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Volumn 17, Issue 1, 2016, Pages

The properties of spontaneous mutations in the opportunistic pathogen Pseudomonas aeruginosa

Author keywords

Genomics; Mismatch repair; Mutation accumulation; Mutation bias

Indexed keywords

DOUBLE STRANDED DNA;

EID: 84955685330     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-2244-3     Document Type: Article
Times cited : (65)

References (62)
  • 1
    • 84904381004 scopus 로고    scopus 로고
    • Effects of new mutations on fitness: insights from models and data
    • Bataillon T, Bailey SF. Effects of new mutations on fitness: insights from models and data. Ann NY Acad Sci. 2014;1320:76-92.
    • (2014) Ann NY Acad Sci , vol.1320 , pp. 76-92
    • Bataillon, T.1    Bailey, S.F.2
  • 4
    • 84867339877 scopus 로고    scopus 로고
    • Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing
    • Lee H, Popodi E, Tang H, Foster PL. Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing. Proc Natl Acad Sci U S A. 2012;109:E2774-83.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E2774-E2783
    • Lee, H.1    Popodi, E.2    Tang, H.3    Foster, P.L.4
  • 6
    • 78349270511 scopus 로고    scopus 로고
    • Infection With Transmissible Strains of Pseudomonas aeruginosa and Clinical Outcomes in Adults With Cystic Fibrosis
    • Aaron SD, Vandemheen KL, Ramotar K, Giesbrecht-Lewis T, Tullis E, Freitag A, et al. Infection With Transmissible Strains of Pseudomonas aeruginosa and Clinical Outcomes in Adults With Cystic Fibrosis. JAMA-J Am Med Assoc. 2010;304:2145-53.
    • (2010) JAMA-J Am Med Assoc , vol.304 , pp. 2145-2153
    • Aaron, S.D.1    Vandemheen, K.L.2    Ramotar, K.3    Giesbrecht-Lewis, T.4    Tullis, E.5    Freitag, A.6
  • 7
    • 78751559949 scopus 로고    scopus 로고
    • Clinical Significance of Microbial Infection and Adaptation in Cystic Fibrosis
    • Hauser AR, Jain M, Bar-Meir M, McColley SA. Clinical Significance of Microbial Infection and Adaptation in Cystic Fibrosis. Clin Microbiol Rev. 2011;24:29-70.
    • (2011) Clin Microbiol Rev , vol.24 , pp. 29-70
    • Hauser, A.R.1    Jain, M.2    Bar-Meir, M.3    McColley, S.A.4
  • 8
    • 84869219279 scopus 로고    scopus 로고
    • Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective
    • Folkesson A, Jelsbak L, Yang L, Johansen HK, Ciofu O, Hoiby N, et al. Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective. Nat Rev Microbiol. 2012;10:841-51.
    • (2012) Nat Rev Microbiol , vol.10 , pp. 841-851
    • Folkesson, A.1    Jelsbak, L.2    Yang, L.3    Johansen, H.K.4    Ciofu, O.5    Hoiby, N.6
  • 9
    • 85028139131 scopus 로고    scopus 로고
    • Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis
    • Marvig RL, Sommer LM, Molin S, Johansen HK. Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis. Nat Genet. 2015;47:57-64.
    • (2015) Nat Genet , vol.47 , pp. 57-64
    • Marvig, R.L.1    Sommer, L.M.2    Molin, S.3    Johansen, H.K.4
  • 10
    • 77954729491 scopus 로고    scopus 로고
    • Mutators in cystic fibrosis chronic lung infection: Prevalence, mechanisms, and consequences for antimicrobial therapy
    • Oliver A. Mutators in cystic fibrosis chronic lung infection: Prevalence, mechanisms, and consequences for antimicrobial therapy. Int J Med Microbiol. 2010;300:563-72.
