메뉴 건너뛰기




Volumn 201, Issue 4, 2012, Pages 581-592

Dendritic cells in Leishmania major infections: mechanisms of parasite uptake, cell activation and evidence for physiological relevance

Author keywords

Adaptive immunity; Dendritic cells; Leishmania; Skin immune system

Indexed keywords

FC RECEPTOR;

EID: 85027958306     PISSN: 03008584     EISSN: 14321831     Source Type: Journal    
DOI: 10.1007/s00430-012-0261-2     Document Type: Review
Times cited : (29)

References (92)
  • 1
    • 0033517487 scopus 로고    scopus 로고
    • Leishmaniasis
    • PID: 10513726, COI: 1:STN:280:DyaK1MvktFyrtg%3D%3D
    • Herwaldt BL (1999) Leishmaniasis. Lancet 354:1191–1199
    • (1999) Lancet , vol.354 , pp. 1191-1199
    • Herwaldt, B.L.1
  • 2
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • PID: 12415308, COI: 1:CAS:528:DC%2BD38Xotlers70%3D
    • Sacks D, Noben-Trauth N (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol 2:845–858
    • (2002) Nat Rev Immunol , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 3
    • 84859480329 scopus 로고    scopus 로고
    • Leishmaniasis in rheumatology, haematology and oncology: epidemiological, immunological and clinical aspects and caveats
    • Bogdan C (2012) Leishmaniasis in rheumatology, haematology and oncology: epidemiological, immunological and clinical aspects and caveats. Ann Rheum Dis 71:60–66
    • (2012) Ann Rheum Dis , vol.71 , pp. 60-66
    • Bogdan, C.1
  • 4
    • 33947413426 scopus 로고    scopus 로고
    • Immunology of cutaneous leishmaniasis: the role of mast cells, phagocytes and dendritic cells for protective immunity
    • *von Stebut E (2007) Immunology of cutaneous leishmaniasis: the role of mast cells, phagocytes and dendritic cells for protective immunity. Eur J Dermatol 17:115–122
    • (2007) Eur J Dermatol , vol.17 , pp. 115-122
    • von Stebut, E.1
  • 5
    • 0034661692 scopus 로고    scopus 로고
    • A natural model of Leishmania major infection reveals a prolonged “silent” phase of parasite amplification in the skin before the onset of lesion formation and immunity
    • PID: 10878373, COI: 1:CAS:528:DC%2BD3cXkvFWitrg%3D
    • Belkaid Y, Mendez S, Lira R, Kadambi N, Milon G, Sacks D (2000) A natural model of Leishmania major infection reveals a prolonged “silent” phase of parasite amplification in the skin before the onset of lesion formation and immunity. J Immunol 165:969–977
    • (2000) J Immunol , vol.165 , pp. 969-977
    • Belkaid, Y.1    Mendez, S.2    Lira, R.3    Kadambi, N.4    Milon, G.5    Sacks, D.6
  • 6
    • 70349916077 scopus 로고    scopus 로고
    • The impact of vector-mediated neutrophil recruitment on cutaneous leishmaniasis
    • PID: 19545276, COI: 1:CAS:528:DC%2BD1MXhtFSgurrJ
    • Peters NC, Sacks DL (2009) The impact of vector-mediated neutrophil recruitment on cutaneous leishmaniasis. Cell Microbiol 11:1290–1296
    • (2009) Cell Microbiol , vol.11 , pp. 1290-1296
    • Peters, N.C.1    Sacks, D.L.2
  • 7
    • 0032547859 scopus 로고    scopus 로고
    • Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity
    • *von Stebut E, Belkaid Y, Jakob T, Sacks DL, Udey MC (1998) Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity. J Exp Med 188:1547–1552
    • (1998) J Exp Med , vol.188 , pp. 1547-1552
    • von Stebut, E.1    Belkaid, Y.2    Jakob, T.3    Sacks, D.L.4    Udey, M.C.5
  • 8
    • 0034533054 scopus 로고    scopus 로고
    • Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis
    • *von Stebut E, Belkaid Y, Nguyen BV, Cushing M, Sacks DL, Udey MC (2000) Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis. Eur J Immunol 30:3498–3506
    • (2000) Eur J Immunol , vol.30 , pp. 3498-3506
