메뉴 건너뛰기




Volumn 121, Issue 6, 2011, Pages 2371-2382

CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 ANILINOADENOSINE; 5' NUCLEOTIDASE; ALPHA,BETA METHYLENEADENOSINE DIPHOSPHATE; CD73 INHIBITOR; ENZYME INHIBITOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD73; UNCLASSIFIED DRUG;

EID: 79957921286     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI45559     Document Type: Article
Times cited : (215)

References (56)
  • 1
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • DOI 10.1038/nrc1586
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer. 2005;5(4):263-274. (Pubitemid 40488632)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.4 , pp. 263-274
    • Zou, W.1
  • 2
    • 0002724633 scopus 로고    scopus 로고
    • Philadelphia, Pennsylvania, USA: Lippincott Williams & Wilkins
    • Schreiber H, ed. Tumor Immunology. Philadelphia, Pennsylvania, USA: Lippincott Williams & Wilkins; 2003:1557-1592.
    • (2003) Tumor Immunology , pp. 1557-1592
    • Schreiber, H.1
  • 3
    • 33947259319 scopus 로고    scopus 로고
    • Immunosuppressive strategies that are mediated by tumor cells
    • DOI 10.1146/annurev.immunol.25.022106.141609
    • Rabinovich GA, Gabrilovich D, Sotomayor EM. Immunosuppressive strategies that are mediated by tumor cells. Annu Rev Immunol. 2007;25:267-296. (Pubitemid 46697910)
    • (2007) Annual Review of Immunology , vol.25 , pp. 267-296
    • Rabinovich, G.A.1    Gabrilovich, D.2    Sotomayor, E.M.3
  • 5
    • 0030785819 scopus 로고    scopus 로고
    • The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine
    • Blay J, White TD, Hoskin DW. The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine. Cancer Res. 1997;57(13):2602-2605. (Pubitemid 27283766)
    • (1997) Cancer Research , vol.57 , Issue.13 , pp. 2602-2605
    • Blay, J.1    White, T.D.2    Hoskin, D.W.3
  • 6
    • 0033796779 scopus 로고    scopus 로고
    • Tumor-promoting functions of adenosine
    • Spychala J. Tumor-promoting functions of adenosine. Pharmacol Ther. 2000;87(2-3):161-173.
    • (2000) Pharmacol Ther , vol.87 , Issue.2-3 , pp. 161-173
    • Spychala, J.1
  • 7
    • 77957564570 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and adenosine in cancer
    • Stagg J, Smyth MJ. Extracellular adenosine triphosphate and adenosine in cancer. Oncogene. 2010; 29(39):5346-5358.
    • (2010) Oncogene , vol.29 , Issue.39 , pp. 5346-5358
    • Stagg, J.1    Smyth, M.J.2
  • 8
    • 40249106427 scopus 로고    scopus 로고
    • Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)
    • Hoskin DW, Mader JS, Furlong SJ, Conrad DM, Blay J. Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review). Int J Oncol. 2008;32(3):527-535. (Pubitemid 351330458)
    • (2008) International Journal of Oncology , vol.32 , Issue.3 , pp. 527-535
    • Hoskin, D.W.1    Mader, J.S.2    Furlong, S.J.3    Conrad, D.M.4    Blay, J.5
  • 9
    • 77955750932 scopus 로고    scopus 로고
    • CD73: A novel target for cancer immunotherapy
    • Zhang B. CD73: A novel target for cancer immunotherapy. Cancer Res. 2010;70(16):6407-6411.
    • (2010) Cancer Res , vol.70 , Issue.16 , pp. 6407-6411
    • Zhang, B.1
  • 10
    • 0031933227 scopus 로고    scopus 로고
    • Ecto-enzyme and signaling functions of lymphocyte CD73
    • Resta R, Yamashita Y, Thompson LF. Ecto-enzyme and signaling functions of lymphocyte CD73. Immunol Rev. 1998;161:95-109.
    • (1998) Immunol Rev , vol.161 , pp. 95-109
    • Resta, R.1    Yamashita, Y.2    Thompson, L.F.3
  • 12
    • 77950231071 scopus 로고    scopus 로고
    • CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumor-induced immune suppression
    • Jin D, et al. CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression. Cancer Res. 2010; 70(6):2245-2255.
