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Volumn 6, Issue 3, 2017, Pages

Control of immune cell entry through the tumour vasculature: A missing link in optimising melanoma immunotherapy?

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; B RAF KINASE INHIBITOR; CELL ADHESION MOLECULE; CHEMOKINE;

EID: 85028529620     PISSN: None     EISSN: 20500068     Source Type: Journal    
DOI: 10.1038/cti.2017.7     Document Type: Review
Times cited : (24)

References (100)
  • 1
    • 84928770388 scopus 로고    scopus 로고
    • Neoantigens in cancer immunotherapy
    • Schumacher TN, Schreiber RD. Neoantigens in cancer immunotherapy. Science 2015; 348: 69-74.
    • (2015) Science , vol.348 , pp. 69-74
    • Schumacher, T.N.1    Schreiber, R.D.2
  • 2
    • 84971231413 scopus 로고    scopus 로고
    • Resistance to combination BRAF and MEK inhibition in metastatic melanoma: Where to next?
    • Welsh SJ, Rizos H, Scolyer RA, Long GV. Resistance to combination BRAF and MEK inhibition in metastatic melanoma: Where to next? Eur J Cancer 2016; 62: 76-85.
    • (2016) Eur J Cancer , vol.62 , pp. 76-85
    • Welsh, S.J.1    Rizos, H.2    Scolyer, R.A.3    Long, G.V.4
  • 3
    • 84928062583 scopus 로고    scopus 로고
    • Immune checkpoint blockade: A common denominator approach to cancer therapy
    • Topalian Suzanne L, Drake Charles G, Pardoll Drew M. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 2015; 27: 450-461.
    • (2015) Cancer Cell , vol.27 , pp. 450-461
    • Topalian Suzanne, L.1    Drake Charles, G.2    Pardoll Drew, M.3
  • 5
    • 84990177918 scopus 로고    scopus 로고
    • Pembrolizumab (pembro) plus ipilimumab (ipi) for advanced melanoma: Results of the KEYNOTE-029 expansion cohort
    • (suppl; abstr 9506)
    • Long GV, Atkinson V, Cebon JS, Jameson MB, Fitzharris BM, McNeil CM et al. Pembrolizumab (pembro) plus ipilimumab (ipi) for advanced melanoma: results of the KEYNOTE-029 expansion cohort. J Clin Oncol 2016; 34: (suppl; abstr 9506).
    • (2016) J Clin Oncol , vol.34
    • Long, G.V.1    Atkinson, V.2    Cebon, J.S.3    Jameson, M.B.4    Fitzharris, B.M.5    McNeil, C.M.6
  • 6
    • 84928759208 scopus 로고    scopus 로고
    • Adoptive cell transfer as personalized immunotherapy for human cancer
    • Rosenberg SA, Restifo NP. Adoptive cell transfer as personalized immunotherapy for human cancer. Science 2015; 348: 62-68.
    • (2015) Science , vol.348 , pp. 62-68
    • Rosenberg, S.A.1    Restifo, N.P.2
  • 7
    • 79960299888 scopus 로고    scopus 로고
    • Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
    • Rosenberg SA, Yang JC, Sherry RM, Kammula US, Hughes MS, Phan GQ et al. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 2011; 17: 4550-4557.
    • (2011) Clin Cancer Res , vol.17 , pp. 4550-4557
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3    Kammula, U.S.4    Hughes, M.S.5    Phan, G.Q.6
  • 8
    • 84964317521 scopus 로고    scopus 로고
    • GD2-specific CAR T cells undergo potent activation and deletion following antigen encounter but can be protected from activation-induced cell death by PD-1 blockade
    • Gargett T, Yu W, Dotti G, Yvon ES, Christo SN, Hayball JD et al. GD2-specific CAR T cells undergo potent activation and deletion following antigen encounter but can be protected from activation-induced cell death by PD-1 blockade. Mol Ther 2016; 24: 1135-1149.
    • (2016) Mol Ther , vol.24 , pp. 1135-1149
    • Gargett, T.1    Yu, W.2    Dotti, G.3    Yvon, E.S.4    Christo, S.N.5    Hayball, J.D.6
  • 10
    • 0842268394 scopus 로고    scopus 로고
    • T-cell activation marker expression on tumor-infiltrating lymphocytes as prognostic factor in cutaneous malignant melanoma
    • Ladányi A, Somlai B, Gilde K, Fejös Z, Gaudi I, Tímár J. T-cell activation marker expression on tumor-infiltrating lymphocytes as prognostic factor in cutaneous malignant melanoma. Clin Cancer Res 2004; 10: 521-530.
    • (2004) Clin Cancer Res , vol.10 , pp. 521-530
    • Ladányi, A.1    Somlai, B.2    Gilde, K.3    Fejös, Z.4    Gaudi, I.5    Tímár, J.6
  • 11
    • 24644488201 scopus 로고    scopus 로고
    • The predictive value of CD8, CD4, CD68, and human leukocyte antigen-D-related cells in the prognosis of cutaneous malignant melanoma with vertical growth phase
    • Piras F, Colombari R, Minerba L, Murtas D, Floris C, Maxia C et al. The predictive value of CD8, CD4, CD68, and human leukocyte antigen-D-related cells in the prognosis of cutaneous malignant melanoma with vertical growth phase. Cancer 2005; 104: 1246-1254.
    • (2005) Cancer , vol.104 , pp. 1246-1254
    • Piras, F.1    Colombari, R.2    Minerba, L.3    Murtas, D.4    Floris, C.5    Maxia, C.6
  • 12
    • 46049103179 scopus 로고    scopus 로고
    • Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression
    • van Houdt IS, Sluijter BJ, Moesbergen LM, Vos WM, de Gruijl TD, Molenkamp BG et al. Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression. Int J Cancer 2008; 123: 609-615.