    • von Stebut, E.1    Belkaid, Y.2    Nguyen, B.V.3    Cushing, M.4    Sacks, D.L.5    Udey, M.C.6
  • 9
    • 1642303398 scopus 로고    scopus 로고
    • Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection
    • PID: 14991601, COI: 1:CAS:528:DC%2BD2cXitlGgtrc%3D
    • Misslitz AC, Bonhagen K, Harbecke D, Lippuner C, Kamradt T, Aebischer T (2004) Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection. Eur J Immunol 34:715–725
    • (2004) Eur J Immunol , vol.34 , pp. 715-725
    • Misslitz, A.C.1    Bonhagen, K.2    Harbecke, D.3    Lippuner, C.4    Kamradt, T.5    Aebischer, T.6
  • 10
    • 1842484274 scopus 로고    scopus 로고
    • Dendritic cell populations in Leishmania major-infected skin and draining lymph nodes
    • PID: 15039319, COI: 1:CAS:528:DC%2BD2cXjt1eksbY%3D
    • Baldwin T, Henri S, Curtis J, O’Keeffe M, Vremec D, Shortman K, Handman E (2004) Dendritic cell populations in Leishmania major-infected skin and draining lymph nodes. Infect Immun 72:1991–2001
    • (2004) Infect Immun , vol.72 , pp. 1991-2001
    • Baldwin, T.1    Henri, S.2    Curtis, J.3    O’Keeffe, M.4    Vremec, D.5    Shortman, K.6    Handman, E.7
  • 11
    • 33947166288 scopus 로고    scopus 로고
    • Cutaneous Leishmania infection: progress in pathogenesis research and experimental therapy
    • *von Stebut E (2007) Cutaneous Leishmania infection: progress in pathogenesis research and experimental therapy. Exp Dermatol 16:340–346
    • (2007) Exp Dermatol , vol.16 , pp. 340-346
    • von Stebut, E.1
  • 14
    • 0027473217 scopus 로고
    • Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major
    • PID: 8421175, COI: 1:STN:280:DyaK3s7jt1eqsQ%3D%3D
    • Blank C, Fuchs H, Rappersberger K, Röllinghoff M, Moll H (1993) Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major. J Infect Dis 167:418–425
    • (1993) J Infect Dis , vol.167 , pp. 418-425
    • Blank, C.1    Fuchs, H.2    Rappersberger, K.3    Röllinghoff, M.4    Moll, H.5
  • 15
    • 0031739890 scopus 로고    scopus 로고
    • Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major
    • PID: 9842923
    • Flohé SB, Bauer C, Flohé S, Moll H (1998) Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major. Eur J Immunol 28:3800–3811
    • (1998) Eur J Immunol , vol.28 , pp. 3800-3811
    • Flohé, S.B.1    Bauer, C.2    Flohé, S.3    Moll, H.4
  • 16
    • 0032528348 scopus 로고    scopus 로고
    • Human dendritic cell (DC)-based anti-infective therapy: engineering DCs to secrete functional IFN-γ and IL-12
    • PID: 9670965, COI: 1:CAS:528:DyaK1cXksFGqs7w%3D
    • Ahuja SS, Mummidi S, Malech HL, Ahuja SK (1998) Human dendritic cell (DC)-based anti-infective therapy: engineering DCs to secrete functional IFN-γ and IL-12. J Immunol 161:868–876
    • (1998) J Immunol , vol.161 , pp. 868-876
    • Ahuja, S.S.1    Mummidi, S.2    Malech, H.L.3    Ahuja, S.K.4
  • 17
    • 0037090268 scopus 로고    scopus 로고
    • + T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major
    • PID: 11937556, COI: 1:CAS:528:DC%2BD38XivV2is7o%3D
    • + T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major. J Immunol 168:3992–4000
    • (2002) J Immunol , vol.168 , pp. 3992-4000
    • Belkaid, Y.1    von Stebut, E.2    Mendez, S.3    Lira, R.4    Caler, E.5    Bertholet, S.6    Udey, M.C.7    Sacks, D.8
  • 18
    • 0033830087 scopus 로고    scopus 로고
    • In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response
    • PID: 11009109
    • Schönlau F, Scharffetter-Kochanek K, Grabbe S, Pietz B, Sorg C, Sunderkötter C (2000) In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response. Eur J Immunol 30:2729–2740
    • (2000) Eur J Immunol , vol.30 , pp. 2729-2740
    • Schönlau, F.1    Scharffetter-Kochanek, K.2    Grabbe, S.3    Pietz, B.4    Sorg, C.5    Sunderkötter, C.6
