Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

International Journal of Molecular Medicine

Volumn 33, Issue 5, 2014, Pages 1097-1109

  Sun, Zhaorui ^a,b,c   Wang, Cong ^a,b,c   Shi, Chaowen ^a,b,c   Sun, Fangfang ^a,b,c   Xu, Xiaomeng ^a,b,c   Qian, Weiping ^b   Nie, Shinan ^a   Han, Xiaodong ^a,b,c  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b SOUTHEAST UNIVERSITY   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

Lung injury; Mesenchymal stem cells; Pulmonary fibrosis; Stromal cell derived factor 1 CXC chemokine receptor 4; Wnt catenin signaling

Indexed keywords

5' NUCLEOTIDASE; ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; BETA1 INTEGRIN; CHEMOKINE RECEPTOR CXCR4; COLLAGEN TYPE 1; DICKKOPF 1 PROTEIN; HERMES ANTIGEN; STROMAL CELL DERIVED FACTOR 1; THY 1 ANTIGEN; VIMENTIN; WNT PROTEIN; HYDROCHLORIC ACID;

ADENOVIRUS; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENGRAFTMENT; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; MALE; MESENCHYMAL STEM CELL; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL MOBILIZATION; WNT SIGNALING PATHWAY; ANIMAL; CYTOLOGY; DRUG EFFECTS; MESENCHYMAL STROMA CELL; METABOLISM; PULMONARY FIBROSIS; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TOXICITY;

ANIMALS; CELL DIFFERENTIATION; HYDROCHLORIC ACID; MALE; MESENCHYMAL STROMAL CELLS; MYOFIBROBLASTS; PULMONARY FIBROSIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 84899530769     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1672     Document Type: Article

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