    • (2008) Int J Cancer , vol.123 , pp. 609-615
    • Van Houdt, I.S.1    Sluijter, B.J.2    Moesbergen, L.M.3    Vos, W.M.4    De Gruijl, T.D.5    Molenkamp, B.G.6
  • 13
    • 38449103549 scopus 로고    scopus 로고
    • Utility of tumour-infiltrating CD25+ FOXP3+ regulatory T cell evaluation in predicting local recurrence in vertical growth phase cutaneous melanoma
    • Miracco C, Mourmouras V, Biagioli M, Rubegni P, Mannucci S, Monciatti I et al. Utility of tumour-infiltrating CD25+ FOXP3+ regulatory T cell evaluation in predicting local recurrence in vertical growth phase cutaneous melanoma. Oncol Rep 2007; 18: 1115-1122.
    • (2007) Oncol Rep , vol.18 , pp. 1115-1122
    • Miracco, C.1    Mourmouras, V.2    Biagioli, M.3    Rubegni, P.4    Mannucci, S.5    Monciatti, I.6
  • 14
    • 84892448554 scopus 로고    scopus 로고
    • Regulatory T cells in cancer immunotherapy
    • Nishikawa H, Sakaguchi S. Regulatory T cells in cancer immunotherapy. Curr Opin Immunol 2014; 27: 1-7.
    • (2014) Curr Opin Immunol , vol.27 , pp. 1-7
    • Nishikawa, H.1    Sakaguchi, S.2
  • 15
    • 84882637084 scopus 로고    scopus 로고
    • Tumor-associated macrophages: Functional diversity, clinical significance, and open questions
    • Biswas SK, Allavena P, Mantovani A. Tumor-associated macrophages: functional diversity, clinical significance, and open questions. Semin Immunopathol 2013; 35: 585-600.
    • (2013) Semin Immunopathol , vol.35 , pp. 585-600
    • Biswas, S.K.1    Allavena, P.2    Mantovani, A.3
  • 16
    • 0034650795 scopus 로고    scopus 로고
    • Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNFα and IL-1α
    • Torisu H, Ono M, Kiryu H, Furue M, Ohmoto Y, Nakayama J et al. Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFα and IL-1α. Int J Cancer 2000; 85: 182-188.
    • (2000) Int J Cancer , vol.85 , pp. 182-188
    • Torisu, H.1    Ono, M.2    Kiryu, H.3    Furue, M.4    Ohmoto, Y.5    Nakayama, J.6
  • 17
    • 27644590410 scopus 로고    scopus 로고
    • Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: Role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A
    • Varney ML, Johansson SL, Singh RK. Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A. Melanoma Res 2005; 15: 417-425.
    • (2005) Melanoma Res , vol.15 , pp. 417-425
    • Varney, M.L.1    Johansson, S.L.2    Singh, R.K.3
  • 18
    • 84927594692 scopus 로고    scopus 로고
    • BRAF inhibition stimulates melanoma-associated macrophages to drive tumor growth
    • Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A et al. BRAF inhibition stimulates melanoma-associated macrophages to drive tumor growth. Clin Cancer Res 2015; 21: 1652-1664.
    • (2015) Clin Cancer Res , vol.21 , pp. 1652-1664
    • Wang, T.1    Xiao, M.2    Ge, Y.3    Krepler, C.4    Belser, E.5    Lopez-Coral, A.6
  • 19
    • 69249222379 scopus 로고    scopus 로고
    • Polarization of tumorassociated neutrophil phenotype by TGF-β: 'N1' versus 'N2' TAN
    • Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L et al. Polarization of tumorassociated neutrophil phenotype by TGF-β: 'N1' versus 'N2' TAN. Cancer Cell 2009; 16: 183-194.
    • (2009) Cancer Cell , vol.16 , pp. 183-194
    • Fridlender, Z.G.1    Sun, J.2    Kim, S.3    Kapoor, V.4    Cheng, G.5    Ling, L.6
  • 21
    • 0037454776 scopus 로고    scopus 로고
    • Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8
    • Schaider H, Oka M, Bogenrieder T, Nesbit M, Satyamoorthy K, Berking C et al. Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8. Int J Cancer 2003; 103: 335-343.
    • (2003) Int J Cancer , vol.103 , pp. 335-343
    • Schaider, H.1    Oka, M.2    Bogenrieder, T.3    Nesbit, M.4    Satyamoorthy, K.5    Berking, C.6
  • 22
    • 84860220270 scopus 로고    scopus 로고
    • Intratumoral neutrophils and plasmacytoid dendritic cells indicate poor prognosis and are associated with pSTAT3 expression in AJCC stage I/II melanoma
    • Jensen TO, Schmidt H, Möller HJ, Donskov F, Höyer M, Sjoegren P et al. Intratumoral neutrophils and plasmacytoid dendritic cells indicate poor prognosis and are associated with pSTAT3 expression in AJCC stage I/II melanoma. Cancer 2012; 118: 2476-2485.
    • (2012) Cancer , vol.118 , pp. 2476-2485
    • Jensen, T.O.1    Schmidt, H.2    Möller, H.J.3    Donskov, F.4    Höyer, M.5    Sjoegren, P.6
  • 23
    • 25144493776 scopus 로고    scopus 로고
    • Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: A prognostic model
    • Schmidt H, Bastholt L, Geertsen P, Christensen IJ, Larsen S, Gehl J et al. Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: a prognostic model. Br J Cancer 2005; 93: 273-278.
    • (2005) Br J Cancer , vol.93 , pp. 273-278
    • Schmidt, H.1    Bastholt, L.2    Geertsen, P.3    Christensen, I.J.4    Larsen, S.5    Gehl, J.6
  • 24
    • 84954143592 scopus 로고    scopus 로고
    • Myeloid cells and related chronic inflammatory factors as novel predictive markers in melanoma treatment with ipilimumab
    • Gebhardt C, Sevko A, Jiang H, Lichtenberger R, Reith M, Tarnanidis K et al. Myeloid cells and related chronic inflammatory factors as novel predictive markers in melanoma treatment with ipilimumab. Clin Cancer Res 2015; 21: 5453-5459.
