-
1
-
-
79952613370
-
Systematic review of medical treatment in melanoma: Current status and future prospects
-
1:CAS:528:DC%2BC3MXisV2qtLw%3D 21212434 10.1634/theoncologist.2010-0190
-
Garbe C, Eigentler TK, Keilholz U, Hauschild A, Kirkwood JM (2011) Systematic review of medical treatment in melanoma: current status and future prospects. Oncologist 16(1):5-24
-
(2011)
Oncologist
, vol.16
, Issue.1
, pp. 5-24
-
-
Garbe, C.1
Eigentler, T.K.2
Keilholz, U.3
Hauschild, A.4
Kirkwood, J.M.5
-
2
-
-
65249173447
-
Adoptive cell therapy for the treatment of patients with metastatic melanoma
-
1:CAS:528:DC%2BD1MXlsVCgtb8%3D 3459355 19304471 10.1016/j.coi.2009.03.002
-
Rosenberg SA, Dudley ME (2009) Adoptive cell therapy for the treatment of patients with metastatic melanoma. Curr Opin Immunol 21(2):233-240
-
(2009)
Curr Opin Immunol
, vol.21
, Issue.2
, pp. 233-240
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
3
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
-
1:CAS:528:DyaK1MXkvVSmur4%3D 10561265
-
Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, Abrams J, Sznol M, Parkinson D, Hawkins M, Paradise C, Kunkel L, Rosenberg SA (1999) High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 17(7):2105-2116
-
(1999)
J Clin Oncol
, vol.17
, Issue.7
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
Fisher, R.I.4
Weiss, G.5
Margolin, K.6
Abrams, J.7
Sznol, M.8
Parkinson, D.9
Hawkins, M.10
Paradise, C.11
Kunkel, L.12
Rosenberg, S.A.13
-
4
-
-
84863116743
-
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
-
1:CAS:528:DC%2BC38XjtFOqtr0%3D 3724515 22356324 10.1056/NEJMoa1112302
-
Sosman JA, Kim KB, Schuchter L, Gonzalez R, Pavlick AC, Weber JS, McArthur GA, Hutson TE, Moschos SJ, Flaherty KT, Hersey P, Kefford R, Lawrence D, Puzanov I, Lewis KD, Amaravadi RK, Chmielowski B, Lawrence HJ, Shyr Y, Ye F, Li J, Nolop KB, Lee RJ, Joe AK, Ribas A (2012) Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med 366(8):707-714
-
(2012)
N Engl J Med
, vol.366
, Issue.8
, pp. 707-714
-
-
Sosman, J.A.1
Kim, K.B.2
Schuchter, L.3
Gonzalez, R.4
Pavlick, A.C.5
Weber, J.S.6
McArthur, G.A.7
Hutson, T.E.8
Moschos, S.J.9
Flaherty, K.T.10
Hersey, P.11
Kefford, R.12
Lawrence, D.13
Puzanov, I.14
Lewis, K.D.15
Amaravadi, R.K.16
Chmielowski, B.17
Lawrence, H.J.18
Shyr, Y.19
Ye, F.20
Li, J.21
Nolop, K.B.22
Lee, R.J.23
Joe, A.K.24
Ribas, A.25
more..
-
5
-
-
84863673204
-
Improved survival with MEK inhibition in BRAF-mutated melanoma
-
1:CAS:528:DC%2BC38XhtFKjs7zN 22663011 10.1056/NEJMoa1203421
-
Flaherty KT, Robert C, Hersey P, Nathan P, Garbe C, Milhem M, Demidov LV, Hassel JC, Rutkowski P, Mohr P, Dummer R, Trefzer U, Larkin JM, Utikal J, Dreno B, Nyakas M, Middleton MR, Becker JC, Casey M, Sherman LJ, Wu FS, Ouellet D, Martin AM, Patel K, Schadendorf D (2012) Improved survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med 367(2):107-114
-
(2012)
N Engl J Med
, vol.367
, Issue.2
, pp. 107-114
-
-
Flaherty, K.T.1
Robert, C.2
Hersey, P.3
Nathan, P.4
Garbe, C.5
Milhem, M.6
Demidov, L.V.7
Hassel, J.C.8
Rutkowski, P.9
Mohr, P.10
Dummer, R.11
Trefzer, U.12
Larkin, J.M.13
Utikal, J.14
Dreno, B.15
Nyakas, M.16
Middleton, M.R.17
Becker, J.C.18
Casey, M.19
Sherman, L.J.20
Wu, F.S.21
Ouellet, D.22
Martin, A.M.23
Patel, K.24
Schadendorf, D.25
more..
