-
1
-
-
84938086301
-
Quantification of biological aging in young adults
-
Belsky, D. W., Caspi, A., Houts, R., Cohen, H. J., Corcoran, D. L., Danese, A., et al. (2015). Quantification of biological aging in young adults. Proc. Natl. Acad. Sci. U.S.A. 112, E4104-E4110. doi: 10.1073/pnas.1506264112
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
, pp. E4104-E4110
-
-
Belsky, D.W.1
Caspi, A.2
Houts, R.3
Cohen, H.J.4
Corcoran, D.L.5
Danese, A.6
-
2
-
-
84991466905
-
DNA methylation-based measures of biological age: meta-analysis predicting time to death
-
Chen, B. H., Marioni, R. E., Colicino, E., Peters, M. J., Ward-Caviness, C. K., Tsai, P. C., et al. (2016). DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging (Albany NY) 8, 1844-1865. doi: 10.18632/aging.101020
-
(2016)
Aging (Albany NY)
, vol.8
, pp. 1844-1865
-
-
Chen, B.H.1
Marioni, R.E.2
Colicino, E.3
Peters, M.J.4
Ward-Caviness, C.K.5
Tsai, P.C.6
-
3
-
-
84955194730
-
DNA methylation age is associated with mortality in a longitudinal Danish twin study
-
Christiansen, L., Lenart, A., Tan, Q., Vaupel, J. W., Aviv, A., McGue, M., et al. (2016). DNA methylation age is associated with mortality in a longitudinal Danish twin study. Aging Cell 15, 149-154. doi: 10.1111/acel.12421
-
(2016)
Aging Cell
, vol.15
, pp. 149-154
-
-
Christiansen, L.1
Lenart, A.2
Tan, Q.3
Vaupel, J.W.4
Aviv, A.5
McGue, M.6
-
4
-
-
84863722178
-
Frailty phenotypes in the elderly based on cluster analysis: a longitudinal study of two Danish cohorts
-
Dato, S., Montesanto, A., Lagani, V., Jeune, B., Christensen, K., and Passarino, G. (2012). Frailty phenotypes in the elderly based on cluster analysis: a longitudinal study of two Danish cohorts. Evidence for a genetic influence on frailty. Age (Dordr) 34, 571-582. doi: 10.1007/s11357-011-9257-x
-
(2012)
Evidence for a genetic influence on frailty. Age (Dordr)
, vol.34
, pp. 571-582
-
-
Dato, S.1
Montesanto, A.2
Lagani, V.3
Jeune, B.4
Christensen, K.5
Passarino, G.6
-
5
-
-
0037338636
-
Morbidity profiles of centenarians: survivors, delayers, and escapers
-
Evert, J., Lawler, E., Bogan, H., and Perls, T. (2003). Morbidity profiles of centenarians: survivors, delayers, and escapers. J. Gerontol. A Biol. Sci. Med. Sci. 58, 232-237.
-
(2003)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.58
, pp. 232-237
-
-
Evert, J.1
Lawler, E.2
Bogan, H.3
Perls, T.4
-
6
-
-
2442699834
-
Frailty in older adults: evidence for a phenotype
-
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., et al. (2001). Frailty in older adults: evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 56, M146-M156.
