-
1
-
-
84859893371
-
Histone methylation: A dynamic mark in health, disease and inheritance
-
E. L. Greer, Y. Shi, Histone methylation: A dynamic mark in health, disease and inheritance. Nat. Rev. Genet. 13, 343-357 (2012).
-
(2012)
Nat. Rev. Genet
, vol.13
, pp. 343-357
-
-
Greer, E.L.1
Shi, Y.2
-
2
-
-
33847660838
-
Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase
-
G. Liang, R. J. Klose, K. E. Gardner, Y. Zhang, Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Nat. Struct. Mol. Biol. 14, 243-245 (2007).
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 243-245
-
-
Liang, G.1
Klose, R.J.2
Gardner, K.E.3
Zhang, Y.4
-
3
-
-
33847613217
-
Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins
-
D. J. Seward, G. Cubberley, S. Kim, M. Schonewald, L. Zhang, B. Tripet, D. L. Bentley, Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins. Nat. Struct. Mol. Biol. 14, 240-242 (2007).
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 240-242
-
-
Seward, D.J.1
Cubberley, G.2
Kim, S.3
Schonewald, M.4
Zhang, L.5
Tripet, B.6
Bentley, D.L.7
-
4
-
-
34347207597
-
Identification of histone demethylases in Saccharomyces cerevisiae
-
S. Tu, E. M. M. Bulloch, L. Yang, C. Ren, W.-C. Huang, P.-H. Hsu, C.-H. Chen, C.-L. Liao, H.-M. Yu, W.-S. Lo, M. A. Freitas, M.-D. Tsai, Identification of histone demethylases in Saccharomyces cerevisiae. J. Biol. Chem. 282, 14262-14271 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 14262-14271
-
-
Tu, S.1
Bulloch, E.M.M.2
Yang, L.3
Ren, C.4
Huang, W.-C.5
Hsu, P.-H.6
Chen, C.-H.7
Liao, C.-L.8
Yu, H.-M.9
Lo, W.-S.10
Freitas, M.A.11
Tsai, M.-D.12
-
5
-
-
65249123408
-
Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression
-
D. P. Mersman, H.-N. Du, I. M. Fingerman, P. F. South, S. D. Briggs, Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression. Genes Dev. 23, 951-962 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 951-962
-
-
Mersman, D.P.1
Du, H.-N.2
Fingerman, I.M.3
South, P.F.4
Briggs, S.D.5
-
6
-
-
84883062782
-
Genome-wide mapping of polyadenylation sites in fission yeast reveals widespread alternative polyadenylation
-
J. Mata, Genome-wide mapping of polyadenylation sites in fission yeast reveals widespread alternative polyadenylation. RNA Biol. 10, 1407-1414 (2013).
-
(2013)
RNA Biol
, vol.10
, pp. 1407-1414
-
-
Mata, J.1
-
7
-
-
84866910243
-
An in-depth map of polyadenylation sites in cancer
-
Y. Lin, Z. Li, F. Ozsolak, S. Woo Kim, G. Arango-Argoty, T. T. Liu, S. A. Tenenbaum, T. Bailey, A. Paula Monaghan, P. M. Milos, B. John, An in-depth map of polyadenylation sites in cancer. Nucleic Acids Res. 40, 8460-8471 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 8460-8471
-
-
Lin, Y.1
Li, Z.2
Ozsolak, F.3
Woo Kim, S.4
Arango-Argoty, G.5
Liu, T.T.6
Tenenbaum, S.A.7
Bailey, T.8
Paula Monaghan, A.9
Milos, P.M.10
John, B.11
-
8
-
-
84869765539
-
Alternative polyadenylation: New insights from global analyses
-
Y. Shi, Alternative polyadenylation: New insights from global analyses. RNA 18, 2105-2117 (2012).
-
(2012)
RNA
, vol.18
, pp. 2105-2117
-
-
Shi, Y.1
-
9
-
-
84874311599
-
Genome-wide maps of polyadenylation reveal dynamic mRNA 3′-end formation in mammalian cell lineages
-
L. Wang, R. D. Dowell, R. Yi, Genome-wide maps of polyadenylation reveal dynamic mRNA 3′-end formation in mammalian cell lineages. RNA 19, 413-425 (2013).
-
(2013)
RNA
, vol.19
, pp. 413-425
-
-
Wang, L.1
Dowell, R.D.2
Yi, R.3
-
10
-
-
84863230221
-
Alternative polyadenylation mediates microRNA regulation of muscle stem cell function
-
S. C. Boutet, T. H. Cheung, N. L. Quach, L. Liu, S. L. Prescott, A. Edalati, K. Iori, T. A. Rando, Alternative polyadenylation mediates microRNA regulation of muscle stem cell function. Cell Stem Cell 10, 327-336 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 327-336
-
-
Boutet, S.C.1
Cheung, T.H.2
Quach, N.L.3
Liu, L.4
Prescott, S.L.5
Edalati, A.6
Iori, K.7
Rando, T.A.8
-
11
-
-
84879408529
-
Alternative cleavage and polyadenylation: Extent, regulation and function
-
R. Elkon, A. P. Ugalde, R. Agami, Alternative cleavage and polyadenylation: Extent, regulation and function. Nat. Rev. Genet. 14, 496-506 (2013).
-
(2013)
Nat. Rev. Genet
, vol.14
, pp. 496-506
-
-
Elkon, R.1
Ugalde, A.P.2
Agami, R.3
-
12
-
-
84878151459
-
Alternative cleavage and polyadenylation: The long and short of it
-
B. Tian, J. L. Manley, Alternative cleavage and polyadenylation: The long and short of it. Trends Biochem. Sci. 38, 312-320 (2013).
-
(2013)
Trends Biochem. Sci
, vol.38
, pp. 312-320
-
-
Tian, B.1
Manley, J.L.2
-
13
-
-
77953284100
-
Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation
-
S. Millevoi, S. Vagner, Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation. Nucleic Acids Res. 38, 2757-2774 (2010).