    • (2010) Cancer Res , vol.70 , Issue.6 , pp. 2245-2255
    • Jin, D.1
  • 13
    • 75949112218 scopus 로고    scopus 로고
    • Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
    • Stagg J, et al. Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis. Proc Natl Acad Sci U S A. 2010;107(4):1547-1552.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.4 , pp. 1547-1552
    • Stagg, J.1
  • 15
    • 0027440443 scopus 로고
    • Lymphocyte-vascular adhesion protein-2 is a novel 70-kDa molecule involved in lymphocyte adhesion to vascular endothelium
    • Airas L, Salmi M, Jalkanen S. Lymphocyte-vascular adhesion protein-2 is a novel 70-kDa molecule involved in lymphocyte adhesion to vascular endothelium. J Immunol. 1993;151(8):4228-4238. (Pubitemid 23298756)
    • (1993) Journal of Immunology , vol.151 , Issue.8 , pp. 4228-4238
    • Airas, L.1    Salmi, M.2    Jalkanen, S.3
  • 17
    • 33750832563 scopus 로고    scopus 로고
    • T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine
    • Kobie JJ, Shah PR, Yang L, Rebhahn JA, Fowell DJ, Mosmann TR. T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. J Immunol. 2006; 177(10):6780-6786. (Pubitemid 44715042)
    • (2006) Journal of Immunology , vol.177 , Issue.10 , pp. 6780-6786
    • Kobie, J.J.1    Shah, P.R.2    Yang, L.3    Rebhahn, J.A.4    Fowell, D.J.5    Mosmann, T.R.6
  • 19
    • 41849103115 scopus 로고    scopus 로고
    • IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers
    • DOI 10.1172/JCI33522
    • Zhang B, Karrison T, Rowley DA, Schreiber H. IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers. J Clin Invest. 2008;118(4):1398-1404. (Pubitemid 351500433)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.4 , pp. 1398-1404
    • Zhang, B.1    Karrison, T.2    Rowley, D.A.3    Schreiber, H.4
  • 20
    • 44449146084 scopus 로고    scopus 로고
    • CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes
    • Takedachi M, et al. CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes. J Immunol. 2008;180(9):6288-6296.
    • (2008) J Immunol , vol.180 , Issue.9 , pp. 6288-6296
    • Takedachi, M.1
  • 21
    • 61849104046 scopus 로고    scopus 로고
    • CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice
    • Alam MS, et al. CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice. J Infect Dis. 2009;199(4):494-504.
    • (2009) J Infect Dis , vol.199 , Issue.4 , pp. 494-504
    • Alam, M.S.1
  • 22
    • 49649121241 scopus 로고    scopus 로고
    • Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma
    • Kline J, et al. Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma. Clin Cancer Res. 2008;14(10):3156-3167.
    • (2008) Clin Cancer Res , vol.14 , Issue.10 , pp. 3156-3167
    • Kline, J.1
  • 23
    • 36148939150 scopus 로고    scopus 로고
    • IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity
    • DOI 10.1182/blood-2007-06-094615
    • Litzinger MT, Fernando R, Curiel TJ, Grosenbach DW, Schlom J, Palena C. IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity. Blood. 2007;110(9):3192-3201. (Pubitemid 350106311)
    • (2007) Blood , vol.110 , Issue.9 , pp. 3192-3201
    • Litzinger, M.T.1    Fernando, R.2    Curiel, T.J.3    Grosenbach, D.W.4    Schlom, J.5    Palena, C.6
  • 24
  • 25
    • 0029817963 scopus 로고    scopus 로고
    • CD73 mediates adhesion of B cells to follicular dendritic cells
    • Airas L, Jalkanen S. CD73 mediates adhesion of B cells to follicular dendritic cells. Blood. 1996; 88(5):1755-1764. (Pubitemid 26307072)
    • (1996) Blood , vol.88 , Issue.5 , pp. 1755-1764
    • Airas, L.1    Jalkanen, S.2
  • 26
    • 52649138296 scopus 로고    scopus 로고
    • Adenosine receptors in regulation of dendritic cell differentiation and function
    • Novitskiy SV, et al. Adenosine receptors in regulation of dendritic cell differentiation and function. Blood. 2008;112(5):1822-1831.
