The host E3-ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication

Journal of Virology

Volumn 91, Issue 18, 2017, Pages

  Bharaj, Preeti ^a   Atkins, Colm ^a   Luthra, Priya ^b   Giraldo, Maria Isabel ^a   Dawes, Brian E ^a   Miorin, Lisa ^c   Johnson, Jeffrey R ^d   Krogan, Nevan J ^d   Basler, Christopher F ^b   Freiberg, Alexander N ^a   Rajsbaum, Ricardo ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ebola virus; Innate immunity; TRIM6; Tripartite motif (TRIM) protein; Ubiquitination; Unanchored ubiquitin; Viral RNA polymerase; Virus host interactions; VP35

Indexed keywords

TRIM6 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; UBIQUITIN PROTEIN LIGASE; VIRAL PROTEIN; VP35 PROTEIN, FILOVIRUS;

ANIMAL; CELL LINE; EBOLAVIRUS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOPRECIPITATION; MASS SPECTROMETRY; METABOLISM; PHYSIOLOGY; UBIQUITINATION; VIRUS REPLICATION;

ANIMALS; CELL LINE; EBOLAVIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRAL REGULATORY AND ACCESSORY PROTEINS; VIRUS REPLICATION;

EID: 85028324631     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00833-17     Document Type: Article

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