메뉴 건너뛰기




Volumn 2, Issue 11, 2016, Pages

KDM5 lysine demethylases are involved in maintenance of 3′UTR length

(17)  Blair, Lauren P a,f   Liu, Zongzhi a   Labitigan, Ramon Lorenzo D a,g   Wu, Lizhen a   Zheng, Dinghai b   Xia, Zheng c,h   Pearson, Erica L d   Nazeer, Fathima I d,i   Cao, Jian a   Lang, Sabine M a   Rines, Rachel J a,j   Mackintosh, Samuel G e   Moore, Claire L d   Li, Wei c   Tian, Bin b   Tackett, Alan J e   Yan, Qin a  


Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GENES; MACHINERY; MAMMALS; NUCLEIC ACIDS; TRANSCRIPTION; YEAST;

EID: 85026398015     PISSN: None     EISSN: 23752548     Source Type: Journal    
DOI: 10.1126/sciadv.1501662     Document Type: Article
Times cited : (24)

References (76)
  • 1
    • 84859893371 scopus 로고    scopus 로고
    • Histone methylation: A dynamic mark in health, disease and inheritance
    • E. L. Greer, Y. Shi, Histone methylation: A dynamic mark in health, disease and inheritance. Nat. Rev. Genet. 13, 343-357 (2012).
    • (2012) Nat. Rev. Genet , vol.13 , pp. 343-357
    • Greer, E.L.1    Shi, Y.2
  • 5
    • 65249123408 scopus 로고    scopus 로고
    • Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression
    • D. P. Mersman, H.-N. Du, I. M. Fingerman, P. F. South, S. D. Briggs, Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression. Genes Dev. 23, 951-962 (2009).
    • (2009) Genes Dev , vol.23 , pp. 951-962
    • Mersman, D.P.1    Du, H.-N.2    Fingerman, I.M.3    South, P.F.4    Briggs, S.D.5
  • 6
    • 84883062782 scopus 로고    scopus 로고
    • Genome-wide mapping of polyadenylation sites in fission yeast reveals widespread alternative polyadenylation
    • J. Mata, Genome-wide mapping of polyadenylation sites in fission yeast reveals widespread alternative polyadenylation. RNA Biol. 10, 1407-1414 (2013).
    • (2013) RNA Biol , vol.10 , pp. 1407-1414
    • Mata, J.1
  • 8
    • 84869765539 scopus 로고    scopus 로고
    • Alternative polyadenylation: New insights from global analyses
    • Y. Shi, Alternative polyadenylation: New insights from global analyses. RNA 18, 2105-2117 (2012).
    • (2012) RNA , vol.18 , pp. 2105-2117
    • Shi, Y.1
  • 9
    • 84874311599 scopus 로고    scopus 로고
    • Genome-wide maps of polyadenylation reveal dynamic mRNA 3′-end formation in mammalian cell lineages
    • L. Wang, R. D. Dowell, R. Yi, Genome-wide maps of polyadenylation reveal dynamic mRNA 3′-end formation in mammalian cell lineages. RNA 19, 413-425 (2013).
    • (2013) RNA , vol.19 , pp. 413-425
    • Wang, L.1    Dowell, R.D.2    Yi, R.3
  • 11
    • 84879408529 scopus 로고    scopus 로고
    • Alternative cleavage and polyadenylation: Extent, regulation and function
    • R. Elkon, A. P. Ugalde, R. Agami, Alternative cleavage and polyadenylation: Extent, regulation and function. Nat. Rev. Genet. 14, 496-506 (2013).
    • (2013) Nat. Rev. Genet , vol.14 , pp. 496-506
    • Elkon, R.1    Ugalde, A.P.2    Agami, R.3
  • 12
    • 84878151459 scopus 로고    scopus 로고
    • Alternative cleavage and polyadenylation: The long and short of it
    • B. Tian, J. L. Manley, Alternative cleavage and polyadenylation: The long and short of it. Trends Biochem. Sci. 38, 312-320 (2013).
    • (2013) Trends Biochem. Sci , vol.38 , pp. 312-320
    • Tian, B.1    Manley, J.L.2
  • 13
    • 77953284100 scopus 로고    scopus 로고
    • Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation
    • S. Millevoi, S. Vagner, Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation. Nucleic Acids Res. 38, 2757-2774 (2010).