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 2757-2774
-
-
Millevoi, S.1
Vagner, S.2
-
14
-
-
33751090746
-
Phosphorylation and functions of the RNA polymerase II CTD
-
H. P. Phatnani, A. L. Greenleaf, Phosphorylation and functions of the RNA polymerase II CTD. Genes Dev. 20, 2922-2936 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 2922-2936
-
-
Phatnani, H.P.1
Greenleaf, A.L.2
-
15
-
-
58649121693
-
Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3′ end processing factor Pcf11
-
S. A. Johnson, G. Cubberley, D. L. Bentley, Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3′ end processing factor Pcf11. Mol. Cell 33, 215-226 (2009).
-
(2009)
Mol. Cell
, vol.33
, pp. 215-226
-
-
Johnson, S.A.1
Cubberley, G.2
Bentley, D.L.3
-
16
-
-
80455177038
-
The export factor Yra1 modulates mRNA 3′ end processing
-
S. A. Johnson, H. Kim, B. Erickson, D. L. Bentley, The export factor Yra1 modulates mRNA 3′ end processing. Nat. Struct. Mol. Biol. 18, 1164-1471 (2011).
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 1164-1471
-
-
Johnson, S.A.1
Kim, H.2
Erickson, B.3
Bentley, D.L.4
-
17
-
-
77955291830
-
The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation
-
F. Huang, M. B. Chandrasekharan, Y.-C. Chen, S. Bhaskara, S. W. Hiebert, Z.-W. Sun, The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation. J. Biol. Chem. 285, 24548-24561 (2010).
-
(2010)
J. Biol. Chem
, vol.285
, pp. 24548-24561
-
-
Huang, F.1
Chandrasekharan, M.B.2
Chen, Y.-C.3
Bhaskara, S.4
Hiebert, S.W.5
Sun, Z.-W.6
-
18
-
-
84884623321
-
A role for CF1A 3′ end processing complex in promoterassociated transcription
-
N. Al Husini, P. Kudla, A. Ansari, A role for CF1A 3′ end processing complex in promoterassociated transcription. PLOS Genet. 9, e1003722 (2013).
-
(2013)
PLOS Genet
, vol.9
, pp. e1003722
-
-
Al Husini, N.1
Kudla, P.2
Ansari, A.3
-
19
-
-
84859969858
-
The spt5 C-terminal region recruits yeast 3′ RNA cleavage factor i
-
A. Mayer, A. Schreieck, M. Lidschreiber, K. Leike, D. E. Martin, P. Cramer, The spt5 C-terminal region recruits yeast 3′ RNA cleavage factor I. Mol. Cell. Biol. 32, 1321-1331 (2012).
-
(2012)
Mol. Cell. Biol
, vol.32
, pp. 1321-1331
-
-
Mayer, A.1
Schreieck, A.2
Lidschreiber, M.3
Leike, K.4
Martin, D.E.5
Cramer, P.6
-
20
-
-
84856845697
-
An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination
-
R. Haddad, F. Maurice, N. Viphakone, F. Voisinet-Hakil, S. Fribourg, L. Minvielle-Sébastia, An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination. Nucleic Acids Res. 40, 1226-1239 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1226-1239
-
-
Haddad, R.1
Maurice, F.2
Viphakone, N.3
Voisinet-Hakil, F.4
Fribourg, S.5
Minvielle-Sébastia, L.6
-
21
-
-
1542290655
-
Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes
-
M. Kim, S.-H. Ahn, N. J. Krogan, J. F. Greenblatt, S. Buratowski, Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes. EMBO J. 23, 354-364 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 354-364
-
-
Kim, M.1
Ahn, S.-H.2
Krogan, N.J.3
Greenblatt, J.F.4
Buratowski, S.5
-
22
-
-
0031024993
-
PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor i
-
N. Amrani, M. Minet, F. Wyers, M. E. Dufour, L. P. Aggerbeck, F. Lacroute, PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I. Mol. Cell. Biol. 17, 1102-1109 (1997).
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 1102-1109
-
-
Amrani, N.1
Minet, M.2
Wyers, F.3
Dufour, M.E.4
Aggerbeck, L.P.5
Lacroute, F.6
-
23
-
-
0038219583
-
Independent functions of yeast Pcf11p in pre-mRNA 3′ end processing and in transcription termination
-
M. Sadowski, B. Dichtl, W. Hübner, W. Keller, Independent functions of yeast Pcf11p in pre-mRNA 3′ end processing and in transcription termination. EMBO J. 22, 2167-2177 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 2167-2177
-
-
Sadowski, M.1
Dichtl, B.2
Hübner, W.3
Keller, W.4
-
24
-
-
0034740637
-
The KlCYC1 gene, a downstream region for two differentially regulated transcripts
-
M. A. Freire-Picos, L. J. Lombardia-Ferreira, E. Ramil, M. González-Domínguez, M. E. Cerdan, The KlCYC1 gene, a downstream region for two differentially regulated transcripts. Yeast 18, 1347-1355 (2001).
-
(2001)
Yeast
, vol.18
, pp. 1347-1355
-
-
Freire-Picos, M.A.1
Lombardia-Ferreira, L.J.2
Ramil, E.3
González-Domínguez, M.4
Cerdan, M.E.5
-
25
-
-
69249221216
-
Involvement of Pta1 Pcf11 and a KlCYC1 AU-rich element in alternative RNA 3′-end processing selection in yeast
-
S. Seoane, M. Lamas-Maceiras, A. M. Rodríguez-Torres, M. A. Freire-Picos, Involvement of Pta1, Pcf11 and a KlCYC1 AU-rich element in alternative RNA 3′-end processing selection in yeast. FEBS Lett. 583, 2843-2848 (2009).
