Broad Targeting Specificity during Bacterial Type III CRISPR-Cas Immunity Constrains Viral Escape

Cell Host and Microbe

Volumn 22, Issue 3, 2017, Pages 343-353.e3

  Pyenson, Nora C ^a   Gayvert, Kaitlyn ^b,c   Varble, Andrew ^a   Elemento, Olivier ^b   Marraffini, Luciano A ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c Tri Institutional Training Program in Computational Biology and Medicine   (United States)

Author keywords

adaptive immunity; bacteria; bacteriophage; Cas; CRISPR; Csm; plasmid conjugation; staphylococcus

Indexed keywords

ARTICLE; BACTERIAL IMMUNITY; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA FLANKING REGION; ESCAPE BEHAVIOR; IMMUNE RESPONSE; NEXT GENERATION SEQUENCING; NONHUMAN; PRIORITY JOURNAL; PYROCOCCUS FURIOSUS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PYOGENES; TERMINAL SEQUENCE; VIRAL ESCAPE; BACTERIOPHAGE; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; PHYSIOLOGY; VIROLOGY;

BACTERIAL PROTEIN;

BACTERIAL PROTEINS; BACTERIOPHAGES; CRISPR-CAS SYSTEMS; HOST-PATHOGEN INTERACTIONS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 85027535502     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.07.016     Document Type: Article

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