-
6
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
1:CAS:528:DC%2BC3MXosVeitbs%3D 3549296 21639808 10.1056/NEJMoa1103782
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, O'Day SJ, Sosman JA, Kirkwood JM, Eggermont AM, Dreno B, Nolop K, Li J, Nelson B, Hou J, Lee RJ, Flaherty KT, McArthur GA (2011) Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 364(26):2507-2516
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
Dummer, R.7
Garbe, C.8
Testori, A.9
Maio, M.10
Hogg, D.11
Lorigan, P.12
Lebbe, C.13
Jouary, T.14
Schadendorf, D.15
Ribas, A.16
O'Day, S.J.17
Sosman, J.A.18
Kirkwood, J.M.19
Eggermont, A.M.20
Dreno, B.21
Nolop, K.22
Li, J.23
Nelson, B.24
Hou, J.25
Lee, R.J.26
Flaherty, K.T.27
McArthur, G.A.28
more..
-
7
-
-
84868224906
-
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
-
1:CAS:528:DC%2BC38Xhs1eksLrJ 3549295 23020132 10.1056/NEJMoa1210093
-
Flaherty KT, Infante JR, Daud A, Gonzalez R, Kefford RF, Sosman J, Hamid O, Schuchter L, Cebon J, Ibrahim N, Kudchadkar R, Burris HA 3rd, Falchook G, Algazi A, Lewis K, Long GV, Puzanov I, Lebowitz P, Singh A, Little S, Sun P, Allred A, Ouellet D, Kim KB, Patel K, Weber J (2012) Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 367(18):1694-1703
-
(2012)
N Engl J Med
, vol.367
, Issue.18
, pp. 1694-1703
-
-
Flaherty, K.T.1
Infante, J.R.2
Daud, A.3
Gonzalez, R.4
Kefford, R.F.5
Sosman, J.6
Hamid, O.7
Schuchter, L.8
Cebon, J.9
Ibrahim, N.10
Kudchadkar, R.11
Burris III, H.A.12
Falchook, G.13
Algazi, A.14
Lewis, K.15
Long, G.V.16
Puzanov, I.17
Lebowitz, P.18
Singh, A.19
Little, S.20
Sun, P.21
Allred, A.22
Ouellet, D.23
Kim, K.B.24
Patel, K.25
Weber, J.26
more..
-
8
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
1:CAS:528:DC%2BC3cXhtVCrtrbN 3549297 20525992 10.1056/NEJMoa1003466
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbe C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ (2010) Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363(8):711-723
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerley, W.11
Van Den Eertwegh, A.J.12
Lutzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbe, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
9
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
1:CAS:528:DC%2BC3MXosVegtro%3D 21639810 10.1056/NEJMoa1104621
-
Robert C, Thomas L, Bondarenko I, O'Day S, M D J, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Jr Miller WH, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD (2011) Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 364(26):2517-2526
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Garbe, C.5
Lebbe, C.6
Baurain, J.F.7
Testori, A.8
Grob, J.J.9
Davidson, N.10
Richards, J.11
Maio, M.12
Hauschild, A.13
Miller Jr., W.H.14
Gascon, P.15
Lotem, M.16
Harmankaya, K.17
Ibrahim, R.18
Francis, S.19
Chen, T.T.20
Humphrey, R.21
Hoos, A.22
Wolchok, J.D.23
more..
-
10
-
-
79957917538
-
Ipilimumab
-
1:CAS:528:DC%2BC3MXmvVegsbk%3D 21629286 10.1038/nrd3463
-
Sondak VK, Smalley KS, Kudchadkar R, Grippon S, Kirkpatrick P (2011) Ipilimumab. Nat Rev Drug Discov 10(6):411-412
-
(2011)
Nat Rev Drug Discov
, vol.10
, Issue.6
, pp. 411-412
-
-
Sondak, V.K.1
Smalley, K.S.2
Kudchadkar, R.3
Grippon, S.4
Kirkpatrick, P.5
-
11
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
1:CAS:528:DC%2BC38XksVegtrw%3D 22437870 10.1038/nrc3239
-
Pardoll DM (2012) The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12(4):252-264
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
12
-
-
79957925314
-
Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
-
1:CAS:528:DC%2BC3MXnsVaitrw%3D 3104769 21555851 10.1172/JCI46102
-
Baitsch L, Baumgaertner P, Devevre E, Raghav SK, Legat A, Barba L, Wieckowski S, Bouzourene H, Deplancke B, Romero P, Rufer N, Speiser DE (2011) Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients. J Clin Invest 121(6):2350-2360
