cGAS Conducts Micronuclei DNA Surveillance

Trends in Cell Biology

Volumn 27, Issue 10, 2017, Pages 697-698

  de Oliveira Mann, Carina C ^a,b   Kranzusch, Philip J ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

cGAS; DNA damage; innate immune signaling; micronuclei; STING

Indexed keywords

ADAPTOR PROTEIN; CASPASE; CHEMOKINE; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP AMP SYNTHASE; CYTOKINE; DNA; DOUBLE STRANDED DNA; EXTRACHROMOSOMAL DNA; INTERFERON; PLASMID DNA; PROTEINASE; RIBONUCLEASE H; RIBONUCLEASE H2; STIMULATOR OF INTERFERON GENE; SYNTHETASE; UNCLASSIFIED DRUG; CYCLIC GUANOSINE MONOPHOSPHATE-ADENOSINE MONOPHOSPHATE; CYCLIC NUCLEOTIDE;

AICARDI GOUTIERES SYNDROME; AUTOIMMUNITY; CAMP SIGNALING; CANCER IMMUNOTHERAPY; CANCER RADIOTHERAPY; CARCINOGENESIS; CELL CYCLE PROGRESSION; CELL DEATH; CELL DIVISION; CELL GROWTH; CELL NUCLEUS MEMBRANE; CELL PROLIFERATION; CHROMATIN; CHROMOSOME; CHROMOTHRIPSIS; CYTOKINE RELEASE; DNA DAMAGE; DNA DETERMINATION; DNA REPAIR; ENZYME LOCALIZATION; GENOME; GENOMIC INSTABILITY; IMMUNE RESPONSE; IMMUNOSTIMULATION; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; MICRONUCLEUS; MICROSCOPY; MOLECULAR MECHANICS; MUTATION; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; RNA SEQUENCE; SHORT SURVEY; SIGNAL TRANSDUCTION; TUMOR IMMUNITY; ANIMAL; CELL CYCLE; CELL NUCLEUS; CYTOPLASM; GENETICS; HUMAN;

ANIMALS; CELL CYCLE; CELL NUCLEUS; CYTOPLASM; DNA; DNA DAMAGE; HUMANS; IMMUNITY, INNATE; INFLAMMATION; NUCLEOTIDES, CYCLIC; SIGNAL TRANSDUCTION;

EID: 85028699424     PISSN: 09628924     EISSN: 18793088     Source Type: Journal    
DOI: 10.1016/j.tcb.2017.08.007     Document Type: Short Survey

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