Chitosan-Gellan Gum Bipolymeric Nanohydrogels—a Potential Nanocarrier for the Delivery of Epigallocatechin Gallate

BioNanoScience

Volumn 7, Issue 3, 2017, Pages 508-520

  Dahiya, Shakti ^a   Rani, Ruma ^a   Kumar, Sandeep ^a   Dhingra, Dinesh ^a   Dilbaghi, Neeraj ^a  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

( ) Epigallocatechin gallate; Antibacterial; Antioxidant; Nanohydrogels; Sustained release; Swelling behavior

Indexed keywords

ANTIOXIDANTS; CHITIN; CHITOSAN; CROSSLINKING; DRUG PRODUCTS; ENCAPSULATION; GELATION; HYDROPHILICITY; IONOTROPIC GELATION; NANOTECHNOLOGY; PARTICLE SIZE; POLYELECTROLYTES; POLYMERS;

ANTIBACTERIAL; EPIGALLOCATECHIN GALLATE; NANOHYDROGELS; SUSTAINED RELEASE; SWELLING BEHAVIOR;

DRUG DOSAGE;

EID: 85027859427     PISSN: 21911630     EISSN: 21911649     Source Type: Journal    
DOI: 10.1007/s12668-017-0416-0     Document Type: Article

References (49)

