The NF-κB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin tolerance

Journal of Biological Chemistry

Volumn 284, Issue 41, 2009, Pages 27857-27865

  Chen, Xiaoping ^a,b   El Gazzar, Mohamed ^a   Yoza, Barbara K ^a   McCall, Charles E ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b National Institute for Communicable Disease Control and Prevention   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MODEL; CHROMATIN STRUCTURE; CO-IMMUNOPRECIPITATIONS; DNA MODIFICATION; EPIGENETIC SILENCING; GENE TRANSCRIPTIONS; GLUTATHIONE-S-TRANSFERASE; HETEROCHROMATIN FORMATION; HISTONE H3; IN-VITRO; IN-VIVO; INTERLEUKIN-1; LYSINE-9; METHYLTRANSFERASES; PROINFLAMMATORY; REL HOMOLOGY DOMAINS; SALIENT FEATURES; SYSTEMIC INFLAMMATION; TRANSCRIPTIONAL SILENCING;

AMINO ACIDS; CELL MEMBRANES; ENZYMES; GENES; NUCLEIC ACIDS; PLANTS (BOTANY); TRANSCRIPTION FACTORS;

TRANSCRIPTION;

ENDOTOXIN; GLUTATHIONE TRANSFERASE; HETEROCHROMATIN PROTEIN 1; HISTONE H3 LYSINE METHYLTRANSFERASE G9A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; METHYLTRANSFERASE; TRANSCRIPTION FACTOR REL; TRANSCRIPTION FACTOR RELB; UNCLASSIFIED DRUG; EHMT2 PROTEIN, HUMAN; HISTOCOMPATIBILITY ANTIGEN; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 4;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; HETEROCHROMATIN; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; STRUCTURAL HOMOLOGY; CELL LINE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INFLAMMATION; METABOLISM; RNA INTERFERENCE; T LYMPHOCYTE;

CELL LINE; ENDOTOXINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; GENE SILENCING; HISTOCOMPATIBILITY ANTIGENS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; IMMUNE TOLERANCE; INFLAMMATION; INTERLEUKIN-1BETA; LYSINE; NF-KAPPA B; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELB;

EID: 70350463559     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.000950     Document Type: Article

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