-
(2011)
J Clin Invest
, vol.121
, Issue.6
, pp. 2350-2360
-
-
Baitsch, L.1
Baumgaertner, P.2
Devevre, E.3
Raghav, S.K.4
Legat, A.5
Barba, L.6
Wieckowski, S.7
Bouzourene, H.8
Deplancke, B.9
Romero, P.10
Rufer, N.11
Speiser, D.E.12
-
13
-
-
84155163015
-
Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma
-
10.1097/CJI.0b013e31823aa41c
-
Weber JS, Hamid O, Chasalow SD, Wu DY, Parker SM, Galbraith S, Gnjatic S, Berman D (2011) Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma. J Immunother 35(1):89-97
-
(2011)
J Immunother
, vol.35
, Issue.1
, pp. 89-97
-
-
Weber, J.S.1
Hamid, O.2
Chasalow, S.D.3
Wu, D.Y.4
Parker, S.M.5
Galbraith, S.6
Gnjatic, S.7
Berman, D.8
-
14
-
-
84863672266
-
Biomarkers on melanoma patient T cells associated with ipilimumab treatment
-
1:CAS:528:DC%2BC3sXitVynsL0%3D 3527361 22788688 10.1186/1479-5876-10-146
-
Wang W, Yu D, Sarnaik AA, Yu B, Hall M, Morelli D, Zhang Y, Zhao X, Weber JS (2012) Biomarkers on melanoma patient T cells associated with ipilimumab treatment. J Transl Med 10(1):146-158
-
(2012)
J Transl Med
, vol.10
, Issue.1
, pp. 146-158
-
-
Wang, W.1
Yu, D.2
Sarnaik, A.A.3
Yu, B.4
Hall, M.5
Morelli, D.6
Zhang, Y.7
Zhao, X.8
Weber, J.S.9
-
15
-
-
24944459890
-
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
-
1:CAS:528:DC%2BD2MXhtVKgtb3L 1473965 16087944 10.1200/JCO.2005.06.205
-
Attia P, Phan GQ, Maker AV, Robinson MR, Quezado MM, Yang JC, Sherry RM, Topalian SL, Kammula US, Royal RE, Restifo NP, Haworth LR, Levy C, Mavroukakis SA, Nichol G, Yellin MJ, Rosenberg SA (2005) Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 23(25):6043-6053
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 6043-6053
-
-
Attia, P.1
Phan, G.Q.2
Maker, A.V.3
Robinson, M.R.4
Quezado, M.M.5
Yang, J.C.6
Sherry, R.M.7
Topalian, S.L.8
Kammula, U.S.9
Royal, R.E.10
Restifo, N.P.11
Haworth, L.R.12
Levy, C.13
Mavroukakis, S.A.14
Nichol, G.15
Yellin, M.J.16
Rosenberg, S.A.17
-
16
-
-
77955874663
-
Treating cancer by targeting the immune system
-
1:CAS:528:DC%2BC3cXhtVCrtbrK 20818880 10.1056/NEJMe1006416
-
Hwu P (2010) Treating cancer by targeting the immune system. N Engl J Med 363(8):779-781
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 779-781
-
-
Hwu, P.1
-
17
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
-
1:CAS:528:DC%2BD1MXhsFSnu7vN 19934295 10.1158/1078-0432.CCR-09-1624
-
Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbe C, Maio M, Binder M, Bohnsack O, Nichol G, Humphrey R, Hodi FS (2009) Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res 15(23):7412-7420
-
(2009)
Clin Cancer Res
, vol.15
, Issue.23
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O'Day, S.3
Weber, J.S.4
Hamid, O.5
Lebbe, C.6
Maio, M.7
Binder, M.8
Bohnsack, O.9
Nichol, G.10
Humphrey, R.11
Hodi, F.S.12
-
18
-
-
77950258677
-
Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: Lymphocyte count after 2 doses correlates with survival
-
1:CAS:528:DC%2BC3cXkvFOns7g%3D 2917065 20143434 10.1002/cncr.24951
-
Ku GY, Yuan J, Page DB, Schroeder SE, Panageas KS, Carvajal RD, Chapman PB, Schwartz GK, Allison JP, Wolchok JD (2010) Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: lymphocyte count after 2 doses correlates with survival. Cancer 116(7):1767-1775
-
(2010)
Cancer
, vol.116
, Issue.7
, pp. 1767-1775
-
-
Ku, G.Y.1
Yuan, J.2
Page, D.B.3
Schroeder, S.E.4
Panageas, K.S.5
Carvajal, R.D.6
Chapman, P.B.7
Schwartz, G.K.8
Allison, J.P.9
Wolchok, J.D.10
-
19
-
-
77952337834
-
Preoperative CTLA-4 blockade: Tolerability and immune monitoring in the setting of a presurgical clinical trial
-
1:CAS:528:DC%2BC3cXlvF2hsrY%3D 2919850 20460488 10.1158/1078-0432.CCR-10- 0569
-
Carthon BC, Wolchok JD, Yuan J, Kamat A, Ng Tang DS, Sun J, Ku G, Troncoso P, Logothetis CJ, Allison JP, Sharma P (2010) Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 16(10):2861-2871