-
(2001)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.56
, pp. M146-M156
-
-
Fried, L.P.1
Tangen, C.M.2
Walston, J.3
Newman, A.B.4
Hirsch, C.5
Gottdiener, J.6
-
7
-
-
77950478147
-
Trajectories of disability in the last year of life
-
Gill, T. M., Gahbauer, E. A., Han, L., and Allore, H. G. (2010). Trajectories of disability in the last year of life. N. Engl. J. Med. 362, 1173-1180. doi: 10.1056/NEJMoa0909087
-
(2010)
N. Engl. J. Med
, vol.362
, pp. 1173-1180
-
-
Gill, T.M.1
Gahbauer, E.A.2
Han, L.3
Allore, H.G.4
-
8
-
-
84872806231
-
Genome-wide methylation profiles reveal quantitative views of human aging rates
-
Hannum, G., Guinney, J., Zhao, L., Zhang, L., Hughes, G., Sadda, S., et al. (2013). Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol. Cell. 49, 359-367. doi: 10.1016/j.molcel.2012.10.016
-
(2013)
Mol. Cell
, vol.49
, pp. 359-367
-
-
Hannum, G.1
Guinney, J.2
Zhao, L.3
Zhang, L.4
Hughes, G.5
Sadda, S.6
-
9
-
-
84886111619
-
DNA methylation age of human tissues and cell types
-
Horvath, S. (2013). DNA methylation age of human tissues and cell types. Genome Biol. 14:R115. doi: 10.1186/gb-2013-14-10-r115
-
(2013)
Genome Biol
, vol.14
, pp. 115
-
-
Horvath, S.1
-
10
-
-
84957581421
-
Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring
-
Horvath, S., Pirazzini, C., Bacalini, M. G., Gentilini, D., Di Blasio, A. M., Delledonne, M., et al. (2015). Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring. Aging (Albany NY) 7, 1159-1170. doi: 10.18632/aging.100861
-
(2015)
Aging (Albany NY)
, vol.7
, pp. 1159-1170
-
-
Horvath, S.1
Pirazzini, C.2
Bacalini, M.G.3
Gentilini, D.4
Di Blasio, A.M.5
Delledonne, M.6
-
11
-
-
78349252738
-
HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging
-
Jazwinski, S. M., Kim, S., Dai, J., Li, L., Bi, X., Jiang, J. C., et al. (2010). HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging. Aging Cell 9, 698-708. doi: 10.1111/j.1474-9726.2010.00600.x
-
(2010)
Aging Cell
, vol.9
, pp. 698-708
-
-
Jazwinski, S.M.1
Kim, S.2
Dai, J.3
Li, L.4
Bi, X.5
Jiang, J.C.6
-
12
-
-
84861454781
-
Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity
-
Kim, S., Bi, X., Czarny-Ratajczak, M., Dai, J., Welsh, D. A., Myers, L., et al. (2012). Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity. Biogerontology 13, 119-131. doi: 10.1007/s10522-011-9360-5
-
(2012)
Biogerontology
, vol.13
, pp. 119-131
-
-
Kim, S.1
Bi, X.2
Czarny-Ratajczak, M.3
Dai, J.4
Welsh, D.A.5
Myers, L.6
-
13
-
-
84942837378
-
Quantitative measures of healthy aging and biological age
-
Kim, S., and Jazwinski, S. M. (2015). Quantitative measures of healthy aging and biological age. Healthy Aging Res. 4:26. doi: 10.12715/har.2015.4.26
-
(2015)
Healthy Aging Res
, vol.4
, pp. 26
-
-
Kim, S.1
Jazwinski, S.M.2
-
14
-
-
84960446048
-
Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians
-
Kim, S., Myers, L., Ravussin, E., Cherry, K. E., and Jazwinski, S. M. (2016a). Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians. Biogerontology 17, 725-736. doi: 10.1007/s10522-016-9643-y
-
(2016)
Biogerontology
, vol.17
, pp. 725-736
-
-
Kim, S.1
Myers, L.2
Ravussin, E.3
Cherry, K.E.4
Jazwinski, S.M.5
-
15
-
-
85017238668
-
The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age
-
Kim, S., Myers, L., Wyckoff, J., Cherry, K. E., and Jazwinski, S. M. (2017). The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age. GeroScience 39, 83-92. doi: 10.1007/s11357-017-9960-3
