Phyllanthus emblica L. (Indian gooseberry) extracts protect against retinal degeneration in a mouse model of amyloid beta-induced Alzheimer's disease

Journal of Functional Foods

Volumn 37, Issue , 2017, Pages 330-338

  Jang, Holim ^a,b   Srichayet, Phisamai ^c   Park, Woo Jung ^d   Heo, Ho Jin ^e   Kim, Dae Ok ^f   Tongchitpakdee, Sasitorn ^c   Kim, Tae Jin ^g   Jung, Sang Hoon ^b   Lee, Chang Yong ^a  

^a Cornell University ^*  (United States)

^b Korea Institute of Science and Technology   (South Korea)

^c KASETSART UNIVERSITY   (Thailand)

^d Gangneung Wonju National University   (South Korea)

^e Gyeongsang National University   (South Korea)

^f Kyung Hee University   (South Korea)

^g Pusan National University   (South Korea)

Author keywords

Alzheimer's disease; Amyloid beta; Indian gooseberry; Retinal degeneration

Indexed keywords

EID: 85029912974     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2017.07.056     Document Type: Article

References (54)

1. Afshari, A.R., Sadeghnia, H.R., Mollazadeh, H., A review on potential mechanisms of Terminalia chebula in Alzheimer's disease. Advances in Pharmacological Sciences, 2016, 2016, 8964849.
2. Barthakur, N.N., Arnold, N.P., Chemical analysis of the emblic (Phyllanthus emblica L.) and its potential as a food source. Scientia Horticulturae 47 (1991), 99–105.
3. Berisha, F., Feke, G.T., Trempe, C.L., McMeel, J.W., Schepens, C.L., Retinal abnormalities in early Alzheimer's disease. Investigative Ophthalmology & Visual Science 48 (2007), 2285–2289.
4. Birch, D.G., Wen, Y., Locke, K., Hood, D.C., Rod sensitivity, cone sensitivity, and photoreceptor layer thickness in retinal degenerative diseases. Investigative Ophthalmology & Visual Science 52 (2011), 7141–7147.
5. Cao, L., Liu, C., Wang, F., Wang, H., SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-kappa B pathway. Brazilian Journal of Medical and Biological Research 46 (2013), 659–669.
6. Chang, K.-C., Laffin, B., Ponder, J., Énzsöly, A., Németh, J., LaBarbera, D.V., Petrash, J.M., Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues. Chemico-Biological Interactions 202 (2013), 283–287.
7. Chidlow, G., Osborne, N.N., Rat retinal ganglion cell loss caused by kainate, NMDA and ischemia correlates with a reduction in mRNA and protein of Thy-1 and neurofilament light. Brain Research 963 (2003), 298–306.
8. Chiu, K., Chan, T.F., Wu, A., Leung, I.Y.P., So, K.F., Chang, R.C.C., Neurodegeneration of the retina in mouse models of Alzheimer's disease: What can we learn from the retina?. Age 34 (2012), 633–649.
9. Curcio, C.A., Drucker, D.N., Retinal ganglion cells in Alzheimer's disease and aging. Annals of Neurology 33 (1993), 248–257.
10. Dhitavat, S., Ortiz, D., Rogers, E., Rivera, E., Shea, T.B., Folate, vitamin E, and acetyl-L-carnitine provide synergistic protection against oxidative stress resulting from exposure of human neuroblastoma cells to amyloid-beta. Brain Research 1061 (2005), 114–117.
11. Donmez, G., Guarente, L., Aging and disease: Connections to sirtuins. Aging Cell 9 (2010), 285–290.
12. Dutescu, R.M., Li, Q.-X., Crowston, J., Masters, C., Baird, P., Culvenor, J., Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease. Graefe's Archive for Clinical and Experimental Ophthalmology 247 (2009), 1213–1221.
13. Guo, L., Duggan, J., Cordeiro, M., Alzheimer's disease and retinal neurodegeneration. Current Alzheimer Research 7 (2010), 3–14.
14. Guo, L., Duggan, J., Cordeiro, M.F., Alzheimer's disease and retinal neurodegeneration. Current Alzheimer Research 7 (2010), 3–14.
15. Jain, S., Khurdiya, D.S., Vitamin C enrichment of fruit juice based ready-to-serve beverages through blending of Indian gooseberry (Emblica officinalis Gaertn.) juice. Plant Foods for Human Nutrition 59 (2004), 63–66.
16. Jang, H., Ahn, H.R., Jo, H., Kim, K.-A., Lee, E.H., Lee, K.W., Lee, C., Chlorogenic acid and coffee prevent hypoxia-induced retinal degeneration. Journal of Agricultural and Food Chemistry 62 (2013), 182–191.