    • (2010) Int J Med Microbiol , vol.300 , pp. 563-572
    • Oliver, A.1
  • 12
    • 77954644239 scopus 로고    scopus 로고
    • Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance
    • Oliver A, Mena A. Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance. Clin Microbiol Infect. 2010;16:798-808.
    • (2010) Clin Microbiol Infect , vol.16 , pp. 798-808
    • Oliver, A.1    Mena, A.2
  • 13
    • 81255195875 scopus 로고    scopus 로고
    • Evolution and Adaptation in Pseudomonas aeruginosa Biofilms Driven by Mismatch Repair System-Deficient Mutators
    • Lujan AM, Macia MD, Yang L, Molin S, Oliver A, Smania AM. Evolution and Adaptation in Pseudomonas aeruginosa Biofilms Driven by Mismatch Repair System-Deficient Mutators. PLoS ONE. 2011;6, e27842.
    • (2011) PLoS ONE , vol.6
    • Lujan, A.M.1    Macia, M.D.2    Yang, L.3    Molin, S.4    Oliver, A.5    Smania, A.M.6
  • 14
    • 84858673034 scopus 로고    scopus 로고
    • Antibiotic pressure compensates the biological cost associated with Pseudomonas aeruginosa hypermutable phenotypes in vitro and in a murine model of chronic airways infection
    • Alcala-Franco B, Montanari S, Cigana C, Bertoni G, Oliver A, Bragonzi A. Antibiotic pressure compensates the biological cost associated with Pseudomonas aeruginosa hypermutable phenotypes in vitro and in a murine model of chronic airways infection. J Antimicrob Chemother. 2012;67:962-9.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 962-969
    • Alcala-Franco, B.1    Montanari, S.2    Cigana, C.3    Bertoni, G.4    Oliver, A.5    Bragonzi, A.6
  • 15
    • 84881513008 scopus 로고    scopus 로고
    • Clonal Dissemination, Emergence of Mutator Lineages and Antibiotic Resistance Evolution in Pseudomonas aeruginosa Cystic Fibrosis Chronic Lung Infection
    • Lopez-Causape C, Rojo-Molinero E, Mulet X, Cabot G, Moya B, Figuerola J, et al. Clonal Dissemination, Emergence of Mutator Lineages and Antibiotic Resistance Evolution in Pseudomonas aeruginosa Cystic Fibrosis Chronic Lung Infection. PLoS ONE. 2013;8, e71001.
    • (2013) PLoS ONE , vol.8
    • Lopez-Causape, C.1    Rojo-Molinero, E.2    Mulet, X.3    Cabot, G.4    Moya, B.5    Figuerola, J.6
  • 17
    • 84878486976 scopus 로고    scopus 로고
    • Strong Purifying Selection at Synonymous Sites in D. melanogaster
    • Lawrie DS, Messer PW, Hershberg R, Petrov DA. Strong Purifying Selection at Synonymous Sites in D. melanogaster. PLoS Genet. 2013;9:e1003527.
    • (2013) PLoS Genet , vol.9 , pp. e1003527
    • Lawrie, D.S.1    Messer, P.W.2    Hershberg, R.3    Petrov, D.A.4
  • 18
    • 84902313999 scopus 로고    scopus 로고
    • Adaptive synonymous mutations in an experimentally evolved Pseudomonas fluorescens population
    • Bailey SF, Hinz A, Kassen R. Adaptive synonymous mutations in an experimentally evolved Pseudomonas fluorescens population. Nat Commun. 2014;5:4076.