-
(2017)
GeroScience
, vol.39
, pp. 83-92
-
-
Kim, S.1
Myers, L.2
Wyckoff, J.3
Cherry, K.E.4
Jazwinski, S.M.5
-
16
-
-
84959210183
-
Programmed cell death genes are linked to elevated creatine kinase levels in unhealthy male nonagenarians
-
Kim, S., Simon, E., Myers, L., Hamm, L. L., and Jazwinski, S. M. (2016b). Programmed cell death genes are linked to elevated creatine kinase levels in unhealthy male nonagenarians. Gerontology 62, 519-529. doi: 10.1159/000443793
-
(2016)
Gerontology
, vol.62
, pp. 519-529
-
-
Kim, S.1
Simon, E.2
Myers, L.3
Hamm, L.L.4
Jazwinski, S.M.5
-
17
-
-
84892566609
-
Association of healthy aging with parental longevity
-
Kim, S., Welsh, D. A., Cherry, K. E., Myers, L., and Jazwinski, S. M. (2013). Association of healthy aging with parental longevity. Age (Dordr) 35, 1975-1982. doi: 10.1007/s11357-012-9472-0
-
(2013)
Age (Dordr)
, vol.35
, pp. 1975-1982
-
-
Kim, S.1
Welsh, D.A.2
Cherry, K.E.3
Myers, L.4
Jazwinski, S.M.5
-
18
-
-
84924261302
-
Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival
-
Kim, S., Welsh, D. A., Myers, L., Cherry, K. E., Wyckoff, J., and Jazwinski, S. M. (2015). Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival. Oncotarget 6, 3600-3612. doi: 10.18632/oncotarget.2877
-
(2015)
Oncotarget
, vol.6
, pp. 3600-3612
-
-
Kim, S.1
Welsh, D.A.2
Myers, L.3
Cherry, K.E.4
Wyckoff, J.5
Jazwinski, S.M.6
-
19
-
-
84901051037
-
An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively
-
Kim, S., Welsh, D. A., Ravussin, E., Welsch, M. A., Cherry, K. E., Myers, L., et al. (2014). An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively. J. Gerontol. A Biol. Sci. Med. Sci. 69, 650-656. doi: 10.1093/gerona/glt150
-
(2014)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.69
, pp. 650-656
-
-
Kim, S.1
Welsh, D.A.2
Ravussin, E.3
Welsch, M.A.4
Cherry, K.E.5
Myers, L.6
-
20
-
-
84878297204
-
Modeling the rate of senescence: can estimated biological age predict mortality more accurately than chronological age? J
-
Levine, M. E. (2013). Modeling the rate of senescence: can estimated biological age predict mortality more accurately than chronological age? J. Gerontol. A Biol. Sci. Med. Sci. 68, 667-674. doi: 10.1093/gerona/gls233
-
(2013)
Gerontol. A Biol. Sci. Med. Sci
, vol.68
, pp. 667-674
-
-
Levine, M.E.1
-
21
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin, C., Blasco, M. A., Partridge, L., Serrano, M., and Kroemer, G. (2013). The hallmarks of aging. Cell 153, 1194-1217. doi: 10.1016/j.cell.2013.05.039
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
22
-
-
84926674860
-
DNA methylation age of blood predicts all-cause mortality in later life
-
Marioni, R. E., Shah, S., McRae, A. F., Chen, B. H., Colicino, E., Harris, S. E., et al. (2015). DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol. 16:25. doi: 10.1186/s13059-015-0584-6
-
(2015)
Genome Biol
, vol.16
, pp. 25
-
-
Marioni, R.E.1
Shah, S.2
McRae, A.F.3
Chen, B.H.4
Colicino, E.5
Harris, S.E.6
-
23
-
-
84893941663
-
APOE 4, rated life experiences, and affect among centenarians
-
Martin, P., Jazwinski, S. M., Davey, A., Green, R. C., Macdonald, M., Margrett, J. A., et al. (2014). APOE 4, rated life experiences, and affect among centenarians. Aging Ment. Health 18, 240-247. doi: 10.1080/13607863.2013.827624
-
