Author Correction: Efficient increase of ɣ-aminobutyric acid (GABA) content in tomato fruits by targeted mutagenesis (Scientific Reports, (2017), 7, 1, (7057), 10.1038/s41598-017-06400-y);Efficient increase of Γ-aminobutyric acid (GABA) content in tomato fruits by targeted mutagenesis

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Nonaka, Satoko ^a   Arai, Chikako ^a   Takayama, Mariko ^a   Matsukura, Chiaki ^a   Ezura, Hiroshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; GLUTAMATE DECARBOXYLASE 2;

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; ENZYMOLOGY; FRUIT; GENE DELETION; GENE EDITING; GENETICS; METABOLIC ENGINEERING; METABOLISM; MUTAGENESIS; PROCEDURES; TOMATO;

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEIN 9; FRUIT; GAMMA-AMINOBUTYRIC ACID; GENE EDITING; GLUTAMATE DECARBOXYLASE; LYCOPERSICON ESCULENTUM; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; MUTAGENESIS; SEQUENCE DELETION;

EID: 85026761649     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-019-55119-5     Document Type: Erratum

References (48)

1. NCD Risk Factor Collaboration (NCD-RisC) Worldwide trends in blood pressure from 1975 to 2015: A pooled analysis of 1479 population-based measurement studies with 191 million participants. The Lancet 389, 37-55 (2017).
2. Takahashi, H., Tiba, M., Iino, M. & Takayasu, T. The effect of-aminobutyric acid on blood pressure. Jpn. J. Physiol. 5, 334-341 (1995).
3. Takahashi, H., Sumi, M. & Koshino, F. Effect of gamma-aminobutyric acid (GABA) on normotensive or hypertensive rats and men. Jpn. J. Physiol. 11, 89-95 (1961).
4. Elliott, K. A. C. & Hobbiger, F. Gamma aminobutyric acid: circulatory and respiratory effects in different species; re-investigation of the anti-strychnine action in mice. J. Physiol. 146, 70-84 (1959).
5. Tsushida, T. & Murai, T. Conversion of glutamic acid to-aminobutyric acid in tea leaves under anaerobic conditions. Agric. Biol. Chem. 51, 2865-2871 (1987).
6. Saikusa, T., Horino, T. & Mori, Y. Distribution of free amino acids in the rice kernel and kernel fractions and the effect of water soaking on the distribution. J Agric Food Chem. 42, 1122-1125 (1994).
7. Aoki, H. et al. The production of a new tempeh-like fermented soybean containing a high level of gamma-aminobutyric acid by anaerobic incubation with Rhizopus. Biosci Biotechnol Biochem. 67, 1018-23 (2003).
8. Park, K. B. & Oh, S. H. Production of yogurt with enhanced levels of gamma-aminobutyric acid and valuable nutrients using lactic acid bacteria and germinated soybean extract. Bioresour Technol. 98, 1675-1679 (2007).
9. Yamakoshi, J. et al. Antihypertensive and natriuretic effects of less-sodium soy sauce containing-aminobutyric acid in spontaneously hypertensive rats. Biosci. Biotechnol. Biochem. 71, 165-173 (2007).
10. Omori, M. et al. Effect of anaerobically treated tea (Gabaron tea) on blood pressure of spontaneously hypertensive rats. Nippon Nogeikagaku Kaishi (in Japanese) 61, 1449-1451 (1987).
11. Inoue, K. et al. Blood-pressure-lowering effect of a novel fermented milk containing-aminobutyric acid (GABA) in mild hypertensives. Eur. J. Clin. Nutr. 57, 490-495 (2003).
12. Matsumoto, Y., Ohno, K. & Hiraoka, Y. Studies on the utilization of functional food materials containing high levels of gammaaminobutyric acid (Part 1). Ehime Kougi Kenkyu Houkoku 35, 97-100 (1997). (in Japanese).
13. Rolin, D. et al. NMR study of low subcellular pH during the development of cherry tomato fruit. Aust. J. Plant Physiol. 27, 61-69 (2000).
14. Koike, S., Matsukura, C., Takayama, M., Asamizu, M. & Ezura, H. Suppression of-aminobutyric acid (GABA) transaminases induces prominent GABA accumulation, dwarfism and infertility in the tomato (Solanum lycopersicum L.). Plant Cell Physiol. 54, 793-807 (2013).
15. Saito, T. et al. TOMATOMA: A novel tomato mutant database distributing Micro-Tom mutant collections. Plant Cell Physiol. 52, 283-296 (2011).
16. Bouché, N. & Fromm, H. GABA in plants: just a metabolite Trends Plant Sci. 9, 110-115 (2004).
17. Akihiro, T. et al. Biochemical mechanism on GABA accumulation during fruit development in tomato. Plant Cell Physiol. 49, 1378-1389 (2008).
18. Takayama, M. et al. Tomato glutamate decarboxylase genes SlGAD2 and SlGAD3 play key roles in regulating-aminobutyric acid levels in tomato (Solanum lycopersicum). Plant Cell Physiol. 56, 1533-1545 (2015).
19. Takayama, M., Matsukura, C., Ariizumi, T. & Ezura, H. Activating glutamate decarboxylase activity by removing the autoinhibitory domain leads to hyper-aminobutyric acid (GABA) accumulation in tomato fruit. Plant Cell Rep. 36, 103-116 (2017).
20. Gut, H. et al. A common structural basis for pH-and calmodulin-mediated regulation in plant decarboxylase. J. Mol. Biol. 392, 334-351 (2009).
