-
1
-
-
79952162002
-
Regulation of cellular iron metabolism
-
Wang J, Pantopoulos K. 2011. Regulation of cellular iron metabolism. Biochem J 434:365-381. https://doi.org/10.1042/BJ20101825.
-
(2011)
Biochem J
, vol.434
, pp. 365-381
-
-
Wang, J.1
Pantopoulos, K.2
-
2
-
-
77954249308
-
Two to tango: regulation of mammalian iron metabolism
-
Hentze MW, Muckenthaler MU, Galy B, Camaschella C. 2010. Two to tango: regulation of mammalian iron metabolism. Cell 142:24-38. https://doi.org/10.1016/j.cell.2010.06.028.
-
(2010)
Cell
, vol.142
, pp. 24-38
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Galy, B.3
Camaschella, C.4
-
3
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, Ganz T. 2001. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 276:7806-7810. https://doi.org/10.1074/jbc.M008922200.
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
4
-
-
84864308938
-
Ferroportin-mediated iron transport: expression and regulation
-
Ward DM, Kaplan J. 2012. Ferroportin-mediated iron transport: expression and regulation. Biochim Biophys Acta 1823:1426-1433. https://doi.org/10.1016/j.bbamcr.2012.03.004.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 1426-1433
-
-
Ward, D.M.1
Kaplan, J.2
-
5
-
-
84904768122
-
Iron at the interface of immunity and infection
-
Nairz M, Haschka D, Demetz E, Weiss G. 2014. Iron at the interface of immunity and infection. Front Pharmacol 5:152. https://doi.org/10.3389/fphar.2014.00152.
-
(2014)
Front Pharmacol
, vol.5
, pp. 152
-
-
Nairz, M.1
Haschka, D.2
Demetz, E.3
Weiss, G.4
-
6
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. 2004. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306:2090-2093. https://doi.org/10.1126/science.1104742.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
Ganz, T.7
Kaplan, J.8
-
7
-
-
9444246510
-
Iron and microbial infection
-
Schaible UE, Kaufmann SH. 2004. Iron and microbial infection. Nat Rev Microbiol 2:946-953. https://doi.org/10.1038/nrmicro1046.
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 946-953
-
-
Schaible, U.E.1
Kaufmann, S.H.2
-
8
-
-
33751175421
-
Interleukin-6 induces hepcidin expression through STAT3
-
Wrighting DM, Andrews NC. 2006. Interleukin-6 induces hepcidin expression through STAT3. Blood 108:3204-3209. https://doi.org/10.1182/blood-2006-06-027631.
-
(2006)
Blood
, vol.108
, pp. 3204-3209
-
-
Wrighting, D.M.1
Andrews, N.C.2
-
9
-
-
84920905125
-
Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus
-
Arezes J, Jung G, Gabayan V, Valore E, Ruchala P, Gulig PA, Ganz T, Nemeth E, Bulut Y. 2015. Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus. Cell Host Microbe 17:47-57. https://doi.org/10.1016/j.chom.2014.12.001.
-
(2015)
Cell Host Microbe
, vol.17
, pp. 47-57
-
-
Arezes, J.1
Jung, G.2
Gabayan, V.3
Valore, E.4
Ruchala, P.5
Gulig, P.A.6
Ganz, T.7
Nemeth, E.8
Bulut, Y.9
-
10
-
-
84956625893
-
Helicobacter pylori infection induces anemia, depletes serum iron storage, and alters local ironrelated and adult brain gene expression in male INS-GAS mice
-
Burns M, Muthupalani S, Ge Z, Wang TC, Bakthavatchalu V, Cunningham C, Ennis K, Georgieff M, Fox JG. 2015. Helicobacter pylori infection induces anemia, depletes serum iron storage, and alters local ironrelated and adult brain gene expression in male INS-GAS mice. PLoS One 10:e0142630. https://doi.org/10.1371/journal.pone.0142630.
