Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity

Cell Host and Microbe

Volumn 21, Issue 1, 2017, Pages 23-34

  Peng, Wenjie ^a   de Vries, Robert P ^a,c   Grant, Oliver C ^b   Thompson, Andrew J ^a   McBride, Ryan ^a   Tsogtbaatar, Buyankhishig ^a   Lee, Peter S ^a,d   Razi, Nahid ^a   Wilson, Ian A ^a   Woods, Robert J ^b   Paulson, James C ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

airway; bidentate binding; chemo enzymatic synthesis; extended branched glycans; H3N2; hemagglutinin; influenza virus; poly N acetyl lactosamine; receptor specificity; sialoside microarray

Indexed keywords

GLYCAN; HEMAGGLUTININ; LACTOSE; LIPID; POLY N ACETYL LACTOSAMINE; RECEPTOR; SIALIDASE; UNCLASSIFIED DRUG; GALACTAN; INFLUENZA VIRUS HEMAGGLUTININ; N ACETYLNEURAMINIC ACID; POLY-N-ACETYLGALACTOSAMINE; POLYSACCHARIDE; VIRUS RECEPTOR;

ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; INFECTION; INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H3N2); MDCK CELL LINE; PRIORITY JOURNAL; ANIMAL; CELL LINE; DOG; GENETICS; HEK293 CELL LINE; INFLUENZA A VIRUS (H3N8); INFLUENZA A VIRUS (H5N1); METABOLISM; MOLECULAR DYNAMICS; SPECIES DIFFERENCE; VIRUS ATTACHMENT;

ANIMALS; CELL LINE; DOGS; GALACTANS; HEK293 CELLS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA A VIRUS, H3N8 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; MADIN DARBY CANINE KIDNEY CELLS; MOLECULAR DYNAMICS SIMULATION; N-ACETYLNEURAMINIC ACID; POLYSACCHARIDES; RECEPTORS, VIRUS; SPECIES SPECIFICITY; VIRUS ATTACHMENT;

EID: 85009935441     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2016.11.004     Document Type: Article

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