고
    • Histone acetylation and chromatin conformation are regulated separately at the TNF alpha promoter in monocytes and macrophages
    • COI: 1:CAS:528:DC%2BD3sXksFegt70%3D, PID: 12773519
    • Lee JY, Kim NA, Sanford A, Sullivan KE. Histone acetylation and chromatin conformation are regulated separately at the TNF alpha promoter in monocytes and macrophages. J Leukoc Biol. 2003;73:862–71.
    • (2003) J Leukoc Biol , vol.73 , pp. 862-871
    • Lee, J.Y.1    Kim, N.A.2    Sanford, A.3    Sullivan, K.E.4
  • 39
    • 84859885816 scopus 로고    scopus 로고
    • Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
    • COI: 1:CAS:528:DC%2BC38Xjt1Cjsrc%3D, PID: 22383036
    • Trapnell C, Roberts A, Goff L, Pertea G, Kim D, Kelley DR, et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nat Protoc. 2012;7(3):562–78. doi:10.1038/nprot.2012.016.
    • (2012) Nat Protoc , vol.7 , Issue.3 , pp. 562-578
    • Trapnell, C.1    Roberts, A.2    Goff, L.3    Pertea, G.4    Kim, D.5    Kelley, D.R.6


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