    • (2010) Nucleic Acids Res , vol.38 , pp. 2757-2774
    • Millevoi, S.1    Vagner, S.2
  • 14
    • 33751090746 scopus 로고    scopus 로고
    • Phosphorylation and functions of the RNA polymerase II CTD
    • H. P. Phatnani, A. L. Greenleaf, Phosphorylation and functions of the RNA polymerase II CTD. Genes Dev. 20, 2922-2936 (2006).
    • (2006) Genes Dev , vol.20 , pp. 2922-2936
    • Phatnani, H.P.1    Greenleaf, A.L.2
  • 15
    • 58649121693 scopus 로고    scopus 로고
    • Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3′ end processing factor Pcf11
    • S. A. Johnson, G. Cubberley, D. L. Bentley, Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3′ end processing factor Pcf11. Mol. Cell 33, 215-226 (2009).
    • (2009) Mol. Cell , vol.33 , pp. 215-226
    • Johnson, S.A.1    Cubberley, G.2    Bentley, D.L.3
  • 17
    • 77955291830 scopus 로고    scopus 로고
    • The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation
    • F. Huang, M. B. Chandrasekharan, Y.-C. Chen, S. Bhaskara, S. W. Hiebert, Z.-W. Sun, The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation. J. Biol. Chem. 285, 24548-24561 (2010).
    • (2010) J. Biol. Chem , vol.285 , pp. 24548-24561
    • Huang, F.1    Chandrasekharan, M.B.2    Chen, Y.-C.3    Bhaskara, S.4    Hiebert, S.W.5    Sun, Z.-W.6
  • 18
    • 84884623321 scopus 로고    scopus 로고
    • A role for CF1A 3′ end processing complex in promoterassociated transcription
    • N. Al Husini, P. Kudla, A. Ansari, A role for CF1A 3′ end processing complex in promoterassociated transcription. PLOS Genet. 9, e1003722 (2013).
    • (2013) PLOS Genet , vol.9 , pp. e1003722
    • Al Husini, N.1    Kudla, P.2    Ansari, A.3
  • 21
    • 1542290655 scopus 로고    scopus 로고
    • Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes
    • M. Kim, S.-H. Ahn, N. J. Krogan, J. F. Greenblatt, S. Buratowski, Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes. EMBO J. 23, 354-364 (2004).
    • (2004) EMBO J , vol.23 , pp. 354-364
    • Kim, M.1    Ahn, S.-H.2    Krogan, N.J.3    Greenblatt, J.F.4    Buratowski, S.5
  • 22
    • 0031024993 scopus 로고    scopus 로고
    • PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor i
    • N. Amrani, M. Minet, F. Wyers, M. E. Dufour, L. P. Aggerbeck, F. Lacroute, PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I. Mol. Cell. Biol. 17, 1102-1109 (1997).
    • (1997) Mol. Cell. Biol , vol.17 , pp. 1102-1109
    • Amrani, N.1    Minet, M.2    Wyers, F.3    Dufour, M.E.4    Aggerbeck, L.P.5    Lacroute, F.6
  • 23
    • 0038219583 scopus 로고    scopus 로고
    • Independent functions of yeast Pcf11p in pre-mRNA 3′ end processing and in transcription termination
    • M. Sadowski, B. Dichtl, W. Hübner, W. Keller, Independent functions of yeast Pcf11p in pre-mRNA 3′ end processing and in transcription termination. EMBO J. 22, 2167-2177 (2003).
    • (2003) EMBO J , vol.22 , pp. 2167-2177
    • Sadowski, M.1    Dichtl, B.2    Hübner, W.3    Keller, W.4
  • 25
    • 69249221216 scopus 로고    scopus 로고
    • Involvement of Pta1 Pcf11 and a KlCYC1 AU-rich element in alternative RNA 3′-end processing selection in yeast
    • S. Seoane, M. Lamas-Maceiras, A. M. Rodríguez-Torres, M. A. Freire-Picos, Involvement of Pta1, Pcf11 and a KlCYC1 AU-rich element in alternative RNA 3′-end processing selection in yeast. FEBS Lett. 583, 2843-2848 (2009).