-
(2009)
FEBS Lett
, vol.583
, pp. 2843-2848
-
-
Seoane, S.1
Lamas-Maceiras, M.2
Rodríguez-Torres, A.M.3
Freire-Picos, M.A.4
-
26
-
-
84873405541
-
Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing
-
M. Hoque, Z. Ji, D. Zheng, W. Luo, W. Li, B. You, J. Yeon Park, G. Yehia, B. Tian, Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing. Nat. Methods 10, 133-139 (2013).
-
(2013)
Nat. Methods
, vol.10
, pp. 133-139
-
-
Hoque, M.1
Ji, Z.2
Zheng, D.3
Luo, W.4
Li, W.5
You, B.6
Yeon Park, J.7
Yehia, G.8
Tian, B.9
-
27
-
-
78649910014
-
Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation
-
F. Ozsolak, P. Kapranov, S. Foissac, S. W. Kim, E. Fishilevich, A. P. Monaghan, B. John, P. M. Milos, Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation. Cell 143, 1018-1029 (2010).
-
(2010)
Cell
, vol.143
, pp. 1018-1029
-
-
Ozsolak, F.1
Kapranov, P.2
Foissac, S.3
Kim, S.W.4
Fishilevich, E.5
Monaghan, A.P.6
John, B.7
Milos, P.M.8
-
28
-
-
84885078620
-
DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast
-
J. H. Graber, F. I. Nazeer, P.-c. Yeh, J. N. Kuehner, S. Borikar, D. Hoskinson, C. L. Moore, DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast. Genome Res. 23, 1690-1703 (2013).
-
(2013)
Genome Res
, vol.23
, pp. 1690-1703
-
-
Graber, J.H.1
Nazeer, F.I.2
Yeh, P.-C.3
Kuehner, J.N.4
Borikar, S.5
Hoskinson, D.6
Moore, C.L.7
-
29
-
-
79953708822
-
Epigenetic regulation by lysine demethylase 5 (KDM5) enzymes in cancer
-
L. P. Blair, J. Cao, M. R. Zou, J. Sayegh, Q. Yan, Epigenetic regulation by lysine demethylase 5 (KDM5) enzymes in cancer. Cancers (Basel) 3, 1383 (2011).
-
(2011)
Cancers (Basel)
, vol.3
, pp. 1383
-
-
Blair, L.P.1
Cao, J.2
Zou, M.R.3
Sayegh, J.4
Yan, Q.5
-
30
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
S. V. Sharma, D. Y. Lee, B. Li, M. P. Quinlan, F. Takahashi, S. Maheswaran, U. McDermott, N. Azizian, L. Zou, M. A. Fischbach, K.-K. Wong, K. Brandstetter, B. Wittner, S. Ramaswamy, M. Classon, J. Settleman, A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 141, 69-80 (2010).
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
Maheswaran, S.6
McDermott, U.7
Azizian, N.8
Zou, L.9
Fischbach, M.A.10
Wong, K.-K.11
Brandstetter, K.12
Wittner, B.13
Ramaswamy, S.14
Classon, M.15
Settleman, J.16
-
31
-
-
80051998696
-
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
-
W. Lin, J. Cao, J. Liu, M. L. Beshiri, Y. Fujiwara, J. Francis, A. D. Cherniack, C. Geisen, L. P. Blair, M. R. Zou, X. Shen, D. Kawamori, Z. Liu, C. Grisanzio, H. Watanabe, Y. A. Minamishima, Q. Zhang, R. N. Kulkarni, S. Signoretti, S. J. Rodig, R. T. Bronson, S. H. Orkin, D. P. Tuck, E. V. Benevolenskaya, M. Meyerson, W. G. Kaeli, Q. Yan, Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1. Proc. Natl. Acad. Sci. U.S.A. 108, 13379-13386 (2011).
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 13379-13386
-
-
Lin, W.1
Cao, J.2
Liu, J.3
Beshiri, M.L.4
Fujiwara, Y.5
Francis, J.6
Cherniack, A.D.7
Geisen, C.8
Blair, L.P.9
Zou, M.R.10
Shen, X.11
Kawamori, D.12
Liu, Z.13
Grisanzio, C.14
Watanabe, H.15
Minamishima, Y.A.16
Zhang, Q.17
Kulkarni, R.N.18
Signoretti, S.19
Rodig, S.J.20
Bronson, R.T.21
Orkin, S.H.22
Tuck, D.P.23
Benevolenskaya, E.V.24
Meyerson, M.25
Kaeli, W.G.26
Yan, Q.27
more..
-
32
-
-
49349092791
-
The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation
-
B. K. Dey, L. Stalker, A. Schnerch, M. Bhatia, J. Taylor-Papidimitriou, C. Wynder, The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation. Mol. Cell. Biol. 28, 5312-5327 (2008).
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 5312-5327
-
-
Dey, B.K.1
Stalker, L.2
Schnerch, A.3
Bhatia, M.4
Taylor-Papidimitriou, J.5
Wynder, C.6
-
33
-
-
79955008193
-
KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription
-
L. Xie, C. Pelz, W. Wang, A. Bashar, O. Varlamova, S. Shadle, S. Impey, KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J. 30, 1473-1484 (2011).
-
(2011)
EMBO J
, vol.30
, pp. 1473-1484
-
-
Xie, L.1
Pelz, C.2
Wang, W.3
Bashar, A.4
Varlamova, O.5
Shadle, S.6
Impey, S.7
-
34
-
-
81255160602
-
Jarid1b targets genes regulating development and is involved in neural differentiation
-
S. U. Schmitz, M. Albert, M. Malatesta, L. Morey, J. V Johansen, M. Bak, N. Tommerup, I. Abarrategui, K. Helin, Jarid1b targets genes regulating development and is involved in neural differentiation. EMBO J. 30, 4586-4600 (2011).