-
(2015)
PLoS One
, vol.10
-
-
Burns, M.1
Muthupalani, S.2
Ge, Z.3
Wang, T.C.4
Bakthavatchalu, V.5
Cunningham, C.6
Ennis, K.7
Georgieff, M.8
Fox, J.G.9
-
11
-
-
84940737023
-
Hepcidin and host defense against infectious diseases
-
Michels K, Nemeth E, Ganz T, Mehrad B. 2015. Hepcidin and host defense against infectious diseases. PLoS Pathog 11:e1004998. https://doi.org/10.1371/journal.ppat.1004998.
-
(2015)
PLoS Pathog
, vol.11
-
-
Michels, K.1
Nemeth, E.2
Ganz, T.3
Mehrad, B.4
-
12
-
-
80052101945
-
Mycobacteria-induced anaemia revisited: a molecular approach reveals the involvement of NRAMP1 and lipocalin-2, but not of hepcidin
-
Rodrigues PN, Gomes SS, Neves JV, Gomes-Pereira S, Correia-Neves M, Nunes-Alves C, Stolte J, Sanchez M, Appelberg R, Muckenthaler MU, Gomes MS. 2011. Mycobacteria-induced anaemia revisited: a molecular approach reveals the involvement of NRAMP1 and lipocalin-2, but not of hepcidin. Immunobiology 216:1127-1134. https://doi.org/10.1016/j.imbio.2011.04.004.
-
(2011)
Immunobiology
, vol.216
, pp. 1127-1134
-
-
Rodrigues, P.N.1
Gomes, S.S.2
Neves, J.V.3
Gomes-Pereira, S.4
Correia-Neves, M.5
Nunes-Alves, C.6
Stolte, J.7
Sanchez, M.8
Appelberg, R.9
Muckenthaler, M.U.10
Gomes, M.S.11
-
13
-
-
71849112206
-
Listeriosis: a resurgent foodborne infection
-
Allerberger F, Wagner M. 2010. Listeriosis: a resurgent foodborne infection. Clin Microbiol Infect 16:16-23. https://doi.org/10.1111/j.1469-0691.2009.03109.x.
-
(2010)
Clin Microbiol Infect
, vol.16
, pp. 16-23
-
-
Allerberger, F.1
Wagner, M.2
-
14
-
-
17644378780
-
Gastroenteritis due to Listeria monocytogenes
-
Ooi ST, Lorber B. 2005. Gastroenteritis due to Listeria monocytogenes. Clin Infect Dis 40:1327-1332. https://doi.org/10.1086/429324.
-
(2005)
Clin Infect Dis
, vol.40
, pp. 1327-1332
-
-
Ooi, S.T.1
Lorber, B.2
-
15
-
-
84940957656
-
Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens
-
Kortman GA, Mulder ML, Richters TJ, Shanmugam NK, Trebicka E, Boekhorst J, Timmerman HM, Roelofs R, Wiegerinck ET, Laarakkers CM, Swinkels DW, Bolhuis A, Cherayil BJ, Tjalsma H. 2015. Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens. Eur J Immunol 45: 2553-2567. https://doi.org/10.1002/eji.201545642.
-
(2015)
Eur J Immunol
, vol.45
, pp. 2553-2567
-
-
Kortman, G.A.1
Mulder, M.L.2
Richters, T.J.3
Shanmugam, N.K.4
Trebicka, E.5
Boekhorst, J.6
Timmerman, H.M.7
Roelofs, R.8
Wiegerinck, E.T.9
Laarakkers, C.M.10
Swinkels, D.W.11
Bolhuis, A.12
Cherayil, B.J.13
Tjalsma, H.14
-
16
-
-
0034934605
-
Listeria pathogenesis and molecular virulence determinants
-
Vazquez-Boland JA, Kuhn M, Berche P, Chakraborty T, Dominguez-Bernal G, Goebel W, Gonzalez-Zorn B, Wehland J, Kreft J. 2001. Listeria pathogenesis and molecular virulence determinants. Clin Microbiol Rev 14: 584-640. https://doi.org/10.1128/CMR.14.3.584-640.2001.