17. Jo, H., Choi, S.J., Jung, S.H., Protective effects of a compound isolated from Alnus japonica on oxidative stress-induced death in transformed retinal ganglion cells. Food and Chemical Toxicology 56 (2013), 425–435.
18. Jung Choi, S., Kim, M.J., Jin Heo, H., Kim, J.K., Jin Jun, W., Kim, H.K., Shin, D.H., Ameliorative effect of 1,2-benzenedicarboxylic acid dinonyl ester against amyloid beta peptide-induced neurotoxicity. Amyloid 16 (2009), 15–24.
19. Jung, S.H., Kim, B.J., Lee, E.H., Osborne, N.N., Isoquercitrin is the most effective antioxidant in the plant Thuja orientalis and able to counteract oxidative-induced damage to a transformed cell line (RGC-5 cells). Neurochemistry International 57 (2010), 713–721.
20. Kadowaki, H., Nishitoh, H., Urano, F., Sadamitsu, C., Matsuzawa, A., Takeda, K., Nagano, T., Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation. Cell Death & Differentiation 12 (2005), 19–24.
21. Kalt, W., Hanneken, A., Milbury, P., Tremblay, F., Recent research on polyphenolics in vision and eye health. Journal of Agricultural and Food Chemistry 58 (2010), 4001–4007.
22. Kim, K.-A., Kang, K.D., Lee, E.H., Nho, C.W., Jung, S.H., Edible wild vegetable, Gymnaster koraiensis protects retinal ganglion cells against oxidative stress. Food and Chemical Toxicology 49 (2011), 2131–2143.
23. Kirbas, S., Turkyilmaz, K., Anlar, O., Tufekci, A., Durmus, M., Retinal nerve fiber layer thickness in patients with Alzheimer disease. Journal of Neuro-ophthalmology 33 (2013), 58–61.
24. Kumar, K.S., Bhowmik, D., Dutta, A., Yadav, A.P., Paswan, S., Srivastava, S., Deb, L., Recent trends in potential traditional Indian herbs Emblica officinalis and its medicinal importance. Journal of Pharmacognosy and Phytochemistry 1 (2012), 18–28.
25. Kumaran, A., Karunakaran, R.J., Nitric oxide radical scavenging active components from Phyllanthus emblica L. Plant Foods for Human Nutrition 61 (2006), 1–5.
26. LeBel, C.P., Ischiropoulos, H., Bondy, S.C., Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chemical Research in Toxicology 5 (1992), 227–231.
27. Lindsey, J.D., Duong-Polk, K.X., Dai, Y., Nguyen, D.H., Leung, C.K., Weinreb, R.N., Protection by an oral disubstituted hydroxylamine derivative against loss of retinal ganglion cell differentiation following optic nerve crush. PLoS ONE, 8, 2013, e65966.
28. Liu, X., Zhao, M., Wang, J., Yang, B., Jiang, Y., Antioxidant activity of methanolic extract of emblica fruit (Phyllanthus emblica L.) from six regions in China. Journal of Food Composition and Analysis 21 (2008), 219–228.
29. Lu, Y., Li, Z., Zhang, X., Ming, B., Jia, J., Wang, R., Ma, D., Retinal nerve fiber layer structure abnormalities in early Alzheimer's disease: Evidence in optical coherence tomography. Neuroscience Letters 480 (2010), 69–72.
30. Mayachiew, P., Devahastin, S., Antimicrobial and antioxidant activities of Indian gooseberry and galangal extracts. LWT-Food Science and Technology 41 (2008), 1153–1159.
31. Mayachiew, P., Devahastin, S., Antimicrobial and antioxidant activities of Indian gooseberry and galangal extracts. LWT – Food Science and Technology 41 (2008), 1153–1159.
32. Mendez, M.F., Mendez, M., Martin, R., Smyth, K.A., Whitehouse, P., Complex visual disturbances in Alzheimer's disease. Neurology, 40, 1990 439-439.
33. Miller, M.G., Shukitt-Hale, B., Berry fruit enhances beneficial signaling in the brain. Journal of Agricultural and Food Chemistry 60 (2012), 5709–5715.
34. Poltanov, E.A., Shikov, A.N., Dorman, H.J.D., Pozharitskaya, O.N., Makarov, V.G., Tikhonov, V.P., Hiltunen, R., Chemical and antioxidant evaluation of Indian gooseberry (Emblica officinalis gaertn., syn. Phyllanthus emblica L.) supplements. Phytotherapy Research 23 (2009), 1309–1315.
35. Porcu, M., Chiarugi, A., The emerging therapeutic potential of sirtuin-interacting drugs: From cell death to lifespan extension. Trends in Pharmacological Sciences 26 (2005), 94–103.
36. Price, N.L., Gomes, A.P., Ling, A.J.Y., Duarte, F.V., Martin-Montalvo, A., North, B.J., Sinclair, D.A., SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metabolism 15 (2012), 675–690.
