Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet

Genome Medicine

Volumn 8, Issue 1, 2016, Pages

  Mahana, Douglas ^a   Trent, Chad M ^b   Kurtz, Zachary D ^a   Bokulich, Nicholas A ^b   Battaglia, Thomas ^b   Chung, Jennifer ^b   Müller, Christian L ^c,d   Li, Huilin ^b   Bonneau, Richard A ^a,c,d   Blaser, Martin J ^a,b,e  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEW YORK UNIVERSITY   (United States)

^d Simons Center for Data Analysis   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GHRELIN; INTERLEUKIN 6; LEPTIN; PENICILLIN G; ANTIINFECTIVE AGENT; AUTACOID; CYTOKINE; GLUCOSE; HORMONE; INSULIN; RNA 16S;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BODY COMPOSITION; BODY WEIGHT; CONTROLLED STUDY; DRUG EXPOSURE; ENERGY BALANCE; FAT MASS; FECES ANALYSIS; FEMALE; FOOD INTAKE; GROWTH RATE; HOMEOSTASIS; INSULIN RESISTANCE; INTESTINE FLORA; LIPID DIET; LIVER DISEASE; MALE; MICROBIAL COMMUNITY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; ADVERSE EFFECTS; ANIMAL; BIODIVERSITY; BLOOD; DISEASE MODEL; DRUG EFFECTS; ENERGY METABOLISM; GENETICS; LIPID METABOLISM; LIVER DISEASES; METABOLISM; METAGENOME; METAGENOMICS; MICROBIOLOGY; NON-ALCOHOLIC FATTY LIVER DISEASE; PHYLOGENY; TIME FACTOR;

ADIPOSITY; ANIMALS; ANTI-BACTERIAL AGENTS; BIODIVERSITY; BODY COMPOSITION; BODY WEIGHT; CYTOKINES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GASTROINTESTINAL MICROBIOME; GLUCOSE; HOMEOSTASIS; HORMONES; INFLAMMATION MEDIATORS; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; LIVER DISEASES; METAGENOME; METAGENOMICS; MICE; NON-ALCOHOLIC FATTY LIVER DISEASE; PHENOTYPE; PHYLOGENY; RNA, RIBOSOMAL, 16S; TIME FACTORS;

EID: 84964240579     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-016-0297-9     Document Type: Article

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