Apparent affinity estimates and reversal of the effects of synthetic cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by rimonabant in rhesus monkeys

Journal of Pharmacology and Experimental Therapeutics

Volumn 362, Issue 2, 2017, Pages 278-286

  Hruba, Lenka ^a   McMahon, Lance R ^a  

^a University of Texas Health Science Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 FLUOROPENTYL) 3 (1 NAPHTHOYL)INDOLE; CANNABINOID RECEPTOR AGONIST; CP 47 497; JWH 122; JWH 250; RIMONABANT; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG; (4-METHYL-1-NAPHTHYL)-(1-PENTYLINDOL-3-YL)METHANONE; 1-((5-FLUOROPENTYL)-1H-INDOL-3-YL)-(NAPHTHALEN-1-YL)METHANONE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; CP 47497; CYCLOHEXANOL DERIVATIVE; INDOLE DERIVATIVE; NAPHTHALENE DERIVATIVE; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; DRUG DISCRIMINATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; FEMALE; MALE; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; STIMULUS RESPONSE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; DISCRIMINATION LEARNING; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY;

ANIMALS; CANNABINOID RECEPTOR ANTAGONISTS; CANNABINOIDS; CYCLOHEXANOLS; DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INDOLES; MACACA MULATTA; MALE; NAPHTHALENES; PIPERIDINES; PYRAZOLES; RECEPTOR, CANNABINOID, CB1;

EID: 85024503411     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.117.240572     Document Type: Article

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