-
(2011)
EMBO J
, vol.30
, pp. 4586-4600
-
-
Schmitz, S.U.1
Albert, M.2
Malatesta, M.3
Morey, L.4
Johansen, J.V.5
Bak, M.6
Tommerup, N.7
Abarrategui, I.8
Helin, K.9
-
35
-
-
37649023563
-
JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer
-
Y. Xiang, Z. Zhu, G. Han, X. Ye, B. Xu, Z. Peng, Y. Ma, Y. Yu, H. Lin, A. P. Chen, C. D. Chen, JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc. Natl. Acad. Sci. U.S.A. 104, 19226-19231 (2007).
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 19226-19231
-
-
Xiang, Y.1
Zhu, Z.2
Han, G.3
Ye, X.4
Xu, B.5
Peng, Z.6
Ma, Y.7
Yu, Y.8
Lin, H.9
Chen, A.P.10
Chen, C.D.11
-
36
-
-
84895921477
-
Histone demethylase RBP2 is critical for breast cancer progression and metastasis
-
J. Cao, Z. Liu, W. K. C. Cheung, M. Zhao, S. Y. Chen, S. W. Chan, C. J. Booth, D. X. Nguyen, Q. Yan, Histone demethylase RBP2 is critical for breast cancer progression and metastasis. Cell Rep. 6, 868-877 (2014).
-
(2014)
Cell Rep
, vol.6
, pp. 868-877
-
-
Cao, J.1
Liu, Z.2
Cheung, W.K.C.3
Zhao, M.4
Chen, S.Y.5
Chan, S.W.6
Booth, C.J.7
Nguyen, D.X.8
Yan, Q.9
-
37
-
-
84903482610
-
Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes
-
M. R. Zou, J. Cao, Z. Liu, S. J. Huh, K. Polyak, Q. Yan, Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J. Biol. Chem. 289, 17620-17633 (2014).
-
(2014)
J. Biol. Chem
, vol.289
, pp. 17620-17633
-
-
Zou, M.R.1
Cao, J.2
Liu, Z.3
Huh, S.J.4
Polyak, K.5
Yan, Q.6
-
38
-
-
84881425351
-
Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis
-
Y.-C. Teng, C.-F. Lee, Y.-S. Li, Y.-R. Chen, P.-W. Hsiao, M.-Y. Chan, F.-M. Lin, H.-D. Huang, Y.-T. Chen, Y.-M. Jeng, C.-H. Hsu, Q. Yan, M.-D. Tsai, L.-J. Juan, Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis. Cancer Res. 73, 4711-4721 (2013).
-
(2013)
Cancer Res
, vol.73
, pp. 4711-4721
-
-
Teng, Y.-C.1
Lee, C.-F.2
Li, Y.-S.3
Chen, Y.-R.4
Hsiao, P.-W.5
Chan, M.-Y.6
Lin, F.-M.7
Huang, H.-D.8
Chen, Y.-T.9
Jeng, Y.-M.10
Hsu, C.-H.11
Yan, Q.12
Tsai, M.-D.13
Juan, L.-J.14
-
39
-
-
0038748632
-
A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically upregulated in breast cancer
-
P. J. Lu, K. Sundquist, D. Baeckstrom, R. Poulsom, A. Hanby, S. Meier-Ewert, T. Jones, M. Mitchell, P. Pitha-Rowe, P. Freemont, J. Taylor-Papadimitriou, A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically upregulated in breast cancer. J. Biol. Chem. 274, 15633-15645 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 15633-15645
-
-
Lu, P.J.1
Sundquist, K.2
Baeckstrom, D.3
Poulsom, R.4
Hanby, A.5
Meier-Ewert, S.6
Jones, T.7
Mitchell, M.8
Pitha-Rowe, P.9
Freemont, P.10
Taylor-Papadimitriou, J.11
-
40
-
-
79955019522
-
PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells
-
S. Catchpole, B. Spencer-Dene, D. Hall, S. Santangelo, I. Rosewell, M. Guenatri, R. Beatson, A. G. Scibetta, J. M. Burchell, J. Taylor-Papadimitriou, PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells. Int. J. Oncol. 38, 1267-1277 (2011).
-
(2011)
Int. J. Oncol
, vol.38
, pp. 1267-1277
-
-
Catchpole, S.1
Spencer-Dene, B.2
Hall, D.3
Santangelo, S.4
Rosewell, I.5
Guenatri, M.6
Beatson, R.7
Scibetta, A.G.8
Burchell, J.M.9
Taylor-Papadimitriou, J.10
-
41
-
-
84902520020
-
JARID1B is a luminal lineage-driving oncogene in breast cancer
-
S. Yamamoto, Z. Wu, H. G. Russnes, S. Takagi, G. Peluffo, C. Vaske, X. Zhao, H. K. M. Vollan, R. Maruyama, M. B. Ekram, H. Sun, J. H. Kim, K. Carver, M. Zucca, J. Feng, V. Almendro, M. Bessarabova, O. M. Rueda, Y. Nikolsky, C. Caldas, X. S. Liu, K. Polyak, JARID1B is a luminal lineage-driving oncogene in breast cancer. Cancer Cell 25, 762-777 (2014).
-
(2014)
Cancer Cell
, vol.25
, pp. 762-777
-
-
Yamamoto, S.1
Wu, Z.2
Russnes, H.G.3
Takagi, S.4
Peluffo, G.5
Vaske, C.6
Zhao, X.7
Vollan, H.K.M.8
Maruyama, R.9
Ekram, M.B.10
Sun, H.11
Kim, J.H.12
Carver, K.13
Zucca, M.14
Feng, J.15
Almendro, V.16
Bessarabova, M.17
Rueda, O.M.18
Nikolsky, Y.19
Caldas, C.20
Liu, X.S.21
Polyak, K.22
more..
-
42
-
-
77952502408
-
A temporarily distinct subpopulation of slowcycling melanoma cells is required for continuous tumor growth
-
A. Roesch, M. Fukunaga-Kalabis, E. C. Schmidt, S. E. Zabierowski, P. A. Brafford, A. Vultur, D. Basu, P. Gimotty, T. Vogt, M. Herlyn, A temporarily distinct subpopulation of slowcycling melanoma cells is required for continuous tumor growth. Cell 141, 583-594 (2010).