1. Lu, J. M., Lin, P. H., Qizhi, Y. Q., & Chen, C. (2010). Chemical and molecular mechanisms of antioxidants: Experimental approaches and model systems. Journal of Cellular and Molecular Medicine, 14(4), 840–860. doi:10.1111/j.1582-4934.2009.00897.x.
2. Pham-Huy, L. A., He, H., & Pham-Huy, C. (2008). Free radicals, antioxidants in disease and health. International Journal of Biomedical Sciences, 4, 89–96.
3. Cabrera, C., Artacho, R., & Giménez, R. (2006). Beneficial effects of green tea—a review. The Journal of the American College of Nutrition, 25, 79–99. doi:10.1080/07315724.2006.10719518.
4. Sajilata, M. G., Bajaj, P. R., & Singhal, R. S. (2008). Tea polyphenols as nutraceuticals. Comprehensive Reviews in Food Science and Food Safety, 7, 229–254. doi:10.1111/j.1541-4337.2008.00043.x.
5. Cai, Y., Anavy, N. D., & Chow, H. H. (2002). Contribution of presystemic hepatic extraction to the low oral bioavailability of green tea catechins in rats. Drug Metabolism & Disposition, 30, 1246–1249. doi:10.1124/dmd.30.11.1246.
6. Su, Y. L., Leung, L. K., Huang, Y., & Chen, Z. Y. (2003). Stability of tea theaflavins and catechins. Food Chemistry, 83, 189–195. doi:10.1016/S0308-8146(03)00062-1.
7. Kadowaki, M., Sugihara, N., Tagashira, T., Terao, K., & Furuno, K. (2008). Presence or absence of a gallate moiety on catechins affects their cellular transport. Journal of Pharmacy and Pharmacology, 60, 1189–1195. doi:10.1211/jpp.60.9.0011.
8. Neilson, A. P., Hopf, A. S., Cooper, B. R., Pereira, M. A., Bomser, J. A., & Ferruzzi, M. G. (2007). Catechin degradation with concurrent formation of homo-and hetero-catechin dimmers during in vitro digestion. Journal of Agricultural and Food Chemistry, 55, 8941–8949. doi:10.1021/jf071645m.
9. Qian, Z. Y., Fu, S. H., & Feng, S. S. (2013). Nanohydrogels as a prospective member of the nanomedicine family. Nanomedicine, 8(2), 161–164. doi:10.2217/nnm.13.1.
10. Reis, C. P., Neufeld, R. J., Ribeiro, A. J., & Veiga, F. (2006). Nanoencapsulation I. Methods for preparation of drug- loaded polymeric nanoparticles. Nanomedicine, 2, 8–21.
11. Hu, B., Ting, Y., Zeng, X., & Huang, Q. (2012). Cellular uptake and cytotoxicity of chitosan-caseinophosphopeptides nanocomplexes loaded with epigallocatchin gallate. Carbohydrate Polymers, 89, 362–370. doi:10.1016/j.carbpol.2012.03.015.
12. Bao, S., Xu, S., & Wang, Z. (2009). Antioxidant activity and properties of gelatin films incorporated with tea polyphenol-loaded chitosan nanoparticles. Journal of Agricultural and Food Chemistry, 89, 2692–2700. doi:10.1002/jsfa.3775.
13. Fang, J. J., Guan, R. F., Ma, J. Q., Rui, C., Shen, H. T., & Zhang, J. J. (2013). Optimization of fabrication parameters to prepare tea catechin-loaded liposomes using response surface methodology. Advance Journal of Food Science and Technology, 5, 29–35. doi:10.4028/www.scientific.net/KEM.531-532.458.
14. Kidd, P. M. (2005). Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts. Alternative Medicine Review, 14, 226–246.
15. Shpigelman, A., Cohen, Y., & Livney, Y. D. (2012). Thermally-induced β-lactoglobulin-EGCG nanovehicles: loading, stability, sensory and digestive release study. Food Hydrocolloids, 29, 57–67. doi:10.1016/j.foodhyd.2012.01.016.
16. Li, J., & Wang, X. (2015). Binding of (−)-epigallocatechin-3-gallate with thermally-induced bovine serum albumin/i-carrageenan particles. Food Chemistry, 168, 566–571. doi:10.1016/j.foodchem.2014.07.097.
17. Lei, F., Wang, X., Liang, C., Yuan, F., & Gao, Y. (2014). Preparation and functional evaluation of chitosan-EGCG conjugates. Journal of Applied Polymer Science, 131, 1–8. doi:10.1002/app.39732.
18. Chen, Y. C., Yu, S. H., Tsai, G. J., Tang, D. W., Mi, F. L., & Peng, Y. P. (2010). Novel technology for the preparation of self-assembled catechin/gelatin nanoparticles and their characterization. Journal of Agricultural and Food Chemistry, 58, 6728–6734. doi:10.1021/jf1005116.
