An amino acid-based amphoteric liposomal delivery system for systemic administration of siRNA

Molecular Therapy

Volumn 19, Issue 6, 2011, Pages 1141-1151

  Adami, Roger C ^a   Seth, Shaguna ^a   Harvie, Pierrot ^a   Johns, Rachel ^a   Fam, Renata ^a   Fosnaugh, Kathy ^a   Zhu, Tianying ^a   Farber, Ken ^a   McCutcheon, Michael ^a   Goodman, Thomas T ^a   Liu, Yan ^a   Chen, Yan ^a   Kwang, Erin ^a   Templin, Michael V ^a   Severson, Greg ^a   Brown, Tod ^a   Vaish, Narendra ^a   Chen, Feng ^a   Charmley, Patrick ^a   Polisky, Barry ^a   Houston, Michael E ^a   more..

^a Marina Biotech Inc ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINO ACID; APOLIPOPROTEIN B; ARGININE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL HYDROGEN SUCCINATE; CREATININE; LIPOSOME; NITROGEN; PREALBUMIN; SMALL INTERFERING RNA; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKYLATION; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG RELEASE; DRUG TOLERABILITY; ENDOSOME; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER TOXICITY; MAXIMUM PLASMA CONCENTRATION; MOUSE; NEPHROTOXICITY; NONHUMAN; PARTICLE SIZE; PH; PHASE TRANSITION; RNA INTERFERENCE; SINGLE DRUG DOSE; WEIGHT CHANGE;

ANIMALIA; MUS;

EID: 85027927478     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.56     Document Type: Article

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