Rapid and consistent evolution of colistin resistance in extensively drug-resistant pseudomonas aeruginosa during morbidostat culture

Antimicrobial Agents and Chemotherapy

Volumn 61, Issue 9, 2017, Pages

  Dößelmann, Bianca ^a,g   Willmann, Matthias ^b,e   Steglich, Matthias ^c   Bunk, Boyke ^c,d   Nübel, Ulrich ^c,d   Peter, Silke ^b,e   Neher, Richard A ^a,f  

^a MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c LEIBNIZ INSTITUTE DSMZ GERMAN COLLECTION OF MICROORGANISMS AND CELL CULTURES   (Germany)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^e German Center for Research in Infectious Disease (DZIF)   (Germany)

^f UNIVERSITY OF BASEL   (Switzerland)

^g UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Colistin resistance; Experimental evolution; Morbidostat; Pseudomonas aeruginosa

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; COLISTIN;

DRUG EFFECTS; GENETICS; HUMAN; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE; MUTATION; PROCEDURES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; COLISTIN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 85028393639     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00043-17     Document Type: Article

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