    • (2008) Blood , vol.112 , Issue.5 , pp. 1822-1831
    • Novitskiy, S.V.1
  • 27
    • 65249184022 scopus 로고    scopus 로고
    • The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells
    • Wilson JM, et al. The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells. J Immunol. 2009;182(8):4616-4623.
    • (2009) J Immunol , vol.182 , Issue.8 , pp. 4616-4623
    • Wilson, J.M.1
  • 28
    • 77958153282 scopus 로고    scopus 로고
    • IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46
    • Eisenring M, vom Berg J, Kristiansen G, Saller E, Becher B. IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. Nat Immunol. 2010;11(11):1030-1038.
    • (2010) Nat Immunol , vol.11 , Issue.11 , pp. 1030-1038
    • Eisenring, M.1    Vom Berg, J.2    Kristiansen, G.3    Saller, E.4    Becher, B.5
  • 29
    • 25844523991 scopus 로고    scopus 로고
    • Cell-surface enzymes in control of leukocyte trafficking
    • DOI 10.1038/nri1705
    • Salmi M, Jalkanen S. Cell-surface enzymes in control of leukocyte trafficking. Nat Rev Immunol. 2005;5(10):760-771. (Pubitemid 41400850)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.10 , pp. 760-771
    • Salmi, M.1    Jalkanen, S.2
  • 30
    • 0028838712 scopus 로고
    • CD73 is involved in lymphocyte binding to the endothelium: Characterization of lymphocyte- Vascular adhesion protein 2 identifies it as CD73
    • Airas L, et al. CD73 is involved in lymphocyte binding to the endothelium: characterization of lymphocyte- vascular adhesion protein 2 identifies it as CD73. J Exp Med. 1995;182(5):1603-1608.
    • (1995) J Exp Med , vol.182 , Issue.5 , pp. 1603-1608
    • Airas, L.1
  • 31
    • 0034669958 scopus 로고    scopus 로고
    • CD73 engagement promotes lymphocyte binding to endothelial cells via a lymphocyte function-associated antigen-1-dependent mechanism
    • Airas L, Niemela J, Jalkanen S. CD73 engagement promotes lymphocyte binding to endothelial cells via a lymphocyte function-associated antigen-1-dependent mechanism. J Immunol. 2000;165(10):5411-5417.
    • (2000) J Immunol , vol.165 , Issue.10 , pp. 5411-5417
    • Airas, L.1    Niemela, J.2    Jalkanen, S.3
  • 33
    • 10244222236 scopus 로고    scopus 로고
    • Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: Coordination by extracellular nucleotide metabolism
    • DOI 10.1182/blood-2004-06-2066
    • Eltzschig HK, et al. Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood. 2004;104(13):3986-3992. (Pubitemid 39620148)
    • (2004) Blood , vol.104 , Issue.13 , pp. 3986-3992
    • Eltzschig, H.K.1    Thompson, L.F.2    Karhausen, J.3    Cotta, R.J.4    Ibla, J.C.5    Robson, S.C.6    Colgan, S.P.7
  • 34
    • 41349114840 scopus 로고    scopus 로고
    • A2B adenosine receptor dampens hypoxia-induced vascular leak
    • DOI 10.1182/blood-2007-10-117044
    • Eckle T, Faigle M, Grenz A, Laucher S, Thompson LF, Eltzschig HK. A2B adenosine receptor dampens hypoxia-induced vascular leak. Blood. 2008;111(4):2024-2035. (Pubitemid 351451513)
    • (2008) Blood , vol.111 , Issue.4 , pp. 2024-2035
    • Eckle, T.1    Faigle, M.2    Grenz, A.3    Laucher, S.4    Thompson, L.F.5    Eltzschig, H.K.6
  • 35
    • 48249097173 scopus 로고    scopus 로고
    • CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis
    • Mills JH, et al. CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2008;105(27):9325-9330.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.27 , pp. 9325-9330
    • Mills, J.H.1
  • 37
    • 74549136229 scopus 로고    scopus 로고
    • Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion
    • Chadjichristos CE, et al. Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion. Circulation. 2010;121(1):123-131.