-
(2010)
Clin Cancer Res
, vol.16
, Issue.10
, pp. 2861-2871
-
-
Carthon, B.C.1
Wolchok, J.D.2
Yuan, J.3
Kamat, A.4
Ng Tang, D.S.5
Sun, J.6
Ku, G.7
Troncoso, P.8
Logothetis, C.J.9
Allison, J.P.10
Sharma, P.11
-
20
-
-
84878875962
-
Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10 mg/kg within an expanded access programme
-
23591982 10.1007/s00262-013-1418-6
-
Di Giacomo AM, Calabro L, Danielli R, Fonsatti E, Bertocci E, Pesce I, Fazio C, Cutaia O, Giannarelli D, Miracco C, Biagioli M, Altomonte M, Maio M (2013) Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10 mg/kg within an expanded access programme. Cancer Immunol Immunother 62(6):1021-1028
-
(2013)
Cancer Immunol Immunother
, vol.62
, Issue.6
, pp. 1021-1028
-
-
Di Giacomo, A.M.1
Calabro, L.2
Danielli, R.3
Fonsatti, E.4
Bertocci, E.5
Pesce, I.6
Fazio, C.7
Cutaia, O.8
Giannarelli, D.9
Miracco, C.10
Biagioli, M.11
Altomonte, M.12
Maio, M.13
-
21
-
-
80053648839
-
Integrated NY-ESO-1 antibody and CD8 + T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
-
1:CAS:528:DC%2BC3MXhtlWksrbK 21933959 10.1073/pnas.1110814108
-
Yuan J, Adamow M, Ginsberg BA, Rasalan TS, Ritter E, Gallardo HF, Xu Y, Pogoriler E, Terzulli SL, Kuk D, Panageas KS, Ritter G, Sznol M, Halaban R, Jungbluth AA, Allison JP, Old LJ, Wolchok JD, Gnjatic S (2011) Integrated NY-ESO-1 antibody and CD8 + T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab. Proc Natl Acad Sci USA 108(40):16723-16728
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.40
, pp. 16723-16728
-
-
Yuan, J.1
Adamow, M.2
Ginsberg, B.A.3
Rasalan, T.S.4
Ritter, E.5
Gallardo, H.F.6
Xu, Y.7
Pogoriler, E.8
Terzulli, S.L.9
Kuk, D.10
Panageas, K.S.11
Ritter, G.12
Sznol, M.13
Halaban, R.14
Jungbluth, A.A.15
Allison, J.P.16
Old, L.J.17
Wolchok, J.D.18
Gnjatic, S.19
-
22
-
-
79960895501
-
CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: Three cases
-
1:CAS:528:DC%2BC3MXpt1OqsbY%3D 3654853 21465316 10.1007/s00262-011-1011-9
-
Yuan J, Ginsberg B, Page D, Li Y, Rasalan T, Gallardo HF, Xu Y, Adams S, Bhardwaj N, Busam K, Old LJ, Allison JP, Jungbluth A, Wolchok JD (2011) CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases. Cancer Immunol Immunother 60(8):1137-1146
-
(2011)
Cancer Immunol Immunother
, vol.60
, Issue.8
, pp. 1137-1146
-
-
Yuan, J.1
Ginsberg, B.2
Page, D.3
Li, Y.4
Rasalan, T.5
Gallardo, H.F.6
Xu, Y.7
Adams, S.8
Bhardwaj, N.9
Busam, K.10
Old, L.J.11
Allison, J.P.12
Jungbluth, A.13
Wolchok, J.D.14
-
23
-
-
54449091476
-
CTLA-4 blockade increases IFNgamma-producing CD4 + ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
-
1:CAS:528:DC%2BD1cXht1aqurzI 18818309 10.1073/pnas.0806075105
-
Liakou CI, Kamat A, Tang DN, Chen H, Sun J, Troncoso P, Logothetis C, Sharma P (2008) CTLA-4 blockade increases IFNgamma-producing CD4 + ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients. Proc Natl Acad Sci USA 105(39):14987-14992
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.39
, pp. 14987-14992
-
-
Liakou, C.I.1
Kamat, A.2
Tang, D.N.3
Chen, H.4
Sun, J.5
Troncoso, P.6
Logothetis, C.7
Sharma, P.8
-
24
-
-
78651072784
-
Single dose of anti-CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
-
21173239 10.1073/pnas.1016791108
-
Pedicord VA, Montalvo W, Leiner IM, Allison JP (2010) Single dose of anti-CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance. Proc Natl Acad Sci USA 108(1):266-271
-
(2010)
Proc Natl Acad Sci USA
, vol.108
, Issue.1
, pp. 266-271
-
-
Pedicord, V.A.1
Montalvo, W.2
Leiner, I.M.3
Allison, J.P.4
-
25
-
-
79955723632
-
Myeloid derived suppressor cells in human diseases
-
1:CAS:528:DC%2BC3MXntVyjurk%3D 3478130 21237299 10.1016/j.intimp.2011.01. 003
-
Greten TF, Manns MP, Korangy F (2011) Myeloid derived suppressor cells in human diseases. Int Immunopharmacol 11(7):802-807