19. Rajalakshmi, A., Krithiga, N., & Jayachitra, A. (2013). Antioxidant activity of the chitosan extracted from shrimp exoskeleton. Middle- East Journal of Scientific Research, 16, 1446–1451. doi:10.5829/idosi.mejsr.2013.16.10.12033.
20. Norton, A. B., Cox, P. W., & Spyropoulos, F. (2011). Acid gelation of low acyl gellan gum relevant to self-structuring in the human stomach. Food Hydrocolloids, 25, 1105–1111.
21. Jansson, P. E., Lindberg, B., & Sandford, P. A. (1983). Structural studies of gellan gum, an extracellular polysaccharide elaborated by Pseudomonas elodea. Carbohydrate Research, 124, 135–139. doi:10.1016/0008-6215(83)88361-X.
22. Rupenthal, I. D., Green, C. R., & Alany, R. G. (2011). Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 1: physicochemical characterization and in vitro release. International Journal of Pharmacy, 411, 69–77. doi:10.1016/j.ijpharm.2011.03.042.
23. Nayak, A., K., Pal, D., & Santra, K. (2014). Tamarind seed polysaccharide-gellan mucoadhesive beads for controlled release of metformin HCl. Carbohydrate Polymers, 65, 329–339. doi:10.1016/j.carbpol.2013.12.031.
24. Singh, B. N., Trombetta, L. D., & Kim, K. H. (2007). Artocarpus heterophyllus L.seed starch-blended gellan gum mucoadhesive beads of metformin HCL. International Journal of Biological Macromolecules, 341, 143–151.
25. Smith, A. M., Shelton, R. M., Perrie, Y., & Harris, J. J. (2007). An initial evaluation of gellan gum as a material for tissue engineering applications. Journal of Biomaterials Applications, 22(3), 241–254.
26. D’Arrigo, G., Meo, C. D., Gaucci, E., Chichiarelli, S., Coviello, T., Capitani, D., Alhaique, F., & Matricardi, P. (2012). Self-assembled gellan-based nanohydrogels as a tool for prednisolone delivery. Soft Matter, 8, 11557–11564. doi:10.1039/C2SM26178B.
27. Tang, J., Tung, M. A., & Zeng, Y. (1998). Characterization of gellan gels using stress relaxation. Journal of Food Engineering, 38, 279–295. doi:10.1016/S0260-8774(98)00114-9.
28. Kumar, S., Kaur, P., Bernela, M., Rani, R., & Thakur, R. (2016). Ketoconazole encapsulated in chitosan-gellan gum nanocomplexes exhibits prolonged antifungal activity. International Journal of Biological Macromolecules, 93, 988–994. doi:10.1016/j.ijbiomac.2016.09.042.
29. Picone, C. S., & Cunha, R. L. (2013). Chitosan-gellan electrostatic complexes: influence of preparation conditions and surfactant presence. Carbohydrate Polymers, 94, 695–703. doi:10.1016/j.carbpol.2013.01.092.
30. Patil, J. S., Kamalapur, M. V., Marapur, S. C., & Kadam, D. V. (2010). Ionotropic gelation and polyelectrolyte complexation: the novel techniques to design hydrogel particulate sustained, modulated drug delivery system: a review. Digest Journal of Nanomaterials and Biostructures, 5(1), 241–248.
31. Yang, F., Xia, S., Tan, C., & Zhang, X. (2013). Preparation and evaluation of chitosan-calcium-gellan gum beads for controlled release of protein. European Food Research and Technology, 237, 467–479. doi:10.1007/s00217-013-2021-y.
32. Chopra, M., Bernela, M., Kaur, P., Manuja, A., Kumar, B., & Thakur, R. (2015). Alginate/gum acacia bipolymericnanohydrogels—promising carrier for zinc oxide nanoparticles. International Journal of Biological Macromolecules, 72, 827–833. doi:10.1016/j.ijbiomac.2014.09.037.
33. Manuja, A., Kumar, S., Dilbaghi, N., Bhanjana, G., Chopra, M., Kaur, H., Kumar, R., Manuja, B. K., & Yadav, S. C. (2014). Quinpyramine sulfate-loaded sodium alginate nanoparticles shows enhanced trypanocidal activity. Nanomedicine (London), 9, 1625–1634. doi:10.2217/nnm.13.148.
34. Yadav, R., Kumar, D., Kumari, A., & Yadav, S. K. (2014). Encapsulation of catchin and epicatechin on BSA NPs improved their stability and antioxidant potential. EXCLI Journal, 13, 331–346. doi:10.17877/DE290R-15813.