  • 19
    • 84934436897 scopus 로고    scopus 로고
    • Self, non-self, and danger: a complementary view
    • PID: 16893066
    • Köhl J (2006) Self, non-self, and danger: a complementary view. Adv Exp Med Biol 586:71–94
    • (2006) Adv Exp Med Biol , vol.586 , pp. 71-94
    • Köhl, J.1
  • 20
    • 0344959468 scopus 로고    scopus 로고
    • Immune adherence-mediated opsonophagocytosis: the mechanism of Leishmania infection
    • PID: 9874561
    • Domínguez M, Toraño A (1999) Immune adherence-mediated opsonophagocytosis: the mechanism of Leishmania infection. J Exp Med 189:25–35
    • (1999) J Exp Med , vol.189 , pp. 25-35
    • Domínguez, M.1    Toraño, A.2
  • 21
    • 64849086164 scopus 로고    scopus 로고
    • IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice
    • PID: 19234200, COI: 1:CAS:528:DC%2BD1MXitFKhu7s%3D
    • *Lopez Kostka S, Dinges S, Griewank K, Iwakura Y, Udey MC, von Stebut E (2009) IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice. J Immunol 182:3039–3046
    • (2009) J Immunol , vol.182 , pp. 3039-3046
    • Lopez Kostka, S.1    Dinges, S.2    Griewank, K.3    Iwakura, Y.4    Udey, M.C.5    von Stebut, E.6
  • 22
    • 15444364277 scopus 로고    scopus 로고
    • A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
    • PID: 15753208, COI: 1:CAS:528:DC%2BD2MXisVWmsr0%3D
    • Miles SA, Conrad SM, Alves RG, Jeronimo SM, Mosser DM (2005) A role for IgG immune complexes during infection with the intracellular pathogen Leishmania. J Exp Med 201:747–754
    • (2005) J Exp Med , vol.201 , pp. 747-754
    • Miles, S.A.1    Conrad, S.M.2    Alves, R.G.3    Jeronimo, S.M.4    Mosser, D.M.5
  • 23
    • 85084719028 scopus 로고    scopus 로고
    • Primed by parasites
    • Editor’s Choice (2006) Primed by parasites. Science 311:579–581
    • (2006) Science , vol.311 , pp. 579-581
  • 24
    • 77951899942 scopus 로고    scopus 로고
    • Apoptosis and apoptotic mimicry: the Leishmania connection
    • PID: 20140747, COI: 1:CAS:528:DC%2BC3cXltVykt78%3D
    • Wanderley JL, Barcinski MA (2010) Apoptosis and apoptotic mimicry: the Leishmania connection. Cell Mol Life Sci 67:1653–1659
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1653-1659
    • Wanderley, J.L.1    Barcinski, M.A.2
  • 25
    • 31144454859 scopus 로고    scopus 로고
    • Mimicry of apoptotic cells by exposing phosphatidylserine participates in the establishment of amastigotes of Leishmania (L) amazonensis in mammalian hosts
    • PID: 16424214, COI: 1:CAS:528:DC%2BD28XlsFylug%3D%3D
    • Wanderley JL, Moreira ME, Benjamin A, Bonomo AC, Barcinski MA (2006) Mimicry of apoptotic cells by exposing phosphatidylserine participates in the establishment of amastigotes of Leishmania (L) amazonensis in mammalian hosts. J Immunol 176:1834–1839
    • (2006) J Immunol , vol.176 , pp. 1834-1839
    • Wanderley, J.L.1    Moreira, M.E.2    Benjamin, A.3    Bonomo, A.C.4    Barcinski, M.A.5
  • 26
    • 33845673298 scopus 로고    scopus 로고
    • Skin mast cells control T cell-dependent host defense in Leishmania major infections
    • PID: 17142795, COI: 1:CAS:528:DC%2BD28Xht1OmsLjL
    • *Maurer M, Lopez Kostka S, Siebenhaar F, Moelle K, Metz M, Knop J, von Stebut E (2006) Skin mast cells control T cell-dependent host defense in Leishmania major infections. FASEB J 20:2460–2467
    • (2006) FASEB J , vol.20 , pp. 2460-2467
    • Maurer, M.1    Lopez Kostka, S.2    Siebenhaar, F.3    Moelle, K.4    Metz, M.5    Knop, J.6    von Stebut, E.7
  • 27
    • 0028211512 scopus 로고
    • Mast cells augment lesion size and persistence during experimental Leishmania major infection in the mouse
    • PID: 8157970, COI: 1:STN:280:DyaK2c3gvFKktQ%3D%3D
