메뉴 건너뛰기




Volumn 186, Issue 2, 2004, Pages 575-579

PmrAB, a Two-Component Regulatory System of Pseudomonas aeruginosa that Modulates Resistance to Cationic Antimicrobial Peptides and Addition of Aminoarabinose to Lipid A

Author keywords

[No Author keywords available]

Indexed keywords

AMINOARABINOSE; ARABINOSE; BACTERIAL PROTEIN; CATIONIC ANTIMICROBIAL PEPTIDE; LIPID A; PEPTIDE DERIVATIVE; POLYMYXIN; PROTEIN PMRAB; UNCLASSIFIED DRUG;

EID: 0346655236     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.186.2.575-579.2004     Document Type: Article
Times cited : (323)

References (41)
  • 2
    • 0026647630 scopus 로고
    • Characterization of Escherichia coli glnL mutations affecting nitrogen regulation
    • Atkinson, M. R., and A. J. Ninfa. 1992. Characterization of Escherichia coli glnL mutations affecting nitrogen regulation. J. Bacteriol. 174:4538-4548.
    • (1992) J. Bacteriol. , vol.174 , pp. 4538-4548
    • Atkinson, M.R.1    Ninfa, A.J.2
  • 4
    • 0032169557 scopus 로고    scopus 로고
    • Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung
    • Bals, R., X. Wang, Z. Wu, T. Freeman, V. Bafna, M. Zasloff, and J. M. Wilson. 1998. Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J. Clin. Investig. 102:874-880.
    • (1998) J. Clin. Investig. , vol.102 , pp. 874-880
    • Bals, R.1    Wang, X.2    Wu, Z.3    Freeman, T.4    Bafna, V.5    Zasloff, M.6    Wilson, J.M.7
  • 5
    • 0032482980 scopus 로고    scopus 로고
    • The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface
    • Bals, R., X. Wang, M. Zasloff, and J. M. Wilson. 1998. The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc. Natl. Acad. Sci. USA 95:9541-9546.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9541-9546
    • Bals, R.1    Wang, X.2    Zasloff, M.3    Wilson, J.M.4
  • 6
    • 0025606271 scopus 로고
    • Structural studies of lipid A from Pseudomonas aeruginosa PAO1: Occurrence of 4-amino-4-deoxyarabinose
    • Bhat, R., A. Marx, C. Galanos, and R. S. Conrad. 1990. Structural studies of lipid A from Pseudomonas aeruginosa PAO1: occurrence of 4-amino-4-deoxyarabinose. J. Bacteriol. 172:6631-6636.
    • (1990) J. Bacteriol. , vol.172 , pp. 6631-6636
    • Bhat, R.1    Marx, A.2    Galanos, C.3    Conrad, R.S.4
  • 7
    • 0014643866 scopus 로고
    • Role of divalent cations in the action of polymyxin B and EDTA on Pseudomonas aeruginosa
    • Brown, M. R., and J. Melling. 1969. Role of divalent cations in the action of polymyxin B and EDTA on Pseudomonas aeruginosa. J. Gen. Microbiol. 59:263-274.
    • (1969) J. Gen. Microbiol. , vol.59 , pp. 263-274
    • Brown, M.R.1    Melling, J.2
  • 9
    • 0024459568 scopus 로고
    • Fatty acid alterations and polymyxin B binding by lipopolysaccharides from Pseudomonas aeruginosa adapted to polymyxin B resistance
    • Conrad, R. S., and C. Galanos. 1989. Fatty acid alterations and polymyxin B binding by lipopolysaccharides from Pseudomonas aeruginosa adapted to polymyxin B resistance. Antimicrob. Agents Chemother. 33:1724-1728.
    • (1989) Antimicrob. Agents Chemother. , vol.33 , pp. 1724-1728
    • Conrad, R.S.1    Galanos, C.2
  • 10
    • 0033761572 scopus 로고    scopus 로고
    • Safety and tolerability of bolus intravenous colistin in acute respiratory exacerbations in adults with cystic fibrosis
    • Conway, S. P., C. Etherington, J. Munday, M. H. Goldman, J. J. Strong, and M. Wootton. 2000. Safety and tolerability of bolus intravenous colistin in acute respiratory exacerbations in adults with cystic fibrosis. Ann. Pharmacother. 34:1238-1242.
    • (2000) Ann. Pharmacother. , vol.34 , pp. 1238-1242
    • Conway, S.P.1    Etherington, C.2    Munday, J.3    Goldman, M.H.4    Strong, J.J.5    Wootton, M.6
  • 12
    • 0036785981 scopus 로고    scopus 로고
    • Transmission of colistin-resistant Pseudomonas aeruginosa between patients attending a pediatric cystic fibrosis center
    • Denton, M., K. Kerr, L. Mooney, V. Keer, A. Rajgopal, K. Brownlee, P. Arundel, and S. Conway. 2002. Transmission of colistin-resistant Pseudomonas aeruginosa between patients attending a pediatric cystic fibrosis center. Pediatr. Pulmonol. 34:257-261.