-
(2011)
Int Immunopharmacol
, vol.11
, Issue.7
, pp. 802-807
-
-
Greten, T.F.1
Manns, M.P.2
Korangy, F.3
-
26
-
-
84856706929
-
Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients
-
22120756 10.1007/s00262-011-1161-9
-
Filipazzi P, Huber V, Rivoltini L (2011) Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients. Cancer Immunol Immunother 61(2):255-263
-
(2011)
Cancer Immunol Immunother
, vol.61
, Issue.2
, pp. 255-263
-
-
Filipazzi, P.1
Huber, V.2
Rivoltini, L.3
-
27
-
-
77957991455
-
Myeloid-derived suppressor cells in human cancer
-
1:CAS:528:DC%2BC3cXhtFGnurjM 20693846 10.1097/PPO.0b013e3181eb3358
-
Nagaraj S, Gabrilovich DI (2010) Myeloid-derived suppressor cells in human cancer. Cancer J 16(4):348-353
-
(2010)
Cancer J
, vol.16
, Issue.4
, pp. 348-353
-
-
Nagaraj, S.1
Gabrilovich, D.I.2
-
28
-
-
84865715288
-
Neutrophils and granulocytic myeloid-derived suppressor cells: Immunophenotyping, cell biology and clinical relevance in human oncology
-
1:CAS:528:DC%2BC38XhtVOhtL%2FK 22692756 10.1007/s00262-012-1294-5
-
Dumitru CA, Moses K, Trellakis S, Lang S, Brandau S (2012) Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology. Cancer Immunol Immunother 61(8):1155-1167
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.8
, pp. 1155-1167
-
-
Dumitru, C.A.1
Moses, K.2
Trellakis, S.3
Lang, S.4
Brandau, S.5
-
29
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
1:CAS:528:DC%2BC38XksVensrs%3D 3587148 22437938 10.1038/nri3175
-
Gabrilovich DI, Ostrand-Rosenberg S, Bronte V (2012) Coordinated regulation of myeloid cells by tumours. Nat Rev Immunol 12(4):253-268
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.4
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
30
-
-
77953141534
-
Immature immunosuppressive CD14 + HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign
-
1:CAS:528:DC%2BC3cXmslWgsbY%3D 20484028 10.1158/0008-5472.CAN-09-3767
-
Poschke I, Mougiakakos D, Hansson J, Masucci GV, Kiessling R (2010) Immature immunosuppressive CD14 + HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign. Cancer Res 70(11):4335-4345
-
(2010)
Cancer Res
, vol.70
, Issue.11
, pp. 4335-4345
-
-
Poschke, I.1
Mougiakakos, D.2
Hansson, J.3
Masucci, G.V.4
Kiessling, R.5
-
31
-
-
34447258415
-
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
-
1:CAS:528:DC%2BD2sXotV2mt7Y%3D 17577033 10.1200/JCO.2006.08.5829
-
Filipazzi P, Valenti R, Huber V, Pilla L, Canese P, Iero M, Castelli C, Mariani L, Parmiani G, Rivoltini L (2007) Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol 25(18):2546-2553
-
(2007)
J Clin Oncol
, vol.25
, Issue.18
, pp. 2546-2553
-
-
Filipazzi, P.1
Valenti, R.2
Huber, V.3
Pilla, L.4
Canese, P.5
Iero, M.6
Castelli, C.7
Mariani, L.8
Parmiani, G.9
Rivoltini, L.10
-
32
-
-
84866910216
-
Myeloid cells obtained from the blood but not from the tumor can suppress T cell proliferation in patients with melanoma
-
1:CAS:528:DC%2BC38XhsFSgtbnK 22837179 10.1158/1078-0432.CCR-12-1108
-
Gros A, Turcotte S, Ahmadzadeh M, Wunderlich JR, Dudley ME, Rosenberg SA (2012) Myeloid cells obtained from the blood but not from the tumor can suppress T cell proliferation in patients with melanoma. Clin Cancer Res 18(19):5212-5223
-
(2012)
Clin Cancer Res
, vol.18
, Issue.19
, pp. 5212-5223
-
-
Gros, A.1
Turcotte, S.2
Ahmadzadeh, M.3
Wunderlich, J.R.4
Dudley, M.E.5
Rosenberg, S.A.6
-
33
-
-
58149332680
-
Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma
-
1:CAS:528:DC%2BD1cXhsV2it7jF 19088044 10.1158/1078-0432.CCR-08-0165
-
Kusmartsev S, Su Z, Heiser A, Dannull J, Eruslanov E, Kubler H, Yancey D, Dahm P, Vieweg J (2008) Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin Cancer Res 14(24):8270-8278
-
(2008)
Clin Cancer Res
, vol.14
, Issue.24
, pp. 8270-8278
-
-