    • (2015) Clin Cancer Res , vol.21 , pp. 5453-5459
    • Gebhardt, C.1    Sevko, A.2    Jiang, H.3    Lichtenberger, R.4    Reith, M.5    Tarnanidis, K.6
  • 25
    • 84955607539 scopus 로고    scopus 로고
    • High neutrophil to lymphocyte ratio measured before starting ipilimumab treatment is associated with reduced overall survival in patients with melanoma
    • Zaragoza J, Caille A, Beneton N, Bens G, Christiann F, Maillard H et al. High neutrophil to lymphocyte ratio measured before starting ipilimumab treatment is associated with reduced overall survival in patients with melanoma. Br J Dermatol 2016; 174: 146-151.
    • (2016) Br J Dermatol , vol.174 , pp. 146-151
    • Zaragoza, J.1    Caille, A.2    Beneton, N.3    Bens, G.4    Christiann, F.5    Maillard, H.6
  • 26
    • 84880294344 scopus 로고    scopus 로고
    • Vemurafenib reverses immunosuppression by myeloid derived suppressor cells
    • Schilling B, Sucker A, Griewank K, Zhao F, Weide B, Görgens A et al. Vemurafenib reverses immunosuppression by myeloid derived suppressor cells. Int J Cancer 2013; 133: 1653-1663.
    • (2013) Int J Cancer , vol.133 , pp. 1653-1663
    • Schilling, B.1    Sucker, A.2    Griewank, K.3    Zhao, F.4    Weide, B.5    Görgens, A.6
  • 28
    • 84857219446 scopus 로고    scopus 로고
    • Monocytic CCR2+ myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment
    • Lesokhin AM, Hohl TM, Kitano S, Cortez C, Hirschhorn-Cymerman D, Avogadri F et al. Monocytic CCR2+ myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment. Cancer Res 2012; 72: 876-886.
    • (2012) Cancer Res , vol.72 , pp. 876-886
    • Lesokhin, A.M.1    Hohl, T.M.2    Kitano, S.3    Cortez, C.4    Hirschhorn-Cymerman, D.5    Avogadri, F.6
  • 29
    • 84945471772 scopus 로고    scopus 로고
    • How leukocytes cross the vascular endothelium
    • Vestweber D. How leukocytes cross the vascular endothelium. Nat Rev Immunol 2015; 15: 692-704.
    • (2015) Nat Rev Immunol , vol.15 , pp. 692-704
    • Vestweber, D.1
  • 30
    • 0031935954 scopus 로고    scopus 로고
    • Endothelial P-selectin expression is reduced in advanced primary melanoma and melanoma metastasis
    • Nooijen PT, Westphal JR, Eggermont AM, Schalkwijk C, Max R, de Waal RM et al. Endothelial P-selectin expression is reduced in advanced primary melanoma and melanoma metastasis. Am J Pathol 1998; 152: 679-682.
    • (1998) Am J Pathol , vol.152 , pp. 679-682
    • Nooijen, P.T.1    Westphal, J.R.2    Eggermont, A.M.3    Schalkwijk, C.4    Max, R.5    De Waal, R.M.6
  • 31
    • 0028924988 scopus 로고
    • Endothelial vascular cell adhesion molecule 1 expression is suppressed by melanoma and carcinoma
    • Piali L, Fichtel A, Terpe HJ, Imhof BA, Gisler RH. Endothelial vascular cell adhesion molecule 1 expression is suppressed by melanoma and carcinoma. J Exp Med 1995; 181: 811-816.
    • (1995) J Exp Med , vol.181 , pp. 811-816
    • Piali, L.1    Fichtel, A.2    Terpe, H.J.3    Imhof, B.A.4    Gisler, R.H.5
  • 33
    • 84962074569 scopus 로고    scopus 로고
    • Dynamic patterns of clonal evolution in tumor vasculature underlie alterations in lymphocyte-endothelial recognition to foster tumor immune escape
    • Corey DM, Rinkevich Y, Weissman IL. Dynamic patterns of clonal evolution in tumor vasculature underlie alterations in lymphocyte-endothelial recognition to foster tumor immune escape. Cancer Res 2016; 76: 1348-1353.
    • (2016) Cancer Res , vol.76 , pp. 1348-1353
    • Corey, D.M.1    Rinkevich, Y.2    Weissman, I.L.3
  • 34
    • 33845310374 scopus 로고    scopus 로고
    • Epigenetic regulation of tumor endothelial cell anergy: Silencing of intercellular adhesion molecule-1 by histone modifications
    • Hellebrekers DM, Castermans K, Vire E, Dings RP, Hoebers NT, Mayo KH et al. Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications. Cancer Res 2006; 66: 10770-10777.
    • (2006) Cancer Res , vol.66 , pp. 10770-10777
    • Hellebrekers, D.M.1    Castermans, K.2    Vire, E.3    Dings, R.P.4    Hoebers, N.T.5    Mayo, K.H.6
  • 35
    • 0037699015 scopus 로고    scopus 로고
    • Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression
    • Dirkx AE, Oude Egbrink MG, Kuijpers MJ, van der Niet ST, Heijnen VV, Bouma-ter Steege JC et al. Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression. Cancer Res 2003; 63: 2322-2329.
    • (2003) Cancer Res , vol.63 , pp. 2322-2329
    • Dirkx, A.E.1    Oude Egbrink, M.G.2    Kuijpers, M.J.3    Van Der Niet, S.T.4    Heijnen, V.V.5    Bouma-Ter Steege, J.C.6
  • 36
    • 79957921286 scopus 로고    scopus 로고
    • CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice
    • Wang L, Fan J, Thompson LF, Zhang Y, Shin T, Curiel TJ et al. CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice. J Clin Invest 2011; 121: 2371-2382.