    • Wershil BK, Theodos CM, Galli SJ, Titus RG (1994) Mast cells augment lesion size and persistence during experimental Leishmania major infection in the mouse. J Immunol 152:4563–4571
    • (1994) J Immunol , vol.152 , pp. 4563-4571
    • Wershil, B.K.1    Theodos, C.M.2    Galli, S.J.3    Titus, R.G.4
  • 29
    • 0021149185 scopus 로고
    • Tissue eosinophilia and Leishmania mexicana eosinophil interactions in murine cutaneous leishmaniasis
    • PID: 6504555
    • Grimaldi G Jr, Soares MJ, Moriearty PL (1984) Tissue eosinophilia and Leishmania mexicana eosinophil interactions in murine cutaneous leishmaniasis. Parasite Immunol 6:397–408
    • (1984) Parasite Immunol , vol.6 , pp. 397-408
    • Grimaldi, G.1    Soares, M.J.2    Moriearty, P.L.3
  • 30
    • 34548757393 scopus 로고    scopus 로고
    • Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B
    • PID: 17767162, COI: 1:CAS:528:DC%2BD2sXhtVCkurnL
    • Grimbaldeston MA, Nakae S, Kalesnikoff J, Tsai M, Galli SJ (2007) Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. Nat Immunol 8:1095–1104
    • (2007) Nat Immunol , vol.8 , pp. 1095-1104
    • Grimbaldeston, M.A.1    Nakae, S.2    Kalesnikoff, J.3    Tsai, M.4    Galli, S.J.5
  • 31
    • 79959754041 scopus 로고    scopus 로고
    • Mast cells promote Th1 and Th17 responses by modulating dendritic cell maturation and function
    • PID: 21491417, COI: 1:CAS:528:DC%2BC3MXnvF2gtL0%3D
    • *Dudeck A, Suender CA, Kostka SL, von Stebut E, Maurer M (2011) Mast cells promote Th1 and Th17 responses by modulating dendritic cell maturation and function. Eur J Immunol 41:1883–1893
    • (2011) Eur J Immunol , vol.41 , pp. 1883-1893
    • Dudeck, A.1    Suender, C.A.2    Kostka, S.L.3    von Stebut, E.4    Maurer, M.5
  • 33
    • 41649111226 scopus 로고    scopus 로고
    • Neutrophil granulocytes as host cells and transport vehicles for intracellular pathogens: apoptosis as infection-promoting factor
    • PID: 18406366, COI: 1:CAS:528:DC%2BD1cXnsVGmsLY%3D
    • Laskay T, van Zandbergen G, Solbach W (2008) Neutrophil granulocytes as host cells and transport vehicles for intracellular pathogens: apoptosis as infection-promoting factor. Immunobiology 213:183–191
    • (2008) Immunobiology , vol.213 , pp. 183-191
    • Laskay, T.1    van Zandbergen, G.2    Solbach, W.3
  • 34
    • 49649090356 scopus 로고    scopus 로고
    • Immunology. Neutrophil soldiers or Trojan Horses?
    • PID: 18703727, COI: 1:CAS:528:DC%2BD1cXhtVamsL7P
    • John B, Hunter CA (2008) Immunology. Neutrophil soldiers or Trojan Horses? Science 321:917–918
    • (2008) Science , vol.321 , pp. 917-918
    • John, B.1    Hunter, C.A.2
  • 35
    • 84860895881 scopus 로고    scopus 로고
    • Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-Leishmania response
    • PID: 22359507, COI: 1:CAS:528:DC%2BC38Xjt1SjtLs%3D
    • Ribeiro-Gomes FL, Peters NC, Debrabant A, Sacks DL (2012) Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-Leishmania response. PLoS Pathog 8:e1002536
    • (2012) PLoS Pathog , vol.8
    • Ribeiro-Gomes, F.L.1    Peters, N.C.2    Debrabant, A.3    Sacks, D.L.4
  • 36
    • 0037220342 scopus 로고    scopus 로고
    • Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1α/β released from neutrophils recruited by mast cell-derived TNFα
    • *von Stebut E, Metz M, Milon G, Knop J, Maurer M (2003) Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1α/β released from neutrophils recruited by mast cell-derived TNFα. Blood 101:210–215
    • (2003) Blood , vol.101 , pp. 210-215
    • von Stebut, E.1    Metz, M.2    Milon, G.3    Knop, J.4    Maurer, M.5
  • 37
    • 33646062612 scopus 로고    scopus 로고
    • Mast cell-associated TNF promotes dendritic cell migration
