A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Ruiz, Victoria E ^a   Battaglia, Thomas ^a   Kurtz, Zachary D ^a   Bijnens, Luc ^b   Ou, Amy ^a   Engstrand, Isak ^c   Zheng, Xuhui ^a   Iizumi, Tadasu ^a   Mullins, Briana J ^a   Müller, Christian L ^d   Cadwell, Ken ^a   Bonneau, Richard ^d,e,f   Perez Perez, Guillermo I ^a   Blaser, Martin J ^a,g  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^c KAROLINSKA INSTITUTE   (Sweden)

^d FLATIRON INSTITUTE   (United States)

^e NEW YORK UNIVERSITY   (United States)

^f NEW YORK UNIVERSITY   (United States)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROLIDE; SECRETORY IMMUNOGLOBULIN; TYLOSIN TARTRATE; ANTIINFECTIVE AGENT; IMMUNOGLOBULIN A; TYLOSIN;

ANTIBIOTICS; DIGESTIVE SYSTEM; GENE EXPRESSION; IMMUNITY; MICROBIAL ACTIVITY; MICROBIAL COMMUNITY; RODENT; TOPOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMMUNITY DYNAMICS; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; DRUG EXPOSURE; FEMALE; GENE EXPRESSION; ILEUM; IMMUNE SYSTEM; IMMUNITY; IMMUNOMODULATION; INTESTINE FLORA; LONG TERM EXPOSURE; LYMPHOCYTE SUBPOPULATION; MALE; MICROBIAL COMMUNITY; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; T LYMPHOCYTE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; NEWBORN;

MURINAE;

ANIMALS; ANIMALS, NEWBORN; ANTI-BACTERIAL AGENTS; FEMALE; GASTROINTESTINAL MICROBIOME; GENE EXPRESSION REGULATION; ILEUM; IMMUNE SYSTEM; IMMUNOGLOBULIN A; MALE; MICE, INBRED C57BL; TYLOSIN;

EID: 85029363669     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00531-6     Document Type: Article

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