    • (2011) J Clin Invest , vol.121 , pp. 2371-2382
    • Wang, L.1    Fan, J.2    Thompson, L.F.3    Zhang, Y.4    Shin, T.5    Curiel, T.J.6
  • 37
    • 0034880545 scopus 로고    scopus 로고
    • Leukocyte recruitment at sites of tumor: Dissonant orchestration
    • Carlos TM. Leukocyte recruitment at sites of tumor: dissonant orchestration. J Leukoc Biol 2001; 70: 171-184.
    • (2001) J Leukoc Biol , vol.70 , pp. 171-184
    • Carlos, T.M.1
  • 38
    • 0030014715 scopus 로고    scopus 로고
    • Melanoma-associated expression of transforming growth factor-beta isoforms
    • Van Belle P, Rodeck U, Nuamah I, Halpern AC, Elder DE. Melanoma-associated expression of transforming growth factor-beta isoforms. Am J Pathol 1996; 148: 1887.
    • (1996) Am J Pathol , vol.148 , pp. 1887
    • Van Belle, P.1    Rodeck, U.2    Nuamah, I.3    Halpern, A.C.4    Elder, D.E.5
  • 39
    • 75949093518 scopus 로고    scopus 로고
    • Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarrays
    • Mehnert JM, McCarthy MM, Jilaveanu L, Flaherty KT, Aziz S, Camp RL et al. Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarrays. Hum Pathol 2010; 41: 375-384.
    • (2010) Hum Pathol , vol.41 , pp. 375-384
    • Mehnert, J.M.1    McCarthy, M.M.2    Jilaveanu, L.3    Flaherty, K.T.4    Aziz, S.5    Camp, R.L.6
  • 40
    • 84922234972 scopus 로고    scopus 로고
    • Recurrence of melanoma following T cell treatment: Continued antigen expression in a tumor that evades T cell recruitment
    • Straetemans T, Berrevoets C, Coccoris M, Treffers-Westerlaken E, Wijers R, Cole DK et al. Recurrence of melanoma following T cell treatment: continued antigen expression in a tumor that evades T cell recruitment. Mol Ther 2015; 23: 396-406.
    • (2015) Mol Ther , vol.23 , pp. 396-406
    • Straetemans, T.1    Berrevoets, C.2    Coccoris, M.3    Treffers-Westerlaken, E.4    Wijers, R.5    Cole, D.K.6
  • 42
    • 38049000452 scopus 로고    scopus 로고
    • Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
    • Buckanovich RJ, Facciabene A, Kim S, Benencia F, Sasaroli D, Balint K et al. Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy. Nat Med 2008; 14: 28-36.
    • (2008) Nat Med , vol.14 , pp. 28-36
    • Buckanovich, R.J.1    Facciabene, A.2    Kim, S.3    Benencia, F.4    Sasaroli, D.5    Balint, K.6
  • 43
    • 84902124970 scopus 로고    scopus 로고
    • Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors
    • Motz GT, Santoro SP, Wang LP, Garrabrant T, Lastra RR, Hagemann IS et al. Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Nat Med 2014; 20: 607-615.
    • (2014) Nat Med , vol.20 , pp. 607-615
    • Motz, G.T.1    Santoro, S.P.2    Wang, L.P.3    Garrabrant, T.4    Lastra, R.R.5    Hagemann, I.S.6
  • 45
    • 80052236068 scopus 로고    scopus 로고
    • Human solid tumors contain high endothelial venules: Association with T-and B-lymphocyte infiltration and favorable prognosis in breast cancer
    • Martinet L, Garrido I, Filleron T, Le Guellec S, Bellard E, Fournie J-J et al. Human solid tumors contain high endothelial venules: association with T-and B-lymphocyte infiltration and favorable prognosis in breast cancer. Cancer Res 2011; 71: 5678-5687.
    • (2011) Cancer Res , vol.71 , pp. 5678-5687
    • Martinet, L.1    Garrido, I.2    Filleron, T.3    Le Guellec, S.4    Bellard, E.5    Fournie, J.-J.6
  • 46
    • 84887846709 scopus 로고    scopus 로고
    • Integrin CD11c/CD18 alpha-chain phosphorylation is functionally important
    • Uotila LM, Aatonen M, Gahmberg CG. Integrin CD11c/CD18 alpha-chain phosphorylation is functionally important. J Biol Chem 2013; 288: 33494-33499.
    • (2013) J Biol Chem , vol.288 , pp. 33494-33499
    • Uotila, L.M.1    Aatonen, M.2    Gahmberg, C.G.3
  • 47
    • 32644449297 scopus 로고    scopus 로고
    • Integrin αdβ2, an adhesion receptor up-regulated on macrophage foam cells, exhibits multiligand-binding properties
    • Yakubenko VP, Yadav SP, Ugarova TP. Integrin αDβ2, an adhesion receptor up-regulated on macrophage foam cells, exhibits multiligand-binding properties. Blood 2006; 107: 1643-1650.
    • (2006) Blood , vol.107 , pp. 1643-1650
    • Yakubenko, V.P.1    Yadav, S.P.2    Ugarova, T.P.3
  • 48
    • 42149133147 scopus 로고    scopus 로고
    • Role of galectin-3 in leukocyte recruitment in a murine model of lung infection by Streptococcus pneumoniae
    • Nieminen J, St-Pierre C, Bhaumik P, Poirier F, Sato S. Role of galectin-3 in leukocyte recruitment in a murine model of lung infection by Streptococcus pneumoniae. J Immunol 2008; 180: 2466-2473.
    • (2008) J Immunol , vol.180 , pp. 2466-2473
    • Nieminen, J.1    St-Pierre, C.2    Bhaumik, P.3    Poirier, F.4    Sato, S.5
  • 49
    • 0029845321 scopus 로고    scopus 로고
    • L1 adhesion molecule on human lymphocytes and monocytes: Expression and involvement in binding to αvβ3 integrin
    • Ebeling O, Duczmal A, Aigner S, Geiger C, Schöllhammer S, Kemshead JT et al. L1 adhesion molecule on human lymphocytes and monocytes: expression and involvement in binding to αvβ3 integrin. Eur J Immunol 1996; 26: 2508-2516.