    • PID: 16547246, COI: 1:CAS:528:DC%2BD28Xis1erurc%3D
    • Suto H, Nakae S, Kakurai M, Sedgwick JD, Tsai M, Galli SJ (2006) Mast cell-associated TNF promotes dendritic cell migration. J Immunol 176:4102–4112
    • (2006) J Immunol , vol.176 , pp. 4102-4112
    • Suto, H.1    Nakae, S.2    Kakurai, M.3    Sedgwick, J.D.4    Tsai, M.5    Galli, S.J.6
  • 38
    • 1842684988 scopus 로고    scopus 로고
    • Immune sensitization in the skin is enhanced by antigen-independent effects of IgE
    • PID: 15084268, COI: 1:CAS:528:DC%2BD2cXjs1Gksb4%3D
    • Bryce PJ, Miller ML, Miyajima I, Tsai M, Galli SJ, Oettgen HC (2004) Immune sensitization in the skin is enhanced by antigen-independent effects of IgE. Immunity 20:381–392
    • (2004) Immunity , vol.20 , pp. 381-392
    • Bryce, P.J.1    Miller, M.L.2    Miyajima, I.3    Tsai, M.4    Galli, S.J.5    Oettgen, H.C.6
  • 39
    • 6344275820 scopus 로고    scopus 로고
    • IgE-mediated mast cell activation induces Langerhans cell migration in vivo
    • PID: 15470073, COI: 1:CAS:528:DC%2BD2cXotFGjs7o%3D
    • Jawdat DM, Albert EJ, Rowden G, Haidl ID, Marshall JS (2004) IgE-mediated mast cell activation induces Langerhans cell migration in vivo. J Immunol 173:5275–5282
    • (2004) J Immunol , vol.173 , pp. 5275-5282
    • Jawdat, D.M.1    Albert, E.J.2    Rowden, G.3    Haidl, I.D.4    Marshall, J.S.5
  • 40
    • 0032825739 scopus 로고    scopus 로고
    • Mast cell-T cell interactions
    • PID: 10482820, COI: 1:CAS:528:DyaK1MXmslKku78%3D
    • Mekori YA, Metcalfe DD (1999) Mast cell-T cell interactions. J Allergy Clin Immunol 104:517–523
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 517-523
    • Mekori, Y.A.1    Metcalfe, D.D.2
  • 41
    • 34249713187 scopus 로고    scopus 로고
    • Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections
    • PID: 17289816, COI: 1:CAS:528:DC%2BD2sXmt1OgurY%3D
    • Nakano N, Nishiyama C, Kanada S, Niwa Y, Shimokawa N, Ushio H, Nishiyama M, Okumura K, Ogawa H (2007) Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections. Blood 109:4846–4855
    • (2007) Blood , vol.109 , pp. 4846-4855
    • Nakano, N.1    Nishiyama, C.2    Kanada, S.3    Niwa, Y.4    Shimokawa, N.5    Ushio, H.6    Nishiyama, M.7    Okumura, K.8    Ogawa, H.9
  • 42
    • 0021037818 scopus 로고
    • Murine cutaneous leishmaniasis: resistance in reconstituted nude mice and several F1 hybrids infected with Leishmania tropica major
    • PID: 6606002, COI: 1:STN:280:DyaL2c%2FmtlSqsw%3D%3D
    • Mitchell GF (1983) Murine cutaneous leishmaniasis: resistance in reconstituted nude mice and several F1 hybrids infected with Leishmania tropica major. J Immunogenet 10:395–412
    • (1983) J Immunogenet , vol.10 , pp. 395-412
    • Mitchell, G.F.1
  • 43
    • 0025820205 scopus 로고
    • Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- and Th2-like lines
    • PID: 1831830, COI: 1:CAS:528:DyaK3MXmsFequ7w%3D
    • Holaday BJ, Sadick MD, Wang Z-E, Reiner SL, Heinzel FP, Parslow TG, Locksley RM (1991) Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- and Th2-like lines. J Immunol 147:1653–1658
    • (1991) J Immunol , vol.147 , pp. 1653-1658
    • Holaday, B.J.1    Sadick, M.D.2    Wang, Z.-E.3    Reiner, S.L.4    Heinzel, F.P.5    Parslow, T.G.6    Locksley, R.M.7
  • 44
    • 0027488625 scopus 로고
    • Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice
    • PID: 8367726, COI: 1:CAS:528:DyaK3sXmtVWgtL0%3D
    • Locksley RM, Reiner SL, Hatam F, Littman DR, Killeen N (1993) Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice. Science 261:1448–1451
    • (1993) Science , vol.261 , pp. 1448-1451
    • Locksley, R.M.1    Reiner, S.L.2    Hatam, F.3    Littman, D.R.4    Killeen, N.5
  • 45