-
(2010)
Cell
, vol.141
, pp. 583-594
-
-
Roesch, A.1
Fukunaga-Kalabis, M.2
Schmidt, E.C.3
Zabierowski, S.E.4
Brafford, P.A.5
Vultur, A.6
Basu, D.7
Gimotty, P.8
Vogt, T.9
Herlyn, M.10
-
43
-
-
84878959237
-
Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1Bhigh cells
-
A. Roesch, A. Vultur, I. Bogeski, H. Wang, K. M. Zimmermann, D. Speicher, C. Körbel, M. W. Laschke, P. A. Gimotty, S. E. Philipp, E. Krause, S. Pätzold, J. Villanueva, C. Krepler, M. Fukunaga-Kalabis, M. Hoth, B. C. Bastian, T. Vogt, M. Herlyn, Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1Bhigh cells. Cancer Cell 23, 811-825 (2013).
-
(2013)
Cancer Cell
, vol.23
, pp. 811-825
-
-
Roesch, A.1
Vultur, A.2
Bogeski, I.3
Wang, H.4
Zimmermann, K.M.5
Speicher, D.6
Körbel, C.7
Laschke, M.W.8
Gimotty, P.A.9
Philipp, S.E.10
Krause, E.11
Pätzold, S.12
Villanueva, J.13
Krepler, C.14
Fukunaga-Kalabis, M.15
Hoth, M.16
Bastian, B.C.17
Vogt, T.18
Herlyn, M.19
-
44
-
-
68749113985
-
Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
-
C. Mayr, D. P. Bartel, Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138, 673-684 (2009).
-
(2009)
Cell
, vol.138
, pp. 673-684
-
-
Mayr, C.1
Bartel, D.P.2
-
45
-
-
84870581925
-
Estrogen-induced upregulation and 3′-UTR shortening of CDC6
-
B. H. Akman, T. Can, A. E. Erson-Bensan, Estrogen-induced upregulation and 3′-UTR shortening of CDC6. Nucleic Acids Res. 40, 10679-16088 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 10679-16088
-
-
Akman, B.H.1
Can, T.2
Erson-Bensan, A.E.3
-
46
-
-
84856710408
-
Shortening of 3′UTRs correlates with poor prognosis in breast and lung cancer
-
A. Lembo, F. Di Cunto, P. Provero, Shortening of 3′UTRs correlates with poor prognosis in breast and lung cancer. PLOS ONE 7, e31129 (2012).
-
(2012)
PLOS ONE
, vol.7
, pp. e31129
-
-
Lembo, A.1
Di Cunto, F.2
Provero, P.3
-
47
-
-
84923366707
-
Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types
-
Z. Xia, L. A. Donehower, T. A. Cooper, J. R. Neilson, D. A. Wheeler, E. J. Wagner, W. Li, Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types. Nat. Commun. 5, 5274 (2014).
-
(2014)
Nat. Commun
, vol.5
, pp. 5274
-
-
Xia, Z.1
Donehower, L.A.2
Cooper, T.A.3
Neilson, J.R.4
Wheeler, D.A.5
Wagner, E.J.6
Li, W.7
-
48
-
-
84978719250
-
Structural basis for KDM5A histone lysine demethylase inhibition by diverse compounds
-
J. R. Horton, X. Liu, M. Gale, L. Wu, J. R. Shanks, X. Zhang, P. J. Webber, J. S.K. Bell, S. C. Kales, B. T. Mott, G. Rai, D. J. Jansen, M. J. Henderson, D. J. Urban, M. D. Hall, A. Simeonov, D. J. Maloney, M. A. Johns, H. Fu, A. Jadhav, P. M. Vertino, Q. Yan, X. Cheng, Structural basis for KDM5A histone lysine demethylase inhibition by diverse compounds. Cell Chem. Biol. 23, 769-781 (2016).
-
(2016)
Cell Chem. Biol
, vol.23
, pp. 769-781
-
-
Horton, J.R.1
Liu, X.2
Gale, M.3
Wu, L.4
Shanks, J.R.5
Zhang, X.6
Webber, P.J.7
Bell, J.S.K.8
Kales, S.C.9
Mott, B.T.10
Rai, G.11
Jansen, D.J.12
Henderson, M.J.13
Urban, D.J.14
Hall, M.D.15
Simeonov, A.16
Maloney, D.J.17
Johns, M.A.18
Fu, H.19
Jadhav, A.20
Vertino, P.M.21
Yan, Q.22
Cheng, X.23
more..
-
49
-
-
84969902813
-
Structural analysis of human KDM5B guides histone demethylase inhibitor development
-
C. Johansson, S. Velupillai, A. Tumber, A. Szykowska, E. S. Hookway, R. P. Nowak, C. Strain-Damerell, C. Gileadi, M. Philpott, N. Burgess-Brown, N. Wu, J. Kopec, A. Nuzzi, H. Steuber, U. Egner, V. Badock, S. Munro, N. B. LaThangue, S. Westaway, J. Brown, N. Athanasou, R. Prinjha, P. E. Brennan, U. Oppermann, Structural analysis of human KDM5B guides histone demethylase inhibitor development. Nat. Chem. Biol. 12, 539-545 (2016).
-
(2016)
Nat. Chem. Biol
, vol.12
, pp. 539-545
-
-
Johansson, C.1
Velupillai, S.2
Tumber, A.3
Szykowska, A.4
Hookway, E.S.5
Nowak, R.P.6
Strain-Damerell, C.7
Gileadi, C.8
Philpott, M.9
Burgess-Brown, N.10
Wu, N.11
Kopec, J.12
Nuzzi, A.13
Steuber, H.14
Egner, U.15
Badock, V.16
Munro, S.17
LaThangue, N.B.18
Westaway, S.19
Brown, J.20
Athanasou, N.21
Prinjha, R.22
Brennan, P.E.23
Oppermann, U.24
more..
