CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells: Absence of CCR2 shifts the Leishmania major - Resistant phenotype to a susceptible state dominated by Th2 cytokines, B cell outgrowth, and sustained neutrophilic inflammation

Journal of Experimental Medicine

Volumn 192, Issue 2, 2000, Pages 205-218

  Sato, Naoko ^a   Ahuja, Sunil K ^a   Quinones, Marion ^a   Kostecki, Vannessa ^a   Reddick, Robert L ^a   Melby, Peter C ^a   Kuziel, William A ^b   Ahuja, Seema S ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Chemokine; Cytokine; Infectious immunity; Knockout; T helper cell

Indexed keywords

CD8 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CYTOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CELL MIGRATION; CELLULAR DISTRIBUTION; DENDRITIC CELL; HELPER CELL; IMMUNE RESPONSE; KNOCKOUT MOUSE; LANGERHANS CELL; LEISHMANIA MAJOR; MOUSE; NONHUMAN; PARASITOSIS; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; B-LYMPHOCYTES; CELL MOVEMENT; CHEMOKINES, CXC; DENDRITIC CELLS; LANGERHANS CELLS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CYTOKINE; TH1 CELLS; TH2 CELLS;

EID: 0034679791     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.2.205     Document Type: Article

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