    • 0022400673 scopus 로고
    • Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice
    • PID: 3926895, COI: 1:STN:280:DyaL2M3mt12itw%3D%3D
    • Titus RG, Ceredig R, Cerottini JC, Louis JA (1985) Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice. J Immunol 135:2108–2114
    • (1985) J Immunol , vol.135 , pp. 2108-2114
    • Titus, R.G.1    Ceredig, R.2    Cerottini, J.C.3    Louis, J.A.4
  • 49
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets
    • PID: 2521244, COI: 1:CAS:528:DyaL1MXntlKnsw%3D%3D
    • Heinzel FP, Sadick MD, Holaday BJ, Coffman RL, Locksley RM (1989) Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J Exp Med 169:59–72
    • (1989) J Exp Med , vol.169 , pp. 59-72
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Coffman, R.L.4    Locksley, R.M.5
  • 50
    • 0028235914 scopus 로고
    • + T cells following secondary infection of mice immune to Leishmania major
    • PID: 8188380
    • + T cells following secondary infection of mice immune to Leishmania major. Infect Immun 62:2575–2581
    • (1994) Infect Immun , vol.62 , pp. 2575-2581
    • Müller, I.1    Kropf, P.2    Louis, J.A.3    Milon, G.4
  • 54
    • 0023521281 scopus 로고
    • Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies
    • PID: 3119761, COI: 1:STN:280:DyaL1c%2FmtFSkug%3D%3D
    • Macatonia SE, Knight SC, Edwards AJ, Griffiths S, Fryer P (1987) Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies. J Exp Med 166:1654–1667
    • (1987) J Exp Med , vol.166 , pp. 1654-1667
    • Macatonia, S.E.1    Knight, S.C.2    Edwards, A.J.3    Griffiths, S.4    Fryer, P.5
  • 55
    • 0025130986 scopus 로고
    • Migration and maturation of Langerhans cells in skin transplants and explants
    • PID: 2230654, COI: 1:STN:280:DyaK3M%2Fjslyisw%3D%3D
    • Larsen CP, Steinman RM, Witmer-Pack M, Hankins DF, Morris PJ, Austyn JM (1990) Migration and maturation of Langerhans cells in skin transplants and explants. J Exp Med 172:1483
    • (1990) J Exp Med , vol.172 , pp. 1483
    • Larsen, C.P.1    Steinman, R.M.2    Witmer-Pack, M.3    Hankins, D.F.4    Morris, P.J.5    Austyn, J.M.6
  • 56
    • 0025147473 scopus 로고
    • Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization
    • PID: 2212665, COI: 1:CAS:528:DyaK3MXkslSn
    • Kripke ML, Munn CG, Jeevan A, Tang JM, Bucana CJ (1990) Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J Immunol 145:2833–2838
    • (1990) J Immunol , vol.145 , pp. 2833-2838
    • Kripke, M.L.1    Munn, C.G.2    Jeevan, A.3    Tang, J.M.4    Bucana, C.J.5
  • 57
    • 0034679791 scopus 로고    scopus 로고
    • CC chemokine receptor (CCR) 2 is required for Langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation
    • PID: 10899907, COI: 1:CAS:528:DC%2BD3cXkvFGiurc%3D
    • Sato N, Ahuja SK, Quinones M, Kostecki V, Reddick RL, Melby PC, Kuziel WA, Ahuja SS (2000) CC chemokine receptor (CCR) 2 is required for Langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation. J Exp Med 192:205–218
    • (2000) J Exp Med , vol.192 , pp. 205-218
    • Sato, N.1    Ahuja, S.K.2    Quinones, M.3    Kostecki, V.4    Reddick, R.L.5    Melby, P.C.6    Kuziel, W.A.7    Ahuja, S.S.8
  • 58
    • 0027248719 scopus 로고
    • Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells
    • PID: 8325337, COI: 1:STN:280:DyaK3szhsVOjtg%3D%3D
    • Moll H, Fuchs H, Blank C, Röllinghoff M (1993) Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells. Eur J Immunol 23:1595–1601
    • (1993) Eur J Immunol , vol.23 , pp. 1595-1601
    • Moll, H.1    Fuchs, H.2    Blank, C.3    Röllinghoff, M.4
  • 60
    • 0030021084 scopus 로고    scopus 로고
    • Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
    • PID: 8627163, COI: 1:CAS:528:DyaK28Xht1Snt7w%3D
