Diabetes Enhances IL-17 Expression and Alters the Oral Microbiome to Increase Its Pathogenicity

Cell Host and Microbe

Volumn 22, Issue 1, 2017, Pages 120-128.e4

  Xiao, E ^a,b   Mattos, Marcelo ^b   Vieira, Gustavo Henrique Apolinário ^c   Chen, Shanshan ^b,d   Corrêa, Jôice Dias ^e   Wu, Yingying ^b,d   Albiero, Mayra Laino ^f   Bittinger, Kyle ^g   Graves, Dana T ^b  

^a PEKING UNIVERSITY SCHOOL AND HOSPITAL OF STOMATOLOGY   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d SICHUAN UNIVERSITY   (China)

^e FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^f UNIVERSITY OF CAMPINAS   (Brazil)

^g CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

bone loss; diabetes; dysbiosis; IL 17; microbiota; osteoclast; pathogen; periodontitis

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; BACTERIAL DNA; RNA 16S; TNFSF11 PROTEIN, MOUSE;

AEROCOCCUS; ANIMAL EXPERIMENT; ARTICLE; BACILLALES; BACTERIAL VIRULENCE; CLOSTRIDIALES; CLOSTRIDIUM; CONTROLLED STUDY; CORYNEBACTERIUM; DIABETES MELLITUS; ENTEROBACTERIACEAE; ENTEROCOCCUS; FEMALE; GERMFREE MOUSE; LACTOBACILLUS; MOUSE; MOUTH FLORA; NEUTROPHIL; NONHUMAN; OSTEOLYSIS; PERIODONTAL DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPOROSARCINA; STAPHYLOCOCCUS; ALVEOLAR BONE LOSS; ANIMAL; BACTERIAL COUNT; BACTERIAL GENE; BACTERIUM; C57BL MOUSE; COMPLICATION; DIAGNOSTIC IMAGING; EXPERIMENTAL DIABETES MELLITUS; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; MICROBIOLOGY; MICROFLORA; MOUTH; NEUTROPHIL CHEMOTAXIS; OSTEOCLAST; PATHOGENICITY; PATHOLOGY; PERIODONTITIS; SEQUENCE ANALYSIS; VIRULENCE;

ALVEOLAR BONE LOSS; ANIMALS; BACTERIA; BONE RESORPTION; COLONY COUNT, MICROBIAL; DIABETES MELLITUS, EXPERIMENTAL; DNA, BACTERIAL; GENES, BACTERIAL; INFLAMMATION; INTERLEUKIN-17; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MICROBIOTA; MOUTH; NEUTROPHIL INFILTRATION; OSTEOCLASTS; PERIODONTITIS; RANK LIGAND; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS; TOOTH LOSS; VIRULENCE;

EID: 85030469022     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.06.014     Document Type: Article

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