Tumor Acidic Microenvironment Targeted Drug Delivery Based on pHLIP-Modified Mesoporous Organosilica Nanoparticles

ACS Applied Materials and Interfaces

Volumn 9, Issue 36, 2017, Pages 30543-30552

  Zhang, Yunlei ^a   Dang, Meng ^d   Tian, Ying ^a   Zhu, Yefei ^c   Liu, Wenfei ^a   Tian, Wei ^a   Su, Yunyan ^a   Ni, Qianqian ^a   Xu, Chaoli ^b   Lu, Nan ^a   Tao, Jun ^d   Li, Yanjun ^a   Zhao, Shuang ^a   Zhao, Ying ^a   Yang, Zhenlu ^a   Sun, Li ^c   Teng, Zhaogang ^a   Lu, Guangming ^a,b  

^a JINLING HOSPITAL   (China)

^b NANJING UNIVERSITY   (China)

^c THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^d NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

breast cancer; drug delivery; mesoporous organosilica nanoparticles; tumor acidic microenvironment; tumor targeting

Indexed keywords

BIOCOMPATIBILITY; CELLS; CHEMOTHERAPY; CYTOLOGY; CYTOTOXICITY; DISEASES; DRUG DELIVERY; DRUG INTERACTIONS; ENZYME ACTIVITY; MESOPOROUS MATERIALS; NANOPARTICLES; PEPTIDES; PH EFFECTS; SILICA; TUMORS;

ACIDIC MICROENVIRONMENT; BREAST CANCER; CHEMOTHERAPEUTIC DRUGS; DRUG DELIVERY SYSTEM; MESOPOROUS ORGANOSILICAS; THERAPEUTIC EFFICACY; TUMOR MICROENVIRONMENT; TUMOR TARGETING;

TARGETED DRUG DELIVERY;

DOXORUBICIN; NANOPARTICLE;

BREAST TUMOR; DRUG DELIVERY SYSTEM; HUMAN; MCF-7 CELL LINE; PH; TUMOR MICROENVIRONMENT;

BREAST NEOPLASMS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGEN-ION CONCENTRATION; MCF-7 CELLS; NANOPARTICLES; TUMOR MICROENVIRONMENT;

EID: 85029509813     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.7b10840     Document Type: Article

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