    • (2014) Nat Commun , vol.5 , pp. 4076
    • Bailey, S.F.1    Hinz, A.2    Kassen, R.3
  • 19
    • 56649099178 scopus 로고    scopus 로고
    • Whole-genome mutational biases in bacteria
    • Lind PA, Andersson DI. Whole-genome mutational biases in bacteria. Proc Natl Acad Sci U S A. 2008;105:17878-83.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 17878-17883
    • Lind, P.A.1    Andersson, D.I.2
  • 20
    • 84904261191 scopus 로고    scopus 로고
    • Fitness Is Strongly Influenced by Rare Mutations of Large Effect in a Microbial Mutation Accumulation Experiment
    • Heilbron K, Toll-Riera M, Kojadinovic M, MacLean RC. Fitness Is Strongly Influenced by Rare Mutations of Large Effect in a Microbial Mutation Accumulation Experiment. Genetics. 2014;197:981-90.
    • (2014) Genetics , vol.197 , pp. 981-990
    • Heilbron, K.1    Toll-Riera, M.2    Kojadinovic, M.3    MacLean, R.C.4
  • 21
    • 84891362153 scopus 로고    scopus 로고
    • Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa
    • Dettman JR, Rodrigue N, Aaron SD, Kassen R. Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2013;110:21065-70.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 21065-21070
    • Dettman, J.R.1    Rodrigue, N.2    Aaron, S.D.3    Kassen, R.4
  • 22
    • 0025886466 scopus 로고
    • A constant rate of spontaneous mutation in DNA-based microbes
    • Drake JW. A constant rate of spontaneous mutation in DNA-based microbes. Proc Natl Acad Sci U S A. 1991;88:7160-4.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 7160-7164
    • Drake, J.W.1
  • 23
    • 0026542473 scopus 로고
    • Slippage Synthesis of Simple Sequence DNA
    • Schlotterer C, Tautz D. Slippage Synthesis of Simple Sequence DNA. Nucleic Acids Res. 1992;20:211-5.
    • (1992) Nucleic Acids Res , vol.20 , pp. 211-215
    • Schlotterer, C.1    Tautz, D.2
  • 24
    • 84884679783 scopus 로고    scopus 로고
    • Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators
    • Marvig RL, Johansen HK, Molin S, Jelsbak L. Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators. PLoS Genet. 2013;9, e1003741.
    • (2013) PLoS Genet , vol.9
    • Marvig, R.L.1    Johansen, H.K.2    Molin, S.3    Jelsbak, L.4
  • 25
    • 78049445172 scopus 로고    scopus 로고
    • Evidence That Mutation Is Universally Biased towards AT in Bacteria
    • Hershberg R, Petrov DA. Evidence That Mutation Is Universally Biased towards AT in Bacteria. PLoS Genet. 2010;6, e1001115.
    • (2010) PLoS Genet , vol.6
    • Hershberg, R.1    Petrov, D.A.2
  • 26
    • 75749103383 scopus 로고    scopus 로고
    • Rate, molecular spectrum, and consequences of human mutation
    • Lynch M. Rate, molecular spectrum, and consequences of human mutation. Proc Natl Acad Sci U S A. 2010;107:961-8.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 961-968
    • Lynch, M.1
  • 27
    • 84867383562 scopus 로고    scopus 로고
    • The presence of the DNA repair genes mutM, mutY, mutL, and mutS is related to proteome size in bacterial genomes
    • Garcia-Gonzalez A, Rivera-Rivera RJ, Massey SE. The presence of the DNA repair genes mutM, mutY, mutL, and mutS is related to proteome size in bacterial genomes. Front Genet. 2012;3:3.
    • (2012) Front Genet , vol.3 , pp. 3
    • Garcia-Gonzalez, A.1    Rivera-Rivera, R.J.2    Massey, S.E.3
  • 28
    • 33748700552 scopus 로고    scopus 로고
    • Hypermutable bacteria isolated from humans - a critical analysis
    • Hall LMC, Henderson-Begg SK. Hypermutable bacteria isolated from humans - a critical analysis. Microbiology. 2006;152:2505-14.