-
(2001)
Clin Microbiol Rev
, vol.14
, pp. 584-640
-
-
Vazquez-Boland, J.A.1
Kuhn, M.2
Berche, P.3
Chakraborty, T.4
Dominguez-Bernal, G.5
Goebel, W.6
Gonzalez-Zorn, B.7
Wehland, J.8
Kreft, J.9
-
17
-
-
84937974674
-
Understanding the complexities of Salmonellahost crosstalk as revealed by in vivo model organisms
-
Verma S, Srikanth CV. 2015. Understanding the complexities of Salmonellahost crosstalk as revealed by in vivo model organisms. IUBMB Life 67:482-497. https://doi.org/10.1002/iub.1393.
-
(2015)
IUBMB Life
, vol.67
, pp. 482-497
-
-
Verma, S.1
Srikanth, C.V.2
-
18
-
-
84892956031
-
Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6
-
Rodriguez R, Jung CL, Gabayan V, Deng JC, Ganz T, Nemeth E, Bulut Y. 2014. Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6. Infect Immun 82:745-752. https://doi.org/10.1128/IAI.00983-13.
-
(2014)
Infect Immun
, vol.82
, pp. 745-752
-
-
Rodriguez, R.1
Jung, C.L.2
Gabayan, V.3
Deng, J.C.4
Ganz, T.5
Nemeth, E.6
Bulut, Y.7
-
19
-
-
80054114689
-
Hepcidin regulation by innate immune and infectious stimuli
-
Armitage AE, Eddowes LA, Gileadi U, Cole S, Spottiswoode N, Selvakumar TA, Ho LP, Townsend AR, Drakesmith H. 2011. Hepcidin regulation by innate immune and infectious stimuli. Blood 118:4129-4139. https://doi.org/10.1182/blood-2011-04-351957.
-
(2011)
Blood
, vol.118
, pp. 4129-4139
-
-
Armitage, A.E.1
Eddowes, L.A.2
Gileadi, U.3
Cole, S.4
Spottiswoode, N.5
Selvakumar, T.A.6
Ho, L.P.7
Townsend, A.R.8
Drakesmith, H.9
-
20
-
-
33646427702
-
TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens
-
Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V. 2006. TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood 107:3727-3732. https://doi.org/10.1182/blood-2005-06-2259.
-
(2006)
Blood
, vol.107
, pp. 3727-3732
-
-
Peyssonnaux, C.1
Zinkernagel, A.S.2
Datta, V.3
Lauth, X.4
Johnson, R.S.5
Nizet, V.6
-
21
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, Leroyer P, Turlin B, Brissot P, Loreal O. 2001. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 276:7811-7819. https://doi.org/10.1074/jbc.M008923200.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
Leroyer, P.4
Turlin, B.5
Brissot, P.6
Loreal, O.7
-
22
-
-
47949130644
-
Lipopolysaccharide induces a significant increase in expression of iron regulatory hormone hepcidin in the cortex and substantia nigra in rat brain
-
Wang Q, Du F, Qian ZM, Ge XH, Zhu L, Yung WH, Yang L, Ke Y. 2008. Lipopolysaccharide induces a significant increase in expression of iron regulatory hormone hepcidin in the cortex and substantia nigra in rat brain. Endocrinology 149:3920-3925. https://doi.org/10.1210/en.2007-1626.
-
(2008)
Endocrinology
, vol.149
, pp. 3920-3925
-
-
Wang, Q.1
Du, F.2
Qian, Z.M.3
Ge, X.H.4
Zhu, L.5
Yung, W.H.6
Yang, L.7
Ke, Y.8
-
23
-
-
85002662446
-
Regulation of hepcidin expression by inflammation-induced activin B
-
Kanamori Y, Sugiyama M, Hashimoto O, Murakami M, Matsui T, Funaba M. 2016. Regulation of hepcidin expression by inflammation-induced activin B. Sci Rep 6:38702. https://doi.org/10.1038/srep38702.
-
(2016)
Sci Rep
, vol.6
, pp. 38702
-
-
Kanamori, Y.1
Sugiyama, M.2
Hashimoto, O.3
Murakami, M.4
Matsui, T.5
Funaba, M.6
-
24
-
-
79955958017
-
Hepcidin and iron regulation, 10 years later
-
Ganz T. 2011. Hepcidin and iron regulation, 10 years later. Blood 117: 4425-4433. https://doi.org/10.1182/blood-2011-01-258467.