Kusmartsev, S.1
Su, Z.2
Heiser, A.3
Dannull, J.4
Eruslanov, E.5
Kubler, H.6
Yancey, D.7
Dahm, P.8
Vieweg, J.9
-
34
-
-
33749461167
-
All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients
-
1:CAS:528:DC%2BD28Xps1ahsrk%3D 1586106 16982775 10.1158/0008-5472.CAN-06- 1690
-
Mirza N, Fishman M, Fricke I, Dunn M, Neuger AM, Frost TJ, Lush RM, Antonia S, Gabrilovich DI (2006) All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients. Cancer Res 66(18):9299-9307
-
(2006)
Cancer Res
, vol.66
, Issue.18
, pp. 9299-9307
-
-
Mirza, N.1
Fishman, M.2
Fricke, I.3
Dunn, M.4
Neuger, A.M.5
Frost, T.J.6
Lush, R.M.7
Antonia, S.8
Gabrilovich, D.I.9
-
35
-
-
53249111806
-
Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c + dendritic cell frequency predicts progression-free survival
-
18794101 10.1158/1078-0432.CCR-08-0656
-
van Cruijsen H, van der Veldt AA, Vroling L, Oosterhoff D, Broxterman HJ, Scheper RJ, Giaccone G, Haanen JB, van den Eertwegh AJ, Boven E, Hoekman K, de Gruijl TD (2008) Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c + dendritic cell frequency predicts progression-free survival. Clin Cancer Res 14(18):5884-5892
-
(2008)
Clin Cancer Res
, vol.14
, Issue.18
, pp. 5884-5892
-
-
Van Cruijsen, H.1
Van Der Veldt, A.A.2
Vroling, L.3
Oosterhoff, D.4
Broxterman, H.J.5
Scheper, R.J.6
Giaccone, G.7
Haanen, J.B.8
Van Den Eertwegh, A.J.9
Boven, E.10
Hoekman, K.11
De Gruijl, T.D.12
-
36
-
-
84857205712
-
Antigen-specific CD4 + T cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signaling
-
1:CAS:528:DC%2BC38XitlGit7Y%3D 22237629 10.1158/0008-5472.CAN-11-2863
-
Nagaraj S, Nelson A, Youn JI, Cheng P, Quiceno D, Gabrilovich DI (2012) Antigen-specific CD4 + T cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signaling. Cancer Res 72(4):928-938
-
(2012)
Cancer Res
, vol.72
, Issue.4
, pp. 928-938
-
-
Nagaraj, S.1
Nelson, A.2
Youn, J.I.3
Cheng, P.4
Quiceno, D.5
Gabrilovich, D.I.6
-
37
-
-
4544309074
-
TCR zeta-chain downregulation: Curtailing an excessive inflammatory immune response
-
1:CAS:528:DC%2BD2cXntFCmt7Y%3D 15343367 10.1038/nri1434
-
Baniyash M (2004) TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response. Nat Rev Immunol 4(9):675-687
-
(2004)
Nat Rev Immunol
, vol.4
, Issue.9
, pp. 675-687
-
-
Baniyash, M.1
-
38
-
-
82255192901
-
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
-
1:CAS:528:DC%2BC3MXhsFeitL%2FF 22116087 10.1038/nri3108
-
Walker LS, Sansom DM (2011) The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nat Rev Immunol 11(12):852-863
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.12
, pp. 852-863
-
-
Walker, L.S.1
Sansom, D.M.2
-
39
-
-
84862120892
-
Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner
-
1:CAS:528:DC%2BC38Xht1ajsrjJ 3386478 22283566 10.3109/1547691X.2011. 642418
-
Michels T, Shurin GV, Naiditch H, Sevko A, Umansky V, Shurin MR (2012) Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner. J Immunotoxicol 9(3):292-300
-
(2012)
J Immunotoxicol
, vol.9
, Issue.3
, pp. 292-300
-
-
Michels, T.1
Shurin, G.V.2
Naiditch, H.3
Sevko, A.4
Umansky, V.5
Shurin, M.R.6
-
40
-
-
33847258205
-
Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
-
1:STN:280:DC%2BD2s%2Fotlekug%3D%3D 17116643 10.1093/annonc/mdl158
-
Parmiani G, Castelli C, Pilla L, Santinami M, Colombo MP, Rivoltini L (2007) Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann Oncol 18(2):226-232
-
(2007)
Ann Oncol
, vol.18
, Issue.2
, pp. 226-232
-
-
Parmiani, G.1
Castelli, C.2
Pilla, L.3
Santinami, M.4
Colombo, M.P.5
Rivoltini, L.6
-
41
-
-
79961167639
-
Targeting myeloid regulatory cells in cancer by chemotherapeutic agents
-
1:CAS:528:DC%2BC3MXptFaisrs%3D 21717082 10.1007/s12026-011-8213-2
-
Naiditch H, Shurin MR, Shurin GV (2011) Targeting myeloid regulatory cells in cancer by chemotherapeutic agents. Immunol Res 50(2-3):276-285
