Exogenous administration of mitochondrial DNA promotes ischemia reperfusion injury via TLR9-p38 MAPK pathway

Regulatory Toxicology and Pharmacology

Volumn 89, Issue , 2017, Pages 148-154

  Xie, Liang ^a   Liu, Shuyu ^a   Cheng, Jinghua ^a   Wang, Lijun ^a   Liu, Jing ^a   Gong, Jianbin ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

H9c2; Mitochondrial DNA; p38 MAPK; TLR9

Indexed keywords

CASPASE 3; CELL NUCLEUS DNA; CHLOROQUINE; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 9; ANTIMALARIAL AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME ACTIVITY; H9C2 CELL LINE; HEART INFARCTION SIZE; MALE; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; TOXICITY; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENETICS; HEART INFARCTION; METABOLISM; PHOSPHORYLATION;

ANIMALS; ANTIMALARIALS; CASPASE 3; CELL LINE; CHLOROQUINE; DNA, MITOCHONDRIAL; IN SITU NICK-END LABELING; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; REPERFUSION INJURY; TOLL-LIKE RECEPTOR 9;

EID: 85026480409     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2017.07.028     Document Type: Article

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