    • (2006) Microbiology , vol.152 , pp. 2505-2514
    • Hall, L.M.C.1    Henderson-Begg, S.K.2
  • 29
    • 0029860724 scopus 로고    scopus 로고
    • High mutation frequencies among Escherichia coli and Salmonella pathogens
    • LeClerc JE, Li BG, Payne WL, Cebula TA. High mutation frequencies among Escherichia coli and Salmonella pathogens. Science. 1996;274:1208-11.
    • (1996) Science , vol.274 , pp. 1208-1211
    • LeClerc, J.E.1    Li, B.G.2    Payne, W.L.3    Cebula, T.A.4
  • 30
    • 0036134905 scopus 로고    scopus 로고
    • High frequency of mutator strains among human uropathogenic Escherichia coli isolates
    • Denamur E, Bonacorsi S, Giraud A, Duriez P, Hilali F, Amorin C, et al. High frequency of mutator strains among human uropathogenic Escherichia coli isolates. J Bacteriol. 2002;184:605-9.
    • (2002) J Bacteriol , vol.184 , pp. 605-609
    • Denamur, E.1    Bonacorsi, S.2    Giraud, A.3    Duriez, P.4    Hilali, F.5    Amorin, C.6
  • 31
    • 78049425463 scopus 로고    scopus 로고
    • Evidence of Selection upon Genomic GC-Content in Bacteria
    • Hildebrand F, Meyer A, Eyre-Walker A. Evidence of Selection upon Genomic GC-Content in Bacteria. PLoS Genet. 2010;6, e1001107.
    • (2010) PLoS Genet , vol.6
    • Hildebrand, F.1    Meyer, A.2    Eyre-Walker, A.3
  • 32
    • 84865973296 scopus 로고    scopus 로고
    • A selective force favoring increased G + C content in bacterial genes
    • Raghavan R, Kelkar YD, Ochman H. A selective force favoring increased G + C content in bacterial genes. Proc Natl Acad Sci U S A. 2012;109:14504-7.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 14504-14507
    • Raghavan, R.1    Kelkar, Y.D.2    Ochman, H.3
  • 33
    • 78049437494 scopus 로고    scopus 로고
    • Mutational Patterns Cannot Explain Genome Composition: Are There Any Neutral Sites in the Genomes of Bacteria?
    • Rocha EPC, Feil EJ. Mutational Patterns Cannot Explain Genome Composition: Are There Any Neutral Sites in the Genomes of Bacteria? PLoS Genet. 2010;6, e1001104.
    • (2010) PLoS Genet , vol.6
    • Rocha, E.P.C.1    Feil, E.J.2
  • 34
    • 0026701365 scopus 로고
    • The GO System Protects Organisms From the Mutagenic Effect of the Spontaneous Lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
    • Michaels ML, Miller JH. The GO System Protects Organisms From the Mutagenic Effect of the Spontaneous Lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). J Bacteriol. 1992;174:6321-5.
    • (1992) J Bacteriol , vol.174 , pp. 6321-6325
    • Michaels, M.L.1    Miller, J.H.2
  • 35
    • 0026592966 scopus 로고
    • 8-hydroxyguanine, An Abundant Form of Oxidative Dna Damage, Causes G- > T and A- > C Substitutions
    • Cheng KC, Cahill DS, Kasai H, Nishimura S, Loeb LA. 8-hydroxyguanine, An Abundant Form of Oxidative Dna Damage, Causes G- > T and A- > C Substitutions. J Biol Chem. 1992;267:166-72.
    • (1992) J Biol Chem , vol.267 , pp. 166-172
    • Cheng, K.C.1    Cahill, D.S.2    Kasai, H.3    Nishimura, S.4    Loeb, L.A.5
  • 36
    • 77956190600 scopus 로고    scopus 로고
    • DNA methylation and mutator genes in Escherichia coli K-12
    • Marinus MG. DNA methylation and mutator genes in Escherichia coli K-12. Mutat Res. 2010;705:71-6.