-
(2011)
Immunol Res
, vol.50
, Issue.2-3
, pp. 276-285
-
-
Naiditch, H.1
Shurin, M.R.2
Shurin, G.V.3
-
42
-
-
78649604938
-
The growing diversity and spectrum of action of myeloid-derived suppressor cells
-
1:CAS:528:DC%2BC3cXhsVOktbnM 21110315 10.1002/eji.201041170
-
Mantovani A (2010) The growing diversity and spectrum of action of myeloid-derived suppressor cells. Eur J Immunol 40(12):3317-3320
-
(2010)
Eur J Immunol
, vol.40
, Issue.12
, pp. 3317-3320
-
-
Mantovani, A.1
-
43
-
-
81155123167
-
T-cell activation and maturation at tumor site associated with objective response to ipilimumab in metastatic melanoma
-
10.1200/JCO.2011.36.5957
-
Del Vecchio M, Mortarini R, Tragni G, Di Guardo L, Bersani I, Di Tolla G, Agustoni F, Colonna V, Weber JS, Anichini A (2011) T-cell activation and maturation at tumor site associated with objective response to ipilimumab in metastatic melanoma. J Clin Oncol 29(32):783-788
-
(2011)
J Clin Oncol
, vol.29
, Issue.32
, pp. 783-788
-
-
Del Vecchio, M.1
Mortarini, R.2
Tragni, G.3
Di Guardo, L.4
Bersani, I.5
Di Tolla, G.6
Agustoni, F.7
Colonna, V.8
Weber, J.S.9
Anichini, A.10
-
44
-
-
70350133511
-
IL4Ralpha + myeloid-derived suppressor cell expansion in cancer patients
-
1:CAS:528:DC%2BD1MXltlymt7Y%3D 19414811 10.4049/jimmunol.0803831
-
Mandruzzato S, Solito S, Falisi E, Francescato S, Chiarion-Sileni V, Mocellin S, Zanon A, Rossi CR, Nitti D, Bronte V, Zanovello P (2009) IL4Ralpha + myeloid-derived suppressor cell expansion in cancer patients. J Immunol 182(10):6562-6568
-
(2009)
J Immunol
, vol.182
, Issue.10
, pp. 6562-6568
-
-
Mandruzzato, S.1
Solito, S.2
Falisi, E.3
Francescato, S.4
Chiarion-Sileni, V.5
Mocellin, S.6
Zanon, A.7
Rossi, C.R.8
Nitti, D.9
Bronte, V.10
Zanovello, P.11
-
45
-
-
84863484555
-
Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypoproteinemia in patients with cancer
-
22614133
-
Ohki S, Shibata M, Gonda K, Machida T, Shimura T, Nakamura I, Ohtake T, Koyama Y, Suzuki S, Ohto H, Takenoshita S (2012) Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypoproteinemia in patients with cancer. Oncol Rep 28(2):453-458
-
(2012)
Oncol Rep
, vol.28
, Issue.2
, pp. 453-458
-
-
Ohki, S.1
Shibata, M.2
Gonda, K.3
Machida, T.4
Shimura, T.5
Nakamura, I.6
Ohtake, T.7
Koyama, Y.8
Suzuki, S.9
Ohto, H.10
Takenoshita, S.11
-
46
-
-
84873098095
-
Neoadjuvant ipilimumab in locally/regionally advanced melanoma: Clinical outcome and immune monitoring
-
Abstract 8553
-
Tarhini A (2012) Neoadjuvant ipilimumab in locally/regionally advanced melanoma: clinical outcome and immune monitoring. J Clin Oncol 30:Abstract 8553
-
(2012)
J Clin Oncol
, vol.30
-
-
Tarhini, A.1
-
47
-
-
84868240415
-
Differing patterns of circulating regulatory T cells and myeloid-derived suppressor cells in metastatic melanoma patients receiving anti-CTLA4 antibody and interferon-alpha or TLR-9 agonist and GM-CSF with peptide vaccination
-
1:CAS:528:DC%2BC38XhsFGqt7jI 3513773 23090079 10.1097/CJI. 0b013e318272569b
-
Tarhini AA, Butterfield LH, Shuai Y, Gooding WE, Kalinski P, Kirkwood JM (2012) Differing patterns of circulating regulatory T cells and myeloid-derived suppressor cells in metastatic melanoma patients receiving anti-CTLA4 antibody and interferon-alpha or TLR-9 agonist and GM-CSF with peptide vaccination. J Immunother 35(9):702-710
-
(2012)
J Immunother
, vol.35
, Issue.9
, pp. 702-710
-
-
Tarhini, A.A.1
Butterfield, L.H.2
Shuai, Y.3
Gooding, W.E.4
Kalinski, P.5
Kirkwood, J.M.6
-
48
-
-
0036122958
-
Expression of CTLA-4 by human monocytes
-
1:CAS:528:DC%2BD38XitFOjur4%3D 11841692 10.1046/j.0300-9475.2001.01019.x
-
Wang XB, Giscombe R, Yan Z, Heiden T, Xu D, Lefvert AK (2002) Expression of CTLA-4 by human monocytes. Scand J Immunol 55(1):53-60
-
(2002)
Scand J Immunol
, vol.55
, Issue.1
, pp. 53-60
-
-