    • (1996) Eur J Immunol , vol.26 , pp. 2508-2516
    • Ebeling, O.1    Duczmal, A.2    Aigner, S.3    Geiger, C.4    Schöllhammer, S.5    Kemshead, J.T.6
  • 50
    • 33646509028 scopus 로고    scopus 로고
    • Galectin-3 expression correlates with apoptosis of tumor-associated lymphocytes in human melanoma biopsies
    • Zubieta MR, Furman D, Barrio M, Bravo AI, Domenichini E, Mordoh J. Galectin-3 expression correlates with apoptosis of tumor-associated lymphocytes in human melanoma biopsies. Am J Pathol 2006; 168: 1666-1675.
    • (2006) Am J Pathol , vol.168 , pp. 1666-1675
    • Zubieta, M.R.1    Furman, D.2    Barrio, M.3    Bravo, A.I.4    Domenichini, E.5    Mordoh, J.6
  • 51
    • 77957355951 scopus 로고    scopus 로고
    • A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumorinfiltrating lymphocytes and favors tumor rejection in mice
    • Demotte N, Wieers G, Van Der Smissen P, Moser M, Schmidt C, Thielemans K et al. A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumorinfiltrating lymphocytes and favors tumor rejection in mice. Cancer Res 2010; 70: 7476-7488.
    • (2010) Cancer Res , vol.70 , pp. 7476-7488
    • Demotte, N.1    Wieers, G.2    Van Der Smissen, P.3    Moser, M.4    Schmidt, C.5    Thielemans, K.6
  • 52
    • 84932646690 scopus 로고    scopus 로고
    • Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints
    • Mikucki M, Fisher D, Matsuzaki J, Skitzki J, Gaulin N, Muhitch J et al. Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Nat Commun 2015; 6: 7458.
    • (2015) Nat Commun , vol.6 , pp. 7458
    • Mikucki, M.1    Fisher, D.2    Matsuzaki, J.3    Skitzki, J.4    Gaulin, N.5    Muhitch, J.6
  • 53
    • 80051703591 scopus 로고    scopus 로고
    • Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4+ and CD8+ T cells
    • González-Martín A, Gómez L, Lustgarten J, Mira E, Mañes S. Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4+ and CD8+ T cells. Cancer Res 2011; 71: 5455-5466.
    • (2011) Cancer Res , vol.71 , pp. 5455-5466
    • González-Martín, A.1    Gómez, L.2    Lustgarten, J.3    Mira, E.4    Mañes, S.5
  • 55
    • 81155154274 scopus 로고    scopus 로고
    • Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control
    • Hong M, Puaux A-L, Huang C, Loumagne L, Tow C, Mackay C et al. Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control. Cancer Res 2011; 71: 6997-7009.
    • (2011) Cancer Res , vol.71 , pp. 6997-7009
    • Hong, M.1    Puaux, A.-L.2    Huang, C.3    Loumagne, L.4    Tow, C.5    Mackay, C.6
  • 56
    • 84962032894 scopus 로고    scopus 로고
    • Melanoma induces, and adenosine suppresses, CXCR3-cognate chemokine production and T-cell infiltration of lungs bearing metastatic-like disease
    • Clancy-Thompson E, Perekslis TJ, Croteau W, Alexander MP, Chabanet TB, Turk MJ et al. Melanoma induces, and adenosine suppresses, CXCR3-cognate chemokine production and T-cell infiltration of lungs bearing metastatic-like disease. Cancer Immunol Res 2015; 3: 956-967.
    • (2015) Cancer Immunol Res , vol.3 , pp. 956-967
    • Clancy-Thompson, E.1    Perekslis, T.J.2    Croteau, W.3    Alexander, M.P.4    Chabanet, T.B.5    Turk, M.J.6
  • 57
    • 0032696574 scopus 로고    scopus 로고
    • Strong expression of the lymphoattractant C-X-C chemokine Mig is associated with heavy infiltration of T cells in human malignant melanoma
    • Kunz M, Toksoy A, Goebeler M, Engelhardt E, Bröcker EB, Gillitzer R. Strong expression of the lymphoattractant C-X-C chemokine Mig is associated with heavy infiltration of T cells in human malignant melanoma. J Pathol 1999; 189: 552-558.
    • (1999) J Pathol , vol.189 , pp. 552-558
    • Kunz, M.1    Toksoy, A.2    Goebeler, M.3    Engelhardt, E.4    Bröcker, E.B.5    Gillitzer, R.6
  • 58
    • 66149156276 scopus 로고    scopus 로고
    • Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment
    • Harlin H, Meng Y, Peterson AC, Zha Y, Tretiakova M, Slingluff C et al. Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment. Cancer Res 2009; 69: 3077-3085.
    • (2009) Cancer Res , vol.69 , pp. 3077-3085
    • Harlin, H.1    Meng, Y.2    Peterson, A.C.3    Zha, Y.4    Tretiakova, M.5    Slingluff, C.6
  • 60
    • 84887017053 scopus 로고    scopus 로고
    • CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2
    • Bedognetti D, Spivey TL, Zhao Y, Uccellini L, Tomei S, Dudley ME et al. CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2. Br J Cancer 2013; 109: 2412-2423.
    • (2013) Br J Cancer , vol.109 , pp. 2412-2423
    • Bedognetti, D.1    Spivey, T.L.2    Zhao, Y.3    Uccellini, L.4    Tomei, S.5    Dudley, M.E.6
  • 61
    • 7444247430 scopus 로고    scopus 로고
    • CXC chemokine receptor 3 expression by activated CD8+ T cells is associated with survival in melanoma patients with stage III disease
    • Mullins IM, Slingluff CL, Lee JK, Garbee CF, Shu J, Anderson SG et al. CXC chemokine receptor 3 expression by activated CD8+ T cells is associated with survival in melanoma patients with stage III disease. Cancer Res 2004; 64: 7697-7701.