    • Carrera L, Gazzinelli RT, Badolato R, Hieny S, Müller W, Kühn R, Sacks DL (1996) Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J Exp Med 183:515–526
    • (1996) J Exp Med , vol.183 , pp. 515-526
    • Carrera, L.1    Gazzinelli, R.T.2    Badolato, R.3    Hieny, S.4    Müller, W.5    Kühn, R.6    Sacks, D.L.7
  • 61
    • 84934435892 scopus 로고    scopus 로고
    • Class II MHC antigen processing in phagosomes
    • PID: 18425462, COI: 1:CAS:528:DC%2BD1cXmsV2ls7c%3D
    • Ramachandra L, Boom WH, Harding CV (2008) Class II MHC antigen processing in phagosomes. Methods Mol Biol 445:353–377
    • (2008) Methods Mol Biol , vol.445 , pp. 353-377
    • Ramachandra, L.1    Boom, W.H.2    Harding, C.V.3
  • 64
    • 0034684659 scopus 로고    scopus 로고
    • − dendritic cells cross-prime cytotoxic T cells in vivo
    • − dendritic cells cross-prime cytotoxic T cells in vivo. J Exp Med 192:1685–1696
    • (2000) J Exp Med , vol.192 , pp. 1685-1696
    • den Haan, J.M.1    Lehar, S.M.2    Bevan, M.J.3
  • 65
    • 0035290730 scopus 로고    scopus 로고
    • Antigen processing by the proteasome
    • PID: 11265247, COI: 1:CAS:528:DC%2BD3MXhvFKrs7w%3D
    • Kloetzel PM (2001) Antigen processing by the proteasome. Nat Rev Mol Cell Biol 2:179–187
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 179-187
    • Kloetzel, P.M.1
  • 66
    • 0037124367 scopus 로고    scopus 로고
    • Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells
    • PID: 12070293, COI: 1:CAS:528:DC%2BD38XkslWht7c%3D
    • Kalergis AM, Ravetch JV (2002) Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells. J Exp Med 195:1653–1659
    • (2002) J Exp Med , vol.195 , pp. 1653-1659
    • Kalergis, A.M.1    Ravetch, J.V.2
  • 70
    • 0027309318 scopus 로고
    • Resolution of cutaneous leishmaniasis: interleukin-12 initiates a protective T helper type 1 immune response
    • PID: 8098733, COI: 1:CAS:528:DyaK3sXitFWisb4%3D
    • Sypek JP, Chung CL, Mayor SE, Subramanyam JM, Goldman SJ, Sieburth DS, Wolf SF, Schaub RG (1993) Resolution of cutaneous leishmaniasis: interleukin-12 initiates a protective T helper type 1 immune response. J Exp Med 177:1797–1802
    • (1993) J Exp Med , vol.177 , pp. 1797-1802
    • Sypek, J.P.1    Chung, C.L.2    Mayor, S.E.3    Subramanyam, J.M.4    Goldman, S.J.5    Sieburth, D.S.6    Wolf, S.F.7    Schaub, R.G.8
  • 71
    • 0027528795 scopus 로고
    • Recombinant interleukin-12 cures mice infected with Leishmania major
    • PID: 8097524, COI: 1:CAS:528:DyaK3sXitFWisbs%3D
    • Heinzel FP, Schoenhaut DS, Rerko RM, Rosser LE, Gately MK (1993) Recombinant interleukin-12 cures mice infected with Leishmania major. J Exp Med 177:1505–1509
    • (1993) J Exp Med , vol.177 , pp. 1505-1509
    • Heinzel, F.P.1    Schoenhaut, D.S.2    Rerko, R.M.3    Rosser, L.E.4    Gately, M.K.5
  • 72
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • PID: 8766560, COI: 1:CAS:528:DyaK28Xkt1Chtbk%3D
    • Mattner F, Magram J, Ferrante J, Launois P, Di Padova K, Behin R, Gately MK, Louis JA, Alber G (1996) Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol 26:1553–1559
    • (1996) Eur J Immunol , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Launois, P.4    Di Padova, K.5    Behin, R.6    Gately, M.K.7    Louis, J.A.8    Alber, G.9
  • 73
    • 0029076809 scopus 로고
    • Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice
    • PID: 7608551, COI: 1:CAS:528:DyaK2MXmvVagsLw%3D
    • Heinzel FP, Rerko RM, Ahmed F, Pearlman E (1995) Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice. J Immunol 155:730–739
    • (1995) J Immunol , vol.155 , pp. 730-739
    • Heinzel, F.P.1    Rerko, R.M.2    Ahmed, F.3    Pearlman, E.4
  • 74