-
50
-
-
84903129276
-
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression
-
C. P. Masamha, Z. Xia, J. Yang, T. R. Albrecht, M. Li, A.-B. Shyu, W. Li, E. J. Wagner, CFIm25 links alternative polyadenylation to glioblastoma tumour suppression. Nature 510, 412-416 (2014).
-
(2014)
Nature
, vol.510
, pp. 412-416
-
-
Masamha, C.P.1
Xia, Z.2
Yang, J.3
Albrecht, T.R.4
Li, M.5
Shyu, A.-B.6
Li, W.7
Wagner, E.J.8
-
51
-
-
84994888055
-
An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting
-
J. Cao, L. Wu, S.-M. Zhang, M. Lu, W. K. C. Cheung, W. Cai, M. Gale, Q. Xu, Q. Yan, An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting. Nucleic Acids Res. gkw660 (2016).
-
(2016)
Nucleic Acids Res.
, pp. gkw660
-
-
Cao, J.1
Wu, L.2
Zhang, S.-M.3
Lu, M.4
Cheung, W.K.C.5
Cai, W.6
Gale, M.7
Xu, Q.8
Yan, Q.9
-
52
-
-
84982914036
-
Screenidentified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance
-
M. Gale, J. Sayegh, J. Cao, M. Norcia, P. Gareiss, D. Hoyer, J. S. Merkel, Q. Yan, Screenidentified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget 7, 39931-39944 (2016).
-
(2016)
Oncotarget
, vol.7
, pp. 39931-39944
-
-
Gale, M.1
Sayegh, J.2
Cao, J.3
Norcia, M.4
Gareiss, P.5
Hoyer, D.6
Merkel, J.S.7
Yan, Q.8
-
53
-
-
0027215176
-
3′ RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes
-
G. Edwalds-Gilbert, J. Prescott, E. Falck-Pedersen, 3′ RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes. Mol. Cell. Biol. 13, 3472-3480 (1993).
-
(1993)
Mol. Cell. Biol
, vol.13
, pp. 3472-3480
-
-
Edwalds-Gilbert, G.1
Prescott, J.2
Falck-Pedersen, E.3
-
54
-
-
16244422640
-
Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Gg-globin gene
-
K. E. Plant, M. J. Dye, C. Lafaille, N. J. Proudfoot, Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Gg-globin gene. Mol. Cell. Biol. 25, 3276-3285 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 3276-3285
-
-
Plant, K.E.1
Dye, M.J.2
Lafaille, C.3
Proudfoot, N.J.4
-
55
-
-
0034679725
-
Transcriptional termination and coupled polyadenylation in vitro
-
M. Yonaha, N. J. Proudfoot, Transcriptional termination and coupled polyadenylation in vitro. EMBO J. 19, 3770-3777 (2000).
-
(2000)
EMBO J
, vol.19
, pp. 3770-3777
-
-
Yonaha, M.1
Proudfoot, N.J.2
-
56
-
-
84869083379
-
Timing of transcriptional quiescence during gametogenesis is controlled by global histone H3K4 demethylation
-
M. Xu, M. Soloveychik, M. Ranger, M. Schertzberg, Z. Shah, R. Raisner, S. Venkatasubrahmanyan, K. Tsui, M. Gebbia, T. Hughes, H. van Bakel, C. Nislow, H. D. Madhani, M. D. Meneghini, Timing of transcriptional quiescence during gametogenesis is controlled by global histone H3K4 demethylation. Dev. Cell 23, 1059-1071 (2012).
-
(2012)
Dev. Cell
, vol.23
, pp. 1059-1071
-
-
Xu, M.1
Soloveychik, M.2
Ranger, M.3
Schertzberg, M.4
Shah, Z.5
Raisner, R.6
Venkatasubrahmanyan, S.7
Tsui, K.8
Gebbia, M.9
Hughes, T.10
Van Bakel, H.11
Nislow, C.12
Madhani, H.D.13
Meneghini, M.D.14
-
57
-
-
4043129097
-
Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors
-
M. C. Yu, F. Bachand, A. E. McBride, S. Komili, J. M. Casolari, P. A. Silver, Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors. Genes Dev. 18, 2024-2035 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 2024-2035
-
-
Yu, M.C.1
Bachand, F.2
McBride, A.E.3
Komili, S.4
Casolari, J.M.5
Silver, P.A.6
-
58
-
-
84887203696
-
A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation
-
K. E. Moore, S. M. Carlson, N. D. Camp, P. Cheung, R. G. James, K. F. Chua, A. Wolf-Yadlin, O. Gozani, A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation. Mol. Cell 50, 444-456 (2013).
-
(2013)
Mol. Cell
, vol.50
, pp. 444-456
-
-
Moore, K.E.1
Carlson, S.M.2
Camp, N.D.3
Cheung, P.4
James, R.G.5
Chua, K.F.6
Wolf-Yadlin, A.7
Gozani, O.8
-
59
-
-
84881113123
-
Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome
-
M. Bremang, A. Cuomo, A. M. Agresta, M. Stugiewicz, V. Spadotto, T. Bonaldi, Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome. Mol. Biosyst. 9, 2231-2247 (2013).
-
(2013)
Mol. Biosyst
, vol.9
, pp. 2231-2247
-
-
Bremang, M.1
Cuomo, A.2
Agresta, A.M.3
Stugiewicz, M.4
Spadotto, V.5
Bonaldi, T.6
-
60
-
-
77950862042
-
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
-
M. H. G. P. Raaijmakers, S. Mukherjee, S. Guo, S. Zhang, T. Kobayashi, J. A. Schoonmaker, B. L. Ebert, F. Al-Shahrour, R. P. Hasserjian, E. O. Scadden, Z. Aung, M. Matza, M. Merkenschlager, C. Lin, J. M. Rommens, D. T. Scadden, Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 464, 852-857 (2010).