-
(2011)
Blood
, vol.117
, pp. 4425-4433
-
-
Ganz, T.1
-
25
-
-
84892657750
-
The liver: conductor of systemic iron balance
-
Meynard D, Babitt JL, Lin HY. 2014. The liver: conductor of systemic iron balance. Blood 123:168-176. https://doi.org/10.1182/blood-2013-06-427757.
-
(2014)
Blood
, vol.123
, pp. 168-176
-
-
Meynard, D.1
Babitt, J.L.2
Lin, H.Y.3
-
26
-
-
84898042156
-
Inverse agonist of estrogen-related receptor gamma controls Salmonella Typhimurium infection by modulating host iron homeostasis
-
Kim DK, Jeong JH, Lee JM, Kim KS, Park SH, Kim YD, Koh M, Shin M, Jung YS, Kim HS, Lee TH, Oh BC, Kim JI, Park HT, Jeong WI, Lee CH, Park SB, Min JJ, Jung SI, Choi SY, Choy HE, Choi HS. 2014. Inverse agonist of estrogen-related receptor gamma controls Salmonella Typhimurium infection by modulating host iron homeostasis. Nat Med 20:419-424. https://doi.org/10.1038/nm.3483.
-
(2014)
Nat Med
, vol.20
, pp. 419-424
-
-
Kim, D.K.1
Jeong, J.H.2
Lee, J.M.3
Kim, K.S.4
Park, S.H.5
Kim, Y.D.6
Koh, M.7
Shin, M.8
Jung, Y.S.9
Kim, H.S.10
Lee, T.H.11
Oh, B.C.12
Kim, J.I.13
Park, H.T.14
Jeong, W.I.15
Lee, C.H.16
Park, S.B.17
Min, J.J.18
Jung, S.I.19
Choi, S.Y.20
Choy, H.E.21
Choi, H.S.22
more..
-
27
-
-
85012931830
-
ERRgamma: a junior orphan with a senior role in metabolism
-
Misra J, Kim DK, Choi HS. 2017. ERRgamma: a junior orphan with a senior role in metabolism. Trends Endocrinol Metab 28:261-272. https://doi.org/10.1016/j.tem.2016.12.005.
-
(2017)
Trends Endocrinol Metab
, vol.28
, pp. 261-272
-
-
Misra, J.1
Kim, D.K.2
Choi, H.S.3
-
28
-
-
84876539389
-
Role of hepcidin in the setting of hypoferremia during acute inflammation
-
Deschemin JC, Vaulont S. 2013. Role of hepcidin in the setting of hypoferremia during acute inflammation. PLoS One 8:e61050. https://doi.org/10.1371/journal.pone.0061050.
-
(2013)
PLoS One
, vol.8
-
-
Deschemin, J.C.1
Vaulont, S.2
-
29
-
-
84926660351
-
A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia
-
Guida C, Altamura S, Klein FA, Galy B, Boutros M, Ulmer AJ, Hentze MW, Muckenthaler MU. 2015. A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia. Blood 125:2265-2275. https://doi.org/10.1182/blood-2014-08-595256.
-
(2015)
Blood
, vol.125
, pp. 2265-2275
-
-
Guida, C.1
Altamura, S.2
Klein, F.A.3
Galy, B.4
Boutros, M.5
Ulmer, A.J.6
Hentze, M.W.7
Muckenthaler, M.U.8
-
30
-
-
84879426573
-
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection
-
Silva-Gomes S, Appelberg R, Larsen R, Soares MP, Gomes MS. 2013. Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection. Infect Immun 81:2536-2545. https://doi.org/10.1128/IAI.00251-13.
-
(2013)
Infect Immun
, vol.81
, pp. 2536-2545
-
-
Silva-Gomes, S.1
Appelberg, R.2
Larsen, R.3
Soares, M.P.4
Gomes, M.S.5
-
31
-
-
84944411374
-
Heme as a danger molecule in pathogen recognition
-
Wegiel B, Hauser CJ, Otterbein LE. 2015. Heme as a danger molecule in pathogen recognition. Free Radic Biol Med 89:651-661. https://doi.org/10.1016/j.freeradbiomed.2015.08.020.
