Contribution of presystemic hepatic extraction to the low oral bioavailability of green tea catechins in rats

Drug Metabolism and Disposition

Volumn 30, Issue 11, 2002, Pages 1246-1249

  Cai, Yan ^a,b   Anavy, Nathan D ^b   Sherry Chow, H H ^a,b  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHIN; EPICATECHIN; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS;

ANIMAL EXPERIMENT; ARTICLE; CANCER PREVENTION; DISTRIBUTION VOLUME; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INFUSION; DRUG METABOLISM; EXTRACTION; FIRST PASS EFFECT; GASTROINTESTINAL TRACT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE; SYSTEMIC CIRCULATION; TEA; ANIMAL; AREA UNDER THE CURVE; BIOAVAILABILITY; CHEMISTRY; DOSE RESPONSE; INTRAVENOUS DRUG ADMINISTRATION; LIVER; METABOLISM; PORTAL VEIN; WISTAR RAT;

ANIMALIA; RODENTIA; STAPHYLOCOCCUS PHAGE 187;

ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CATECHIN; DOSE-RESPONSE RELATIONSHIP, DRUG; INDICATORS AND REAGENTS; INJECTIONS, INTRAVENOUS; LIVER; MALE; PORTAL VEIN; RATS; RATS, WISTAR; TEA;

EID: 0036842980     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.11.1246     Document Type: Article

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