Wang, X.B.1
Giscombe, R.2
Yan, Z.3
Heiden, T.4
Xu, D.5
Lefvert, A.K.6
-
49
-
-
77958553315
-
Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma
-
2939876 20856802 10.1371/journal.pone.0012711
-
Comin-Anduix B, Sazegar H, Chodon T, Matsunaga D, Jalil J, von Euw E, Escuin-Ordinas H, Balderas R, Chmielowski B, Gomez-Navarro J, Koya RC, Ribas A (2010) Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma. PLoS ONE 5(9):e12711
-
(2010)
PLoS ONE
, vol.5
, Issue.9
, pp. 12711
-
-
Comin-Anduix, B.1
Sazegar, H.2
Chodon, T.3
Matsunaga, D.4
Jalil, J.5
Von Euw, E.6
Escuin-Ordinas, H.7
Balderas, R.8
Chmielowski, B.9
Gomez-Navarro, J.10
Koya, R.C.11
Ribas, A.12
-
50
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
3401888 18446337 10.1007/s00262-008-0523-4
-
Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ (2008) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 58(1):49-59
-
(2008)
Cancer Immunol Immunother
, vol.58
, Issue.1
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
Garrett-Mayer, E.4
Cole, D.J.5
Montero, A.J.6
-
51
-
-
65249138393
-
Myeloid-derived suppressor cells: Linking inflammation and cancer
-
1:CAS:528:DC%2BD1MXjvFOjtrg%3D 2810498 19342621 10.4049/jimmunol.0802740
-
Ostrand-Rosenberg S, Sinha P (2009) Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 182(8):4499-4506
-
(2009)
J Immunol
, vol.182
, Issue.8
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
52
-
-
84862769116
-
An immune-active tumor microenvironment favors clinical response to ipilimumab
-
22146893 10.1007/s00262-011-1172-6
-
Ji RR, Chasalow SD, Wang L, Hamid O, Schmidt H, Cogswell J, Alaparthy S, Berman D, Jure-Kunkel M, Siemers NO, Jackson JR, Shahabi V (2011) An immune-active tumor microenvironment favors clinical response to ipilimumab. Cancer Immunol Immunother 61(7):1019-1031
-
(2011)
Cancer Immunol Immunother
, vol.61
, Issue.7
, pp. 1019-1031
-
-
Ji, R.R.1
Chasalow, S.D.2
Wang, L.3
Hamid, O.4
Schmidt, H.5
Cogswell, J.6
Alaparthy, S.7
Berman, D.8
Jure-Kunkel, M.9
Siemers, N.O.10
Jackson, J.R.11
Shahabi, V.12
-
53
-
-
84864662070
-
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
-
1:CAS:528:DC%2BC38XhtFWmsL%2FJ 22842478 10.1038/nm.2883
-
Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, Staehler M, Brugger W, Dietrich PY, Mendrzyk R, Hilf N, Schoor O, Fritsche J, Mahr A, Maurer D, Vass V, Trautwein C, Lewandrowski P, Flohr C, Pohla H, Stanczak JJ, Bronte V, Mandruzzato S, Biedermann T, Pawelec G, Derhovanessian E, Yamagishi H, Miki T, Hongo F, Takaha N, Hirakawa K, Tanaka H, Stevanovic S, Frisch J, Mayer-Mokler A, Kirner A, Rammensee HG, Reinhardt C, Singh-Jasuja H (2012) Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med 18(8):1254-1261
-
(2012)
Nat Med
, vol.18
, Issue.8
, pp. 1254-1261
-
-
Walter, S.1
Weinschenk, T.2
Stenzl, A.3
Zdrojowy, R.4
Pluzanska, A.5
Szczylik, C.6
Staehler, M.7
Brugger, W.8
Dietrich, P.Y.9
Mendrzyk, R.10
Hilf, N.11
Schoor, O.12
Fritsche, J.13
Mahr, A.14
Maurer, D.15
Vass, V.16
Trautwein, C.17
Lewandrowski, P.18
Flohr, C.19
Pohla, H.20
Stanczak, J.J.21
Bronte, V.22
Mandruzzato, S.23
Biedermann, T.24
Pawelec, G.25
Derhovanessian, E.26
Yamagishi, H.27
Miki, T.28
Hongo, F.29
Takaha, N.30
Hirakawa, K.31
Tanaka, H.32
Stevanovic, S.33
Frisch, J.34
Mayer-Mokler, A.35
Kirner, A.36
Rammensee, H.G.37
Reinhardt, C.38
Singh-Jasuja, H.39
more..
-
54
-
-
80054102628
-
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
-
1:CAS:528:DC%2BC3MXht1SitLvL 3176406 21644036 10.1007/s00262-011-1028-0
-
Gabitass RF, Annels NE, Stocken DD, Pandha HA, Middleton GW (2011) Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13. Cancer Immunol Immunother 60(10):1419-1430
-
(2011)
Cancer Immunol Immunother
, vol.60
, Issue.10
, pp. 1419-1430
-
-
Gabitass, R.F.1
Annels, N.E.2
Stocken, D.D.3
Pandha, H.A.4
Middleton, G.W.5
|