    • (2002) Pediatr. Pulmonol. , vol.34 , pp. 257-261
    • Denton, M.1    Kerr, K.2    Mooney, L.3    Keer, V.4    Rajgopal, A.5    Brownlee, K.6    Arundel, P.7    Conway, S.8
  • 13
    • 0033584935 scopus 로고    scopus 로고
    • Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa
    • Ernst, R. K., E. C. Yi, L. Guo, K. B. Lim, J. L. Burns, M. Hackett, and S. I. Miller. 1999. Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa. Science 286:1561-1565.
    • (1999) Science , vol.286 , pp. 1561-1565
    • Ernst, R.K.1    Yi, E.C.2    Guo, L.3    Lim, K.B.4    Burns, J.L.5    Hackett, M.6    Miller, S.I.7
  • 14
    • 0032828524 scopus 로고    scopus 로고
    • Changing epidemiology of Pseudomonas aeruginosa infection in Danish cystic fibrosis patients (1974-1995)
    • Frederiksen, B., C. Koch, and N. Hoiby. 1999. Changing epidemiology of Pseudomonas aeruginosa infection in Danish cystic fibrosis patients (1974-1995). Pediatr. Pulmonol. 28:159-166.
    • (1999) Pediatr. Pulmonol. , vol.28 , pp. 159-166
    • Frederiksen, B.1    Koch, C.2    Hoiby, N.3
  • 15
    • 0022870839 scopus 로고
    • Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector
    • Furste, J. P., W. Pansegrau, R. Frank, H. Blocker, P. Scholz, M. Bagdasarian, and E. Lanka. 1986. Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene 48:119-131.
    • (1986) Gene , vol.48 , pp. 119-131
    • Furste, J.P.1    Pansegrau, W.2    Frank, R.3    Blocker, H.4    Scholz, P.5    Bagdasarian, M.6    Lanka, E.7
  • 16
    • 0017282737 scopus 로고
    • Ultrastructural study of polymyxin-resistant isolates of Pseudomonas aeruginosa
    • Gilleland, U. E., Jr., and R. G. E. Murray. 1976. Ultrastructural study of polymyxin-resistant isolates of Pseudomonas aeruginosa. J. Bacteriol. 125:267-281.
    • (1976) J. Bacteriol. , vol.125 , pp. 267-281
    • Gilleland Jr., U.E.1    Murray, R.G.E.2
  • 17
    • 0031909562 scopus 로고    scopus 로고
    • PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance
    • Gunn, J. S., K. B. Lim, J. Krueger, K. Kim, L. Guo, M. Hackett, and S. I. Miller, 1998. PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance. Mol. Microbiol. 27:1171-1182.
    • (1998) Mol. Microbiol. , vol.27 , pp. 1171-1182
    • Gunn, J.S.1    Lim, K.B.2    Krueger, J.3    Kim, K.4    Guo, L.5    Hackett, M.6    Miller, S.I.7
  • 18
    • 0029809576 scopus 로고    scopus 로고
    • PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance
    • Gunn, J. S., and S. I. Miller. 1996. PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance. J. Bacteriol. 178:6857-6864.
    • (1996) J. Bacteriol. , vol.178 , pp. 6857-6864
    • Gunn, J.S.1    Miller, S.I.2
  • 19
    • 0033794504 scopus 로고    scopus 로고
    • Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar Typhimurium
    • Gunn, J. S., S. S. Ryan, J. C. Van Velkinburgh, R. K. Ernst, and S. I. Miller. 2000. Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar Typhimurium. Infect. Immun. 68:6139-6146.
    • (2000) Infect. Immun. , vol.68 , pp. 6139-6146
    • Gunn, J.S.1    Ryan, S.S.2    Van Velkinburgh, J.C.3    Ernst, R.K.4    Miller, S.I.5
  • 20
    • 0019783923 scopus 로고
    • Ethylenediaminetetraacetate-extractable protein-lipopolysaccharide complex of Pseudomonas aeruginosa: Characterization of protein components
    • Hedstrom, R. C., R. K. Schockley, and R. G. Eagon. 1981. Ethylenediaminetetraacetate-extractable protein-lipopolysaccharide complex of Pseudomonas aeruginosa: characterization of protein components. J. Bacteriol. 148:995-997.
    • (1981) J. Bacteriol. , vol.148 , pp. 995-997
    • Hedstrom, R.C.1    Schockley, R.K.2    Eagon, R.G.3
  • 21
    • 0019394722 scopus 로고
    • 31P nuclear magnetic resonance spectroscopy of lipopolysaccharides from Pseudomonas aeruginosa
    • Horton, D., and D. A. Riley. 1981. 31P nuclear magnetic resonance spectroscopy of lipopolysaccharides from Pseudomonas aeruginosa. Biochim. Biophys. Acta 640:727-733.
    • (1981) Biochim. Biophys. Acta , vol.640 , pp. 727-733
    • Horton, D.1    Riley, D.A.2
  • 22