21. Baum, G. et al. Calmodulin binding to glutamate decarboxylase is required for regulation of glutamate and GABA metabolism and normal development in plants. EMBO J. 15, 2988-2996 (1996).
22. Akama, K. & Takaiwa, F. C-terminal extension of rice glutamate decarboxylase (OsGAD2) functions as an autoinhibitory domain and overexpression of a truncated mutant results in the accumulation of extremely high levels of GABA in plant cells. J. Exp. Bot. 58, 2699-2707 (2007).
23. Fait, A. et al. Targeted enhancement of glutamate-to-aminobutyrate conversion in Arabidopsis seeds affects carbon-nitrogen balance and storage reserves in a development-dependent manner. Plant Physiol. 157, 1026-1042 (2011).
24. Okabe, Y. et al. Tomato TILLING technology: development of a reverse genetics tool for the efficient isolation of mutants from Micro-Tom mutant libraries. Plant Cell Physiol. 52, 1994-2005 (2011).
25. Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
26. Chang, N. et al. Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos. Cell Res. 23, 465-472 (2013).
27. Bassett, A. R., Tibbit, C., Ponting, C. P. & Liu, J. L. Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. Cell Rep. 11, 220-228 (2013).
28. Jiang, W. et al. Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice. Nucleic Acids Res. 41, e188 (2013).
29. Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821 (2012).
30. Brooks, C., Nekrasov, V., Lippman, Z. B. & Van Eck, J. Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated9 system. Plant Physiol. 166, 1292-1297 (2014).
31. Ito, Y., Nishizawa-Yokoi, A., Endo, M., Mikami, M. & Toki, S. CRISPR/Cas9-mediated mutagenesis of the RIN locus that regulates tomato fruit ripening. Biochem. Biophys. Res. Commun. 467, 76-82 (2015).
32. Pan, C. et al. CRISPR/Cas9-mediated efficient and heritable targeted mutagenesis in tomato plants in the first and later generations. Sci. Rep. 6, 24765 (2016).
33. Sun, H. J., Uchii, S., Watanabe, S. & Ezura, H. A highly efficient transformation protocol for Micro-Tom, a model cultivar for tomato functional genomics. Plant Cell Physiol. 47, 426-431 (2006).
34. Zhang, H. et al. The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation. Plant Biotechnol J. 12, 797-807 (2014).
35. Renault, H. et al. GABA accumulation causes cell elongation defects and a decrease in expression of genes encoding secreted and cell wall-related proteins in Arabidopsis thaliana. Plant Cell Physiol. 52, 894-908 (2011).
36. Trobacher, C. P. et al. Calmodulin-dependent and calmodulin-independent glutamate decarboxylase in apple fruit. BMC Plant Biol. 13, 144 (2013).
37. Baum, G., Chen, Y., Arazi, T., Takatsuji, H. & Fromm, H. plant glutamate decarboxylase containing a calmodulin binding domain. Cloning, sequence, and functional analysis. J Biol Chem. 268, 19610-19617 (1993).
38. Bown, A. W. & Shelp, B. J. The metabolism and functions of-aminobutyric acid. Plant Physiol. 115, 1-5 (1997).
39. Fukuwatari, Y. et al. A study on the antihypertensive action and safety of tablets containing-aminobutyric acid (GABA). Eastern Med. 17, 1-7 (2001). (in Japanese).
40. Kazami, D. et al. Antihypertensive effect of Japanese taste seasoning containing-amino butyric acid on mildly hypertensive and high-normal blood pressure subjects and normal subjects. Nippon Shokuhin Kagaku Kogaku Kaishi 49, 409-415 (2002). (in Japanese).
41. Zik, M., Fridmann-Sirkis, Y. & Fromm, H. C-terminal residues of plant glutamate decarboxylase are required for oligomerization of a high-molecular weight complex and for activation by calcium/calmodulin. Biochim Biophys Acta. 1764, 872-876 (2006).
42. Yuan, T. & Vogel, H. J. Calcium-calmodulin-induced dimerization of the carboxyl-terminal domain from petunia glutamate decarboxylase. A novel calmodulin-peptide interaction motif. J. Biol. Chem. 273, 30328-30335 (1998).
43. Yap, K. L., Yuan, T., Mal, T. K., Vogel, H. J. & Ikura, M. Structural basis for simultaneous binding of two carboxy-terminal peptides of plant glutamate decarboxylase to calmodulin. J. Mol. Biol. 328, 193-204 (2003).
44. Fauser, F., Schiml, S. & Puchta, H. Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana. Plant J. 79, 348-359 (2014).
45. Mikami, M., Toki, S. & Endo, M. Comparison of CRISPR/Cas9 expression constructs for efficient targeted mutagenesis in rice. Plant Mol. Biol. 88, 561-571 (2015).
46. Deblaere, R. et al. Efficient octopine Ti plasmid-derived vectors for Agrobacterium-mediated gene transfer to plants. Nucleic. Acids. Res. 13, 4777-4788 (1985).
47. Jakoby, W. B. Enzymes of-aminobutyrate metabolism (Bacterial). Methods Enzymol. 5, 765-778 (1962).
48. Arazi, T., Baum, G., Snedden, W. A., Shelp, B. J. & Fromm, H. Molecular and biochemical analysis of calmodulin interactions with the calmodulin-binding domain of plant glutamate decarboxylase. Plant Physiol. 108, 551-561 (1995).