    • (2010) Mutat Res , vol.705 , pp. 71-76
    • Marinus, M.G.1
  • 37
    • 32644434270 scopus 로고    scopus 로고
    • Base-stacking and base-pairing contributions into thermal stability of the DNA double helix
    • Yakovchuk P, Protozanova E, Frank-Kamenetskii MD. Base-stacking and base-pairing contributions into thermal stability of the DNA double helix. Nucleic Acids Res. 2006;34:564-74.
    • (2006) Nucleic Acids Res , vol.34 , pp. 564-574
    • Yakovchuk, P.1    Protozanova, E.2    Frank-Kamenetskii, M.D.3
  • 38
    • 0025344222 scopus 로고
    • A Sensitive Genetic Assay For the Detection of Cytosine Deamination: Determination of Rate Constants and the Activation Energy
    • Frederico LA, Kunkel TA, Shaw BR. A Sensitive Genetic Assay For the Detection of Cytosine Deamination: Determination of Rate Constants and the Activation Energy. Biochemistry. 1990;29:2532-7.
    • (1990) Biochemistry , vol.29 , pp. 2532-2537
    • Frederico, L.A.1    Kunkel, T.A.2    Shaw, B.R.3
  • 39
    • 84866930664 scopus 로고    scopus 로고
    • DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair
    • Fijalkowska IJ, Schaaper RM, Jonczyk P. DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair. FEMS Microbiol Rev. 2012;36:1105-21.
    • (2012) FEMS Microbiol Rev , vol.36 , pp. 1105-1121
    • Fijalkowska, I.J.1    Schaaper, R.M.2    Jonczyk, P.3
  • 40
    • 0019198357 scopus 로고
    • Mutagenic Deamination of Cytosine Residues In DNA
    • Duncan BK, Miller JH. Mutagenic Deamination of Cytosine Residues In DNA. Nature. 1980;287:560-1.
    • (1980) Nature , vol.287 , pp. 560-561
    • Duncan, B.K.1    Miller, J.H.2
  • 41
    • 3142679507 scopus 로고    scopus 로고
    • The replication-related organization of bacterial genomes
    • Rocha EPC. The replication-related organization of bacterial genomes. Microbiology. 2004;150:1609-27.
    • (2004) Microbiology , vol.150 , pp. 1609-1627
    • Rocha, E.P.C.1
  • 42
    • 0024966756 scopus 로고
    • Chromosomal Location and Evolutionary Rate Variation In Enterobacterial Genes
    • Sharp PM, Shields DC, Wolfe KH, Li WH. Chromosomal Location and Evolutionary Rate Variation In Enterobacterial Genes. Science. 1989;246:808-10.
    • (1989) Science , vol.246 , pp. 808-810
    • Sharp, P.M.1    Shields, D.C.2    Wolfe, K.H.3    Li, W.H.4
  • 43
    • 0036667696 scopus 로고    scopus 로고
    • Gene location and bacterial sequence divergence
    • Mira A, Ochman H. Gene location and bacterial sequence divergence. Mol Biol Evol. 2002;19:1350-8.
    • (2002) Mol Biol Evol , vol.19 , pp. 1350-1358
    • Mira, A.1    Ochman, H.2
  • 44
    • 79952200926 scopus 로고    scopus 로고
    • Evolutionary Rates and Gene Dispensability Associate with Replication Timing in the Archaeon Sulfolobus islandicus
    • Flynn KM, Vohr SH, Hatcher PJ, Cooper VS. Evolutionary Rates and Gene Dispensability Associate with Replication Timing in the Archaeon Sulfolobus islandicus. Genome Biol Evol. 2010;2:859-69.
    • (2010) Genome Biol Evol , vol.2 , pp. 859-869
    • Flynn, K.M.1    Vohr, S.H.2    Hatcher, P.J.3    Cooper, V.S.4
  • 46
    • 77955842436 scopus 로고    scopus 로고
    • Fisher's model and the genomics of adaptation: restricted pleiotropy, heterogenous mutation, and parallel evolution
    • Chevin L-M, Martin G, Lenormand T. Fisher's model and the genomics of adaptation: restricted pleiotropy, heterogenous mutation, and parallel evolution. Evolution. 2010;64:3213-31.