    • (2004) Cancer Res , vol.64 , pp. 7697-7701
    • Mullins, I.M.1    Slingluff, C.L.2    Lee, J.K.3    Garbee, C.F.4    Shu, J.5    Anderson, S.G.6
  • 62
    • 84959879714 scopus 로고    scopus 로고
    • Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma
    • Jacquelot N, Enot DP, Flament C, Vimond N, Blattner C, Pitt JM et al. Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma. J Clin Invest 2016; 126: 921-937.
    • (2016) J Clin Invest , vol.126 , pp. 921-937
    • Jacquelot, N.1    Enot, D.P.2    Flament, C.3    Vimond, N.4    Blattner, C.5    Pitt, J.M.6
  • 63
    • 0035336409 scopus 로고    scopus 로고
    • Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells
    • Nesbit M, Schaider H, Miller TH, Herlyn M. Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells. J Immunol 2001; 166: 6483-6490.
    • (2001) J Immunol , vol.166 , pp. 6483-6490
    • Nesbit, M.1    Schaider, H.2    Miller, T.H.3    Herlyn, M.4
  • 64
    • 34447556692 scopus 로고    scopus 로고
    • Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft
    • Gazzaniga S, Bravo AI, Guglielmotti A, van Rooijen N, Maschi F, Vecchi A et al. Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J Invest Dermatol 2007; 127: 2031-2041.
    • (2007) J Invest Dermatol , vol.127 , pp. 2031-2041
    • Gazzaniga, S.1    Bravo, A.I.2    Guglielmotti, A.3    Van Rooijen, N.4    Maschi, F.5    Vecchi, A.6
  • 65
    • 80054694464 scopus 로고    scopus 로고
    • Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells
    • Molon B, Ugel S, Del Pozzo F, Soldani C, Zilio S, Avella D et al. Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells. J Exp Med 2011; 208: 1949-1962.
    • (2011) J Exp Med , vol.208 , pp. 1949-1962
    • Molon, B.1    Ugel, S.2    Del Pozzo, F.3    Soldani, C.4    Zilio, S.5    Avella, D.6
  • 66
    • 84891836500 scopus 로고    scopus 로고
    • CXCR2-mediated tumorassociated neutrophil recruitment is regulated by IFN-β
    • Jablonska J, Wu CF, Andzinski L, Leschner S, Weiss S. CXCR2-mediated tumorassociated neutrophil recruitment is regulated by IFN-β. Int J Cancer 2014; 134: 1346-1358.
    • (2014) Int J Cancer , vol.134 , pp. 1346-1358
    • Jablonska, J.1    Wu, C.F.2    Andzinski, L.3    Leschner, S.4    Weiss, S.5
  • 68
    • 31544456603 scopus 로고    scopus 로고
    • Distinct expression of CXCL8 and its receptors CXCR1 and CXCR2 and their association with vessel density and aggressiveness in malignant melanoma
    • Varney ML, Johansson SL, Singh RK. Distinct expression of CXCL8 and its receptors CXCR1 and CXCR2 and their association with vessel density and aggressiveness in malignant melanoma. Am J Clin Pathol 2006; 125: 209-216.
    • (2006) Am J Clin Pathol , vol.125 , pp. 209-216
    • Varney, M.L.1    Johansson, S.L.2    Singh, R.K.3
  • 69
    • 0034021278 scopus 로고    scopus 로고
    • Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
    • Leek RD, Hunt NC, Landers RJ, Lewis CE, Royds JA, Harris AL. Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. J Pathol 2000; 190: 430-436.
    • (2000) J Pathol , vol.190 , pp. 430-436
    • Leek, R.D.1    Hunt, N.C.2    Landers, R.J.3    Lewis, C.E.4    Royds, J.A.5    Harris, A.L.6
  • 70
    • 84870514368 scopus 로고    scopus 로고
    • Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma
    • Zhou S-L, Dai Z, Zhou Z-J, Wang X-Y, Yang G-H, Wang Z et al. Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma. Hepatology 2012; 56: 2242-2254.
    • (2012) Hepatology , vol.56 , pp. 2242-2254
    • Zhou, S.-L.1    Dai, Z.2    Zhou, Z.-J.3    Wang, X.-Y.4    Yang, G.-H.5    Wang, Z.6
  • 72
    • 0141996919 scopus 로고    scopus 로고
    • Platelet chemokines and chemokine receptors: Linking hemostasis, inflammation, and host defense
    • Gear AR, Camerini D. Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defense. Microcirculation 2003; 10: 335-350.
    • (2003) Microcirculation , vol.10 , pp. 335-350
    • Gear, A.R.1    Camerini, D.2
  • 73
    • 84905014848 scopus 로고    scopus 로고
    • Platelets guide the formation of early metastatic niches
    • Labelle M, Begum S, Hynes RO. Platelets guide the formation of early metastatic niches. Proc Natl Acad Sci USA 2014; 111: E3053-E3061.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E3053-E3061
    • Labelle, M.1    Begum, S.2    Hynes, R.O.3
  • 74
    • 84859305668 scopus 로고    scopus 로고
    • Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice
    • Gil-Bernabé AM, Ferjančič Š, Tlalka M, Zhao L, Allen PD, Im JH et al. Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice. Blood 2012; 119: 3164-3175.
    • (2012) Blood , vol.119 , pp. 3164-3175
    • Gil-Bernabé, A.M.1    Ferjančič, Š.2    Tlalka, M.3    Zhao, L.4    Allen, P.D.5    Im, J.H.6
  • 76
    • 84926525215 scopus 로고    scopus 로고
    • Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
    • Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E et al. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature 2015; 520: 373-377.