    • 0027051612 scopus 로고
    • Characterization of lipid A from Pseudomonas aeruginosa O-antigenic B band lipopolysaccharide by 1D and 2D NMR and mass spectral analysis
    • Karunaratne, D. N., J. C. Richards, and R. E. W. Hancock. 1992. Characterization of lipid A from Pseudomonas aeruginosa O-antigenic B band lipopolysaccharide by 1D and 2D NMR and mass spectral analysis. Arch. Biochem. Biophys. 299:368-376.
    • (1992) Arch. Biochem. Biophys. , vol.299 , pp. 368-376
    • Karunaratne, D.N.1    Richards, J.C.2    Hancock, R.E.W.3
  • 23
    • 0016634343 scopus 로고
    • Prevention of gram-negative bacillary pneumonia using polymyxin aerosol as prophylaxis. II. Effect on the incidence of pneumonia in seriously ill patients
    • Klick, J. M., G. C. du Moulin, J. Hedley-Whyte, D. Teres, L. S. Bushnell, and D. S. Feingold. 1975. Prevention of gram-negative bacillary pneumonia using polymyxin aerosol as prophylaxis. II. Effect on the incidence of pneumonia in seriously ill patients. J. Clin. Investig. 55:514-519.
    • (1975) J. Clin. Investig. , vol.55 , pp. 514-519
    • Klick, J.M.1    Du Moulin, G.C.2    Hedley-Whyte, J.3    Teres, D.4    Bushnell, L.S.5    Feingold, D.S.6
  • 24
    • 0342424729 scopus 로고    scopus 로고
    • A small protein that mediates the activation of a two-component system by another two-component system
    • Kox, L. F., M. M. Wosten, and E. A. Groisman. 2000. A small protein that mediates the activation of a two-component system by another two-component system. EMBO J. 19:1861-1872.
    • (2000) EMBO J. , vol.19 , pp. 1861-1872
    • Kox, L.F.1    Wosten, M.M.2    Groisman, E.A.3
  • 25
    • 0024391711 scopus 로고
    • Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity
    • Lehrer, R. I., A. Barton, K. A. Daher, S. S. Harwig, T. Ganz, and M. E. Selsted. 1989. Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J. Clin. Investig. 84:553-561.
    • (1989) J. Clin. Investig. , vol.84 , pp. 553-561
    • Lehrer, R.I.1    Barton, A.2    Daher, K.A.3    Harwig, S.S.4    Ganz, T.5    Selsted, M.E.6
  • 26
    • 0035118424 scopus 로고    scopus 로고
    • In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis
    • Li, J., J. Turnidge, R. Milne, R. L. Nation, and K. Coulthard. 2001. In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Antimicrob. Agents Chemother. 45:781-785.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 781-785
    • Li, J.1    Turnidge, J.2    Milne, R.3    Nation, R.L.4    Coulthard, K.5
  • 27
    • 0032850479 scopus 로고    scopus 로고
    • PhoP-PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer-membrane protein OprH and polymyxin B resistance
    • Macfarlane, E. L., A. Kwasnicka, M. M. Ochs, and R. E. Hancock. 1999. PhoP-PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer-membrane protein OprH and polymyxin B resistance. Mol. Microbiol. 34:305-316.
    • (1999) Mol. Microbiol. , vol.34 , pp. 305-316
    • Macfarlane, E.L.1    Kwasnicka, A.2    Ochs, M.M.3    Hancock, R.E.4
  • 28
    • 0141484326 scopus 로고    scopus 로고
    • Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa
    • McPhee, J. B., S. Lewenza, and R. E. Hancock. 2003. Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa. Mol. Microbiol. 50:205-217.
    • (2003) Mol. Microbiol. , vol.50 , pp. 205-217
    • McPhee, J.B.1    Lewenza, S.2    Hancock, R.E.3
  • 29
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov, R. 2001. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1:135-145.
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 30
    • 0021122872 scopus 로고
    • Evidence for two distinct mechanisms of resistance to polymyxin B in Pseudomonas aeruginosa
    • Moore, R. A., L. Chan, and R. E. W. Hancock. 1984. Evidence for two distinct mechanisms of resistance to polymyxin B in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 26:539-545.
    • (1984) Antimicrob. Agents Chemother. , vol.26 , pp. 539-545
    • Moore, R.A.1    Chan, L.2    Hancock, R.E.W.3
  • 31
    • 0035873909 scopus 로고    scopus 로고
    • Design of Gram-negative selective antimicrobial peptides