-
(2010)
Nature
, vol.464
, pp. 852-857
-
-
Raaijmakers, M.H.G.P.1
Mukherjee, S.2
Guo, S.3
Zhang, S.4
Kobayashi, T.5
Schoonmaker, J.A.6
Ebert, B.L.7
Al-Shahrour, F.8
Hasserjian, R.P.9
Scadden, E.O.10
Aung, Z.11
Matza, M.12
Merkenschlager, M.13
Lin, C.14
Rommens, J.M.15
Scadden, D.T.16
-
61
-
-
84895904908
-
The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers
-
B. J. Klein, L. Piao, Y. Xi, H. Rincon-Arano, S. B. Rothbart, D. Peng, H. Wen, C. Larson, X. Zhang, X. Zheng, M. A. Cortazar, P. V. Peña, A. Mangan, D. L. Bentley, B. D. Strahl, M. Groudine, W. Li, X. Shi, T. G. Kutateladze, The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers. Cell Rep. 6, 325-335 (2014).
-
(2014)
Cell Rep
, vol.6
, pp. 325-335
-
-
Klein, B.J.1
Piao, L.2
Xi, Y.3
Rincon-Arano, H.4
Rothbart, S.B.5
Peng, D.6
Wen, H.7
Larson, C.8
Zhang, X.9
Zheng, X.10
Cortazar, M.A.11
Peña, P.V.12
Mangan, A.13
Bentley, D.L.14
Strahl, B.D.15
Groudine, M.16
Li, W.17
Shi, X.18
Kutateladze, T.G.19
-
62
-
-
84908339823
-
KDM5 interacts with Foxo to modulate cellular levels of oxidative stress
-
X. Liu, C. Greer, J. Secombe, KDM5 interacts with Foxo to modulate cellular levels of oxidative stress. PLOS Genet. 10, e1004676 (2014).
-
(2014)
PLOS Genet
, vol.10
, pp. e1004676
-
-
Liu, X.1
Greer, C.2
Secombe, J.3
-
63
-
-
84875987260
-
Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen
-
J. Sayegh, J. Cao, M. R. Zou, A. Morales, L. P. Blair, M. Norcia, D. Hoyer, A. J. Tackett, J. S. Merkel, Q. Yan, Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J. Biol. Chem. 288, 9408-9417 (2013).
-
(2013)
J. Biol. Chem
, vol.288
, pp. 9408-9417
-
-
Sayegh, J.1
Cao, J.2
Zou, M.R.3
Morales, A.4
Blair, L.P.5
Norcia, M.6
Hoyer, D.7
Tackett, A.J.8
Merkel, J.S.9
Yan, Q.10
-
64
-
-
84889595831
-
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
-
L. Wang, J. Chang, D. Varghese, M. Dellinger, S. Kumar, A. M. Best, J. Ruiz, R. Bruick, S. Peña-Llopis, J. Xu, D. J. Babinski, D. E. Frantz, R. A. Brekken, A. M. Quinn, A. Simeonov, J. Easmon, E. D. Martinez, A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat. Commun. 4, 2035 (2013).
-
(2013)
Nat. Commun
, vol.4
, pp. 2035
-
-
Wang, L.1
Chang, J.2
Varghese, D.3
Dellinger, M.4
Kumar, S.5
Best, A.M.6
Ruiz, J.7
Bruick, R.8
Peña-Llopis, S.9
Xu, J.10
Babinski, D.J.11
Frantz, D.E.12
Brekken, R.A.13
Quinn, A.M.14
Simeonov, A.15
Easmon, J.16
Martinez, E.D.17
-
65
-
-
84861182365
-
Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2, 4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor
-
L. H. Kristensen, A. L. Nielsen, C. Helgstrand, M. Lees, P. Cloos, J. S. Kastrup, K. Helin, L. Olsen, M. Gajhede, Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2, 4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. FEBS J. 279, 1905-1914 (2012).
-
(2012)
FEBS J
, vol.279
, pp. 1905-1914
-
-
Kristensen, L.H.1
Nielsen, A.L.2
Helgstrand, C.3
Lees, M.4
Cloos, P.5
Kastrup, J.S.6
Helin, K.7
Olsen, L.8
Gajhede, M.9
-
66
-
-
84969883819
-
An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells
-
M. Vinogradova, V. S. Gehling, A. Gustafson, S. Arora, C. A Tindell, C. Wilson, K. E Williamson, G. D. Guler, P. Gangurde, W. Manieri, J. Busby, E. M. Flynn, F. Lan, H.-j. Kim, S. Odate, A. G. Cochran, Y. Liu, M. Wongchenko, Y. Yang, T. K. Cheung, T. M. Maile, T. Lau, M. Costa, G. V. Hegde, E. Jackson, R. Pitti, D. Arnott, C. Bailey, S. Bellon, R. T. Cummings, B. K. Albrecht, J.-C. Harmange, J. R. Kiefer, P. Trojer, M. Classon, An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nat. Chem. Biol. 12, 531-538 (2016).
-
(2016)
Nat. Chem. Biol.
, vol.12
, pp. 531-538
-
-
Vinogradova, M.1
Gehling, V.S.2
Gustafson, A.3
Arora, S.4
Tindell, C.A.5
Wilson, C.6
Williamson, K.E.7
Guler, G.D.8
Gangurde, P.9
Manieri, W.10
Busby, J.11
Flynn, E.M.12
Lan, F.13
Kim, H.-J.14
Odate, S.15
Cochran, A.G.16
Liu, Y.17
Wongchenko, M.18
Yang, Y.19
Cheung, T.K.20
Maile, T.M.21
Lau, T.22
Costa, M.23
Hegde, G.V.24
Jackson, E.25
Pitti, R.26
Arnott, D.27
Bailey, C.28
Bellon, S.29
Cummings, R.T.30
Albrecht, B.K.31
Harmange, J.-C.32
Kiefer, J.R.33
Trojer, P.34
Classon, M.35
more..