    • (2010) Evolution , vol.64 , pp. 3213-3231
    • Chevin, L.-M.1    Martin, G.2    Lenormand, T.3
  • 47
    • 0034685940 scopus 로고    scopus 로고
    • High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection
    • Oliver A, Canton R, Campo P, Baquero F, Blazquez J. High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. Science. 2000;288:1251-3.
    • (2000) Science , vol.288 , pp. 1251-1253
    • Oliver, A.1    Canton, R.2    Campo, P.3    Baquero, F.4    Blazquez, J.5
  • 48
    • 0037864230 scopus 로고    scopus 로고
    • High rate of macrolide resistance in Staphylococcus aureus strains from patients with cystic fibrosis reveals high proportions of hypermutable strains
    • Prunier AL, Malbruny B, Laurans M, Brouard J, Duhamel JF, Leclercq R. High rate of macrolide resistance in Staphylococcus aureus strains from patients with cystic fibrosis reveals high proportions of hypermutable strains. J Infect Dis. 2003;187:1709-16.
    • (2003) J Infect Dis , vol.187 , pp. 1709-1716
    • Prunier, A.L.1    Malbruny, B.2    Laurans, M.3    Brouard, J.4    Duhamel, J.F.5    Leclercq, R.6
  • 49
    • 15044340977 scopus 로고    scopus 로고
    • Dynamics of long-term colonization of respiratory tract by Haemophilus influenzae in cystic fibrosis patients shows a marked increase in hypermutable strains
    • Roman F, Canton R, Perez-Vazquez M, Baquero F, Campos J. Dynamics of long-term colonization of respiratory tract by Haemophilus influenzae in cystic fibrosis patients shows a marked increase in hypermutable strains. J Clin Microbiol. 2004;42:1450-9.
    • (2004) J Clin Microbiol , vol.42 , pp. 1450-1459
    • Roman, F.1    Canton, R.2    Perez-Vazquez, M.3    Baquero, F.4    Campos, J.5
  • 50
    • 19544386997 scopus 로고    scopus 로고
    • Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammation
    • Ciofu O, Riis B, Pressler T, Poulsen HE, Hoiby N. Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammation. Antimicrob Agents Chemother. 2005;49:2276-82.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2276-2282
    • Ciofu, O.1    Riis, B.2    Pressler, T.3    Poulsen, H.E.4    Hoiby, N.5
  • 51
    • 67049096137 scopus 로고    scopus 로고
    • Antibiotic Resistance in Pseudomonas aeruginosa Strains with Increased Mutation Frequency Due to Inactivation of the DNA Oxidative Repair System
    • Mandsberg LF, Ciofu O, Kirkby N, Christiansen LE, Poulsen HE, Hoiby N. Antibiotic Resistance in Pseudomonas aeruginosa Strains with Increased Mutation Frequency Due to Inactivation of the DNA Oxidative Repair System. Antimicrob Agents Chemother. 2009;53:2483-91.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2483-2491
    • Mandsberg, L.F.1    Ciofu, O.2    Kirkby, N.3    Christiansen, L.E.4    Poulsen, H.E.5    Hoiby, N.6
  • 52
    • 77955615902 scopus 로고    scopus 로고
    • Hypermutability and Compensatory Adaptation in Antibiotic-Resistant Bacteria
    • Perron GG, Hall AR, Buckling A. Hypermutability and Compensatory Adaptation in Antibiotic-Resistant Bacteria. Am Nat. 2010;176:303-11.
    • (2010) Am Nat , vol.176 , pp. 303-311
    • Perron, G.G.1    Hall, A.R.2    Buckling, A.3
  • 53
    • 84878438599 scopus 로고    scopus 로고
    • A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria
    • Torres-Barcelo C, Cabot G, Oliver A, Buckling A, MacLean RC. A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria. Proc R Soc B. 2013;280:20130007.
