The L-VP35 and L-L interaction domains reside in the amino terminus of the Ebola virus L protein and are potential targets for antivirals

Virology

Volumn 441, Issue 2, 2013, Pages 135-145

  Trunschke, Martina ^a   Conrad, Dominik ^a,b,d   Enterlein, Sven ^c   Olejnik, Judith ^a,b   Brauburger, Kristina ^a,b   Mühlberger, Elke ^a,b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Integrated BioTherapeutics Inc   (United States)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Ebola virus; Ebolavirus; Filovirus; L protein; Negative sense RNA virus; Nucleocapsid; Polymerase complex; Replication; Ribonucleoprotein complex; RNA dependent RNA polymerase; VP35

Indexed keywords

ANTIVIRUS AGENT; EBOLA VIRUS L PROTEIN; PROTEIN VP35; RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; EBOLA VIRUS; GENE DELETION; GENETIC TRANSCRIPTION; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; VIRUS GENOME; VIRUS MUTANT; VIRUS REPLICATION;

ANIMALS; CELL LINE; EBOLAVIRUS; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NUCLEOPROTEINS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN MULTIMERIZATION; RNA REPLICASE; VIRAL CORE PROTEINS;

EBOLA VIRUS; MARBURGVIRUS; RNA VIRUSES;

EID: 84877920406     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.03.013     Document Type: Article

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