37. Rizzo, M., Anderson, S., Dawson, J., Myers, R., Ball, K., Visual attention impairments in Alzheimer's disease. Neurology 54 (2000), 1954–1959.
38. Rizzo, M., Anderson, S.W., Dawson, J., Nawrot, M., Vision and cognition in Alzheimer's disease. Neuropsychologia 38 (2000), 1157–1169.
39. Roher, A.E., Lowenson, J.D., Clarke, S., Woods, A.S., Cotter, R.J., Gowing, E., Ball, M.J., beta-Amyloid-(1–42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer disease. Proceedings of the National Academy of Sciences 90 (1993), 10836–10840.
40. Sadun, A.A., Bassi, C.J., Optic nerve damage in Alzheimer's disease. Ophthalmology 97 (1990), 9–17.
41. Son, J.-E., Lee, B.H., Nam, T.G., Im, S., Chung, D.K., Lee, J.M., Kim, D.-O., Flavonols from the ripe fruits of Opuntia ficus-indica var. saboten protect neuronal PC-12 cells against oxidative stress. Journal of Food Biochemistry 38 (2014), 518–526.
42. Srivasuki, K. (2012). Nutritional and health care benefits of Amla. Journal of Pharmacognosy, 3.
43. Van Bergen, N.J., Wood, J.P., Chidlow, G., Trounce, I.A., Casson, R.J., Ju, W.-K., Crowston, J.G., Recharacterization of the RGC-5 retinal ganglion cell line. Investigative Ophthalmology & Visual Science 50 (2009), 4267–4272.
44. Wang, Y., Huo, Y.Z., Zhao, L., Lu, F., Wang, O., Yang, X., Zhou, F., Cyanidin-3-glucoside and its phenolic acid metabolites attenuate visible light-induced retinal degeneration in vivo via activation of Nrf2/HO-1 pathway and NF-B suppression. Molecular Nutrition & Food Research 60 (2016), 1564–1577.
45. Wang, Y., Kim, H.J., Sparrow, J.R., Quercetin and cyanidin-3-glucoside protect against photooxidation and photodegradation of A2E in retinal pigment epithelial cells. Experimental Eye Research 160 (2017), 45–55.
46. Wang, Y., Zhang, D., Liu, Y., Wang, D., Liu, J., Ji, B., The protective effects of berry-derived anthocyanins against visible light-induced damage in human retinal pigment epithelial cells. Journal of the Science of Food and Agriculture 95 (2015), 936–944.
47. Wang, Y., Zhao, L., Lu, F., Yang, X., Deng, Q., Ji, B., Huang, F., Retinoprotective effects of bilberry anthocyanins via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms in a visible light-induced retinal degeneration model in pigmented rabbits. Molecules 20 (2015), 22395–22410.
48. Wyss-Coray, T., Inflammation in Alzheimer disease: Driving force, bystander or beneficial response? [10.1038/nm1484]. Nature Medicine 12 (2006), 1005–1015.
49. Yang, B., Kortesniemi, M., Liu, P., Karonen, M., Salminen, J.P., Analysis of hydrolyzable tannins and other phenolic compounds in emblic leafflower (Phyllanthus emblica L.) fruits by high performance liquid chromatography-electrospray ionization mass spectrometry. Journal of Agriculture and Food Chemistry 60 (2012), 8672–8683.
50. Yang, C.S., Tzou, B.C., Liu, Y.P., Tsai, M.J., Shyue, S.K., Tzeng, S.F., Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by the addition of antioxidants and the reduction of intracellular calcium. Journal of Cellular Biochemistry 103 (2008), 825–834.
51. Yao, Z.-X., Drieu, K., Papadopoulos, V., The Ginkgo biloba extract EGb 761 rescues the PC12 neuronal cells from β-amyloid-induced cell death by inhibiting the formation of β-amyloid-derived diffusible neurotoxic ligands. Brain Research 889 (2001), 181–190.
52. Yatin, S.M., Varadarajan, S., Butterfield, D.A., Vitamin E prevents Alzheimer's amyloid ß-Peptide (1–42)-induced neuronal protein oxidation and reactive oxygen species production. Journal of Alzheimer's Disease 2 (2000), 123–131.
53. Zhang, B., Safa, R., Rusciano, D., Osborne, N.N., Epigallocatechin gallate, an active ingredient from green tea, attenuates damaging influences to the retina caused by ischemia/reperfusion. Brain Research 1159 (2007), 40–53.
54. Zuo, L., Khan, R.S., Lee, V., Dine, K., Wu, W., Shindler, K.S., SIRT1 promotes RGC survival and delays loss of function following optic nerve crush. Investigative Ophthalmology & Visual Science 54 (2013), 5097–5102.