-
67
-
-
84959422044
-
8-substituted pyrido[3, 4-d]pyrimidin-4(3H)-one derivatives as potent, cell permeable, KDM4 (JMJD2) and KDM5 (JARID1) histone lysine demethylase inhibitors
-
V. Bavetsias, R. M. Lanigan, G. F. Ruda, B. Atrash, M. G. McLaughlin, A. Tumber, N. Y. Mok, Y.-V. Le Bihan, S. Dempster, K. J. Boxall, F. Jeganathan, S. B. Hatch, P. Savitsky, S. Velupillai, T. Krojer, K. S. England, J. Sejberg, C. Thai, A. Donovan, A. Pal, G. Scozzafava, J. M. Bennett, A. Kawamura, C. Johansson, A. Szykowska, C. Gileadi, N. A. Burgess-Brown, F. von Delft, U. Oppermann, Z. Walters, J. Shipley, F. I. Raynaud, S. M. Westaway, R. K. Prinjha, O. Fedorov, R. Burke, C. J. Schofield, I. M. Westwood, C. Bountra, S. Müller, R. L.M. van Montfort, P. E. Brennan, J. Blagg, 8-substituted pyrido[3, 4-d]pyrimidin-4(3H)-one derivatives as potent, cell permeable, KDM4 (JMJD2) and KDM5 (JARID1) histone lysine demethylase inhibitors. J. Med. Chem. 59, 1388-1409 (2016).
-
(2016)
J. Med. Chem.
, vol.59
, pp. 1388-1409
-
-
Bavetsias, V.1
Lanigan, R.M.2
Ruda, G.F.3
Atrash, B.4
McLaughlin, M.G.5
Tumber, A.6
Mok, N.Y.7
Le Bihan, Y.-V.8
Dempster, S.9
Boxall, K.J.10
Jeganathan, F.11
Hatch, S.B.12
Savitsky, P.13
Velupillai, S.14
Krojer, T.15
England, K.S.16
Sejberg, J.17
Thai, C.18
Donovan, A.19
Pal, A.20
Scozzafava, G.21
Bennett, J.M.22
Kawamura, A.23
Johansson, C.24
Szykowska, A.25
Gileadi, C.26
Burgess-Brown, N.A.27
Von Delft, F.28
Oppermann, U.29
Walters, Z.30
Shipley, J.31
Raynaud, F.I.32
Westaway, S.M.33
Prinjha, R.K.34
Fedorov, O.35
Burke, R.36
Schofield, C.J.37
Westwood, I.M.38
Bountra, C.39
Müller, S.40
Van Montfort, R.L.M.41
Brennan, P.E.42
Blagg, J.43
more..
-
68
-
-
0032721092
-
Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor
-
J. Zhao, M. Kessler, S. Helmling, J. P. O'Connor, C. Moore, Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol. Cell. Biol. 19, 7733-7740 (1999).
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 7733-7740
-
-
Zhao, J.1
Kessler, M.2
Helmling, S.3
O'Connor, J.P.4
Moore, C.5
-
69
-
-
84919770754
-
The evolutionarily conserved Pol II flap loop contributes to proper transcription termination on short yeast genes
-
E. Pearson, C. Moore, The evolutionarily conserved Pol II flap loop contributes to proper transcription termination on short yeast genes. Cell Rep. 9, 821-828 (2014).
-
(2014)
Cell Rep
, vol.9
, pp. 821-828
-
-
Pearson, E.1
Moore, C.2
-
71
-
-
84859210032
-
Fast gapped-read alignment with Bowtie 2
-
B. Langmead, S. L. Salzberg, Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357-359 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 357-359
-
-
Langmead, B.1
Salzberg, S.L.2
-
72
-
-
84905049901
-
Trimmomatic: A flexible trimmer for Illumina sequence data
-
A. M. Bolger, M. Lohse, B. Usadel, Trimmomatic: A flexible trimmer for Illumina sequence data. Bioinformatics 30, 2114-2120 (2014).
-
(2014)
Bioinformatics
, vol.30
, pp. 2114-2120
-
-
Bolger, A.M.1
Lohse, M.2
Usadel, B.3
-
73
-
-
67650711619
-
A clustering approach for identification of enriched domains from histone modification ChIP-Seq data
-
C. Zang, D. E. Schones, C. Zeng, K. Cui, K. Zhao, W. Peng, A clustering approach for identification of enriched domains from histone modification ChIP-Seq data. Bioinformatics 25, 1952-1958 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 1952-1958
-
-
Zang, C.1
Schones, D.E.2
Zeng, C.3
Cui, K.4
Zhao, K.5
Peng, W.6
-
74
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
S. Heinz, C. Benner, N. Spann, E. Bertolino, Y. C. Lin, P. Laslo, J. X. Cheng, C. Murre, H. Singh, C. K. Glass, Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576 (2010).
-
(2010)
Mol. Cell
, vol.38
, pp. 576
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
Cheng, J.X.7
Murre, C.8
Singh, H.9
Glass, C.K.10
-
75
-
-
78651271733
-
Integrative genomics viewer
-
J. T. Robinson, H. Thorvaldsdóttir, W. Winckler, M. Guttman, E. S Lander, G. Getz, J. P. Mesirov, Integrative genomics viewer. Nat. Biotechnol. 29, 24-26 (2011).
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 24-26
-
-
Robinson, J.T.1
Thorvaldsdóttir, H.2
Winckler, W.3
Guttman, M.4
Lander, E.S.5
Getz, G.6
Mesirov, J.P.7
-
76
-
-
68349098404
-
RNA immunoprecipitation to determine RNA-protein associations in vivo
-
pdb.prot5234
-
L. A. Selth, C. Gilbert, J. Q. Svejstrup, RNA immunoprecipitation to determine RNA-protein associations in vivo. Cold Spring Harb. Protoc. pdb.prot5234 (2009).
-
(2009)
Cold Spring Harb. Protoc.
-
-
Selth, L.A.1
Gilbert, C.2
Svejstrup, J.Q.3
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