    • (2013) Proc R Soc B , vol.280 , pp. 20130007
    • Torres-Barcelo, C.1    Cabot, G.2    Oliver, A.3    Buckling, A.4    MacLean, R.C.5
  • 54
    • 84873490474 scopus 로고    scopus 로고
    • Mutational Spectrum Drives the Rise of Mutator Bacteria
    • Couce A, Guelfo JR, Blazquez J. Mutational Spectrum Drives the Rise of Mutator Bacteria. PLoS Genet. 2013;9, e1003167.
    • (2013) PLoS Genet , vol.9
    • Couce, A.1    Guelfo, J.R.2    Blazquez, J.3
  • 56
    • 79952222757 scopus 로고    scopus 로고
    • Positive Signature-Tagged Mutagenesis in Pseudomonas aeruginosa: Tracking Patho-Adaptive Mutations Promoting Airways Chronic Infection
    • Bianconi I, Milani A, Cigana C, Paroni M, Levesque RC, Bertoni G, et al. Positive Signature-Tagged Mutagenesis in Pseudomonas aeruginosa: Tracking Patho-Adaptive Mutations Promoting Airways Chronic Infection. PLoS Pathog. 2011;7, e1001270.
    • (2011) PLoS Pathog , vol.7
    • Bianconi, I.1    Milani, A.2    Cigana, C.3    Paroni, M.4    Levesque, R.C.5    Bertoni, G.6
  • 57
    • 0028065674 scopus 로고
    • Adaptive Evolution of Highly Mutable Loci In Pathogenic Bacteria
    • Moxon ER, Rainey PB, Nowak MA, Lenski RE. Adaptive Evolution of Highly Mutable Loci In Pathogenic Bacteria. Curr Biol. 1994;4:24-33.
    • (1994) Curr Biol , vol.4 , pp. 24-33
    • Moxon, E.R.1    Rainey, P.B.2    Nowak, M.A.3    Lenski, R.E.4
  • 58
    • 84866893020 scopus 로고    scopus 로고
    • Genomics of Adaptation during Experimental Evolution of the Opportunistic Pathogen Pseudomonas aeruginosa
    • Wong A, Rodrigue N, Kassen R. Genomics of Adaptation during Experimental Evolution of the Opportunistic Pathogen Pseudomonas aeruginosa. PLoS Genet. 2012;8, e1002928.
    • (2012) PLoS Genet , vol.8
    • Wong, A.1    Rodrigue, N.2    Kassen, R.3
  • 59
    • 84860663163 scopus 로고    scopus 로고
    • Evolutionary insight from whole-genome sequencing of experimentally evolved microbes
    • Dettman JR, Rodrigue N, Melnyk AH, Wong A, Bailey SF, Kassen R. Evolutionary insight from whole-genome sequencing of experimentally evolved microbes. Mol Ecol. 2012;21:2058-77.
    • (2012) Mol Ecol , vol.21 , pp. 2058-2077
    • Dettman, J.R.1    Rodrigue, N.2    Melnyk, A.H.3    Wong, A.4    Bailey, S.F.5    Kassen, R.6
  • 62
    • 84896523433 scopus 로고    scopus 로고
    • Mutation Rates, Spectra, and Genome-Wide Distribution of Spontaneous Mutations in Mismatch Repair Deficient Yeast
    • Lang GI, Parsons L, Gammie AE. Mutation Rates, Spectra, and Genome-Wide Distribution of Spontaneous Mutations in Mismatch Repair Deficient Yeast. G3-Genes Genom Genet. 2013;3:1453-65.
    • (2013) G3-Genes Genom Genet , vol.3 , pp. 1453-1465
    • Lang, G.I.1    Parsons, L.2    Gammie, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.