A C-terminal basic amino acid motif of Zaire ebolavirus VP35 is essential for type I interferon antagonism and displays high identity with the RNA-binding domain of another interferon antagonist, the NS1 protein of influenza a virus

Virology

Volumn 328, Issue 2, 2004, Pages 177-184

  Hartman, Amy L ^a   Towner, Jonathan S ^a   Nichol, Stuart T ^a  

^a Natl Ctr Infect Dis Centers D   (United States)

Author keywords

Ebolavirus; Filovirus; Hemorrhagic fever; Influenza; Interferon; NS1; VP35

Indexed keywords

INTERFERON; INTERFERON REGULATORY FACTOR 3; RNA; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMOCRATIC REPUBLIC CONGO; EBOLA VIRUS; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; INFLUENZA VIRUS A; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; REPORTER GENE; RNA BINDING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL LINE, TRANSFORMED; DNA-BINDING PROTEINS; EBOLAVIRUS; GENES, REPORTER; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PROTEINS;

EBOLA VIRUS; INFLUENZA A VIRUS; INFLUENZA VIRUS; MARBURG-LIKE VIRUSES; RNA VIRUSES; STAPHYLOCOCCUS PHAGE 3A; ZAIRE EBOLAVIRUS;

EID: 5344258197     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2004.07.006     Document Type: Article

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