    • Muhle, S. A., and J. P. Tam. 2001. Design of Gram-negative selective antimicrobial peptides. Biochemistry 40:5777-5785.
    • (2001) Biochemistry , vol.40 , pp. 5777-5785
    • Muhle, S.A.1    Tam, J.P.2
  • 32
    • 0019312991 scopus 로고
    • Outer membrane protein H1 of Pseudomonas aeruginosa: Involvement in adaptive and mutational resistance to ethylenediaminetetraacetate, polymyxin B, and gentamicin
    • Nicas, T. I., and R. E. W. Hancock. 1980. Outer membrane protein H1 of Pseudomonas aeruginosa: involvement in adaptive and mutational resistance to ethylenediaminetetraacetate, polymyxin B, and gentamicin. J. Bacteriol. 143:872-878.
    • (1980) J. Bacteriol. , vol.143 , pp. 872-878
    • Nicas, T.I.1    Hancock, R.E.W.2
  • 33
    • 0028364818 scopus 로고
    • Isolation and characterization of a gene, pmrD, from Salmonella typhimurium that confers resistance to polymyxin when expressed in multiple copies
    • Roland, K. L., C. R. Esther, and J. K. Spitznagel, 1994. Isolation and characterization of a gene, pmrD, from Salmonella typhimurium that confers resistance to polymyxin when expressed in multiple copies. J. Bacteriol. 176:3589-3597.
    • (1994) J. Bacteriol. , vol.176 , pp. 3589-3597
    • Roland, K.L.1    Esther, C.R.2    Spitznagel, J.K.3
  • 34
    • 0027201144 scopus 로고
    • Spontaneous pmrA mutants of Salmonella typhimurium LT2 define a new two-component regulatory system with a possible role in virulence
    • Roland, K. L., L. E. Martin, C. R. Esther, and J. K. Spitznagel. 1993. Spontaneous pmrA mutants of Salmonella typhimurium LT2 define a new two-component regulatory system with a possible role in virulence. J. Bacteriol. 175:4154-4164.
    • (1993) J. Bacteriol. , vol.175 , pp. 4154-4164
    • Roland, K.L.1    Martin, L.E.2    Esther, C.R.3    Spitznagel, J.K.4
  • 35
    • 0036030617 scopus 로고    scopus 로고
    • Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37
    • Schmidtchen, A., I. M. Frick, E. Andersson, H. Tapper, and L. Bjorck. 2002. Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37. Mol. Microbiol. 46:157-168.
    • (2002) Mol. Microbiol. , vol.46 , pp. 157-168
    • Schmidtchen, A.1    Frick, I.M.2    Andersson, E.3    Tapper, H.4    Bjorck, L.5
  • 36
    • 0024214560 scopus 로고
    • Outer membrane proteins of polymyxin resistant Pseudomonas aeruginosa: Effect of magnesium depletion
    • Shand, G. H., H. Anwar, and M. R. Brown. 1988. Outer membrane proteins of polymyxin resistant Pseudomonas aeruginosa: effect of magnesium depletion. J. Antimicrob. Chemother. 22:811-821.
    • (1988) J. Antimicrob. Chemother. , vol.22 , pp. 811-821
    • Shand, G.H.1    Anwar, H.2    Brown, M.R.3
  • 38
    • 0029828327 scopus 로고    scopus 로고
    • Two-component regulatory systems can interact to process multiple environmental signals
    • Soncini, F. C., and E. A. Groisman. 1996. Two-component regulatory systems can interact to process multiple environmental signals. J. Bacteriol. 178:6796-6801.
    • (1996) J. Bacteriol. , vol.178 , pp. 6796-6801
    • Soncini, F.C.1    Groisman, E.A.2
  • 40
    • 0034730333 scopus 로고    scopus 로고
    • A signal transduction system that responds to extracellular iron
    • Wosten, M. M., L. F. Kox, S. Chamnongpol, F. C. Soncini, and E. A. Groisman. 2000. A signal transduction system that responds to extracellular iron. Cell 103:113-125.
    • (2000) Cell , vol.103 , pp. 113-125
    • Wosten, M.M.1    Kox, L.F.2    Chamnongpol, S.3    Soncini, F.C.4    Groisman, E.A.5
  • 41
    • 0035900684 scopus 로고    scopus 로고
    • Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PmrA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporation
    • Zhou, Z., A. A. Ribeiro, S. Lin, R. J. Cotter, S. I. Miller, and C. R. Raetz. 2001. Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PmrA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporation. J. Biol. Chem. 276:43111-43121.
    • (2001) J. Biol. Chem. , vol.276 , pp. 43111-43121
    • Zhou, Z.1    Ribeiro, A.A.2    Lin, S.3    Cotter, R.J.4    Miller, S.I.5    Raetz, C.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.