    • (2015) Nature , vol.520 , pp. 373-377
    • Twyman-Saint Victor, C.1    Rech, A.J.2    Maity, A.3    Rengan, R.4    Pauken, K.E.5    Stelekati, E.6
  • 77
    • 79955424620 scopus 로고    scopus 로고
    • Blood vessel maturation, vascular phenotype and angiogenic potential in malignant melanoma: One step forward for overcoming anti-angiogenic drug resistance?
    • Helfrich I, Schadendorf D. Blood vessel maturation, vascular phenotype and angiogenic potential in malignant melanoma: one step forward for overcoming anti-angiogenic drug resistance? Mol Oncol 2011; 5: 137-149.
    • (2011) Mol Oncol , vol.5 , pp. 137-149
    • Helfrich, I.1    Schadendorf, D.2
  • 78
    • 84928705533 scopus 로고    scopus 로고
    • VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation
    • Huang H, Langenkamp E, Georganaki M, Loskog A, Fuchs PF, Dieterich LC et al. VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation. FASEB J 2015; 29: 227-238.
    • (2015) FASEB J , vol.29 , pp. 227-238
    • Huang, H.1    Langenkamp, E.2    Georganaki, M.3    Loskog, A.4    Fuchs, P.F.5    Dieterich, L.C.6
  • 79
    • 84994097105 scopus 로고    scopus 로고
    • VEGF neutralization plus CTLA-4 blockade alters soluble and cellular factors associated with enhancing lymphocyte infiltration and humoral recognition in melanoma
    • Wu X, Giobbie-Hurder A, Liao X, Lawrence DP, McDermott DF, Zhou J et al. VEGF neutralization plus CTLA-4 blockade alters soluble and cellular factors associated with enhancing lymphocyte infiltration and humoral recognition in melanoma. Cancer Immunol Res 2016; 4: 858-868.
    • (2016) Cancer Immunol Res , vol.4 , pp. 858-868
    • Wu, X.1    Giobbie-Hurder, A.2    Liao, X.3    Lawrence, D.P.4    McDermott, D.F.5    Zhou, J.6
  • 80
    • 0036494443 scopus 로고    scopus 로고
    • Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication
    • Ganss R, Ryschich E, Klar E, Arnold B, Hämmerling GJ. Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Res 2002; 62: 1462-1470.
    • (2002) Cancer Res , vol.62 , pp. 1462-1470
    • Ganss, R.1    Ryschich, E.2    Klar, E.3    Arnold, B.4    Hämmerling, G.J.5
  • 81
    • 84887561907 scopus 로고    scopus 로고
    • Low-dose irradiation programs macrophage differentiation to an iNOS+/M1 phenotype that orchestrates effective T cell immunotherapy
    • Klug F, Prakash H, Huber Peter E, Seibel T, Bender N, Halama N et al. Low-dose irradiation programs macrophage differentiation to an iNOS+/M1 phenotype that orchestrates effective T cell immunotherapy. Cancer Cell 2013; 24: 589-602.
    • (2013) Cancer Cell , vol.24 , pp. 589-602
    • Klug, F.1    Prakash, H.2    Huber Peter, E.3    Seibel, T.4    Bender, N.5    Halama, N.6
  • 82
    • 84926507093 scopus 로고    scopus 로고
    • Three-year follow-up of advanced melanoma patients who received ipilimumab plus fotemustine in the Italian Network for Tumor Biotherapy (NIBIT)-M1 phase II study
    • Di Giacomo AM, Ascierto PA, Queirolo P, Pilla L, Ridolfi R, Santinami M et al. Three-year follow-up of advanced melanoma patients who received ipilimumab plus fotemustine in the Italian Network for Tumor Biotherapy (NIBIT)-M1 phase II study. Ann Oncol 2015; 26: 798-803.
    • (2015) Ann Oncol , vol.26 , pp. 798-803
    • Di Giacomo, A.M.1    Ascierto, P.A.2    Queirolo, P.3    Pilla, L.4    Ridolfi, R.5    Santinami, M.6
  • 84
    • 84872514398 scopus 로고    scopus 로고
    • BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice
    • Liu C, Peng W, Xu C, Lou Y, Zhang M, Wargo JA et al. BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clin Cancer Res 2013; 19: 393-403.
    • (2013) Clin Cancer Res , vol.19 , pp. 393-403
    • Liu, C.1    Peng, W.2    Xu, C.3    Lou, Y.4    Zhang, M.5    Wargo, J.A.6
  • 85
    • 84997666866 scopus 로고    scopus 로고
    • Phase II study of vemurafenib followed by ipilimumab in patients with previously untreated BRAF-mutated metastatic melanoma
    • Amin A, Lawson DH, Salama AKS, Koon HB, Guthrie T, Thomas SS et al. Phase II study of vemurafenib followed by ipilimumab in patients with previously untreated BRAF-mutated metastatic melanoma. J Immunother Cancer 2016; 4: 44.
    • (2016) J Immunother Cancer , vol.4 , pp. 44
    • Amin, A.1    Lawson, D.H.2    Salama, A.K.S.3    Koon, H.B.4    Guthrie, T.5    Thomas, S.S.6
  • 86
    • 84964313375 scopus 로고    scopus 로고
    • Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade
    • Cooper ZA, Juneja VR, Sage PT, Frederick DT, Piris A, Mitra D et al. Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade. Cancer Immunol Res 2014; 2: 643-654.
    • (2014) Cancer Immunol Res , vol.2 , pp. 643-654
    • Cooper, Z.A.1    Juneja, V.R.2    Sage, P.T.3    Frederick, D.T.4    Piris, A.5    Mitra, D.6
  • 87
    • 84917692849 scopus 로고    scopus 로고
    • BRAF and MEK inhibition variably affect GD2-specific chimeric antigen receptor (CAR) T-cell function in vitro
    • Gargett T, Fraser CK, Dotti G, Yvon ES, Brown MP. BRAF and MEK inhibition variably affect GD2-specific chimeric antigen receptor (CAR) T-cell function in vitro. J Immunother 2015; 38: 12-23.