    • (2009) FEBS Lett , vol.583 , pp. 2843-2848
    • Seoane, S.1    Lamas-Maceiras, M.2    Rodríguez-Torres, A.M.3    Freire-Picos, M.A.4
  • 26
    • 84873405541 scopus 로고    scopus 로고
    • Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing
    • M. Hoque, Z. Ji, D. Zheng, W. Luo, W. Li, B. You, J. Yeon Park, G. Yehia, B. Tian, Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing. Nat. Methods 10, 133-139 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 133-139
    • Hoque, M.1    Ji, Z.2    Zheng, D.3    Luo, W.4    Li, W.5    You, B.6    Yeon Park, J.7    Yehia, G.8    Tian, B.9
  • 27
    • 78649910014 scopus 로고    scopus 로고
    • Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation
    • F. Ozsolak, P. Kapranov, S. Foissac, S. W. Kim, E. Fishilevich, A. P. Monaghan, B. John, P. M. Milos, Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation. Cell 143, 1018-1029 (2010).
    • (2010) Cell , vol.143 , pp. 1018-1029
    • Ozsolak, F.1    Kapranov, P.2    Foissac, S.3    Kim, S.W.4    Fishilevich, E.5    Monaghan, A.P.6    John, B.7    Milos, P.M.8
  • 29
    • 79953708822 scopus 로고    scopus 로고
    • Epigenetic regulation by lysine demethylase 5 (KDM5) enzymes in cancer
    • L. P. Blair, J. Cao, M. R. Zou, J. Sayegh, Q. Yan, Epigenetic regulation by lysine demethylase 5 (KDM5) enzymes in cancer. Cancers (Basel) 3, 1383 (2011).
    • (2011) Cancers (Basel) , vol.3 , pp. 1383
    • Blair, L.P.1    Cao, J.2    Zou, M.R.3    Sayegh, J.4    Yan, Q.5
  • 32
    • 49349092791 scopus 로고    scopus 로고
    • The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation
    • B. K. Dey, L. Stalker, A. Schnerch, M. Bhatia, J. Taylor-Papidimitriou, C. Wynder, The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation. Mol. Cell. Biol. 28, 5312-5327 (2008).
    • (2008) Mol. Cell. Biol , vol.28 , pp. 5312-5327
    • Dey, B.K.1    Stalker, L.2    Schnerch, A.3    Bhatia, M.4    Taylor-Papidimitriou, J.5    Wynder, C.6
  • 33
    • 79955008193 scopus 로고    scopus 로고
    • KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription
    • L. Xie, C. Pelz, W. Wang, A. Bashar, O. Varlamova, S. Shadle, S. Impey, KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J. 30, 1473-1484 (2011).
    • (2011) EMBO J , vol.30 , pp. 1473-1484
    • Xie, L.1    Pelz, C.2    Wang, W.3    Bashar, A.4    Varlamova, O.5    Shadle, S.6    Impey, S.7
  • 37
    • 84903482610 scopus 로고    scopus 로고
    • Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes
    • M. R. Zou, J. Cao, Z. Liu, S. J. Huh, K. Polyak, Q. Yan, Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J. Biol. Chem. 289, 17620-17633 (2014).
    • (2014) J. Biol. Chem , vol.289 , pp. 17620-17633
    • Zou, M.R.1    Cao, J.2    Liu, Z.3    Huh, S.J.4    Polyak, K.5    Yan, Q.6
  • 44
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • C. Mayr, D. P. Bartel, Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138, 673-684 (2009).
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 45
    • 84870581925 scopus 로고    scopus 로고
    • Estrogen-induced upregulation and 3′-UTR shortening of CDC6
    • B. H. Akman, T. Can, A. E. Erson-Bensan, Estrogen-induced upregulation and 3′-UTR shortening of CDC6. Nucleic Acids Res. 40, 10679-16088 (2012).
    • (2012) Nucleic Acids Res , vol.40 , pp. 10679-16088
    • Akman, B.H.1    Can, T.2    Erson-Bensan, A.E.3
  • 46
    • 84856710408 scopus 로고    scopus 로고
    • Shortening of 3′UTRs correlates with poor prognosis in breast and lung cancer
    • A. Lembo, F. Di Cunto, P. Provero, Shortening of 3′UTRs correlates with poor prognosis in breast and lung cancer. PLOS ONE 7, e31129 (2012).