-
(2015)
Free Radic Biol Med
, vol.89
, pp. 651-661
-
-
Wegiel, B.1
Hauser, C.J.2
Otterbein, L.E.3
-
32
-
-
84879571563
-
Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection
-
Nairz M, Schleicher U, Schroll A, Sonnweber T, Theurl I, Ludwiczek S, Talasz H, Brandacher G, Moser PL, Muckenthaler MU, Fang FC, Bogdan C, Weiss G. 2013. Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection. J Exp Med 210:855-873. https://doi.org/10.1084/jem.20121946.
-
(2013)
J Exp Med
, vol.210
, pp. 855-873
-
-
Nairz, M.1
Schleicher, U.2
Schroll, A.3
Sonnweber, T.4
Theurl, I.5
Ludwiczek, S.6
Talasz, H.7
Brandacher, G.8
Moser, P.L.9
Muckenthaler, M.U.10
Fang, F.C.11
Bogdan, C.12
Weiss, G.13
-
33
-
-
84929484406
-
Increased ferroportin-1 expression and rapid splenic iron loss occur with anemia caused by Salmonella enterica serovar Typhimurium infection in mice
-
Brown DE, Nick HJ, McCoy MW, Moreland SM, Stepanek AM, Benik R, O'Connell KE, Pilonieta MC, Nagy TA, Detweiler CS. 2015. Increased ferroportin-1 expression and rapid splenic iron loss occur with anemia caused by Salmonella enterica serovar Typhimurium infection in mice. Infect Immun 83:2290-2299. https://doi.org/10.1128/IAI.02863-14.
-
(2015)
Infect Immun
, vol.83
, pp. 2290-2299
-
-
Brown, D.E.1
Nick, H.J.2
McCoy, M.W.3
Moreland, S.M.4
Stepanek, A.M.5
Benik, R.6
O'Connell, K.E.7
Pilonieta, M.C.8
Nagy, T.A.9
Detweiler, C.S.10
-
34
-
-
85021691926
-
Iron-and hepcidin-independent downregulation of the iron exporter ferroportin in macrophages during Salmonella infection
-
Willemetz A, Beatty S, Richer E, Rubio A, Auriac A, Milkereit RJ, Thibaudeau O, Vaulont S, Malo D, Canonne-Hergaux F. 2017. Iron-and hepcidin-independent downregulation of the iron exporter ferroportin in macrophages during Salmonella infection. Front Immunol 8:498. https://doi.org/10.3389/fimmu.2017.00498.
-
(2017)
Front Immunol
, vol.8
, pp. 498
-
-
Willemetz, A.1
Beatty, S.2
Richer, E.3
Rubio, A.4
Auriac, A.5
Milkereit, R.J.6
Thibaudeau, O.7
Vaulont, S.8
Malo, D.9
Canonne-Hergaux, F.10
-
35
-
-
21544449756
-
Regulation of hepcidin and ferroportin expression by lipopolysaccharide in splenic macrophages
-
Liu XB, Nguyen NB, Marquess KD, Yang F, Haile DJ. 2005. Regulation of hepcidin and ferroportin expression by lipopolysaccharide in splenic macrophages. Blood Cells Mol Dis 35:47-56. https://doi.org/10.1016/j.bcmd.2005.04.006.
-
(2005)
Blood Cells Mol Dis
, vol.35
, pp. 47-56
-
-
Liu, X.B.1
Nguyen, N.B.2
Marquess, K.D.3
Yang, F.4
Haile, D.J.5
-
36
-
-
0002413872
-
Tissue iron stores
-
Cook JD (eds.) Churchill Livingstone Press, New York, NY
-
Torrance JD, Bothwell TH. 1980. Tissue iron stores, p 104-109. In Cook JD (ed), Methods in hematology, vol 1. Churchill Livingstone Press, New York, NY.
-
(1980)
Methods in hematology
, vol.1
, pp. 104-109
-
-
Torrance, J.D.1
Bothwell, T.H.2
|