    • (2015) J Immunother , vol.38 , pp. 12-23
    • Gargett, T.1    Fraser, C.K.2    Dotti, G.3    Yvon, E.S.4    Brown, M.P.5
  • 88
    • 84913604670 scopus 로고    scopus 로고
    • Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma model
    • Iannone R, Miele L, Maiolino P, Pinto A, Morello S. Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma model. Am J Cancer Res 2014; 4: 172-181.
    • (2014) Am J Cancer Res , vol.4 , pp. 172-181
    • Iannone, R.1    Miele, L.2    Maiolino, P.3    Pinto, A.4    Morello, S.5
  • 89
    • 84962921798 scopus 로고    scopus 로고
    • Facilitating T Cell infiltration in tumor microenvironment overcomes resistance to PD-L1 blockade
    • Tang H, Wang Y, Chlewicki LK, Zhang Y, Guo J, Liang W et al. Facilitating T Cell infiltration in tumor microenvironment overcomes resistance to PD-L1 blockade. Cancer Cell 2016; 29: 285-296.
    • (2016) Cancer Cell , vol.29 , pp. 285-296
    • Tang, H.1    Wang, Y.2    Chlewicki, L.K.3    Zhang, Y.4    Guo, J.5    Liang, W.6
  • 90
    • 78349255049 scopus 로고    scopus 로고
    • Transduction of tumorspecific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses
    • Peng W, Ye Y, Rabinovich BA, Liu C, Lou Y, Zhang M et al. Transduction of tumorspecific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses. Clin Cancer Res 2010; 16: 5458-5468.
    • (2010) Clin Cancer Res , vol.16 , pp. 5458-5468
    • Peng, W.1    Ye, Y.2    Rabinovich, B.A.3    Liu, C.4    Lou, Y.5    Zhang, M.6
  • 91
    • 79959705253 scopus 로고    scopus 로고
    • Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth
    • Tazzyman S, Barry ST, Ashton S, Wood P, Blakey D, Lewis CE et al. Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth. Int J Cancer 2011; 129: 847-858.
    • (2011) Int J Cancer , vol.129 , pp. 847-858
    • Tazzyman, S.1    Barry, S.T.2    Ashton, S.3    Wood, P.4    Blakey, D.5    Lewis, C.E.6
  • 93
    • 57749107585 scopus 로고    scopus 로고
    • Systemic blockade of transforming growth factor-β signaling augments the efficacy of immunogene therapy
    • Kim S, Buchlis G, Fridlender ZG, Sun J, Kapoor V, Cheng G et al. Systemic blockade of transforming growth factor-β signaling augments the efficacy of immunogene therapy. Cancer Res 2008; 68: 10247-10256.
    • (2008) Cancer Res , vol.68 , pp. 10247-10256
    • Kim, S.1    Buchlis, G.2    Fridlender, Z.G.3    Sun, J.4    Kapoor, V.5    Cheng, G.6
  • 95
    • 84959143338 scopus 로고    scopus 로고
    • Tumor vasculogenic mimicry predicts poor prognosis in cancer patients: A meta-analysis
    • Yang JP, Liao YD, Mai DM, Xie P, Qiang YY, Zheng LS et al. Tumor vasculogenic mimicry predicts poor prognosis in cancer patients: a meta-analysis. Angiogenesis 2016; 19: 191-200.
    • (2016) Angiogenesis , vol.19 , pp. 191-200
    • Yang, J.P.1    Liao, Y.D.2    Mai, D.M.3    Xie, P.4    Qiang, Y.Y.5    Zheng, L.S.6
  • 96
    • 84933057909 scopus 로고    scopus 로고
    • Induction of vasculogenic mimicry overrides VEGF-A silencing and enriches stem-like cancer cells in melanoma
    • Schnegg CI, Yang MH, Ghosh SK, Hsu M-Y. Induction of vasculogenic mimicry overrides VEGF-A silencing and enriches stem-like cancer cells in melanoma. Cancer Res 2015; 75: 1682-1690.
    • (2015) Cancer Res , vol.75 , pp. 1682-1690
    • Schnegg, C.I.1    Yang, M.H.2    Ghosh, S.K.3    Hsu, M.-Y.4
  • 97
    • 0036270898 scopus 로고    scopus 로고
    • The role of chemokines in melanoma tumor growth and metastasis
    • Payne AS, Cornelius LA. The role of chemokines in melanoma tumor growth and metastasis. J Invest Dermatol 2002; 118: 915-922.
    • (2002) J Invest Dermatol , vol.118 , pp. 915-922
    • Payne, A.S.1    Cornelius, L.A.2
  • 98
    • 0026717214 scopus 로고
    • A study of adhesion molecules as markers of progression in malignant melanoma
    • Denton KJ, Stretch JR, Gatter KC, Harris AL. A study of adhesion molecules as markers of progression in malignant melanoma. J Pathol 1992; 167: 187-191.
    • (1992) J Pathol , vol.167 , pp. 187-191
    • Denton, K.J.1    Stretch, J.R.2    Gatter, K.C.3    Harris, A.L.4
  • 99
    • 79958863561 scopus 로고    scopus 로고
    • A novel function of junctional adhesion molecule-C in mediating melanoma cell metastasis
    • Langer HF, Orlova VV, Xie C, Kaul S, Schneider D, Lonsdorf AS et al. A novel function of junctional adhesion molecule-C in mediating melanoma cell metastasis. Cancer Res 2011; 71: 4096-4105.
    • (2011) Cancer Res , vol.71 , pp. 4096-4105
    • Langer, H.F.1    Orlova, V.V.2    Xie, C.3    Kaul, S.4    Schneider, D.5    Lonsdorf, A.S.6


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