    • (2012) PLOS ONE , vol.7 , pp. e31129
    • Lembo, A.1    Di Cunto, F.2    Provero, P.3
  • 47
    • 84923366707 scopus 로고    scopus 로고
    • Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types
    • Z. Xia, L. A. Donehower, T. A. Cooper, J. R. Neilson, D. A. Wheeler, E. J. Wagner, W. Li, Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types. Nat. Commun. 5, 5274 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 5274
    • Xia, Z.1    Donehower, L.A.2    Cooper, T.A.3    Neilson, J.R.4    Wheeler, D.A.5    Wagner, E.J.6    Li, W.7
  • 51
    • 84994888055 scopus 로고    scopus 로고
    • An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting
    • J. Cao, L. Wu, S.-M. Zhang, M. Lu, W. K. C. Cheung, W. Cai, M. Gale, Q. Xu, Q. Yan, An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting. Nucleic Acids Res. gkw660 (2016).
    • (2016) Nucleic Acids Res. , pp. gkw660
    • Cao, J.1    Wu, L.2    Zhang, S.-M.3    Lu, M.4    Cheung, W.K.C.5    Cai, W.6    Gale, M.7    Xu, Q.8    Yan, Q.9
  • 52
    • 84982914036 scopus 로고    scopus 로고
    • Screenidentified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance
    • M. Gale, J. Sayegh, J. Cao, M. Norcia, P. Gareiss, D. Hoyer, J. S. Merkel, Q. Yan, Screenidentified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget 7, 39931-39944 (2016).
    • (2016) Oncotarget , vol.7 , pp. 39931-39944
    • Gale, M.1    Sayegh, J.2    Cao, J.3    Norcia, M.4    Gareiss, P.5    Hoyer, D.6    Merkel, J.S.7    Yan, Q.8
  • 53
    • 0027215176 scopus 로고
    • 3′ RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes
    • G. Edwalds-Gilbert, J. Prescott, E. Falck-Pedersen, 3′ RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes. Mol. Cell. Biol. 13, 3472-3480 (1993).
    • (1993) Mol. Cell. Biol , vol.13 , pp. 3472-3480
    • Edwalds-Gilbert, G.1    Prescott, J.2    Falck-Pedersen, E.3
  • 54
    • 16244422640 scopus 로고    scopus 로고
    • Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Gg-globin gene
    • K. E. Plant, M. J. Dye, C. Lafaille, N. J. Proudfoot, Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Gg-globin gene. Mol. Cell. Biol. 25, 3276-3285 (2005).
    • (2005) Mol. Cell. Biol , vol.25 , pp. 3276-3285
    • Plant, K.E.1    Dye, M.J.2    Lafaille, C.3    Proudfoot, N.J.4
  • 55
    • 0034679725 scopus 로고    scopus 로고
    • Transcriptional termination and coupled polyadenylation in vitro
    • M. Yonaha, N. J. Proudfoot, Transcriptional termination and coupled polyadenylation in vitro. EMBO J. 19, 3770-3777 (2000).
    • (2000) EMBO J , vol.19 , pp. 3770-3777
    • Yonaha, M.1    Proudfoot, N.J.2
  • 57
    • 4043129097 scopus 로고    scopus 로고
    • Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors
    • M. C. Yu, F. Bachand, A. E. McBride, S. Komili, J. M. Casolari, P. A. Silver, Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors. Genes Dev. 18, 2024-2035 (2004).
    • (2004) Genes Dev , vol.18 , pp. 2024-2035
    • Yu, M.C.1    Bachand, F.2    McBride, A.E.3    Komili, S.4    Casolari, J.M.5    Silver, P.A.6
  • 58
  • 59
    • 84881113123 scopus 로고    scopus 로고
    • Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome
    • M. Bremang, A. Cuomo, A. M. Agresta, M. Stugiewicz, V. Spadotto, T. Bonaldi, Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome. Mol. Biosyst. 9, 2231-2247 (2013).
    • (2013) Mol. Biosyst , vol.9 , pp. 2231-2247
    • Bremang, M.1    Cuomo, A.2    Agresta, A.M.3    Stugiewicz, M.4    Spadotto, V.5    Bonaldi, T.6
  • 62
    • 84908339823 scopus 로고    scopus 로고
    • KDM5 interacts with Foxo to modulate cellular levels of oxidative stress
    • X. Liu, C. Greer, J. Secombe, KDM5 interacts with Foxo to modulate cellular levels of oxidative stress. PLOS Genet. 10, e1004676 (2014).