35. Gai, M., Frueh, J., Kudryavtseva, V.L., Mao, R., Kiryukhin, M.V. and Sukhorukov, G.B. (2016). Patterned microstructure fabrication: polyelectrolyte complexes vs polyelectrolyte multilayers. Scientific Reports, 6. doi:10.1038/srep37000.
36. Kaur, H., Ahuja, M., Kumar, S., & Dilbaghi, N. (2012). Carboxymethyl tamarind kernel polysaccharide nanoparticles for ophthalmic drug delivery. International Journal of Biological Macromolecules, 50, 833–839. doi:10.1016/j.ijbiomac.2011.11.017.
37. Dilbaghi, N., Kaur, H., Ahuja, M., & Kumar, S. (2013). Evaluation of tropicamide loaded tamarind seed xyloglucan nanoaggregates for ophthalmic delivery. Carbohydrate Polymers, 94, 286–291. doi:10.1016/j.carbpol.2013.01.054.
38. Ranjan, O. P., Nayak, U. Y., Reddy, M. S., Dengale, S. J., Musmade, P. B., & Udupa, N. (2014). Optimization of Chronomodulated delivery system coated with a blend of ethyl cellulose and eudragit L100 by central composite design: in Vitro and in Vivo evaluation. Journal of Pharmaceutical Innovation, 9, 95–105. doi:10.1007/s12247-014-9176-3.
39. Rani, R., Dilbaghi, N., Dhingra, D., & Kumar, S. (2015). Optimization and evaluation of bioactive drug loaded polymeric nanoparticles for drug delivery. International Journal of Biological Macromolecules, 78, 173–179. doi:10.1016/j.ijbiomac.2015.03.070.
40. Narayana, C. R., Bhandarkar, A., Harish, N. M., & Jobin, J. (2012). Investigation on release profile of chitosan based polyelectrolyte complexes using an antihypertensive agent. International Journal of Pharmaceutical Sciences Review and Research, 15, 88–94.
41. Ponnuraj, R., Janakiraman, K., Gopalakrishnan, S., Meganathan, V., & Saravanan, P. (2015). Formulation and characterization of Epigallocatechin gallate nanoparticles. Indo American. Journal of Pharmaceutical Sciences, 5, 769–779. doi:10.1044/1980-iajpr.150122.
42. Bigucci, F., Luppi, B., Cerchiara, T., Sorrento, M., Bettinetti, G., Rodriguez, L., & Zecchi, V. (2008). Chitosan/pectin polyelectrolyte complexes: selection of suitable preparative conditions for colon-specific delivery of vancomycin. European Journal of Pharmaceutical Sciences, 35, 435–441. doi:10.1016/j.ejps.2008.09.004.
43. Lin, Y. H., Feng, C. L., Lai, C. H., Lin, J. H., & Chen, H. Y. (2014). Preparation of epigallocatechin gallate loaded nanoparticles and characterization of their inhibitory effects on Helicobacter pylori growth in vitro and in vivo. Science and Technology of Advanced Materials, 15, 1–10. doi:10.1088/1468-6996/15/4/045006.
44. Dilbaghi, N., Kaur, H., Ahuja, M., Arora, P., & Kumar, S. (2013). Synthesis and evaluation of ciprofloxacin-loaded carboxymethyl tamarind kernel polysaccharide nanoparticles. Journal of Experimental Nanoscience, 9, 1015–1025. doi:10.1080/17458080.2013.771244.
45. de Souza, J. R. R., de Carvalho, J. I. X., Trevisan, M. T. S., de Paula, R. C. M., Ricardo, N. M. P. S., & Feitosa, J. P. A. (2009). Chitosan-coated pectin beads: characterization and in vitro release of mangiferin. Food Hydrocolloids, 23(8), 2278–2286. doi:10.1016/j.foodhyd.2009.06.004.
46. Bernela, M., Ahuja, M., & Thakur, R. (2016). Enhancement of anti-inflammatory activity of glycyrrhizic acid by encapsulation in chitosan-katira gum nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 105, 141–147. doi:10.1016/j.ejpb.2016.06.003.
47. Rajendran, N., Natrajan, R., Kumar, R., & Selvaraj, S. (2010). Acyclovir-loaded chitosan nanoparticles for ocular delivery. Asian Journal of Pharmaceutical Sciences, 4(4), 220–226. doi:10.4103/0973-8398.76749.
48. Arora, G., Malik, K., Singh, I., Arora, S., & Rana, V. (2011). Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum. Journal of Advanced Pharmaceutical Technology & Research, 2, 163–169. doi:10.4103/2231-4040.85534.
49. Gharib, A., Faezizadeh, Z., & Godarzee, M. (2013). Therapeutic efficacy of Epigallocatechin gallate-loaded nanoliposomes against burn wound infection by methicillin-resistant Staphylococcus aureus. Skin Pharmacology and Physiology, 26(2), 68–75. doi:10.1159/000345761.