(2014)
Aging Ment. Health
, vol.18
, pp. 240-247
-
-
Martin, P.1
Jazwinski, S.M.2
Davey, A.3
Green, R.C.4
Macdonald, M.5
Margrett, J.A.6
-
24
-
-
78649600105
-
Heritability estimates of endophenotypes of long and health life: the Long Life Family Study
-
Matteini, A. M., Fallin, M. D., Kammerer, C. M., Schupf, N., Yashin, A. I., Christensen, K., et al. (2010). Heritability estimates of endophenotypes of long and health life: the Long Life Family Study. J. Gerontol. A Biol. Sci. Med. Sci. 65, 1375-1379. doi: 10.1093/gerona/glq154
-
(2010)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.65
, pp. 1375-1379
-
-
Matteini, A.M.1
Fallin, M.D.2
Kammerer, C.M.3
Schupf, N.4
Yashin, A.I.5
Christensen, K.6
-
25
-
-
81355138980
-
Longitudinal dynamic analyses of cognition in the health and retirement study panel
-
McArdle, J. J. (2011). Longitudinal dynamic analyses of cognition in the health and retirement study panel. Adv. Stat. Anal. 95, 453-480. doi: 10.1007/s10182-011-0168-z
-
(2011)
Adv. Stat. Anal
, vol.95
, pp. 453-480
-
-
McArdle, J.J.1
-
26
-
-
84949116267
-
Trajectories of physiological dysregulation predicts mortality and health outcomes in a consistent manner across three populations
-
Milot, E., Morissette-Thomas, V., Li, Q., Fried, L. P., Ferrucci, L., and Cohen, A. A. (2014). Trajectories of physiological dysregulation predicts mortality and health outcomes in a consistent manner across three populations. Mech. Ageing Dev. 14, 56-63. doi: 10.1016/j.mad.2014.10.001
-
(2014)
Mech. Ageing Dev
, vol.14
, pp. 56-63
-
-
Milot, E.1
Morissette-Thomas, V.2
Li, Q.3
Fried, L.P.4
Ferrucci, L.5
Cohen, A.A.6
-
27
-
-
0001296914
-
Accumulation of deficits as a proxy measure of aging
-
Mitnitski, A. B., Mogilner, A. J., and Rockwood, K. (2001). Accumulation of deficits as a proxy measure of aging. Sci. World J. 1, 323-336. doi: 10.1100/tsw.2001.58
-
(2001)
Sci. World J
, vol.1
, pp. 323-336
-
-
Mitnitski, A.B.1
Mogilner, A.J.2
Rockwood, K.3
-
28
-
-
84952637125
-
Aging-related magnification of genetic effects on cognitive and brain integrity
-
Papenberg, G., Lindenberger, U., and Backman, L. (2015). Aging-related magnification of genetic effects on cognitive and brain integrity. Trends Cogn. Sci. 19, 506-514. doi: 10.1016/j.tics.2015.06.008
-
(2015)
Trends Cogn. Sci
, vol.19
, pp. 506-514
-
-
Papenberg, G.1
Lindenberger, U.2
Backman, L.3
-
29
-
-
84876805007
-
The aging mind: neuroplasticity in response to cognitive training
-
Park, D. C., and Bischof, G. N. (2013). The aging mind: neuroplasticity in response to cognitive training. Dialogues Clin. Neurosci. 15, 109-119.
-
(2013)
Dialogues Clin. Neurosci
, vol.15
, pp. 109-119
-
-
Park, D.C.1
Bischof, G.N.2
-
30
-
-
84975246016
-
Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort
-
Perna, L., Zhang, Y., Mons, U., Holleczek, B., Saum, K. U., and Brenner, H. (2016). Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort. Clin. Epigenetics 8:64. doi: 10.1186/s13148-016-0228-z
-
(2016)
Clin. Epigenetics
, vol.8
, pp. 64
-
-
Perna, L.1
Zhang, Y.2
Mons, U.3
Holleczek, B.4
Saum, K.U.5
Brenner, H.6
-
31
-
-
34548459347
-
A comparison of two approaches to measuring frailty in elderly people
-
Rockwood, K., Andrew, M., and Mitnitski, A. (2007). A comparison of two approaches to measuring frailty in elderly people. J. Gerontol. A Biol. Sci. Med. Sci. 62, 738-743.