    • (2010) Circulation , vol.121 , Issue.1 , pp. 123-131
    • Chadjichristos, C.E.1
  • 38
    • 58149379886 scopus 로고    scopus 로고
    • Ecto-5' nucleotidase (CD73)-mediated adenosine generation and signaling in murine cardiac allograft vasculopathy
    • Hasegawa T, Bouis D, Liao H, Visovatti SH, Pinsky DJ. Ecto-5' nucleotidase (CD73)-mediated adenosine generation and signaling in murine cardiac allograft vasculopathy. Circ Res. 2008;103(12):1410-1421.
    • (2008) Circ Res , vol.103 , Issue.12 , pp. 1410-1421
    • Hasegawa, T.1    Bouis, D.2    Liao, H.3    Visovatti, S.H.4    Pinsky, D.J.5
  • 39
    • 33646456788 scopus 로고    scopus 로고
    • CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation
    • Zernecke A, et al. CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation. Circulation. 2006;113(17):2120-2127.
    • (2006) Circulation , vol.113 , Issue.17 , pp. 2120-2127
    • Zernecke, A.1
  • 40
    • 0032547817 scopus 로고    scopus 로고
    • Neutrophil-derived 5'-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A(2B) receptor activation
    • DOI 10.1084/jem.188.8.1433
    • Lennon PF, Taylor CT, Stahl GL, Colgan SP. Neutrophil- derived 5'-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation. J Exp Med. 1998;188(8):1433-1443. (Pubitemid 28489580)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.8 , pp. 1433-1443
    • Lennon, P.F.1    Taylor, C.T.2    Stahl, G.L.3    Colgan, S.P.4
  • 41
    • 0024594707 scopus 로고
    • Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties
    • DOI 10.1002/jcp.1041390122
    • Stelzner TJ, Weil JV, O'Brien RF. Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties. J Cell Physiol. 1989;139(1):157-166. (Pubitemid 19120283)
    • (1989) Journal of Cellular Physiology , vol.139 , Issue.1 , pp. 157-166
    • Stelzner, T.J.1    Weil, J.V.2    O'Brien, R.F.3
  • 42
    • 0029559205 scopus 로고
    • Isolation and characterization of the promoter of the human 5'-nucleotidase (CD73)-encoding gene
    • Hansen KR, Resta R, Webb CF, Thompson LF. Isolation and characterization of the promoter of the human 5'-nucleotidase (CD73)-encoding gene. Gene. 1995;167(1-2):307-312.
    • (1995) Gene , vol.167 , Issue.1-2 , pp. 307-312
    • Hansen, K.R.1    Resta, R.2    Webb, C.F.3    Thompson, L.F.4
  • 43
    • 0034327277 scopus 로고    scopus 로고
    • Regulation of endothelial CD73 by adenosine: Paracrine pathway for enhanced endothelial barrier function
    • Narravula S, Lennon PF, Mueller BU, Colgan SP. Regulation of endothelial CD73 by adenosine: paracrine pathway for enhanced endothelial barrier function. J Immunol. 2000;165(9):5262-5268.
    • (2000) J Immunol , vol.165 , Issue.9 , pp. 5262-5268
    • Narravula, S.1    Lennon, P.F.2    Mueller, B.U.3    Colgan, S.P.4
  • 44
    • 0031047221 scopus 로고    scopus 로고
    • Differential regulation and function of CD73, a glycosyl- Phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells
    • DOI 10.1083/jcb.136.2.421
    • Airas L, Niemela J, Salmi M, Puurunen T, Smith DJ, Jalkanen S. Differential regulation and function of CD73, a glycosyl-phosphatidylinositol- linked 70-kD adhesion molecule, on lymphocytes and endothelial cells. J Cell Biol. 1997;136(2):421-431. (Pubitemid 27063091)
    • (1997) Journal of Cell Biology , vol.136 , Issue.2 , pp. 421-431
    • Airas, L.1    Niemela, J.2    Salmi, M.3    Puurunen, T.4    Smith, D.J.5    Jalkanen, S.6
  • 46
    • 39749108699 scopus 로고    scopus 로고
    • Foxp3+CD4+ T cell-mediated immunosuppression involves extracellular nucleotide catabolism
    • Bynoe MS, Viret C. Foxp3+CD4+ T cell-mediated immunosuppression involves extracellular nucleotide catabolism. Trends Immunol. 2008;29(3):99-102.