    • 79959729259 scopus 로고    scopus 로고
    • Research in practice: different dendritic cell types in skin with various functions—important implications for intradermal vaccines
    • *von Stebut E (2011) Research in practice: different dendritic cell types in skin with various functions—important implications for intradermal vaccines. J Dtsch Dermatol Ges 9:506–509
    • (2011) J Dtsch Dermatol Ges , vol.9 , pp. 506-509
    • von Stebut, E.1
  • 76
    • 33644828391 scopus 로고    scopus 로고
    • Development of dendritic cell system
    • PID: 16212897
    • Wu L, Dakic A (2004) Development of dendritic cell system. Cell Mol Immunol 1:112–118
    • (2004) Cell Mol Immunol , vol.1 , pp. 112-118
    • Wu, L.1    Dakic, A.2
  • 78
    • 34247104151 scopus 로고    scopus 로고
    • Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania
    • PID: 17412618, COI: 1:CAS:528:DC%2BD2sXltVKjsL4%3D
    • Leon B, Lopez-Bravo M, Ardavin C (2007) Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 26:519–531
    • (2007) Immunity , vol.26 , pp. 519-531
    • Leon, B.1    Lopez-Bravo, M.2    Ardavin, C.3
  • 82
    • 33644532959 scopus 로고    scopus 로고
    • Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells
    • PID: 16297200, COI: 1:CAS:528:DC%2BD2MXht1GrtrrP
    • Douillard P, Stoitzner P, Tripp CH, Clair-Moninot V, Ait-Yahia S, McLellan AD, Eggert A, Romani N, Saeland S (2005) Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells. J Invest Dermatol 125:983–994
    • (2005) J Invest Dermatol , vol.125 , pp. 983-994
    • Douillard, P.1    Stoitzner, P.2    Tripp, C.H.3    Clair-Moninot, V.4    Ait-Yahia, S.5    McLellan, A.D.6    Eggert, A.7    Romani, N.8    Saeland, S.9
  • 87
    • 22344443257 scopus 로고    scopus 로고
    • Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity
    • PID: 15897263, COI: 1:CAS:528:DC%2BD2MXksFyqs7k%3D
    • Bennett CL, van Rijn E, Jung S, Inaba K, Steinman RM, Kapsenberg ML, Clausen BE (2005) Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. J Cell Biol 169:569–576
    • (2005) J Cell Biol , vol.169 , pp. 569-576
    • Bennett, C.L.1    van Rijn, E.2    Jung, S.3    Inaba, K.4    Steinman, R.M.5    Kapsenberg, M.L.6    Clausen, B.E.7
  • 90
    • 0041488744 scopus 로고    scopus 로고
    • Interleukin 1α promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice
    • *von Stebut E, Ehrchen JM, Belkaid Y, Kostka SL, Molle K, Knop J, Sunderkotter C, Udey MC (2003) Interleukin 1α promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice. J Exp Med 198:191–199
    • (2003) J Exp Med , vol.198 , pp. 191-199
    • von Stebut, E.1    Ehrchen, J.M.2    Belkaid, Y.3    Kostka, S.L.4    Molle, K.5    Knop, J.6    Sunderkotter, C.7    Udey, M.C.8
  • 91
    • 0042991289 scopus 로고    scopus 로고
    • + T cell polarization in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells
    • PID: 12860929, COI: 1:CAS:528:DC%2BD3sXlvVyjtLY%3D
    • + T cell polarization in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells. J Exp Med 198:201–209
    • (2003) J Exp Med , vol.198 , pp. 201-209
    • Filippi, C.1    Hugues, S.2    Cazareth, J.3    Julia, V.4    Glaichenhaus, N.5    Ugolini, S.6
  • 92
    • 17444387109 scopus 로고    scopus 로고
    • Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major
    • PID: 15756639, COI: 1:CAS:528:DC%2BD2MXjslSgtLs%3D
    • *Zahn S, Wirtz S, Birkenbach M, Blumberg RS, Neurath MF, von Stebut E (2005) Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major. Eur J Immunol 35:1106–1112
    • (2005) Eur J Immunol , vol.35 , pp. 1106-1112
    • Zahn, S.1    Wirtz, S.2    Birkenbach, M.3    Blumberg, R.S.4    Neurath, M.F.5    von Stebut, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.