-
(2007)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.62
, pp. 738-743
-
-
Rockwood, K.1
Andrew, M.2
Mitnitski, A.3
-
33
-
-
0030811990
-
Successful aging
-
Rowe, J. W., and Kahn, R. L. (1997). Successful aging. Gerontologist 37, 433-440.
-
(1997)
Gerontologist
, vol.37
, pp. 433-440
-
-
Rowe, J.W.1
Kahn, R.L.2
-
34
-
-
85008403719
-
Biomarker signatures of aging
-
Sebastiani, P., Thyagarajan, B., Sun, F., Schupf, N., Newman, A. B., Montano, M., et al. (2017). Biomarker signatures of aging. Aging Cell 16, 329-338. doi: 10.1111/acel.12557
-
(2017)
Aging Cell
, vol.16
, pp. 329-338
-
-
Sebastiani, P.1
Thyagarajan, B.2
Sun, F.3
Schupf, N.4
Newman, A.B.5
Montano, M.6
-
35
-
-
0035836692
-
Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging
-
Seeman, T. E., McEwen, B. S., Rowe, J. W., and Singer, B. H. (2001). Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging. Proc. Natl. Acad. Sci. U.S.A. 98, 4770-4775. doi: 10.1073/pnas.081072698
-
(2001)
Proc. Natl. Acad. Sci. U.S.A
, vol.98
, pp. 4770-4775
-
-
Seeman, T.E.1
McEwen, B.S.2
Rowe, J.W.3
Singer, B.H.4
-
36
-
-
0014216401
-
Physical activity and the "rate of ageing." Can
-
Shock, N. W. (1967). Physical activity and the "rate of ageing." Can. Med. Assoc. J. 96, 836-842.
-
(1967)
Med. Assoc. J
, vol.96
, pp. 836-842
-
-
Shock, N.W.1
-
37
-
-
84962376897
-
The emergence of geroscience as an interdisciplinary approach to the enhancement of health span and life span
-
Sierra, F. (2016). The emergence of geroscience as an interdisciplinary approach to the enhancement of health span and life span. Cold Spring. Harb. Perspect. Med. 6, a025163. doi: 10.1101/cshperspect.a025163
-
(2016)
Cold Spring. Harb. Perspect. Med
, vol.6
-
-
Sierra, F.1
-
38
-
-
84904571964
-
Aging induced loss of complexity and dedifferentiation: consequences for coordination dynamics within and between brain, muscular and behavioral levels
-
Sleimen-Malkoun, R., Temprado, J. J., and Hong, S. L. (2014). Aging induced loss of complexity and dedifferentiation: consequences for coordination dynamics within and between brain, muscular and behavioral levels. Front. Aging. Neurosci. 6:140. doi: 10.3389/fnagi.2014.00140
-
(2014)
Front. Aging. Neurosci
, vol.6
, pp. 140
-
-
Sleimen-Malkoun, R.1
Temprado, J.J.2
Hong, S.L.3
-
39
-
-
84892928725
-
UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation
-
Vozza, A., Parisi, G., De Leonardis, F., Lasorsa, F. M., Castegna, A., Amorese, D., et al. (2014). UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation. Proc. Natl. Acad. Sci. U.S.A. 111, 960-965. doi: 10.1073/pnas.1317400111
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. 960-965
-
-
Vozza, A.1
Parisi, G.2
De Leonardis, F.3
Lasorsa, F.M.4
Castegna, A.5
Amorese, D.6
|