    • (2008) Trends Immunol , vol.29 , Issue.3 , pp. 99-102
    • Bynoe, M.S.1    Viret, C.2
  • 47
    • 77956896083 scopus 로고    scopus 로고
    • Much ado about adenosine: Adenosine synthesis and function in regulatory T cell biology
    • Ernst PB, Garrison JC, Thompson LF. Much ado about adenosine: adenosine synthesis and function in regulatory T cell biology. J Immunol. 2010;185(4):1993-1998.
    • (2010) J Immunol , vol.185 , Issue.4 , pp. 1993-1998
    • Ernst, P.B.1    Garrison, J.C.2    Thompson, L.F.3
  • 48
    • 77956134431 scopus 로고    scopus 로고
    • CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice
    • Sun X, et al. CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice. Gastroenterology. 2010;139(3):1030-1040.
    • (2010) Gastroenterology , vol.139 , Issue.3 , pp. 1030-1040
    • Sun, X.1
  • 49
    • 77954229218 scopus 로고    scopus 로고
    • Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine- Mediated T cell hyporesponsiveness
    • Hilchey SP, et al. Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine- mediated T cell hyporesponsiveness. J Immunol. 2009;183(10):6157-6166.
    • (2009) J Immunol , vol.183 , Issue.10 , pp. 6157-6166
    • Hilchey, S.P.1
  • 50
    • 70350231926 scopus 로고    scopus 로고
    • Increased ectonucleotidase expression and activity in regulatory T cells of patients with head and neck cancer
    • Mandapathil M, et al. Increased ectonucleotidase expression and activity in regulatory T cells of patients with head and neck cancer. Clin Cancer Res. 2009;15(20):6348-6357.
    • (2009) Clin Cancer Res , vol.15 , Issue.20 , pp. 6348-6357
    • Mandapathil, M.1
  • 51
    • 77951234655 scopus 로고    scopus 로고
    • Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells
    • Mandapathil M, et al. Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells. J Biol Chem. 2010;285(10):7176-7186.
    • (2010) J Biol Chem , vol.285 , Issue.10 , pp. 7176-7186
    • Mandapathil, M.1
  • 52
    • 69849107597 scopus 로고    scopus 로고
    • Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
    • Kryczek I, et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood. 2009;114(6):1141-1149.
    • (2009) Blood , vol.114 , Issue.6 , pp. 1141-1149
    • Kryczek, I.1
  • 53
    • 77950196277 scopus 로고    scopus 로고
    • T(H)17 cells in tumour immunity and immunotherapy
    • Zou W, Restifo NP. T(H)17 cells in tumour immunity and immunotherapy. Nat Rev Immunol. 2010;10(4):248-256.
    • (2010) Nat Rev Immunol , vol.10 , Issue.4 , pp. 248-256
    • Zou, W.1    Restifo, N.P.2
  • 54
    • 50949115838 scopus 로고    scopus 로고
    • Host A(2B) adenosine receptors promote carcinoma growth
    • Ryzhov S, et al. Host A(2B) adenosine receptors promote carcinoma growth. Neoplasia. 2008; 10(9):987-995.
    • (2008) Neoplasia , vol.10 , Issue.9 , pp. 987-995
    • Ryzhov, S.1
  • 55
    • 38049000452 scopus 로고    scopus 로고
    • Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
    • Buckanovich RJ, et al. Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy. Nat Med. 2008;14(1):28-36.
    • (2008) Nat Med , vol.14 , Issue.1 , pp. 28-36
    • Buckanovich, R.J.1
  • 56
    • 78049406865 scopus 로고    scopus 로고
    • B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses
    • Lin PY, et al. B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses. J Immunol. 2010;185(5):2747-2753.
    • (2010) J Immunol , vol.185 , Issue.5 , pp. 2747-2753
    • Lin, P.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.