    • (2014) PLOS Genet , vol.10 , pp. e1004676
    • Liu, X.1    Greer, C.2    Secombe, J.3
  • 63
    • 84875987260 scopus 로고    scopus 로고
    • Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen
    • J. Sayegh, J. Cao, M. R. Zou, A. Morales, L. P. Blair, M. Norcia, D. Hoyer, A. J. Tackett, J. S. Merkel, Q. Yan, Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J. Biol. Chem. 288, 9408-9417 (2013).
    • (2013) J. Biol. Chem , vol.288 , pp. 9408-9417
    • Sayegh, J.1    Cao, J.2    Zou, M.R.3    Morales, A.4    Blair, L.P.5    Norcia, M.6    Hoyer, D.7    Tackett, A.J.8    Merkel, J.S.9    Yan, Q.10
  • 65
    • 84861182365 scopus 로고    scopus 로고
    • Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2, 4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor
    • L. H. Kristensen, A. L. Nielsen, C. Helgstrand, M. Lees, P. Cloos, J. S. Kastrup, K. Helin, L. Olsen, M. Gajhede, Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2, 4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. FEBS J. 279, 1905-1914 (2012).
    • (2012) FEBS J , vol.279 , pp. 1905-1914
    • Kristensen, L.H.1    Nielsen, A.L.2    Helgstrand, C.3    Lees, M.4    Cloos, P.5    Kastrup, J.S.6    Helin, K.7    Olsen, L.8    Gajhede, M.9
  • 68
    • 0032721092 scopus 로고    scopus 로고
    • Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor
    • J. Zhao, M. Kessler, S. Helmling, J. P. O'Connor, C. Moore, Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol. Cell. Biol. 19, 7733-7740 (1999).
    • (1999) Mol. Cell. Biol , vol.19 , pp. 7733-7740
    • Zhao, J.1    Kessler, M.2    Helmling, S.3    O'Connor, J.P.4    Moore, C.5
  • 69
    • 84919770754 scopus 로고    scopus 로고
    • The evolutionarily conserved Pol II flap loop contributes to proper transcription termination on short yeast genes
    • E. Pearson, C. Moore, The evolutionarily conserved Pol II flap loop contributes to proper transcription termination on short yeast genes. Cell Rep. 9, 821-828 (2014).
    • (2014) Cell Rep , vol.9 , pp. 821-828
    • Pearson, E.1    Moore, C.2
  • 71
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • B. Langmead, S. L. Salzberg, Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357-359 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 72
    • 84905049901 scopus 로고    scopus 로고
    • Trimmomatic: A flexible trimmer for Illumina sequence data
    • A. M. Bolger, M. Lohse, B. Usadel, Trimmomatic: A flexible trimmer for Illumina sequence data. Bioinformatics 30, 2114-2120 (2014).
    • (2014) Bioinformatics , vol.30 , pp. 2114-2120
    • Bolger, A.M.1    Lohse, M.2    Usadel, B.3
  • 73
    • 67650711619 scopus 로고    scopus 로고
    • A clustering approach for identification of enriched domains from histone modification ChIP-Seq data
    • C. Zang, D. E. Schones, C. Zeng, K. Cui, K. Zhao, W. Peng, A clustering approach for identification of enriched domains from histone modification ChIP-Seq data. Bioinformatics 25, 1952-1958 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1952-1958
    • Zang, C.1    Schones, D.E.2    Zeng, C.3    Cui, K.4    Zhao, K.5    Peng, W.6
  • 74
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • S. Heinz, C. Benner, N. Spann, E. Bertolino, Y. C. Lin, P. Laslo, J. X. Cheng, C. Murre, H. Singh, C. K. Glass, Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 576
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5    Laslo, P.6    Cheng, J.X.7    Murre, C.8    Singh, H.9    Glass, C.K.10
  • 76
    • 68349098404 scopus 로고    scopus 로고
    • RNA immunoprecipitation to determine RNA-protein associations in vivo
    • pdb.prot5234
    • L. A. Selth, C. Gilbert, J. Q. Svejstrup, RNA immunoprecipitation to determine RNA-protein associations in vivo. Cold Spring Harb. Protoc. pdb.prot5234 (2009).
    • (2009) Cold Spring Harb. Protoc.
    • Selth, L.A.1    Gilbert, C.2    Svejstrup, J.Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.